RRAS2 (RAS related 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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22800 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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RAS related 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RRAS2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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NS12, TC21 |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11p15.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathway |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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| Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P62070 | ||||||||||
| Protein name | Ras-related protein R-Ras2 (EC 3.6.5.2) (Ras-like protein TC21) (Teratocarcinoma oncogene) | ||||||||||
| Protein function | GTP-binding protein with GTPase activity, involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes (PubMed:31130282, PubMed:31130285, PubMed:39809765). Regulates craniofacial development (PubMed:31 | ||||||||||
| PDB | 2ERY , 9B4Q , 9B4S | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas. {ECO:0000269|PubMed:8052619}. | ||||||||||
| Sequence |
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| Sequence length | 204 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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