PDS5A (PDS5 cohesin associated factor A)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23244 |
| Gene name | PDS5 cohesin associated factor A |
| Gene symbol | PDS5A |
| Synonyms (NCBI Gene) |
PIG54SCC-112SCC112
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| Chromosome | 4 |
| Chromosome location | 4p14 |
| Summary | The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding differ |
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miRNA
miRNA information provided by mirtarbase database.
491
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q29RF7 | |
| Protein name | Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112) | |
| Protein function | Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is a | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. {ECO:0000269|PubMed:15019998}. | |
| Sequence |
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| Sequence length | 1337 | |
| Interactions | View interactions | |
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
4
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