ITGA11 (integrin subunit alpha 11)

Gene

• Entrez ID: 22801
• Gene name: Integrin subunit alpha 11
• Gene symbol: ITGA11
• Synonyms (NCBI Gene): HsT18964
• Chromosome: 15
• Chromosome location: 15q23
• Summary: This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005675	hsa-miR-29a-3p	Luciferase reporter assay, Microarray, Northern blot, qRT-PCR	20971881
MIRT005675	hsa-miR-29a-3p	Luciferase reporter assay, Microarray, Northern blot, qRT-PCR	20971881
MIRT608811	hsa-miR-2682-5p	HITS-CLIP	23313552
MIRT608810	hsa-miR-34b-5p	HITS-CLIP	23313552
MIRT608809	hsa-miR-449c-5p	HITS-CLIP	23313552
MIRT608808	hsa-miR-4302	HITS-CLIP	23313552
MIRT608807	hsa-miR-1827	HITS-CLIP	23313552
MIRT608246	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT608806	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT608805	hsa-miR-3612	HITS-CLIP	23313552
MIRT608804	hsa-miR-650	HITS-CLIP	23313552
MIRT608803	hsa-miR-34a-5p	HITS-CLIP	23313552
MIRT608802	hsa-miR-34c-5p	HITS-CLIP	23313552
MIRT608801	hsa-miR-449a	HITS-CLIP	23313552
MIRT608800	hsa-miR-449b-5p	HITS-CLIP	23313552
MIRT608249	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT608799	hsa-miR-2278	HITS-CLIP	23313552
MIRT608798	hsa-miR-6757-5p	HITS-CLIP	23313552
MIRT608811	hsa-miR-2682-5p	HITS-CLIP	24906430
MIRT608810	hsa-miR-34b-5p	HITS-CLIP	24906430
MIRT608809	hsa-miR-449c-5p	HITS-CLIP	24906430
MIRT608808	hsa-miR-4302	HITS-CLIP	24906430
MIRT608807	hsa-miR-1827	HITS-CLIP	24906430
MIRT608806	hsa-miR-6499-3p	HITS-CLIP	24906430
MIRT608805	hsa-miR-3612	HITS-CLIP	24906430
MIRT608804	hsa-miR-650	HITS-CLIP	24906430
MIRT608803	hsa-miR-34a-5p	HITS-CLIP	24906430
MIRT608802	hsa-miR-34c-5p	HITS-CLIP	24906430
MIRT608801	hsa-miR-449a	HITS-CLIP	24906430
MIRT608800	hsa-miR-449b-5p	HITS-CLIP	24906430
MIRT608249	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT608799	hsa-miR-2278	HITS-CLIP	24906430
MIRT608246	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT608798	hsa-miR-6757-5p	HITS-CLIP	24906430
MIRT608257	hsa-miR-6760-5p	HITS-CLIP	24906430
MIRT608256	hsa-miR-1321	HITS-CLIP	24906430
MIRT608254	hsa-miR-4739	HITS-CLIP	24906430
MIRT608255	hsa-miR-4756-5p	HITS-CLIP	24906430
MIRT608253	hsa-miR-149-3p	HITS-CLIP	24906430
MIRT608252	hsa-miR-4728-5p	HITS-CLIP	24906430
MIRT608251	hsa-miR-6785-5p	HITS-CLIP	24906430
MIRT608250	hsa-miR-6883-5p	HITS-CLIP	24906430
MIRT608249	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT608247	hsa-miR-3162-5p	HITS-CLIP	24906430
MIRT608248	hsa-miR-135b-3p	HITS-CLIP	24906430
MIRT608246	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT576458	hsa-miR-1321	PAR-CLIP	26701625
MIRT576445	hsa-miR-135b-3p	PAR-CLIP	26701625
MIRT576454	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT576446	hsa-miR-3162-5p	PAR-CLIP	26701625
MIRT576453	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT576457	hsa-miR-4739	PAR-CLIP	26701625
MIRT576456	hsa-miR-4756-5p	PAR-CLIP	26701625
MIRT576444	hsa-miR-574-5p	PAR-CLIP	26701625
MIRT576455	hsa-miR-6732-5p	PAR-CLIP	26701625
MIRT576450	hsa-miR-6752-5p	PAR-CLIP	26701625
MIRT576459	hsa-miR-6760-5p	PAR-CLIP	26701625
MIRT576452	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT576449	hsa-miR-6842-5p	PAR-CLIP	26701625
MIRT576447	hsa-miR-6867-5p	PAR-CLIP	26701625
MIRT576451	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT576448	hsa-miR-7110-5p	PAR-CLIP	26701625
MIRT576458	hsa-miR-1321	PAR-CLIP	27292025
MIRT576445	hsa-miR-135b-3p	PAR-CLIP	27292025
MIRT576454	hsa-miR-149-3p	PAR-CLIP	27292025
MIRT576446	hsa-miR-3162-5p	PAR-CLIP	27292025
MIRT576453	hsa-miR-4728-5p	PAR-CLIP	27292025
MIRT576457	hsa-miR-4739	PAR-CLIP	27292025
MIRT576456	hsa-miR-4756-5p	PAR-CLIP	27292025
MIRT576444	hsa-miR-574-5p	PAR-CLIP	27292025
MIRT576459	hsa-miR-6760-5p	PAR-CLIP	27292025
MIRT576452	hsa-miR-6785-5p	PAR-CLIP	27292025
MIRT576447	hsa-miR-6867-5p	PAR-CLIP	27292025
MIRT576451	hsa-miR-6883-5p	PAR-CLIP	27292025
MIRT576458	hsa-miR-1321	HITS-CLIP	27418678
MIRT576445	hsa-miR-135b-3p	HITS-CLIP	27418678
MIRT608807	hsa-miR-1827	HITS-CLIP	27418678
MIRT608807	hsa-miR-1827	HITS-CLIP	27418678
MIRT608799	hsa-miR-2278	HITS-CLIP	27418678
MIRT608799	hsa-miR-2278	HITS-CLIP	27418678
MIRT608811	hsa-miR-2682-5p	HITS-CLIP	27418678
MIRT608811	hsa-miR-2682-5p	HITS-CLIP	27418678
MIRT576446	hsa-miR-3162-5p	HITS-CLIP	27418678
MIRT608803	hsa-miR-34a-5p	HITS-CLIP	27418678
MIRT608803	hsa-miR-34a-5p	HITS-CLIP	27418678
MIRT608810	hsa-miR-34b-5p	HITS-CLIP	27418678
MIRT608810	hsa-miR-34b-5p	HITS-CLIP	27418678
MIRT608802	hsa-miR-34c-5p	HITS-CLIP	27418678
MIRT608802	hsa-miR-34c-5p	HITS-CLIP	27418678
MIRT608805	hsa-miR-3612	HITS-CLIP	27418678
MIRT608805	hsa-miR-3612	HITS-CLIP	27418678
MIRT608808	hsa-miR-4302	HITS-CLIP	27418678
MIRT608808	hsa-miR-4302	HITS-CLIP	27418678
MIRT608801	hsa-miR-449a	HITS-CLIP	27418678
MIRT608801	hsa-miR-449a	HITS-CLIP	27418678
MIRT608800	hsa-miR-449b-5p	HITS-CLIP	27418678
MIRT608800	hsa-miR-449b-5p	HITS-CLIP	27418678
MIRT608809	hsa-miR-449c-5p	HITS-CLIP	27418678
MIRT608809	hsa-miR-449c-5p	HITS-CLIP	27418678
MIRT576457	hsa-miR-4739	HITS-CLIP	27418678
MIRT576456	hsa-miR-4756-5p	HITS-CLIP	27418678
MIRT576444	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT576444	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608806	hsa-miR-6499-3p	HITS-CLIP	27418678
MIRT608806	hsa-miR-6499-3p	HITS-CLIP	27418678
MIRT608804	hsa-miR-650	HITS-CLIP	27418678
MIRT608804	hsa-miR-650	HITS-CLIP	27418678
MIRT608798	hsa-miR-6757-5p	HITS-CLIP	27418678
MIRT608798	hsa-miR-6757-5p	HITS-CLIP	27418678
MIRT576459	hsa-miR-6760-5p	HITS-CLIP	27418678
MIRT576447	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT576447	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT735539	hsa-miR-516b-5p	Luciferase reporter assay, Western blotting, Microarray, Immunoprecipitaion (IP), qRT-PCR	33174014
MIRT608811	hsa-miR-2682-5p	HITS-CLIP	23313552
MIRT608810	hsa-miR-34b-5p	HITS-CLIP	23313552
MIRT608809	hsa-miR-449c-5p	HITS-CLIP	23313552
MIRT608808	hsa-miR-4302	HITS-CLIP	23313552
MIRT608807	hsa-miR-1827	HITS-CLIP	23313552
MIRT576444	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT608806	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT608805	hsa-miR-3612	HITS-CLIP	23313552
MIRT608804	hsa-miR-650	HITS-CLIP	23313552
MIRT608803	hsa-miR-34a-5p	HITS-CLIP	23313552
MIRT608802	hsa-miR-34c-5p	HITS-CLIP	23313552
MIRT608801	hsa-miR-449a	HITS-CLIP	23313552
MIRT608800	hsa-miR-449b-5p	HITS-CLIP	23313552
MIRT576447	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT608799	hsa-miR-2278	HITS-CLIP	23313552
MIRT608798	hsa-miR-6757-5p	HITS-CLIP	23313552
MIRT1073377	hsa-miR-1184	CLIP-seq
MIRT1073378	hsa-miR-2682	CLIP-seq
MIRT1073379	hsa-miR-29a	CLIP-seq
MIRT1073380	hsa-miR-29b	CLIP-seq
MIRT1073381	hsa-miR-29c	CLIP-seq
MIRT1073382	hsa-miR-34a	CLIP-seq
MIRT1073383	hsa-miR-370	CLIP-seq
MIRT1073384	hsa-miR-384	CLIP-seq
MIRT1073385	hsa-miR-449b	CLIP-seq
MIRT1073386	hsa-miR-449c	CLIP-seq
MIRT1073387	hsa-miR-4755-3p	CLIP-seq
MIRT1073377	hsa-miR-1184	CLIP-seq
MIRT1550252	hsa-miR-1207-3p	CLIP-seq
MIRT1550253	hsa-miR-122	CLIP-seq
MIRT1550254	hsa-miR-1225-3p	CLIP-seq
MIRT1550255	hsa-miR-1237	CLIP-seq
MIRT1550256	hsa-miR-1254	CLIP-seq
MIRT1550257	hsa-miR-1262	CLIP-seq
MIRT1550258	hsa-miR-1299	CLIP-seq
MIRT1550259	hsa-miR-134	CLIP-seq
MIRT1550260	hsa-miR-143	CLIP-seq
MIRT1550261	hsa-miR-1915	CLIP-seq
MIRT1550262	hsa-miR-2110	CLIP-seq
MIRT1550263	hsa-miR-2277-3p	CLIP-seq
MIRT1550264	hsa-miR-2355-3p	CLIP-seq
MIRT1550265	hsa-miR-3116	CLIP-seq
MIRT1550266	hsa-miR-3118	CLIP-seq
MIRT1550267	hsa-miR-3164	CLIP-seq
MIRT1550268	hsa-miR-3202	CLIP-seq
MIRT1550269	hsa-miR-3664-3p	CLIP-seq
MIRT1550270	hsa-miR-3675-5p	CLIP-seq
MIRT1550271	hsa-miR-3689a-3p	CLIP-seq
MIRT1550272	hsa-miR-3689c	CLIP-seq
MIRT1550273	hsa-miR-3944-5p	CLIP-seq
MIRT1550274	hsa-miR-423-3p	CLIP-seq
MIRT1550275	hsa-miR-4254	CLIP-seq
MIRT1550276	hsa-miR-4271	CLIP-seq
MIRT1550277	hsa-miR-4323	CLIP-seq
MIRT1550278	hsa-miR-4419a	CLIP-seq
MIRT1550279	hsa-miR-4436a	CLIP-seq
MIRT1550280	hsa-miR-4481	CLIP-seq
MIRT1550281	hsa-miR-4510	CLIP-seq
MIRT1550282	hsa-miR-4651	CLIP-seq
MIRT1550283	hsa-miR-4654	CLIP-seq
MIRT1550284	hsa-miR-4690-5p	CLIP-seq
MIRT1550285	hsa-miR-4701-3p	CLIP-seq
MIRT1550286	hsa-miR-4725-3p	CLIP-seq
MIRT1550287	hsa-miR-4745-5p	CLIP-seq
MIRT1550288	hsa-miR-4747-5p	CLIP-seq
MIRT1550289	hsa-miR-4769-5p	CLIP-seq
MIRT1550290	hsa-miR-4770	CLIP-seq
MIRT1550291	hsa-miR-4782-5p	CLIP-seq
MIRT1550292	hsa-miR-4802-5p	CLIP-seq
MIRT1550293	hsa-miR-486-3p	CLIP-seq
MIRT1550294	hsa-miR-516a-3p	CLIP-seq
MIRT1550295	hsa-miR-516b	CLIP-seq
MIRT1550296	hsa-miR-608	CLIP-seq
MIRT1550297	hsa-miR-648	CLIP-seq
MIRT1550298	hsa-miR-676	CLIP-seq
MIRT1550299	hsa-miR-875-3p	CLIP-seq
MIRT1550258	hsa-miR-1299	CLIP-seq
MIRT2018093	hsa-miR-1305	CLIP-seq
MIRT2018094	hsa-miR-3613-3p	CLIP-seq
MIRT1550278	hsa-miR-4419a	CLIP-seq
MIRT1550281	hsa-miR-4510	CLIP-seq
MIRT1550284	hsa-miR-4690-5p	CLIP-seq
MIRT2018095	hsa-miR-4742-3p	CLIP-seq
MIRT2018096	hsa-miR-4775	CLIP-seq
MIRT1550291	hsa-miR-4782-5p	CLIP-seq
MIRT1550295	hsa-miR-516b	CLIP-seq
MIRT2018097	hsa-miR-590-3p	CLIP-seq
MIRT2018098	hsa-miR-607	CLIP-seq
MIRT1550257	hsa-miR-1262	CLIP-seq
MIRT2249965	hsa-miR-1301	CLIP-seq
MIRT2249966	hsa-miR-4436b-3p	CLIP-seq
MIRT2249967	hsa-miR-4660	CLIP-seq
MIRT1550285	hsa-miR-4701-3p	CLIP-seq
MIRT2249968	hsa-miR-5047	CLIP-seq
MIRT1073378	hsa-miR-2682	CLIP-seq
MIRT1073382	hsa-miR-34a	CLIP-seq
MIRT1550271	hsa-miR-3689a-3p	CLIP-seq
MIRT1550272	hsa-miR-3689c	CLIP-seq
MIRT1073385	hsa-miR-449b	CLIP-seq
MIRT1073386	hsa-miR-449c	CLIP-seq
MIRT1073377	hsa-miR-1184	CLIP-seq
MIRT1550254	hsa-miR-1225-3p	CLIP-seq
MIRT2553426	hsa-miR-124	CLIP-seq
MIRT2553427	hsa-miR-129-3p	CLIP-seq
MIRT2553428	hsa-miR-1298	CLIP-seq
MIRT2553429	hsa-miR-1323	CLIP-seq
MIRT1550261	hsa-miR-1915	CLIP-seq
MIRT1550264	hsa-miR-2355-3p	CLIP-seq
MIRT2553430	hsa-miR-2392	CLIP-seq
MIRT2553431	hsa-miR-2467-5p	CLIP-seq
MIRT2553432	hsa-miR-3145-5p	CLIP-seq
MIRT2553433	hsa-miR-3162-3p	CLIP-seq
MIRT2553434	hsa-miR-3178	CLIP-seq
MIRT2553435	hsa-miR-3189-3p	CLIP-seq
MIRT2553436	hsa-miR-326	CLIP-seq
MIRT2553437	hsa-miR-330-5p	CLIP-seq
MIRT2553438	hsa-miR-33a	CLIP-seq
MIRT2553439	hsa-miR-33b	CLIP-seq
MIRT2553440	hsa-miR-34c-3p	CLIP-seq
MIRT2553441	hsa-miR-3605-5p	CLIP-seq
MIRT2553442	hsa-miR-3607-5p	CLIP-seq
MIRT2553443	hsa-miR-3622a-5p	CLIP-seq
MIRT2553444	hsa-miR-3657	CLIP-seq
MIRT1073383	hsa-miR-370	CLIP-seq
MIRT2553445	hsa-miR-3714	CLIP-seq
MIRT2553446	hsa-miR-371b-5p	CLIP-seq
MIRT2553447	hsa-miR-3910	CLIP-seq
MIRT2553448	hsa-miR-3940-5p	CLIP-seq
MIRT2553449	hsa-miR-4260	CLIP-seq
MIRT2553450	hsa-miR-4269	CLIP-seq
MIRT2553451	hsa-miR-4270	CLIP-seq
MIRT1550277	hsa-miR-4323	CLIP-seq
MIRT2553452	hsa-miR-4441	CLIP-seq
MIRT2553453	hsa-miR-4450	CLIP-seq
MIRT2553454	hsa-miR-4486	CLIP-seq
MIRT2553455	hsa-miR-4507	CLIP-seq
MIRT2553456	hsa-miR-4645-5p	CLIP-seq
MIRT2553457	hsa-miR-4669	CLIP-seq
MIRT2553458	hsa-miR-4673	CLIP-seq
MIRT1073387	hsa-miR-4755-3p	CLIP-seq
MIRT2553459	hsa-miR-4768-5p	CLIP-seq
MIRT2553460	hsa-miR-4777-3p	CLIP-seq
MIRT1550293	hsa-miR-486-3p	CLIP-seq
MIRT2553461	hsa-miR-506	CLIP-seq
MIRT2553462	hsa-miR-508-5p	CLIP-seq
MIRT1550295	hsa-miR-516b	CLIP-seq
MIRT2553463	hsa-miR-532-5p	CLIP-seq
MIRT2553464	hsa-miR-548o	CLIP-seq
MIRT2553465	hsa-miR-635	CLIP-seq
MIRT1550298	hsa-miR-676	CLIP-seq
MIRT2553466	hsa-miR-765	CLIP-seq
MIRT2553426	hsa-miR-124	CLIP-seq
MIRT2553427	hsa-miR-129-3p	CLIP-seq
MIRT2553428	hsa-miR-1298	CLIP-seq
MIRT2553429	hsa-miR-1323	CLIP-seq
MIRT1550264	hsa-miR-2355-3p	CLIP-seq
MIRT2553430	hsa-miR-2392	CLIP-seq
MIRT2553432	hsa-miR-3145-5p	CLIP-seq
MIRT2553434	hsa-miR-3178	CLIP-seq
MIRT2553435	hsa-miR-3189-3p	CLIP-seq
MIRT2553436	hsa-miR-326	CLIP-seq
MIRT2553437	hsa-miR-330-5p	CLIP-seq
MIRT2553438	hsa-miR-33a	CLIP-seq
MIRT2553439	hsa-miR-33b	CLIP-seq
MIRT2553440	hsa-miR-34c-3p	CLIP-seq
MIRT2553441	hsa-miR-3605-5p	CLIP-seq
MIRT2553442	hsa-miR-3607-5p	CLIP-seq
MIRT2553443	hsa-miR-3622a-5p	CLIP-seq
MIRT2553444	hsa-miR-3657	CLIP-seq
MIRT2553445	hsa-miR-3714	CLIP-seq
MIRT2553446	hsa-miR-371b-5p	CLIP-seq
MIRT2553447	hsa-miR-3910	CLIP-seq
MIRT2553448	hsa-miR-3940-5p	CLIP-seq
MIRT2553449	hsa-miR-4260	CLIP-seq
MIRT2553450	hsa-miR-4269	CLIP-seq
MIRT2553453	hsa-miR-4450	CLIP-seq
MIRT2553454	hsa-miR-4486	CLIP-seq
MIRT2553455	hsa-miR-4507	CLIP-seq
MIRT2553456	hsa-miR-4645-5p	CLIP-seq
MIRT2553457	hsa-miR-4669	CLIP-seq
MIRT2553458	hsa-miR-4673	CLIP-seq
MIRT1073387	hsa-miR-4755-3p	CLIP-seq
MIRT2553459	hsa-miR-4768-5p	CLIP-seq
MIRT2553460	hsa-miR-4777-3p	CLIP-seq
MIRT1550293	hsa-miR-486-3p	CLIP-seq
MIRT2553461	hsa-miR-506	CLIP-seq
MIRT2553462	hsa-miR-508-5p	CLIP-seq
MIRT1550295	hsa-miR-516b	CLIP-seq
MIRT2553463	hsa-miR-532-5p	CLIP-seq
MIRT2553464	hsa-miR-548o	CLIP-seq
MIRT2553465	hsa-miR-635	CLIP-seq
MIRT1550298	hsa-miR-676	CLIP-seq
MIRT2553466	hsa-miR-765	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001649	Process	Osteoblast differentiation	HDA	16210410
GO:0005518	Function	Collagen binding	IMP	11518510
GO:0005886	Component	Plasma membrane	TAS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IDA	11518510
GO:0006929	Process	Substrate-dependent cell migration	IMP	11518510
GO:0007155	Process	Cell adhesion	TAS	10486209
GO:0007160	Process	Cell-matrix adhesion	IMP	11518510, 24823363
GO:0007229	Process	Integrin-mediated signaling pathway	IMP	24823363
GO:0007517	Process	Muscle organ development	TAS	10464311
GO:0008305	Component	Integrin complex	TAS	10486209
GO:0016020	Component	Membrane	HDA	16210410
GO:0030198	Process	Extracellular matrix organization	TAS
GO:0033627	Process	Cell adhesion mediated by integrin	IMP	11518510
GO:0034681	Component	Integrin alpha11-beta1 complex	IDA	24823363
GO:0038064	Function	Collagen receptor activity	IMP	11518510
GO:0038065	Process	Collagen-activated signaling pathway	IMP	11518510
GO:0046872	Function	Metal ion binding	IEA
GO:0098639	Function	Collagen binding involved in cell-matrix adhesion	IMP	24823363

Other IDs

• MIM: 604789
• HGNC: 6136
• e!Ensembl: ENSG00000137809

Protein

• UniProt ID: Q9UKX5
• Protein name: Integrin alpha-11
• Protein function: Integrin alpha-11/beta-1 is a receptor for collagen.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00092	VWA	164 → 344	von Willebrand factor type A domain	Domain
  PF01839	FG-GAP	480 → 518	FG-GAP repeat	Repeat
  PF01839	FG-GAP	542 → 577	FG-GAP repeat	Repeat
  PF08441	Integrin_alpha2	635 → 1067	Integrin alpha	Family

• Tissue specificity: TISSUE SPECIFICITY: According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain,
• Sequence:

  MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGA
  PLETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLA
  CSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVE
  VQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTET
  RTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVL
  GYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNET
  SFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKN
  HGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYF
  GSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNA
  RFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATG
  LQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCK
  RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAV
  LLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNG
  CNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAV
  EATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFF
  RAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFT
  RSSSLSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL
  KLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEI
  NFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQV
  PIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRREPGLDPTPKVLE

• Sequence length: 1188

Pathways

KEGG:

PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Regulation of actin cytoskeleton
Cytoskeleton in muscle cells
Human papillomavirus infection
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy

Reactome:

Integrin cell surface interactions

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Attention deficit hyperactivity disorder	Attention deficit hyperactivity disorder	rs786205019	18839057

Unknown
Disease term	Disease name	Evidence	References	Source
Mental depression	Major Depressive Disorder		23377640	ClinVar
Attention Deficit Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder			GWAS
Mental Depression	Mental Depression			GWAS
Uterine Fibroids	Uterine Fibroids			GWAS
Diabetes	Diabetes			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Aortic Aneurysm Abdominal	Associate	40275351
Bardet Biedl Syndrome	Associate	10464311
Breast Neoplasms	Associate	31605508
Carcinoma Non Small Cell Lung	Associate	31778288, 33174014, 33682233
Carotid Artery Diseases	Associate	29595698
Cognition Disorders	Associate	36737481
Esophageal Neoplasms	Associate	35813220
Gingival Overgrowth	Associate	32455102
Intracranial Aneurysm	Associate	40275351
Leiomyoma	Associate	24520080
Lichen Planus Oral	Associate	27699902
Lung Neoplasms	Associate	27121382, 31778288
Multiple Myeloma	Associate	25881608
Myocardial Infarction	Associate	33054494
Neoplasms	Associate	25354783, 27699902, 31605508, 31778288, 33682233
Neoplasms	Inhibit	34769388
Ovarian Neoplasms	Associate	32878513
Squamous Cell Carcinoma of Head and Neck	Associate	27699902