Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
222611
Gene name Gene Name - the full gene name approved by the HGNC.
Adhesion G protein-coupled receptor F2, pseudogene
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ADGRF2P
Synonyms (NCBI Gene) Gene synonyms aliases
ADGRF2, GPR111, PGR20, hGPCR35
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p12.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT754716 hsa-miR-1249-5p PAR-CLIP 26701625
MIRT754706 hsa-miR-1321 PAR-CLIP 26701625
MIRT754719 hsa-miR-149-3p PAR-CLIP 26701625
MIRT755282 hsa-miR-3185 PAR-CLIP 26701625
MIRT754710 hsa-miR-4419a PAR-CLIP 26701625
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity IEA
GO:0007166 Process Cell surface receptor signaling pathway IEA
GO:0007186 Process G protein-coupled receptor signaling pathway IEA
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620872 18991 HGNC
Protein
UniProt ID Q8IZF7
Protein name Putative adhesion G protein-coupled receptor F2P (Adhesion G-protein coupled receptor F2) (G-protein coupled receptor 111) (G-protein coupled receptor PGR20)
Protein function Orphan receptor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01825 GPS 392 435 GPCR proteolysis site, GPS, motif Motif
PF00002 7tm_2 443 690 7 transmembrane receptor (Secretin family) Family
Tissue specificity TISSUE SPECIFICITY: High expression in kidney. Up-regulated in lung adenocarcinomas and prostate cancers. {ECO:0000269|PubMed:20149256}.
Sequence
MGLTAYGNRRVQPGELPFGANLTLIHTRAQPVICSKLLLTKRVSPISFFLSKFQNSWGED
GWVQLDQLPSPNAVSSDQVHCSAGCTHRKCGWAASKSKEKVPARPHGVCDGVCTDYSQCT
QPCPPDTQGNMGFSCRQKTWHKITDTCQTLNALNIFEEDSRLVQPFEDNIKISVYTGKSE
TITDMLLQKCPTDLSCVIRNIQQSPWIPGNIAVIVQLLHNISTAIWTGVDEAKMQSYSTI
ANHILNSKSISNWTFIPDRNSSYILLHSVNSFARRLFIDKHPVDISDVFIHTMGTTISGD
NIGKNFTFSMRINDTSNEVTGRVLISRDELRKVPSPSQVISIAFPTIGAILEASLLENVT
VNGLVLSAILPKELKRISLIFEKISKSEERRTQCVGWHSVENRWDQQACKMIQENSQQAV
CKCRPSKLFTSFSIL
MSPHILESLILTYITYVGLGISICSLILCLSIEVLVWSQVTKTEI
TYLRHVCIVNIAATLLMADVWFIVASFLSGPITHHKGCVAATFFVHFFYLSVFFWMLAKA
LLILYGIMIVFHTLPKSVLVASLFSVGYGCPLAIAAITVAATEPGKGYLRPEICWLNWDM
TKALLAFVIPALAIVVVNLITVTLVIVKTQRAAIGNSMFQEVRAIVRISKNIAILTPLLG
LTWGFGVATVIDDRSLAFHIIFSLLNAFQV
SPDASDQVQSERIHEDVL
Sequence length 708
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Alzheimer disease Alzheimer`s Disease rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039
View all (65 more)
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