Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	22800
Gene name	RAS related 2
Gene symbol	RRAS2
Synonyms (NCBI Gene)	NS12TC21
Chromosome	11
Chromosome location	11p15.2
Summary	This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathway

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SNP ID	Visualize variation	Clinical significance	Consequence
rs113954997	T>A,C	Pathogenic	Missense variant, 5 prime UTR variant, coding sequence variant
rs782457908	C>T	Pathogenic	Missense variant, coding sequence variant, 5 prime UTR variant
rs1591495767	->ACGCCGCCC	Pathogenic	Genic upstream transcript variant, coding sequence variant, inframe insertion, upstream transcript variant, intron variant
rs1591495776	->CCCCCGCCG	Pathogenic	Genic upstream transcript variant, coding sequence variant, inframe insertion, upstream transcript variant, intron variant
rs1591495779	C>A	Pathogenic	Genic upstream transcript variant, coding sequence variant, upstream transcript variant, missense variant, intron variant

322

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miRTarBase ID	miRNA	Experiments	Reference
MIRT022861	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT025875	hsa-miR-7-5p	Sequencing	20371350
MIRT028141	hsa-miR-93-5p	Sequencing	20371350
MIRT029816	hsa-miR-26b-5p	Microarray	19088304
MIRT031260	hsa-miR-19b-3p	Sequencing	20371350
MIRT053416	hsa-miR-624-3p	Microarray	23807165
MIRT438004	hsa-miR-23b-3p	Luciferase reporter assay	24391759
MIRT438004	hsa-miR-23b-3p	Luciferase reporter assay	24391759
MIRT468899	hsa-miR-223-3p	HITS-CLIP	21572407
MIRT468898	hsa-miR-548n	HITS-CLIP	21572407
MIRT468897	hsa-miR-548az-5p	HITS-CLIP	21572407
MIRT468896	hsa-miR-548t-5p	HITS-CLIP	21572407
MIRT485131	hsa-miR-3609	HITS-CLIP	21572407
MIRT485132	hsa-miR-548ah-5p	HITS-CLIP	21572407
MIRT468895	hsa-miR-935	HITS-CLIP	21572407
MIRT468894	hsa-miR-4697-3p	HITS-CLIP	21572407
MIRT468893	hsa-miR-580-3p	HITS-CLIP	21572407
MIRT468899	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT468898	hsa-miR-548n	PAR-CLIP	20371350
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT468895	hsa-miR-935	PAR-CLIP	20371350
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	20371350
MIRT468893	hsa-miR-580-3p	PAR-CLIP	20371350
MIRT485131	hsa-miR-3609	PAR-CLIP	20371350
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT571685	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571684	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571683	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571682	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571681	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571680	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571679	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT028141	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571678	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT571677	hsa-miR-1255b-2-3p	PAR-CLIP	20371350
MIRT571676	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT571675	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT571674	hsa-miR-549a	PAR-CLIP	20371350
MIRT571673	hsa-miR-4504	PAR-CLIP	20371350
MIRT571672	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT031260	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT571671	hsa-miR-3161	PAR-CLIP	20371350
MIRT571670	hsa-miR-599	PAR-CLIP	20371350
MIRT468899	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT468898	hsa-miR-548n	PAR-CLIP	20371350
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT468895	hsa-miR-935	PAR-CLIP	20371350
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	20371350
MIRT468893	hsa-miR-580-3p	PAR-CLIP	20371350
MIRT025875	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT265276	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT554576	hsa-miR-944	PAR-CLIP	20371350
MIRT554575	hsa-miR-1252-5p	PAR-CLIP	20371350
MIRT025875	hsa-miR-7-5p	PAR-CLIP	21572407
MIRT265276	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT554576	hsa-miR-944	PAR-CLIP	21572407
MIRT554575	hsa-miR-1252-5p	PAR-CLIP	21572407
MIRT554574	hsa-miR-7848-3p	PAR-CLIP	21572407
MIRT554573	hsa-miR-2681-5p	PAR-CLIP	21572407
MIRT468899	hsa-miR-223-3p	PAR-CLIP	21572407
MIRT468898	hsa-miR-548n	PAR-CLIP	21572407
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT468895	hsa-miR-935	PAR-CLIP	21572407
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	21572407
MIRT468893	hsa-miR-580-3p	PAR-CLIP	21572407
MIRT468899	hsa-miR-223-3p	PAR-CLIP	21572407
MIRT468898	hsa-miR-548n	PAR-CLIP	21572407
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT485131	hsa-miR-3609	PAR-CLIP	21572407
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT468895	hsa-miR-935	PAR-CLIP	21572407
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	21572407
MIRT468893	hsa-miR-580-3p	PAR-CLIP	21572407
MIRT534558	hsa-miR-3662	PAR-CLIP	22012620
MIRT534557	hsa-miR-106a-3p	PAR-CLIP	22012620
MIRT468899	hsa-miR-223-3p	PAR-CLIP	22012620
MIRT468898	hsa-miR-548n	PAR-CLIP	22012620
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT468895	hsa-miR-935	PAR-CLIP	22012620
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	22012620
MIRT468893	hsa-miR-580-3p	PAR-CLIP	22012620
MIRT468899	hsa-miR-223-3p	PAR-CLIP	23592263
MIRT468898	hsa-miR-548n	PAR-CLIP	23592263
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT485131	hsa-miR-3609	PAR-CLIP	23592263
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT468895	hsa-miR-935	PAR-CLIP	23592263
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	23592263
MIRT468893	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT468899	hsa-miR-223-3p	PAR-CLIP	23592263
MIRT468898	hsa-miR-548n	PAR-CLIP	23592263
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT485131	hsa-miR-3609	PAR-CLIP	23592263
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT468895	hsa-miR-935	PAR-CLIP	23592263
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	23592263
MIRT468893	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT468899	hsa-miR-223-3p	PAR-CLIP	23592263
MIRT468898	hsa-miR-548n	PAR-CLIP	23592263
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT468895	hsa-miR-935	PAR-CLIP	23592263
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	23592263
MIRT468893	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT468899	hsa-miR-223-3p	PAR-CLIP	26701625
MIRT485131	hsa-miR-3609	PAR-CLIP	26701625
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	26701625
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	26701625
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	26701625
MIRT468898	hsa-miR-548n	PAR-CLIP	26701625
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	26701625
MIRT468893	hsa-miR-580-3p	PAR-CLIP	26701625
MIRT468895	hsa-miR-935	PAR-CLIP	26701625
MIRT468899	hsa-miR-223-3p	PAR-CLIP	27292025
MIRT485131	hsa-miR-3609	PAR-CLIP	27292025
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	27292025
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	27292025
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	27292025
MIRT468898	hsa-miR-548n	PAR-CLIP	27292025
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	27292025
MIRT468893	hsa-miR-580-3p	PAR-CLIP	27292025
MIRT468895	hsa-miR-935	PAR-CLIP	27292025
MIRT468899	hsa-miR-223-3p	HITS-CLIP	21572407
MIRT468898	hsa-miR-548n	HITS-CLIP	21572407
MIRT468897	hsa-miR-548az-5p	HITS-CLIP	21572407
MIRT468896	hsa-miR-548t-5p	HITS-CLIP	21572407
MIRT485131	hsa-miR-3609	HITS-CLIP	21572407
MIRT485132	hsa-miR-548ah-5p	HITS-CLIP	21572407
MIRT468895	hsa-miR-935	HITS-CLIP	21572407
MIRT468894	hsa-miR-4697-3p	HITS-CLIP	21572407
MIRT468893	hsa-miR-580-3p	HITS-CLIP	21572407
MIRT468899	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT468898	hsa-miR-548n	PAR-CLIP	20371350
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT468895	hsa-miR-935	PAR-CLIP	20371350
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	20371350
MIRT468893	hsa-miR-580-3p	PAR-CLIP	20371350
MIRT485131	hsa-miR-3609	PAR-CLIP	20371350
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT571685	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT571684	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT571683	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT571682	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT571681	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT571680	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT571679	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT028141	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT571678	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT571677	hsa-miR-1255b-2-3p	PAR-CLIP	20371350
MIRT571676	hsa-miR-142-5p	PAR-CLIP	20371350
MIRT571675	hsa-miR-5590-3p	PAR-CLIP	20371350
MIRT571674	hsa-miR-549a	PAR-CLIP	20371350
MIRT571673	hsa-miR-4504	PAR-CLIP	20371350
MIRT571672	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT031260	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT571671	hsa-miR-3161	PAR-CLIP	20371350
MIRT571670	hsa-miR-599	PAR-CLIP	20371350
MIRT468899	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT468898	hsa-miR-548n	PAR-CLIP	20371350
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT468895	hsa-miR-935	PAR-CLIP	20371350
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	20371350
MIRT468893	hsa-miR-580-3p	PAR-CLIP	20371350
MIRT025875	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT265276	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT554576	hsa-miR-944	PAR-CLIP	20371350
MIRT554575	hsa-miR-1252-5p	PAR-CLIP	20371350
MIRT025875	hsa-miR-7-5p	PAR-CLIP	21572407
MIRT265276	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT554576	hsa-miR-944	PAR-CLIP	21572407
MIRT554575	hsa-miR-1252-5p	PAR-CLIP	21572407
MIRT554574	hsa-miR-7848-3p	PAR-CLIP	21572407
MIRT554573	hsa-miR-2681-5p	PAR-CLIP	21572407
MIRT468899	hsa-miR-223-3p	PAR-CLIP	21572407
MIRT468898	hsa-miR-548n	PAR-CLIP	21572407
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT468895	hsa-miR-935	PAR-CLIP	21572407
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	21572407
MIRT468893	hsa-miR-580-3p	PAR-CLIP	21572407
MIRT468899	hsa-miR-223-3p	PAR-CLIP	21572407
MIRT468898	hsa-miR-548n	PAR-CLIP	21572407
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT485131	hsa-miR-3609	PAR-CLIP	21572407
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT468895	hsa-miR-935	PAR-CLIP	21572407
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	21572407
MIRT468893	hsa-miR-580-3p	PAR-CLIP	21572407
MIRT534558	hsa-miR-3662	PAR-CLIP	22012620
MIRT534557	hsa-miR-106a-3p	PAR-CLIP	22012620
MIRT468899	hsa-miR-223-3p	PAR-CLIP	22012620
MIRT468898	hsa-miR-548n	PAR-CLIP	22012620
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT468895	hsa-miR-935	PAR-CLIP	22012620
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	22012620
MIRT468893	hsa-miR-580-3p	PAR-CLIP	22012620
MIRT468899	hsa-miR-223-3p	PAR-CLIP	23592263
MIRT468898	hsa-miR-548n	PAR-CLIP	23592263
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT485131	hsa-miR-3609	PAR-CLIP	23592263
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT468895	hsa-miR-935	PAR-CLIP	23592263
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	23592263
MIRT468893	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT468899	hsa-miR-223-3p	PAR-CLIP	23592263
MIRT468898	hsa-miR-548n	PAR-CLIP	23592263
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT485131	hsa-miR-3609	PAR-CLIP	23592263
MIRT485132	hsa-miR-548ah-5p	PAR-CLIP	23592263
MIRT468895	hsa-miR-935	PAR-CLIP	23592263
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	23592263
MIRT468893	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT468899	hsa-miR-223-3p	PAR-CLIP	23592263
MIRT468898	hsa-miR-548n	PAR-CLIP	23592263
MIRT468897	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT468896	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT468895	hsa-miR-935	PAR-CLIP	23592263
MIRT468894	hsa-miR-4697-3p	PAR-CLIP	23592263
MIRT468893	hsa-miR-580-3p	PAR-CLIP	23592263
MIRT1319421	hsa-miR-1225-5p	CLIP-seq
MIRT1319422	hsa-miR-1276	CLIP-seq
MIRT1319423	hsa-miR-134	CLIP-seq
MIRT1319424	hsa-miR-140-3p	CLIP-seq
MIRT1319425	hsa-miR-193a-3p	CLIP-seq
MIRT1319426	hsa-miR-193b	CLIP-seq
MIRT1319427	hsa-miR-3118	CLIP-seq
MIRT1319428	hsa-miR-3168	CLIP-seq
MIRT1319429	hsa-miR-3646	CLIP-seq
MIRT1319430	hsa-miR-3926	CLIP-seq
MIRT1319431	hsa-miR-3978	CLIP-seq
MIRT1319432	hsa-miR-4308	CLIP-seq
MIRT1319433	hsa-miR-4426	CLIP-seq
MIRT1319434	hsa-miR-4521	CLIP-seq
MIRT1319435	hsa-miR-4647	CLIP-seq
MIRT1319436	hsa-miR-4662b	CLIP-seq
MIRT1319437	hsa-miR-4725-5p	CLIP-seq
MIRT1319438	hsa-miR-504	CLIP-seq
MIRT1319439	hsa-miR-548m	CLIP-seq
MIRT1319440	hsa-miR-548s	CLIP-seq
MIRT1319441	hsa-miR-548t	CLIP-seq
MIRT1319442	hsa-miR-587	CLIP-seq
MIRT1319443	hsa-miR-634	CLIP-seq
MIRT1319444	hsa-miR-654-3p	CLIP-seq
MIRT1319445	hsa-miR-875-3p	CLIP-seq
MIRT1319446	hsa-miR-1244	CLIP-seq
MIRT1319423	hsa-miR-134	CLIP-seq
MIRT1319425	hsa-miR-193a-3p	CLIP-seq
MIRT1319426	hsa-miR-193b	CLIP-seq
MIRT1319447	hsa-miR-223	CLIP-seq
MIRT1319427	hsa-miR-3118	CLIP-seq
MIRT1319448	hsa-miR-3137	CLIP-seq
MIRT1319449	hsa-miR-3164	CLIP-seq
MIRT1319450	hsa-miR-3187-3p	CLIP-seq
MIRT1319451	hsa-miR-3686	CLIP-seq
MIRT1319452	hsa-miR-3692	CLIP-seq
MIRT1319453	hsa-miR-382	CLIP-seq
MIRT1319430	hsa-miR-3926	CLIP-seq
MIRT1319431	hsa-miR-3978	CLIP-seq
MIRT1319432	hsa-miR-4308	CLIP-seq
MIRT1319454	hsa-miR-4328	CLIP-seq
MIRT1319433	hsa-miR-4426	CLIP-seq
MIRT1319455	hsa-miR-4435	CLIP-seq
MIRT1319456	hsa-miR-4436b-5p	CLIP-seq
MIRT1319457	hsa-miR-4501	CLIP-seq
MIRT1319458	hsa-miR-4529-5p	CLIP-seq
MIRT1319435	hsa-miR-4647	CLIP-seq
MIRT1319459	hsa-miR-4652-3p	CLIP-seq
MIRT1319436	hsa-miR-4662b	CLIP-seq
MIRT1319460	hsa-miR-4701-5p	CLIP-seq
MIRT1319461	hsa-miR-4703-3p	CLIP-seq
MIRT1319437	hsa-miR-4725-5p	CLIP-seq
MIRT1319438	hsa-miR-504	CLIP-seq
MIRT1319462	hsa-miR-520d-5p	CLIP-seq
MIRT1319463	hsa-miR-524-5p	CLIP-seq
MIRT1319464	hsa-miR-548ah	CLIP-seq
MIRT1319440	hsa-miR-548s	CLIP-seq
MIRT1319441	hsa-miR-548t	CLIP-seq
MIRT1319465	hsa-miR-570	CLIP-seq
MIRT1319466	hsa-miR-580	CLIP-seq
MIRT1319442	hsa-miR-587	CLIP-seq
MIRT1319467	hsa-miR-588	CLIP-seq
MIRT1319468	hsa-miR-656	CLIP-seq
MIRT1319445	hsa-miR-875-3p	CLIP-seq
MIRT1319441	hsa-miR-548t	CLIP-seq
MIRT2094915	hsa-miR-3591-5p	CLIP-seq
MIRT2094916	hsa-miR-4255	CLIP-seq
MIRT2094917	hsa-miR-513a-3p	CLIP-seq
MIRT1319447	hsa-miR-223	CLIP-seq
MIRT2319313	hsa-miR-3613-5p	CLIP-seq
MIRT1319464	hsa-miR-548ah	CLIP-seq
MIRT1319441	hsa-miR-548t	CLIP-seq
MIRT1319466	hsa-miR-580	CLIP-seq
MIRT1319441	hsa-miR-548t	CLIP-seq
MIRT1319447	hsa-miR-223	CLIP-seq
MIRT2393894	hsa-miR-526b	CLIP-seq
MIRT1319464	hsa-miR-548ah	CLIP-seq
MIRT1319441	hsa-miR-548t	CLIP-seq
MIRT2393895	hsa-miR-578	CLIP-seq
MIRT1319466	hsa-miR-580	CLIP-seq
MIRT1319422	hsa-miR-1276	CLIP-seq
MIRT2614971	hsa-miR-200b	CLIP-seq
MIRT2614972	hsa-miR-200c	CLIP-seq
MIRT2614973	hsa-miR-203	CLIP-seq
MIRT2614974	hsa-miR-3675-3p	CLIP-seq
MIRT2614975	hsa-miR-374c	CLIP-seq
MIRT2614976	hsa-miR-429	CLIP-seq
MIRT1319444	hsa-miR-654-3p	CLIP-seq
MIRT2614977	hsa-miR-655	CLIP-seq
MIRT1319444	hsa-miR-654-3p	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
BTF3	Repression	17312387

Show/Hide all (29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000166	Function	Nucleotide binding	IEA
GO:0001649	Process	Osteoblast differentiation	HDA	16210410
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IDA	31130282
GO:0003924	Function	GTPase activity	IEA
GO:0003924	Function	GTPase activity	TAS	10777492
GO:0005515	Function	Protein binding	IPI	12620389, 19060904, 28514442, 31515488, 32296183, 33961781
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IEA
GO:0005783	Component	Endoplasmic reticulum	NAS	10777492
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	28406396
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	NAS	10777492
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007165	Process	Signal transduction	IEA
GO:0007265	Process	Ras protein signal transduction	IDA	31130282
GO:0007265	Process	Ras protein signal transduction	IEA
GO:0007265	Process	Ras protein signal transduction	IEA
GO:0016020	Component	Membrane	HDA	16210410
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019003	Function	GDP binding	IBA
GO:0036135	Process	Schwann cell migration	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1900149	Process	Positive regulation of Schwann cell migration	IEA

MIM	HGNC	e!Ensembl
600098	17271	ENSG00000133818

P62070

Protein name

Ras-related protein R-Ras2 (EC 3.6.5.2) (Ras-like protein TC21) (Teratocarcinoma oncogene)

Protein function

GTP-binding protein with GTPase activity, involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes (PubMed:31130282, PubMed:31130285, PubMed:39809765). Regulates craniofacial development (PubMed:31

PDB

2ERY , 9B4Q , 9B4S

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00071	Ras	16 → 177	Ras family	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas. {ECO:0000269|PubMed:8052619}.

Sequence

MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
QECPPSPEPTRKEKDKKGCHCVIF

Sequence length

204

Interactions

View interactions

	KEGG
	MAPK signaling pathway Ras signaling pathway cAMP signaling pathway Phospholipase D signaling pathway Mitophagy - animal Autophagy - animal Cellular senescence Apelin signaling pathway C-type lectin receptor signaling pathway Regulation of actin cytoskeleton Proteoglycans in cancer

Show/Hide Causal Diseases (8)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Adenocarcinoma of the large intestine	Likely pathogenic; Pathogenic	rs2493951813	RCV006254361
Central nervous system germ cell tumor	Pathogenic	rs1591495779	RCV006254325
Germinoma	Likely pathogenic; Pathogenic	rs2134048726, rs1591495779	RCV006254311 RCV006254148
Noonan syndrome	Likely pathogenic; Pathogenic	rs2134048726, rs113954997, rs782457908, rs1591495767, rs1591495776, rs1591495779	RCV003153250 RCV000852398 RCV000852397 RCV000852399 RCV000852395 RCV000852396
Noonan syndrome 12	Pathogenic; Likely pathogenic	rs1591495779, rs2493951813, rs113954997, rs782457908, rs1591495767	RCV002272974 RCV005254745 RCV000010054 RCV000853183 RCV000853184
Ovarian neoplasm	Pathogenic	rs113954997	RCV001072115
RASopathy	Likely pathogenic	rs782457908	RCV004760768
RRAS2-related disorder	Likely pathogenic	rs782457908	RCV003411705

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Embryonal rhabdomyosarcoma	Uncertain significance	rs2493951813	RCV006254351
Malignant tumor of urinary bladder	Uncertain significance	rs571234555	RCV005930601
See cases	Uncertain significance	rs2493951813	RCV003128494

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Astrocytoma	Stimulate	24148564
Breast Neoplasms	Stimulate	24148564
Developmental Disabilities	Associate	37942564
Epstein Barr Virus Infections	Associate	37434198
Esophageal Neoplasms	Associate	22919244
Esophageal Squamous Cell Carcinoma	Associate	22919244
Genetic Diseases Inborn	Associate	33686258
Glioblastoma	Stimulate	24148564
Hydrops Fetalis	Associate	33686258
Hyperplasia	Stimulate	24148564
Leiomyosarcoma	Associate	9703274
Leukemia Lymphocytic Chronic B Cell	Associate	38067115
Lymphocytosis	Inhibit	38067115
Lymphoma	Stimulate	24148564
Neoplasms	Stimulate	24148564
Neoplasms	Associate	36476833
Nervous System Diseases	Associate	24148564
Neurofibrosarcoma	Associate	34530870
Noonan Syndrome	Associate	31130282, 33686258, 37942564
Oligodendroglioma	Stimulate	24148564
Ovarian Neoplasms	Associate	8052619, 9703274
Rhabdomyosarcoma Embryonal	Associate	37942564
Skin Neoplasms	Associate	24391759

RRAS2 (RAS related 2)