PHLDA1 (pleckstrin homology like domain family A member 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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22822 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Pleckstrin homology like domain family A member 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PHLDA1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DT1P1B11, PHRIP, TDAG51 |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q21.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||
| UniProt ID | Q8WV24 | |
| Protein name | Pleckstrin homology-like domain family A member 1 (Apoptosis-associated nuclear protein) (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (Proline- and histidine-rich protein) (T-cell death-associated gene 51 protein) | |
| Protein function | Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level). {ECO:0000269|PubMed:12384558, ECO:0000269|PubM | |
| Sequence |
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| Sequence length | 401 | |
| Interactions | View interactions | |
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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