ZBTB7C (zinc finger and BTB domain containing 7C)

Gene

• Entrez ID: 201501
• Gene name: Zinc finger and BTB domain containing 7C
• Gene symbol: ZBTB7C
• Synonyms (NCBI Gene): APM-1, APM1, ZBTB36, ZNF857C
• Chromosome: 18
• Chromosome location: 18q21.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018542	hsa-miR-335-5p	Microarray	18185580
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT642849	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT642849	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT642848	hsa-miR-1972	HITS-CLIP	23824327
MIRT642847	hsa-miR-4650-5p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT642849	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT642849	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT642848	hsa-miR-1972	HITS-CLIP	23824327
MIRT642847	hsa-miR-4650-5p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT621567	hsa-miR-8485	HITS-CLIP	23824327
MIRT621566	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT621565	hsa-miR-106b-3p	HITS-CLIP	23824327
MIRT756287	hsa-miR-26a-5p	Luciferase reporter assay, Western blotting, qRT-PCR	37562773
MIRT1504787	hsa-miR-1229	CLIP-seq
MIRT1504788	hsa-miR-1238	CLIP-seq
MIRT1504789	hsa-miR-1321	CLIP-seq
MIRT1504790	hsa-miR-1538	CLIP-seq
MIRT1504791	hsa-miR-1827	CLIP-seq
MIRT1504792	hsa-miR-185	CLIP-seq
MIRT1504793	hsa-miR-2110	CLIP-seq
MIRT1504794	hsa-miR-28-5p	CLIP-seq
MIRT1504795	hsa-miR-3120-3p	CLIP-seq
MIRT1504796	hsa-miR-3139	CLIP-seq
MIRT1504797	hsa-miR-3144-5p	CLIP-seq
MIRT1504798	hsa-miR-3150a-3p	CLIP-seq
MIRT1504799	hsa-miR-3173-3p	CLIP-seq
MIRT1504800	hsa-miR-3183	CLIP-seq
MIRT1504801	hsa-miR-3184	CLIP-seq
MIRT1504802	hsa-miR-3191	CLIP-seq
MIRT1504803	hsa-miR-342-3p	CLIP-seq
MIRT1504804	hsa-miR-3612	CLIP-seq
MIRT1504805	hsa-miR-377	CLIP-seq
MIRT1504806	hsa-miR-378g	CLIP-seq
MIRT1504807	hsa-miR-3940-3p	CLIP-seq
MIRT1504808	hsa-miR-3974	CLIP-seq
MIRT1504809	hsa-miR-423-5p	CLIP-seq
MIRT1504810	hsa-miR-4266	CLIP-seq
MIRT1504811	hsa-miR-4270	CLIP-seq
MIRT1504812	hsa-miR-4292	CLIP-seq
MIRT1504813	hsa-miR-4306	CLIP-seq
MIRT1504814	hsa-miR-4419a	CLIP-seq
MIRT1504815	hsa-miR-4420	CLIP-seq
MIRT1504816	hsa-miR-4428	CLIP-seq
MIRT1504817	hsa-miR-4437	CLIP-seq
MIRT1504818	hsa-miR-4441	CLIP-seq
MIRT1504819	hsa-miR-4459	CLIP-seq
MIRT1504820	hsa-miR-4476	CLIP-seq
MIRT1504821	hsa-miR-4510	CLIP-seq
MIRT1504822	hsa-miR-4533	CLIP-seq
MIRT1504823	hsa-miR-4644	CLIP-seq
MIRT1504824	hsa-miR-4652-5p	CLIP-seq
MIRT1504825	hsa-miR-4668-5p	CLIP-seq
MIRT1504826	hsa-miR-4674	CLIP-seq
MIRT1504827	hsa-miR-4695-5p	CLIP-seq
MIRT1504828	hsa-miR-4722-3p	CLIP-seq
MIRT1504829	hsa-miR-4723-3p	CLIP-seq
MIRT1504830	hsa-miR-4728-5p	CLIP-seq
MIRT1504831	hsa-miR-4739	CLIP-seq
MIRT1504832	hsa-miR-4745-3p	CLIP-seq
MIRT1504833	hsa-miR-4747-3p	CLIP-seq
MIRT1504834	hsa-miR-4756-5p	CLIP-seq
MIRT1504835	hsa-miR-493	CLIP-seq
MIRT1504836	hsa-miR-508-5p	CLIP-seq
MIRT1504837	hsa-miR-545	CLIP-seq
MIRT1504838	hsa-miR-548p	CLIP-seq
MIRT1504839	hsa-miR-634	CLIP-seq
MIRT1504840	hsa-miR-650	CLIP-seq
MIRT1504841	hsa-miR-651	CLIP-seq
MIRT1504842	hsa-miR-665	CLIP-seq
MIRT1504843	hsa-miR-708	CLIP-seq
MIRT1504844	hsa-miR-766	CLIP-seq
MIRT1504845	hsa-miR-873	CLIP-seq
MIRT1504788	hsa-miR-1238	CLIP-seq
MIRT1504800	hsa-miR-3183	CLIP-seq
MIRT1504829	hsa-miR-4723-3p	CLIP-seq
MIRT1922504	hsa-miR-4753-3p	CLIP-seq
MIRT1504788	hsa-miR-1238	CLIP-seq
MIRT1504800	hsa-miR-3183	CLIP-seq
MIRT1504829	hsa-miR-4723-3p	CLIP-seq
MIRT1922504	hsa-miR-4753-3p	CLIP-seq
MIRT2151982	hsa-miR-1178	CLIP-seq
MIRT2151983	hsa-miR-1202	CLIP-seq
MIRT2151984	hsa-miR-129-5p	CLIP-seq
MIRT1504800	hsa-miR-3183	CLIP-seq
MIRT2151985	hsa-miR-3664-3p	CLIP-seq
MIRT2151986	hsa-miR-3934	CLIP-seq
MIRT2151987	hsa-miR-3972	CLIP-seq
MIRT2151988	hsa-miR-4423-5p	CLIP-seq
MIRT2151989	hsa-miR-4694-5p	CLIP-seq
MIRT1504829	hsa-miR-4723-3p	CLIP-seq
MIRT2151990	hsa-miR-4755-3p	CLIP-seq
MIRT2151991	hsa-miR-663b	CLIP-seq
MIRT2151992	hsa-miR-767-3p	CLIP-seq
MIRT1504845	hsa-miR-873	CLIP-seq
MIRT2372371	hsa-miR-124	CLIP-seq
MIRT2372372	hsa-miR-1243	CLIP-seq
MIRT2372373	hsa-miR-1254	CLIP-seq
MIRT2372374	hsa-miR-125a-5p	CLIP-seq
MIRT2372375	hsa-miR-125b	CLIP-seq
MIRT2372376	hsa-miR-127-5p	CLIP-seq
MIRT1504792	hsa-miR-185	CLIP-seq
MIRT2372377	hsa-miR-3116	CLIP-seq
MIRT2372378	hsa-miR-3117-5p	CLIP-seq
MIRT2372379	hsa-miR-3169	CLIP-seq
MIRT2372380	hsa-miR-3185	CLIP-seq
MIRT2372381	hsa-miR-3591-3p	CLIP-seq
MIRT2372382	hsa-miR-3611	CLIP-seq
MIRT2372383	hsa-miR-3622a-5p	CLIP-seq
MIRT2372384	hsa-miR-3650	CLIP-seq
MIRT2372385	hsa-miR-3914	CLIP-seq
MIRT2372386	hsa-miR-3915	CLIP-seq
MIRT2372387	hsa-miR-3928	CLIP-seq
MIRT1504808	hsa-miR-3974	CLIP-seq
MIRT2372388	hsa-miR-4254	CLIP-seq
MIRT2372389	hsa-miR-4265	CLIP-seq
MIRT2372390	hsa-miR-4296	CLIP-seq
MIRT1504813	hsa-miR-4306	CLIP-seq
MIRT2372391	hsa-miR-4319	CLIP-seq
MIRT2372392	hsa-miR-4320	CLIP-seq
MIRT2372393	hsa-miR-4322	CLIP-seq
MIRT2372394	hsa-miR-4417	CLIP-seq
MIRT1504814	hsa-miR-4419a	CLIP-seq
MIRT2372395	hsa-miR-4434	CLIP-seq
MIRT2372396	hsa-miR-4436a	CLIP-seq
MIRT2372397	hsa-miR-4446-3p	CLIP-seq
MIRT1504820	hsa-miR-4476	CLIP-seq
MIRT1504821	hsa-miR-4510	CLIP-seq
MIRT2372398	hsa-miR-4515	CLIP-seq
MIRT2372399	hsa-miR-4516	CLIP-seq
MIRT2372400	hsa-miR-4530	CLIP-seq
MIRT2372401	hsa-miR-4640-5p	CLIP-seq
MIRT2372402	hsa-miR-4642	CLIP-seq
MIRT1504823	hsa-miR-4644	CLIP-seq
MIRT2372403	hsa-miR-4700-3p	CLIP-seq
MIRT2372404	hsa-miR-4712-3p	CLIP-seq
MIRT2372405	hsa-miR-4721	CLIP-seq
MIRT2372406	hsa-miR-4726-5p	CLIP-seq
MIRT2372407	hsa-miR-4761-5p	CLIP-seq
MIRT2372408	hsa-miR-4797-5p	CLIP-seq
MIRT2372409	hsa-miR-506	CLIP-seq
MIRT2372410	hsa-miR-513a-5p	CLIP-seq
MIRT2372411	hsa-miR-544b	CLIP-seq
MIRT2372412	hsa-miR-548v	CLIP-seq
MIRT2372413	hsa-miR-564	CLIP-seq
MIRT2372414	hsa-miR-602	CLIP-seq
MIRT2372415	hsa-miR-610	CLIP-seq
MIRT2372416	hsa-miR-625	CLIP-seq
MIRT2372417	hsa-miR-628-5p	CLIP-seq
MIRT2372418	hsa-miR-647	CLIP-seq
MIRT2372419	hsa-miR-664	CLIP-seq
MIRT1504845	hsa-miR-873	CLIP-seq
MIRT2372420	hsa-miR-922	CLIP-seq
MIRT1504797	hsa-miR-3144-5p	CLIP-seq
MIRT2372380	hsa-miR-3185	CLIP-seq
MIRT1504802	hsa-miR-3191	CLIP-seq
MIRT2372382	hsa-miR-3611	CLIP-seq
MIRT2372384	hsa-miR-3650	CLIP-seq
MIRT1504806	hsa-miR-378g	CLIP-seq
MIRT2665400	hsa-miR-4287	CLIP-seq
MIRT1504812	hsa-miR-4292	CLIP-seq
MIRT2665401	hsa-miR-4308	CLIP-seq
MIRT1504817	hsa-miR-4437	CLIP-seq
MIRT2665402	hsa-miR-4469	CLIP-seq
MIRT1504824	hsa-miR-4652-5p	CLIP-seq
MIRT2665403	hsa-miR-4667-5p	CLIP-seq
MIRT1504826	hsa-miR-4674	CLIP-seq
MIRT2665404	hsa-miR-4685-3p	CLIP-seq
MIRT2665405	hsa-miR-4700-5p	CLIP-seq
MIRT1504797	hsa-miR-3144-5p	CLIP-seq
MIRT1504802	hsa-miR-3191	CLIP-seq
MIRT1504806	hsa-miR-378g	CLIP-seq
MIRT2665400	hsa-miR-4287	CLIP-seq
MIRT1504812	hsa-miR-4292	CLIP-seq
MIRT2665401	hsa-miR-4308	CLIP-seq
MIRT1504817	hsa-miR-4437	CLIP-seq
MIRT2665402	hsa-miR-4469	CLIP-seq
MIRT1504824	hsa-miR-4652-5p	CLIP-seq
MIRT2665403	hsa-miR-4667-5p	CLIP-seq
MIRT1504826	hsa-miR-4674	CLIP-seq
MIRT2665404	hsa-miR-4685-3p	CLIP-seq
MIRT2665405	hsa-miR-4700-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	9427755
GO:0045600	Process	Positive regulation of fat cell differentiation	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 616591
• HGNC: 31700
• e!Ensembl: ENSG00000184828

Protein

• UniProt ID: A1YPR0
• Protein name: Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C)
• Protein function: May be a tumor suppressor gene.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	24 → 129	BTB/POZ domain	Domain
  PF00096	zf-C2H2	392 → 414	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	448 → 469	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines. {ECO:0000269|PubMed:9427755}.
• Sequence:

  MANDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFK
  KLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIV
  NVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDP
  QDISCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKAN
  IPDRRPSLSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPP
  PPPPFPNDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKP
  KASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPY
  LCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRG
  RKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPGPSPAKHFLAAPKG
  ALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLA
  GLPGLAGLNHVASMSEANN

• Sequence length: 619