Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23213
Gene name Gene Name - the full gene name approved by the HGNC.	Sulfatase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SULF1
Synonyms (NCBI Gene) Gene synonyms aliases	SULF-1
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8q13.2-q13.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently

Show/Hide all(519)

miRTarBase ID	miRNA	Experiments	Reference
MIRT005970	hsa-miR-516a-3p	Northern blot, qRT-PCR, Western blot	21169410
MIRT005970	hsa-miR-516a-3p	Northern blot, qRT-PCR, Western blot	21169410
MIRT022965	hsa-miR-124-3p	Microarray	18668037
MIRT734636	hsa-miR-378a-3p	Luciferase reporter assay, Microarray, qRT-PCR	32866261
MIRT1402616	hsa-miR-548p	CLIP-seq
MIRT1402617	hsa-miR-555	CLIP-seq
MIRT1402618	hsa-miR-635	CLIP-seq
MIRT1402619	hsa-let-7a	CLIP-seq
MIRT1402620	hsa-let-7b	CLIP-seq
MIRT1402621	hsa-let-7c	CLIP-seq
MIRT1402622	hsa-let-7d	CLIP-seq
MIRT1402623	hsa-let-7e	CLIP-seq
MIRT1402624	hsa-let-7f	CLIP-seq
MIRT1402625	hsa-let-7g	CLIP-seq
MIRT1402626	hsa-let-7i	CLIP-seq
MIRT1402627	hsa-miR-1294	CLIP-seq
MIRT1402628	hsa-miR-132	CLIP-seq
MIRT1402629	hsa-miR-194	CLIP-seq
MIRT1402630	hsa-miR-202	CLIP-seq
MIRT1402631	hsa-miR-212	CLIP-seq
MIRT1402632	hsa-miR-2909	CLIP-seq
MIRT1402633	hsa-miR-4276	CLIP-seq
MIRT1402634	hsa-miR-4458	CLIP-seq
MIRT1402635	hsa-miR-4500	CLIP-seq
MIRT1402636	hsa-miR-500a	CLIP-seq
MIRT1402637	hsa-miR-501-5p	CLIP-seq
MIRT1402638	hsa-miR-548ag	CLIP-seq
MIRT1402639	hsa-miR-548ai	CLIP-seq
MIRT1402617	hsa-miR-555	CLIP-seq
MIRT1402640	hsa-miR-98	CLIP-seq
MIRT1402641	hsa-miR-1178	CLIP-seq
MIRT1402642	hsa-miR-1200	CLIP-seq
MIRT1402643	hsa-miR-137	CLIP-seq
MIRT1402644	hsa-miR-3074-5p	CLIP-seq
MIRT1402645	hsa-miR-3124-3p	CLIP-seq
MIRT1402646	hsa-miR-3140-5p	CLIP-seq
MIRT1402647	hsa-miR-3977	CLIP-seq
MIRT1402648	hsa-miR-4305	CLIP-seq
MIRT1402649	hsa-miR-4777-5p	CLIP-seq
MIRT1402650	hsa-miR-4786-3p	CLIP-seq
MIRT1402651	hsa-miR-4789-5p	CLIP-seq
MIRT1402652	hsa-miR-518d-5p	CLIP-seq
MIRT1402653	hsa-miR-519b-5p	CLIP-seq
MIRT1402654	hsa-miR-519c-5p	CLIP-seq
MIRT1402655	hsa-miR-520c-5p	CLIP-seq
MIRT1402656	hsa-miR-526a	CLIP-seq
MIRT1402616	hsa-miR-548p	CLIP-seq
MIRT1402618	hsa-miR-635	CLIP-seq
MIRT1402657	hsa-miR-656	CLIP-seq
MIRT1554314	hsa-miR-3128	CLIP-seq
MIRT1554315	hsa-miR-338-5p	CLIP-seq
MIRT1554316	hsa-miR-4470	CLIP-seq
MIRT1554317	hsa-miR-4501	CLIP-seq
MIRT1554318	hsa-miR-4720-5p	CLIP-seq
MIRT1554319	hsa-miR-4799-3p	CLIP-seq
MIRT1554320	hsa-miR-640	CLIP-seq
MIRT2120759	hsa-miR-1825	CLIP-seq
MIRT2120760	hsa-miR-199a-5p	CLIP-seq
MIRT2120761	hsa-miR-199b-5p	CLIP-seq
MIRT2120762	hsa-miR-3180-5p	CLIP-seq
MIRT2120763	hsa-miR-3545-3p	CLIP-seq
MIRT2120764	hsa-miR-3925-3p	CLIP-seq
MIRT2120765	hsa-miR-4255	CLIP-seq
MIRT2120766	hsa-miR-515-5p	CLIP-seq
MIRT2120767	hsa-miR-607	CLIP-seq
MIRT2120768	hsa-miR-665	CLIP-seq
MIRT2120769	hsa-miR-766	CLIP-seq
MIRT2433658	hsa-miR-1	CLIP-seq
MIRT2433659	hsa-miR-105	CLIP-seq
MIRT2433660	hsa-miR-1236	CLIP-seq
MIRT2433661	hsa-miR-124	CLIP-seq
MIRT2433662	hsa-miR-1245b-3p	CLIP-seq
MIRT2433663	hsa-miR-1247	CLIP-seq
MIRT2433664	hsa-miR-1256	CLIP-seq
MIRT2433665	hsa-miR-1261	CLIP-seq
MIRT2433666	hsa-miR-1264	CLIP-seq
MIRT2433667	hsa-miR-1275	CLIP-seq
MIRT2433668	hsa-miR-1297	CLIP-seq
MIRT2433669	hsa-miR-1299	CLIP-seq
MIRT2433670	hsa-miR-1304	CLIP-seq
MIRT2433671	hsa-miR-130a	CLIP-seq
MIRT2433672	hsa-miR-130b	CLIP-seq
MIRT2433673	hsa-miR-145	CLIP-seq
MIRT2433674	hsa-miR-148a	CLIP-seq
MIRT2433675	hsa-miR-148b	CLIP-seq
MIRT2433676	hsa-miR-152	CLIP-seq
MIRT2120759	hsa-miR-1825	CLIP-seq
MIRT2433677	hsa-miR-1909	CLIP-seq
MIRT2120760	hsa-miR-199a-5p	CLIP-seq
MIRT2120761	hsa-miR-199b-5p	CLIP-seq
MIRT2433678	hsa-miR-19a	CLIP-seq
MIRT2433679	hsa-miR-19b	CLIP-seq
MIRT2433680	hsa-miR-200b	CLIP-seq
MIRT2433681	hsa-miR-200c	CLIP-seq
MIRT2433682	hsa-miR-205	CLIP-seq
MIRT2433683	hsa-miR-206	CLIP-seq
MIRT2433684	hsa-miR-214	CLIP-seq
MIRT2433685	hsa-miR-2278	CLIP-seq
MIRT2433686	hsa-miR-2467-5p	CLIP-seq
MIRT2433687	hsa-miR-26a	CLIP-seq
MIRT2433688	hsa-miR-26b	CLIP-seq
MIRT2433689	hsa-miR-301a	CLIP-seq
MIRT2433690	hsa-miR-301b	CLIP-seq
MIRT1554314	hsa-miR-3128	CLIP-seq
MIRT2433691	hsa-miR-3137	CLIP-seq
MIRT2433692	hsa-miR-3162-3p	CLIP-seq
MIRT2120762	hsa-miR-3180-5p	CLIP-seq
MIRT2433693	hsa-miR-3188	CLIP-seq
MIRT2433694	hsa-miR-3189-3p	CLIP-seq
MIRT1554315	hsa-miR-338-5p	CLIP-seq
MIRT2433695	hsa-miR-3619-5p	CLIP-seq
MIRT2433696	hsa-miR-3622a-5p	CLIP-seq
MIRT2433697	hsa-miR-3666	CLIP-seq
MIRT2433698	hsa-miR-3671	CLIP-seq
MIRT2433699	hsa-miR-3673	CLIP-seq
MIRT2433700	hsa-miR-369-3p	CLIP-seq
MIRT2120764	hsa-miR-3925-3p	CLIP-seq
MIRT2433701	hsa-miR-3975	CLIP-seq
MIRT2120765	hsa-miR-4255	CLIP-seq
MIRT2433702	hsa-miR-4272	CLIP-seq
MIRT2433703	hsa-miR-429	CLIP-seq
MIRT2433704	hsa-miR-4291	CLIP-seq
MIRT2433705	hsa-miR-4295	CLIP-seq
MIRT2433706	hsa-miR-4318	CLIP-seq
MIRT2433707	hsa-miR-4423-3p	CLIP-seq
MIRT2433708	hsa-miR-4465	CLIP-seq
MIRT1554316	hsa-miR-4470	CLIP-seq
MIRT2433709	hsa-miR-4474-5p	CLIP-seq
MIRT1554317	hsa-miR-4501	CLIP-seq
MIRT2433710	hsa-miR-4519	CLIP-seq
MIRT2433711	hsa-miR-452	CLIP-seq
MIRT2433712	hsa-miR-4522	CLIP-seq
MIRT2433713	hsa-miR-454	CLIP-seq
MIRT2433714	hsa-miR-4540	CLIP-seq
MIRT2433715	hsa-miR-455-3p	CLIP-seq
MIRT2433716	hsa-miR-4665-5p	CLIP-seq
MIRT2433717	hsa-miR-4676-3p	CLIP-seq
MIRT2433718	hsa-miR-4690-5p	CLIP-seq
MIRT2433719	hsa-miR-4693-5p	CLIP-seq
MIRT2433720	hsa-miR-4703-3p	CLIP-seq
MIRT1554318	hsa-miR-4720-5p	CLIP-seq
MIRT2433721	hsa-miR-4742-5p	CLIP-seq
MIRT2433722	hsa-miR-4782-5p	CLIP-seq
MIRT1554319	hsa-miR-4799-3p	CLIP-seq
MIRT2433723	hsa-miR-4799-5p	CLIP-seq
MIRT2433724	hsa-miR-485-5p	CLIP-seq
MIRT2433725	hsa-miR-493	CLIP-seq
MIRT1402636	hsa-miR-500a	CLIP-seq
MIRT2433726	hsa-miR-506	CLIP-seq
MIRT2433727	hsa-miR-509-3p	CLIP-seq
MIRT2120766	hsa-miR-515-5p	CLIP-seq
MIRT2433728	hsa-miR-516b	CLIP-seq
MIRT2433729	hsa-miR-520a-5p	CLIP-seq
MIRT2433730	hsa-miR-525-5p	CLIP-seq
MIRT2433731	hsa-miR-548an	CLIP-seq
MIRT1402617	hsa-miR-555	CLIP-seq
MIRT2433732	hsa-miR-579	CLIP-seq
MIRT2433733	hsa-miR-605	CLIP-seq
MIRT2120767	hsa-miR-607	CLIP-seq
MIRT2433734	hsa-miR-613	CLIP-seq
MIRT1554320	hsa-miR-640	CLIP-seq
MIRT2433735	hsa-miR-761	CLIP-seq
MIRT2120769	hsa-miR-766	CLIP-seq
MIRT2433736	hsa-miR-767-5p	CLIP-seq
MIRT2433737	hsa-miR-875-3p	CLIP-seq
MIRT2433738	hsa-miR-892a	CLIP-seq
MIRT2433739	hsa-miR-922	CLIP-seq
MIRT2433684	hsa-miR-214	CLIP-seq
MIRT2433695	hsa-miR-3619-5p	CLIP-seq
MIRT2433704	hsa-miR-4291	CLIP-seq
MIRT2433735	hsa-miR-761	CLIP-seq
MIRT2460792	hsa-miR-3150b-3p	CLIP-seq
MIRT2460793	hsa-miR-3197	CLIP-seq
MIRT2460794	hsa-miR-4257	CLIP-seq
MIRT2460795	hsa-miR-4693-3p	CLIP-seq
MIRT2460796	hsa-miR-4695-5p	CLIP-seq
MIRT2460797	hsa-miR-4709-3p	CLIP-seq
MIRT2460798	hsa-miR-4784	CLIP-seq
MIRT1402619	hsa-let-7a	CLIP-seq
MIRT1402620	hsa-let-7b	CLIP-seq
MIRT1402621	hsa-let-7c	CLIP-seq
MIRT1402622	hsa-let-7d	CLIP-seq
MIRT1402623	hsa-let-7e	CLIP-seq
MIRT1402624	hsa-let-7f	CLIP-seq
MIRT1402625	hsa-let-7g	CLIP-seq
MIRT1402626	hsa-let-7i	CLIP-seq
MIRT2433658	hsa-miR-1	CLIP-seq
MIRT2433659	hsa-miR-105	CLIP-seq
MIRT2636519	hsa-miR-106a	CLIP-seq
MIRT2636520	hsa-miR-106b	CLIP-seq
MIRT1402641	hsa-miR-1178	CLIP-seq
MIRT2636521	hsa-miR-1184	CLIP-seq
MIRT2636522	hsa-miR-1231	CLIP-seq
MIRT2433660	hsa-miR-1236	CLIP-seq
MIRT2433662	hsa-miR-1245b-3p	CLIP-seq
MIRT2433663	hsa-miR-1247	CLIP-seq
MIRT2636523	hsa-miR-1251	CLIP-seq
MIRT2433664	hsa-miR-1256	CLIP-seq
MIRT2433666	hsa-miR-1264	CLIP-seq
MIRT1402627	hsa-miR-1294	CLIP-seq
MIRT2433668	hsa-miR-1297	CLIP-seq
MIRT2433669	hsa-miR-1299	CLIP-seq
MIRT2433671	hsa-miR-130a	CLIP-seq
MIRT2433672	hsa-miR-130b	CLIP-seq
MIRT2636524	hsa-miR-1323	CLIP-seq
MIRT2636525	hsa-miR-140-5p	CLIP-seq
MIRT2433673	hsa-miR-145	CLIP-seq
MIRT2433674	hsa-miR-148a	CLIP-seq
MIRT2433675	hsa-miR-148b	CLIP-seq
MIRT2433676	hsa-miR-152	CLIP-seq
MIRT2636526	hsa-miR-1587	CLIP-seq
MIRT2636527	hsa-miR-17	CLIP-seq
MIRT2120759	hsa-miR-1825	CLIP-seq
MIRT2120760	hsa-miR-199a-5p	CLIP-seq
MIRT2120761	hsa-miR-199b-5p	CLIP-seq
MIRT2433678	hsa-miR-19a	CLIP-seq
MIRT2433679	hsa-miR-19b	CLIP-seq
MIRT1402630	hsa-miR-202	CLIP-seq
MIRT2433682	hsa-miR-205	CLIP-seq
MIRT2433683	hsa-miR-206	CLIP-seq
MIRT2636528	hsa-miR-20a	CLIP-seq
MIRT2636529	hsa-miR-20b	CLIP-seq
MIRT2636530	hsa-miR-2110	CLIP-seq
MIRT2433684	hsa-miR-214	CLIP-seq
MIRT2636531	hsa-miR-216a	CLIP-seq
MIRT2636532	hsa-miR-216b	CLIP-seq
MIRT2636533	hsa-miR-2682	CLIP-seq
MIRT2433687	hsa-miR-26a	CLIP-seq
MIRT2433688	hsa-miR-26b	CLIP-seq
MIRT2636534	hsa-miR-296-5p	CLIP-seq
MIRT2433689	hsa-miR-301a	CLIP-seq
MIRT2433690	hsa-miR-301b	CLIP-seq
MIRT2636535	hsa-miR-3121-3p	CLIP-seq
MIRT2433691	hsa-miR-3137	CLIP-seq
MIRT2636536	hsa-miR-3161	CLIP-seq
MIRT2120762	hsa-miR-3180-5p	CLIP-seq
MIRT2636537	hsa-miR-3190	CLIP-seq
MIRT2636538	hsa-miR-326	CLIP-seq
MIRT2636539	hsa-miR-330-5p	CLIP-seq
MIRT2636540	hsa-miR-34a	CLIP-seq
MIRT2636541	hsa-miR-34c-5p	CLIP-seq
MIRT2636542	hsa-miR-3607-3p	CLIP-seq
MIRT2636543	hsa-miR-3613-3p	CLIP-seq
MIRT2433695	hsa-miR-3619-5p	CLIP-seq
MIRT2636544	hsa-miR-3646	CLIP-seq
MIRT2636545	hsa-miR-3647-3p	CLIP-seq
MIRT2636546	hsa-miR-3662	CLIP-seq
MIRT2433697	hsa-miR-3666	CLIP-seq
MIRT2636547	hsa-miR-3669	CLIP-seq
MIRT2433698	hsa-miR-3671	CLIP-seq
MIRT2433699	hsa-miR-3673	CLIP-seq
MIRT2636548	hsa-miR-371-5p	CLIP-seq
MIRT2636549	hsa-miR-371b-5p	CLIP-seq
MIRT2636550	hsa-miR-376a	CLIP-seq
MIRT2636551	hsa-miR-376b	CLIP-seq
MIRT2636552	hsa-miR-378	CLIP-seq
MIRT2636553	hsa-miR-378b	CLIP-seq
MIRT2636554	hsa-miR-378c	CLIP-seq
MIRT2636555	hsa-miR-378d	CLIP-seq
MIRT2636556	hsa-miR-378e	CLIP-seq
MIRT2636557	hsa-miR-378f	CLIP-seq
MIRT2636558	hsa-miR-378h	CLIP-seq
MIRT2636559	hsa-miR-378i	CLIP-seq
MIRT2120764	hsa-miR-3925-3p	CLIP-seq
MIRT2636560	hsa-miR-3973	CLIP-seq
MIRT2636561	hsa-miR-409-3p	CLIP-seq
MIRT2636562	hsa-miR-422a	CLIP-seq
MIRT2120765	hsa-miR-4255	CLIP-seq
MIRT2636563	hsa-miR-4271	CLIP-seq
MIRT1402633	hsa-miR-4276	CLIP-seq
MIRT2636564	hsa-miR-4283	CLIP-seq
MIRT2636565	hsa-miR-4288	CLIP-seq
MIRT2433704	hsa-miR-4291	CLIP-seq
MIRT2433705	hsa-miR-4295	CLIP-seq
MIRT2636566	hsa-miR-4307	CLIP-seq
MIRT2636567	hsa-miR-4432	CLIP-seq
MIRT1402634	hsa-miR-4458	CLIP-seq
MIRT2433708	hsa-miR-4465	CLIP-seq
MIRT2636568	hsa-miR-4468	CLIP-seq
MIRT2433709	hsa-miR-4474-5p	CLIP-seq
MIRT2636569	hsa-miR-4489	CLIP-seq
MIRT2636570	hsa-miR-4492	CLIP-seq
MIRT2636571	hsa-miR-4498	CLIP-seq
MIRT2636572	hsa-miR-449a	CLIP-seq
MIRT2636573	hsa-miR-449b	CLIP-seq
MIRT2636574	hsa-miR-449c	CLIP-seq
MIRT1402635	hsa-miR-4500	CLIP-seq
MIRT2636575	hsa-miR-4505	CLIP-seq
MIRT2636576	hsa-miR-4514	CLIP-seq
MIRT2433710	hsa-miR-4519	CLIP-seq
MIRT2433712	hsa-miR-4522	CLIP-seq
MIRT2433713	hsa-miR-454	CLIP-seq
MIRT2433714	hsa-miR-4540	CLIP-seq
MIRT2433715	hsa-miR-455-3p	CLIP-seq
MIRT2636577	hsa-miR-4638-3p	CLIP-seq
MIRT2636578	hsa-miR-4656	CLIP-seq
MIRT2636579	hsa-miR-4667-5p	CLIP-seq
MIRT2636580	hsa-miR-4675	CLIP-seq
MIRT2636581	hsa-miR-4692	CLIP-seq
MIRT2636582	hsa-miR-4700-5p	CLIP-seq
MIRT2433720	hsa-miR-4703-3p	CLIP-seq
MIRT2636583	hsa-miR-4725-3p	CLIP-seq
MIRT2636584	hsa-miR-4741	CLIP-seq
MIRT2636585	hsa-miR-4763-5p	CLIP-seq
MIRT2636586	hsa-miR-4774-5p	CLIP-seq
MIRT2636587	hsa-miR-4781-3p	CLIP-seq
MIRT2433722	hsa-miR-4782-5p	CLIP-seq
MIRT2433723	hsa-miR-4799-5p	CLIP-seq
MIRT2636588	hsa-miR-499-5p	CLIP-seq
MIRT1402636	hsa-miR-500a	CLIP-seq
MIRT1402637	hsa-miR-501-5p	CLIP-seq
MIRT2120766	hsa-miR-515-5p	CLIP-seq
MIRT2433728	hsa-miR-516b	CLIP-seq
MIRT2636589	hsa-miR-519a	CLIP-seq
MIRT2636590	hsa-miR-519b-3p	CLIP-seq
MIRT2636591	hsa-miR-519c-3p	CLIP-seq
MIRT2636592	hsa-miR-519d	CLIP-seq
MIRT2433729	hsa-miR-520a-5p	CLIP-seq
MIRT2636593	hsa-miR-520g	CLIP-seq
MIRT2636594	hsa-miR-520h	CLIP-seq
MIRT2433730	hsa-miR-525-5p	CLIP-seq
MIRT2636595	hsa-miR-548b-3p	CLIP-seq
MIRT2636596	hsa-miR-548c-3p	CLIP-seq
MIRT2636597	hsa-miR-548o	CLIP-seq
MIRT2636598	hsa-miR-550a	CLIP-seq
MIRT2636599	hsa-miR-576-3p	CLIP-seq
MIRT2433733	hsa-miR-605	CLIP-seq
MIRT2120767	hsa-miR-607	CLIP-seq
MIRT2433734	hsa-miR-613	CLIP-seq
MIRT2636600	hsa-miR-627	CLIP-seq
MIRT2636601	hsa-miR-632	CLIP-seq
MIRT2636602	hsa-miR-642b	CLIP-seq
MIRT2636603	hsa-miR-661	CLIP-seq
MIRT2120768	hsa-miR-665	CLIP-seq
MIRT2433735	hsa-miR-761	CLIP-seq
MIRT2636604	hsa-miR-762	CLIP-seq
MIRT2120769	hsa-miR-766	CLIP-seq
MIRT2433737	hsa-miR-875-3p	CLIP-seq
MIRT2433739	hsa-miR-922	CLIP-seq
MIRT2636605	hsa-miR-924	CLIP-seq
MIRT2636606	hsa-miR-93	CLIP-seq
MIRT1402640	hsa-miR-98	CLIP-seq
MIRT2433684	hsa-miR-214	CLIP-seq
MIRT2433695	hsa-miR-3619-5p	CLIP-seq
MIRT2433704	hsa-miR-4291	CLIP-seq
MIRT1402636	hsa-miR-500a	CLIP-seq
MIRT2120767	hsa-miR-607	CLIP-seq
MIRT2433735	hsa-miR-761	CLIP-seq
MIRT1402619	hsa-let-7a	CLIP-seq
MIRT1402620	hsa-let-7b	CLIP-seq
MIRT1402621	hsa-let-7c	CLIP-seq
MIRT1402622	hsa-let-7d	CLIP-seq
MIRT1402623	hsa-let-7e	CLIP-seq
MIRT1402624	hsa-let-7f	CLIP-seq
MIRT1402625	hsa-let-7g	CLIP-seq
MIRT1402626	hsa-let-7i	CLIP-seq
MIRT2433658	hsa-miR-1	CLIP-seq
MIRT2433659	hsa-miR-105	CLIP-seq
MIRT2636519	hsa-miR-106a	CLIP-seq
MIRT2636520	hsa-miR-106b	CLIP-seq
MIRT1402641	hsa-miR-1178	CLIP-seq
MIRT2636521	hsa-miR-1184	CLIP-seq
MIRT2636522	hsa-miR-1231	CLIP-seq
MIRT2433660	hsa-miR-1236	CLIP-seq
MIRT2433662	hsa-miR-1245b-3p	CLIP-seq
MIRT2433663	hsa-miR-1247	CLIP-seq
MIRT2636523	hsa-miR-1251	CLIP-seq
MIRT2433664	hsa-miR-1256	CLIP-seq
MIRT2433666	hsa-miR-1264	CLIP-seq
MIRT1402627	hsa-miR-1294	CLIP-seq
MIRT2433668	hsa-miR-1297	CLIP-seq
MIRT2433669	hsa-miR-1299	CLIP-seq
MIRT2433671	hsa-miR-130a	CLIP-seq
MIRT2433672	hsa-miR-130b	CLIP-seq
MIRT2636524	hsa-miR-1323	CLIP-seq
MIRT2636525	hsa-miR-140-5p	CLIP-seq
MIRT2433673	hsa-miR-145	CLIP-seq
MIRT2433674	hsa-miR-148a	CLIP-seq
MIRT2433675	hsa-miR-148b	CLIP-seq
MIRT2433676	hsa-miR-152	CLIP-seq
MIRT2636526	hsa-miR-1587	CLIP-seq
MIRT2636527	hsa-miR-17	CLIP-seq
MIRT2120759	hsa-miR-1825	CLIP-seq
MIRT2120760	hsa-miR-199a-5p	CLIP-seq
MIRT2120761	hsa-miR-199b-5p	CLIP-seq
MIRT2433678	hsa-miR-19a	CLIP-seq
MIRT2433679	hsa-miR-19b	CLIP-seq
MIRT1402630	hsa-miR-202	CLIP-seq
MIRT2433682	hsa-miR-205	CLIP-seq
MIRT2433683	hsa-miR-206	CLIP-seq
MIRT2636528	hsa-miR-20a	CLIP-seq
MIRT2636529	hsa-miR-20b	CLIP-seq
MIRT2636530	hsa-miR-2110	CLIP-seq
MIRT2433684	hsa-miR-214	CLIP-seq
MIRT2636531	hsa-miR-216a	CLIP-seq
MIRT2636532	hsa-miR-216b	CLIP-seq
MIRT2636533	hsa-miR-2682	CLIP-seq
MIRT2433687	hsa-miR-26a	CLIP-seq
MIRT2433688	hsa-miR-26b	CLIP-seq
MIRT2636534	hsa-miR-296-5p	CLIP-seq
MIRT2433689	hsa-miR-301a	CLIP-seq
MIRT2433690	hsa-miR-301b	CLIP-seq
MIRT2636535	hsa-miR-3121-3p	CLIP-seq
MIRT2433691	hsa-miR-3137	CLIP-seq
MIRT2636536	hsa-miR-3161	CLIP-seq
MIRT2120762	hsa-miR-3180-5p	CLIP-seq
MIRT2636538	hsa-miR-326	CLIP-seq
MIRT2636539	hsa-miR-330-5p	CLIP-seq
MIRT2636540	hsa-miR-34a	CLIP-seq
MIRT2636541	hsa-miR-34c-5p	CLIP-seq
MIRT2636542	hsa-miR-3607-3p	CLIP-seq
MIRT2636543	hsa-miR-3613-3p	CLIP-seq
MIRT2433695	hsa-miR-3619-5p	CLIP-seq
MIRT2636544	hsa-miR-3646	CLIP-seq
MIRT2636545	hsa-miR-3647-3p	CLIP-seq
MIRT2636546	hsa-miR-3662	CLIP-seq
MIRT2433697	hsa-miR-3666	CLIP-seq
MIRT2636547	hsa-miR-3669	CLIP-seq
MIRT2433698	hsa-miR-3671	CLIP-seq
MIRT2433699	hsa-miR-3673	CLIP-seq
MIRT2636548	hsa-miR-371-5p	CLIP-seq
MIRT2636549	hsa-miR-371b-5p	CLIP-seq
MIRT2692419	hsa-miR-374c	CLIP-seq
MIRT2636550	hsa-miR-376a	CLIP-seq
MIRT2636551	hsa-miR-376b	CLIP-seq
MIRT2636552	hsa-miR-378	CLIP-seq
MIRT2636553	hsa-miR-378b	CLIP-seq
MIRT2636554	hsa-miR-378c	CLIP-seq
MIRT2636555	hsa-miR-378d	CLIP-seq
MIRT2636556	hsa-miR-378e	CLIP-seq
MIRT2636557	hsa-miR-378f	CLIP-seq
MIRT2636558	hsa-miR-378h	CLIP-seq
MIRT2636559	hsa-miR-378i	CLIP-seq
MIRT2120764	hsa-miR-3925-3p	CLIP-seq
MIRT2636560	hsa-miR-3973	CLIP-seq
MIRT2636561	hsa-miR-409-3p	CLIP-seq
MIRT2636562	hsa-miR-422a	CLIP-seq
MIRT2120765	hsa-miR-4255	CLIP-seq
MIRT2636563	hsa-miR-4271	CLIP-seq
MIRT1402633	hsa-miR-4276	CLIP-seq
MIRT2636564	hsa-miR-4283	CLIP-seq
MIRT2636565	hsa-miR-4288	CLIP-seq
MIRT2433704	hsa-miR-4291	CLIP-seq
MIRT2433705	hsa-miR-4295	CLIP-seq
MIRT2636567	hsa-miR-4432	CLIP-seq
MIRT1402634	hsa-miR-4458	CLIP-seq
MIRT2433708	hsa-miR-4465	CLIP-seq
MIRT2636568	hsa-miR-4468	CLIP-seq
MIRT2433709	hsa-miR-4474-5p	CLIP-seq
MIRT2636569	hsa-miR-4489	CLIP-seq
MIRT2636570	hsa-miR-4492	CLIP-seq
MIRT2636571	hsa-miR-4498	CLIP-seq
MIRT2636572	hsa-miR-449a	CLIP-seq
MIRT2636573	hsa-miR-449b	CLIP-seq
MIRT2636574	hsa-miR-449c	CLIP-seq
MIRT1402635	hsa-miR-4500	CLIP-seq
MIRT2636575	hsa-miR-4505	CLIP-seq
MIRT2636576	hsa-miR-4514	CLIP-seq
MIRT2433710	hsa-miR-4519	CLIP-seq
MIRT2433712	hsa-miR-4522	CLIP-seq
MIRT2433713	hsa-miR-454	CLIP-seq
MIRT2433714	hsa-miR-4540	CLIP-seq
MIRT2433715	hsa-miR-455-3p	CLIP-seq
MIRT2636577	hsa-miR-4638-3p	CLIP-seq
MIRT2636578	hsa-miR-4656	CLIP-seq
MIRT2636579	hsa-miR-4667-5p	CLIP-seq
MIRT2636580	hsa-miR-4675	CLIP-seq
MIRT2636581	hsa-miR-4692	CLIP-seq
MIRT2636582	hsa-miR-4700-5p	CLIP-seq
MIRT2433720	hsa-miR-4703-3p	CLIP-seq
MIRT2636583	hsa-miR-4725-3p	CLIP-seq
MIRT2636584	hsa-miR-4741	CLIP-seq
MIRT2636585	hsa-miR-4763-5p	CLIP-seq
MIRT2636586	hsa-miR-4774-5p	CLIP-seq
MIRT2636587	hsa-miR-4781-3p	CLIP-seq
MIRT2433722	hsa-miR-4782-5p	CLIP-seq
MIRT2433723	hsa-miR-4799-5p	CLIP-seq
MIRT2636588	hsa-miR-499-5p	CLIP-seq
MIRT1402636	hsa-miR-500a	CLIP-seq
MIRT1402637	hsa-miR-501-5p	CLIP-seq
MIRT2120766	hsa-miR-515-5p	CLIP-seq
MIRT2433728	hsa-miR-516b	CLIP-seq
MIRT2636589	hsa-miR-519a	CLIP-seq
MIRT2636590	hsa-miR-519b-3p	CLIP-seq
MIRT2636591	hsa-miR-519c-3p	CLIP-seq
MIRT2636592	hsa-miR-519d	CLIP-seq
MIRT2433729	hsa-miR-520a-5p	CLIP-seq
MIRT2636593	hsa-miR-520g	CLIP-seq
MIRT2636594	hsa-miR-520h	CLIP-seq
MIRT2433730	hsa-miR-525-5p	CLIP-seq
MIRT2692420	hsa-miR-548ac	CLIP-seq
MIRT2692421	hsa-miR-548ae	CLIP-seq
MIRT2692422	hsa-miR-548aj	CLIP-seq
MIRT2692423	hsa-miR-548am	CLIP-seq
MIRT2636595	hsa-miR-548b-3p	CLIP-seq
MIRT2636596	hsa-miR-548c-3p	CLIP-seq
MIRT2692424	hsa-miR-548d-3p	CLIP-seq
MIRT2636597	hsa-miR-548o	CLIP-seq
MIRT2692425	hsa-miR-548x	CLIP-seq
MIRT2692426	hsa-miR-548z	CLIP-seq
MIRT2636598	hsa-miR-550a	CLIP-seq
MIRT2636599	hsa-miR-576-3p	CLIP-seq
MIRT2433733	hsa-miR-605	CLIP-seq
MIRT2120767	hsa-miR-607	CLIP-seq
MIRT2433734	hsa-miR-613	CLIP-seq
MIRT2636600	hsa-miR-627	CLIP-seq
MIRT2636601	hsa-miR-632	CLIP-seq
MIRT2636602	hsa-miR-642b	CLIP-seq
MIRT2692427	hsa-miR-655	CLIP-seq
MIRT2636603	hsa-miR-661	CLIP-seq
MIRT2120768	hsa-miR-665	CLIP-seq
MIRT2433735	hsa-miR-761	CLIP-seq
MIRT2636604	hsa-miR-762	CLIP-seq
MIRT2120769	hsa-miR-766	CLIP-seq
MIRT2433737	hsa-miR-875-3p	CLIP-seq
MIRT2433739	hsa-miR-922	CLIP-seq
MIRT2636605	hsa-miR-924	CLIP-seq
MIRT2636606	hsa-miR-93	CLIP-seq
MIRT1402640	hsa-miR-98	CLIP-seq

Show/Hide all(72)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001822	Process	Kidney development	IEA
GO:0001822	Process	Kidney development	ISS
GO:0001937	Process	Negative regulation of endothelial cell proliferation	IDA	16778174
GO:0002063	Process	Chondrocyte development	IEA
GO:0002063	Process	Chondrocyte development	ISS
GO:0003094	Process	Glomerular filtration	IEA
GO:0003094	Process	Glomerular filtration	ISS
GO:0004065	Function	Arylsulfatase activity	IDA	12368295
GO:0004065	Function	Arylsulfatase activity	IEA
GO:0004065	Function	Arylsulfatase activity	IMP	19520866
GO:0005509	Function	Calcium ion binding	IEA
GO:0005539	Function	Glycosaminoglycan binding	IBA
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	HDA	22664934
GO:0005615	Component	Extracellular space	IDA	19666466
GO:0005615	Component	Extracellular space	NAS	12368295
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA	18687675
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005795	Component	Golgi stack	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0006915	Process	Apoptotic process	IEA
GO:0008449	Function	N-acetylglucosamine-6-sulfatase activity	IBA
GO:0008449	Function	N-acetylglucosamine-6-sulfatase activity	IDA	12686563, 18687675, 19666466
GO:0008449	Function	N-acetylglucosamine-6-sulfatase activity	IEA
GO:0008449	Function	N-acetylglucosamine-6-sulfatase activity	IMP	19520866
GO:0008484	Function	Sulfuric ester hydrolase activity	IEA
GO:0009986	Component	Cell surface	IBA
GO:0009986	Component	Cell surface	IDA	12368295, 12686563, 18687675, 19520866, 19666466
GO:0009986	Component	Cell surface	IEA
GO:0010575	Process	Positive regulation of vascular endothelial growth factor production	IBA
GO:0010575	Process	Positive regulation of vascular endothelial growth factor production	IEA
GO:0010575	Process	Positive regulation of vascular endothelial growth factor production	ISS
GO:0014846	Process	Esophagus smooth muscle contraction	IEA
GO:0014846	Process	Esophagus smooth muscle contraction	ISS
GO:0016525	Process	Negative regulation of angiogenesis	IDA	16778174
GO:0016787	Function	Hydrolase activity	IEA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IBA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IDA	19520866
GO:0030201	Process	Heparan sulfate proteoglycan metabolic process	IBA
GO:0030201	Process	Heparan sulfate proteoglycan metabolic process	IDA	18687675, 19666466, 19822709
GO:0030201	Process	Heparan sulfate proteoglycan metabolic process	IEA
GO:0030201	Process	Heparan sulfate proteoglycan metabolic process	NAS	12368295
GO:0030336	Process	Negative regulation of cell migration	IMP	21266348
GO:0030513	Process	Positive regulation of BMP signaling pathway	IMP	20479257
GO:0031012	Component	Extracellular matrix	HDA	28327460
GO:0032836	Process	Glomerular basement membrane development	IBA
GO:0032836	Process	Glomerular basement membrane development	IEA
GO:0032836	Process	Glomerular basement membrane development	ISS
GO:0035860	Process	Glial cell-derived neurotrophic factor receptor signaling pathway	IEA
GO:0035860	Process	Glial cell-derived neurotrophic factor receptor signaling pathway	ISS
GO:0040036	Process	Regulation of fibroblast growth factor receptor signaling pathway	IMP	21266348
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IBA
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IEA
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IMP	20479257
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	ISS
GO:0045121	Component	Membrane raft	IDA	19520866
GO:0046872	Function	Metal ion binding	IEA
GO:0048010	Process	Vascular endothelial growth factor receptor signaling pathway	IDA	16778174
GO:0048706	Process	Embryonic skeletal system development	IEA
GO:0048706	Process	Embryonic skeletal system development	ISS
GO:0051216	Process	Cartilage development	IEA
GO:0051216	Process	Cartilage development	ISS
GO:0060348	Process	Bone development	IEA
GO:0060348	Process	Bone development	ISS
GO:0060384	Process	Innervation	IEA
GO:0060384	Process	Innervation	ISS
GO:0060686	Process	Negative regulation of prostatic bud formation	IEA
GO:0060686	Process	Negative regulation of prostatic bud formation	ISS

MIM	HGNC	e!Ensembl
610012	20391	ENSG00000137573

Protein

UniProt ID

Q8IWU6

Protein name

Extracellular sulfatase Sulf-1 (hSulf-1) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]

Protein function

Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (PubMed:12368295, PubMed:12686563). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin (PubMed:12368295

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00884	Sulfatase	43 → 374	Sulfatase	Family
PF12548	DUF3740	534 → 679	Sulfatase protein	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed at highest levels in testis, stomach, skeletal muscle, lung, kidney, pancreas, small intestine and colon. It is also detected in normal ovarian surface epithelial cells. Down-regulation seen in ovarian carcinoma cell lines, o

Sequence

MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSL
QVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAM
HEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKE
KHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPN
ASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNML
VETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVL
NIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLR
KKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPS
DLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHT
RQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLA
DSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNL
REVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENN
RRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLR
TVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQ
CNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG

Sequence length

871

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Anophthalmia/Microphthalmia-Esophageal Atresia Syndrome	Anophthalmia-microphthalmia syndrome	N/A	N/A	ClinVar
Cervical Cancer	Cervical cancer	N/A	N/A	GWAS
Crohn Disease	Crohn's disease	N/A	N/A	GWAS
Ovarian cancer	Ovarian cancer	Loss of ZNF587B and SULF1 contributed to cisplatin resistance in ovarian cancer cell lines based on Genome-scale CRISPR/Cas9 screening	31218106	CBGDA

Show/Hide Text Mining Associations (51)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Abortion Habitual	Associate	24322345
Adenocarcinoma	Associate	38250763
Adenocarcinoma of Lung	Associate	21599997
Adenoma	Associate	30175151
Alveolitis Extrinsic Allergic	Associate	37800807
Bone Diseases	Inhibit	32413029
Brain Neoplasms	Stimulate	28525382
Breast Neoplasms	Stimulate	21599997
Breast Neoplasms	Associate	24911625, 30236106, 32377705
Carcinogenesis	Associate	29991755
Carcinoma Hepatocellular	Associate	21104785
Carcinoma Intraductal Noninfiltrating	Associate	18928525, 30236106
Carcinoma Non Small Cell Lung	Associate	32432744
Carcinoma Pancreatic Ductal	Associate	33114263
Carcinoma Renal Cell	Stimulate	21599997
Cardiomyopathy Hypertrophic	Associate	34362365
Cardiovascular Diseases	Associate	37881939
Cerebrovascular Disorders	Associate	37881939
Colonic Neoplasms	Associate	31612481
Colorectal Neoplasms	Associate	21228115, 23372686
Congenital Hyperinsulinism	Associate	23869231
Dupuytren Contracture	Associate	21732829
Ehlers Danlos syndrome type 3	Associate	27518164
Esophageal Achalasia	Associate	36614110
Fibrosis	Associate	39354547
Glioma	Associate	29104277
Heart Failure	Associate	37073135
Hypertension	Associate	23325143
Idiopathic Pulmonary Fibrosis	Stimulate	39354547
Infections	Associate	20084279
Leukemia Large Granular Lymphocytic	Associate	35015834
Leukemia Myeloid Acute	Stimulate	21599997
Leukemia Prolymphocytic	Stimulate	21599997
Lung Neoplasms	Associate	37073135
Mesothelioma Malignant	Associate	26210886
Multiple Sclerosis	Associate	32398079
Neoplasm Metastasis	Associate	23722107, 28525382, 29991755
Neoplasms	Associate	16857057, 21104785, 23722107, 28525382, 29843217, 30175151, 30236106
Neoplasms	Inhibit	21214932, 21599997
Ovarian Neoplasms	Associate	21214932, 33227705
Ovarian Neoplasms	Inhibit	21214932
Pancreatic Neoplasms	Associate	17460759, 29843217
Peritoneal Fibrosis	Associate	23418565
Pleural Effusion Malignant	Inhibit	26210886
Prostatic Hyperplasia	Inhibit	17044071
Prostatic Neoplasms	Associate	32413029
Pulmonary Fibrosis	Associate	39354547
Stomach Neoplasms	Associate	22524839, 23722107, 35328635
Urethral Neoplasms	Stimulate	28525382
Urinary Bladder Neoplasms	Associate	28525382, 35450397
Uterine Cervical Dysplasia	Associate	20084279

SULF1 (sulfatase 1)