PDS5A (PDS5 cohesin associated factor A)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23244 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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PDS5 cohesin associated factor A |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PDS5A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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PIG54, SCC-112, SCC112 |
Chromosome
Chromosome number
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4 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4p14 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding differ |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||
UniProt ID | Q29RF7 | |
Protein name | Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112) | |
Protein function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is a | |
Family and domains | ||
Tissue specificity | TISSUE SPECIFICITY: Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. {ECO:0000269|PubMed:15019998}. | |
Sequence |
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Sequence length | 1337 | |
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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