XPO7 (exportin 7)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23039 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Exportin 7 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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XPO7 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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EXP7, RANBP16 |
Chromosome
Chromosome number
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8 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8p21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9UIA9 | ||||||||||
Protein name | Exportin-7 (Exp7) (Ran-binding protein 16) | ||||||||||
Protein function | Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex ( | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Strong expression in testis, thyroid and bone marrow, low expression in lung, liver and small intestine, no expression in thymus, and remaining tissues studied have moderate expression. Expressed in red blood cells; overexpressed in re | ||||||||||
Sequence |
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Sequence length | 1087 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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