ELF1 (E74 like ETS transcription factor 1)

Gene

• Entrez ID: 1997
• Gene name: E74 like ETS transcription factor 1
• Gene symbol: ELF1
• Synonyms (NCBI Gene): EFTUD1, RIA1
• Chromosome: 13
• Chromosome location: 13q14.11
• Summary: This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing resul

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT044877	hsa-miR-194-5p	CLASH	23622248
MIRT735973	hsa-miR-330-3p	Luciferase reporter assay, Western blotting, RNA-seq, qRT-PCR	34201504
MIRT735976	hsa-miR-450b-5p	Luciferase reporter assay, Western blotting, RNA-seq, qRT-PCR	34201504
MIRT959834	hsa-miR-1	CLIP-seq
MIRT959835	hsa-miR-186	CLIP-seq
MIRT959836	hsa-miR-206	CLIP-seq
MIRT959837	hsa-miR-216a	CLIP-seq
MIRT959838	hsa-miR-297	CLIP-seq
MIRT959839	hsa-miR-3074-5p	CLIP-seq
MIRT959840	hsa-miR-3149	CLIP-seq
MIRT959841	hsa-miR-337-3p	CLIP-seq
MIRT959842	hsa-miR-3647-3p	CLIP-seq
MIRT959843	hsa-miR-3673	CLIP-seq
MIRT959844	hsa-miR-3686	CLIP-seq
MIRT959845	hsa-miR-3691-3p	CLIP-seq
MIRT959846	hsa-miR-371-5p	CLIP-seq
MIRT959847	hsa-miR-371b-5p	CLIP-seq
MIRT959848	hsa-miR-376a	CLIP-seq
MIRT959849	hsa-miR-376b	CLIP-seq
MIRT959850	hsa-miR-3941	CLIP-seq
MIRT959851	hsa-miR-3942-3p	CLIP-seq
MIRT959852	hsa-miR-410	CLIP-seq
MIRT959853	hsa-miR-4275	CLIP-seq
MIRT959854	hsa-miR-4280	CLIP-seq
MIRT959855	hsa-miR-4297	CLIP-seq
MIRT959856	hsa-miR-4423-5p	CLIP-seq
MIRT959857	hsa-miR-448	CLIP-seq
MIRT959858	hsa-miR-466	CLIP-seq
MIRT959859	hsa-miR-4672	CLIP-seq
MIRT959860	hsa-miR-4699-3p	CLIP-seq
MIRT959861	hsa-miR-4704-3p	CLIP-seq
MIRT959862	hsa-miR-4731-3p	CLIP-seq
MIRT959863	hsa-miR-4742-3p	CLIP-seq
MIRT959864	hsa-miR-4801	CLIP-seq
MIRT959865	hsa-miR-495	CLIP-seq
MIRT959866	hsa-miR-513a-3p	CLIP-seq
MIRT959867	hsa-miR-548c-3p	CLIP-seq
MIRT959868	hsa-miR-579	CLIP-seq
MIRT959869	hsa-miR-613	CLIP-seq
MIRT959870	hsa-miR-622	CLIP-seq
MIRT959871	hsa-miR-1179	CLIP-seq
MIRT959872	hsa-miR-1226	CLIP-seq
MIRT959873	hsa-miR-1261	CLIP-seq
MIRT959874	hsa-miR-1291	CLIP-seq
MIRT959875	hsa-miR-130a	CLIP-seq
MIRT959876	hsa-miR-130b	CLIP-seq
MIRT959877	hsa-miR-142-5p	CLIP-seq
MIRT959835	hsa-miR-186	CLIP-seq
MIRT959878	hsa-miR-205	CLIP-seq
MIRT959879	hsa-miR-2054	CLIP-seq
MIRT959838	hsa-miR-297	CLIP-seq
MIRT959880	hsa-miR-301a	CLIP-seq
MIRT959881	hsa-miR-301b	CLIP-seq
MIRT959882	hsa-miR-3065-3p	CLIP-seq
MIRT959883	hsa-miR-3130-3p	CLIP-seq
MIRT959884	hsa-miR-3140-3p	CLIP-seq
MIRT959840	hsa-miR-3149	CLIP-seq
MIRT959885	hsa-miR-3157-5p	CLIP-seq
MIRT959886	hsa-miR-3160-5p	CLIP-seq
MIRT959887	hsa-miR-3168	CLIP-seq
MIRT959888	hsa-miR-3201	CLIP-seq
MIRT959889	hsa-miR-323-3p	CLIP-seq
MIRT959890	hsa-miR-323b-3p	CLIP-seq
MIRT959891	hsa-miR-328	CLIP-seq
MIRT959892	hsa-miR-331-5p	CLIP-seq
MIRT959893	hsa-miR-340	CLIP-seq
MIRT959894	hsa-miR-3607-3p	CLIP-seq
MIRT959842	hsa-miR-3647-3p	CLIP-seq
MIRT959895	hsa-miR-3653	CLIP-seq
MIRT959896	hsa-miR-3658	CLIP-seq
MIRT959897	hsa-miR-3662	CLIP-seq
MIRT959898	hsa-miR-3664-5p	CLIP-seq
MIRT959899	hsa-miR-3666	CLIP-seq
MIRT959900	hsa-miR-3684	CLIP-seq
MIRT959844	hsa-miR-3686	CLIP-seq
MIRT959845	hsa-miR-3691-3p	CLIP-seq
MIRT959848	hsa-miR-376a	CLIP-seq
MIRT959849	hsa-miR-376b	CLIP-seq
MIRT959851	hsa-miR-3942-3p	CLIP-seq
MIRT959853	hsa-miR-4275	CLIP-seq
MIRT959854	hsa-miR-4280	CLIP-seq
MIRT959901	hsa-miR-4295	CLIP-seq
MIRT959902	hsa-miR-4326	CLIP-seq
MIRT959903	hsa-miR-4422	CLIP-seq
MIRT959857	hsa-miR-448	CLIP-seq
MIRT959904	hsa-miR-4517	CLIP-seq
MIRT959905	hsa-miR-454	CLIP-seq
MIRT959906	hsa-miR-4639-3p	CLIP-seq
MIRT959907	hsa-miR-4671-3p	CLIP-seq
MIRT959908	hsa-miR-4678	CLIP-seq
MIRT959909	hsa-miR-4691-3p	CLIP-seq
MIRT959860	hsa-miR-4699-3p	CLIP-seq
MIRT959861	hsa-miR-4704-3p	CLIP-seq
MIRT959862	hsa-miR-4731-3p	CLIP-seq
MIRT959910	hsa-miR-4766-3p	CLIP-seq
MIRT959911	hsa-miR-4791	CLIP-seq
MIRT959912	hsa-miR-4793-3p	CLIP-seq
MIRT959864	hsa-miR-4801	CLIP-seq
MIRT959913	hsa-miR-494	CLIP-seq
MIRT959865	hsa-miR-495	CLIP-seq
MIRT959914	hsa-miR-510	CLIP-seq
MIRT959915	hsa-miR-512-5p	CLIP-seq
MIRT959916	hsa-miR-548a-5p	CLIP-seq
MIRT959917	hsa-miR-548ab	CLIP-seq
MIRT959918	hsa-miR-548ac	CLIP-seq
MIRT959919	hsa-miR-548ae	CLIP-seq
MIRT959920	hsa-miR-548aj	CLIP-seq
MIRT959921	hsa-miR-548ak	CLIP-seq
MIRT959922	hsa-miR-548am	CLIP-seq
MIRT959923	hsa-miR-548b-5p	CLIP-seq
MIRT959924	hsa-miR-548c-5p	CLIP-seq
MIRT959925	hsa-miR-548d-3p	CLIP-seq
MIRT959926	hsa-miR-548d-5p	CLIP-seq
MIRT959927	hsa-miR-548h	CLIP-seq
MIRT959928	hsa-miR-548i	CLIP-seq
MIRT959929	hsa-miR-548j	CLIP-seq
MIRT959930	hsa-miR-548n	CLIP-seq
MIRT959931	hsa-miR-548w	CLIP-seq
MIRT959932	hsa-miR-548x	CLIP-seq
MIRT959933	hsa-miR-548y	CLIP-seq
MIRT959934	hsa-miR-548z	CLIP-seq
MIRT959935	hsa-miR-554	CLIP-seq
MIRT959936	hsa-miR-559	CLIP-seq
MIRT959937	hsa-miR-570	CLIP-seq
MIRT959938	hsa-miR-578	CLIP-seq
MIRT959868	hsa-miR-579	CLIP-seq
MIRT959939	hsa-miR-582-5p	CLIP-seq
MIRT959870	hsa-miR-622	CLIP-seq
MIRT959940	hsa-miR-634	CLIP-seq
MIRT959941	hsa-miR-640	CLIP-seq
MIRT959942	hsa-miR-656	CLIP-seq
MIRT1984325	hsa-miR-1236	CLIP-seq
MIRT959873	hsa-miR-1261	CLIP-seq
MIRT1984326	hsa-miR-2276	CLIP-seq
MIRT1984327	hsa-miR-3125	CLIP-seq
MIRT959888	hsa-miR-3201	CLIP-seq
MIRT959889	hsa-miR-323-3p	CLIP-seq
MIRT959890	hsa-miR-323b-3p	CLIP-seq
MIRT959842	hsa-miR-3647-3p	CLIP-seq
MIRT1984328	hsa-miR-376c	CLIP-seq
MIRT1984329	hsa-miR-3916	CLIP-seq
MIRT1984330	hsa-miR-3928	CLIP-seq
MIRT959851	hsa-miR-3942-3p	CLIP-seq
MIRT1984331	hsa-miR-4282	CLIP-seq
MIRT1984332	hsa-miR-4460	CLIP-seq
MIRT959857	hsa-miR-448	CLIP-seq
MIRT1984333	hsa-miR-4496	CLIP-seq
MIRT959861	hsa-miR-4704-3p	CLIP-seq
MIRT1984334	hsa-miR-4712-3p	CLIP-seq
MIRT1984335	hsa-miR-4727-3p	CLIP-seq
MIRT1984336	hsa-miR-4772-3p	CLIP-seq
MIRT959911	hsa-miR-4791	CLIP-seq
MIRT1984337	hsa-miR-489	CLIP-seq
MIRT1984338	hsa-miR-490-3p	CLIP-seq
MIRT959866	hsa-miR-513a-3p	CLIP-seq
MIRT959916	hsa-miR-548a-5p	CLIP-seq
MIRT959917	hsa-miR-548ab	CLIP-seq
MIRT959921	hsa-miR-548ak	CLIP-seq
MIRT959923	hsa-miR-548b-5p	CLIP-seq
MIRT959924	hsa-miR-548c-5p	CLIP-seq
MIRT959926	hsa-miR-548d-5p	CLIP-seq
MIRT959927	hsa-miR-548h	CLIP-seq
MIRT959928	hsa-miR-548i	CLIP-seq
MIRT959929	hsa-miR-548j	CLIP-seq
MIRT959930	hsa-miR-548n	CLIP-seq
MIRT959931	hsa-miR-548w	CLIP-seq
MIRT959933	hsa-miR-548y	CLIP-seq
MIRT959935	hsa-miR-554	CLIP-seq
MIRT959936	hsa-miR-559	CLIP-seq
MIRT959868	hsa-miR-579	CLIP-seq
MIRT1984339	hsa-miR-583	CLIP-seq
MIRT1984340	hsa-miR-600	CLIP-seq
MIRT959870	hsa-miR-622	CLIP-seq
MIRT1984341	hsa-miR-649	CLIP-seq
MIRT959835	hsa-miR-186	CLIP-seq
MIRT959837	hsa-miR-216a	CLIP-seq
MIRT959839	hsa-miR-3074-5p	CLIP-seq
MIRT959885	hsa-miR-3157-5p	CLIP-seq
MIRT959841	hsa-miR-337-3p	CLIP-seq
MIRT2219455	hsa-miR-33a	CLIP-seq
MIRT2219456	hsa-miR-33b	CLIP-seq
MIRT959842	hsa-miR-3647-3p	CLIP-seq
MIRT959897	hsa-miR-3662	CLIP-seq
MIRT959846	hsa-miR-371-5p	CLIP-seq
MIRT959847	hsa-miR-371b-5p	CLIP-seq
MIRT959848	hsa-miR-376a	CLIP-seq
MIRT959849	hsa-miR-376b	CLIP-seq
MIRT959852	hsa-miR-410	CLIP-seq
MIRT959854	hsa-miR-4280	CLIP-seq
MIRT959855	hsa-miR-4297	CLIP-seq
MIRT959856	hsa-miR-4423-5p	CLIP-seq
MIRT959909	hsa-miR-4691-3p	CLIP-seq
MIRT959862	hsa-miR-4731-3p	CLIP-seq
MIRT959864	hsa-miR-4801	CLIP-seq
MIRT2219457	hsa-miR-488	CLIP-seq
MIRT959913	hsa-miR-494	CLIP-seq
MIRT959914	hsa-miR-510	CLIP-seq
MIRT959915	hsa-miR-512-5p	CLIP-seq
MIRT959866	hsa-miR-513a-3p	CLIP-seq
MIRT959867	hsa-miR-548c-3p	CLIP-seq
MIRT1984339	hsa-miR-583	CLIP-seq
MIRT959872	hsa-miR-1226	CLIP-seq
MIRT959882	hsa-miR-3065-3p	CLIP-seq
MIRT959885	hsa-miR-3157-5p	CLIP-seq
MIRT959889	hsa-miR-323-3p	CLIP-seq
MIRT959909	hsa-miR-4691-3p	CLIP-seq
MIRT959860	hsa-miR-4699-3p	CLIP-seq
MIRT959913	hsa-miR-494	CLIP-seq
MIRT959939	hsa-miR-582-5p	CLIP-seq
MIRT959940	hsa-miR-634	CLIP-seq
MIRT959838	hsa-miR-297	CLIP-seq
MIRT959840	hsa-miR-3149	CLIP-seq
MIRT959867	hsa-miR-548c-3p	CLIP-seq
MIRT2465204	hsa-miR-3152-5p	CLIP-seq
MIRT959895	hsa-miR-3653	CLIP-seq
MIRT959896	hsa-miR-3658	CLIP-seq
MIRT2465205	hsa-miR-4774-3p	CLIP-seq
MIRT959834	hsa-miR-1	CLIP-seq
MIRT2522724	hsa-miR-1238	CLIP-seq
MIRT2522725	hsa-miR-129-5p	CLIP-seq
MIRT959835	hsa-miR-186	CLIP-seq
MIRT959836	hsa-miR-206	CLIP-seq
MIRT959839	hsa-miR-3074-5p	CLIP-seq
MIRT2522726	hsa-miR-3163	CLIP-seq
MIRT959889	hsa-miR-323-3p	CLIP-seq
MIRT959841	hsa-miR-337-3p	CLIP-seq
MIRT2219455	hsa-miR-33a	CLIP-seq
MIRT2219456	hsa-miR-33b	CLIP-seq
MIRT959842	hsa-miR-3647-3p	CLIP-seq
MIRT959843	hsa-miR-3673	CLIP-seq
MIRT959844	hsa-miR-3686	CLIP-seq
MIRT959850	hsa-miR-3941	CLIP-seq
MIRT959851	hsa-miR-3942-3p	CLIP-seq
MIRT959852	hsa-miR-410	CLIP-seq
MIRT959853	hsa-miR-4275	CLIP-seq
MIRT1984331	hsa-miR-4282	CLIP-seq
MIRT959855	hsa-miR-4297	CLIP-seq
MIRT2522727	hsa-miR-4311	CLIP-seq
MIRT959903	hsa-miR-4422	CLIP-seq
MIRT959856	hsa-miR-4423-5p	CLIP-seq
MIRT2522728	hsa-miR-4464	CLIP-seq
MIRT2522729	hsa-miR-4469	CLIP-seq
MIRT2522730	hsa-miR-4495	CLIP-seq
MIRT959858	hsa-miR-466	CLIP-seq
MIRT959859	hsa-miR-4672	CLIP-seq
MIRT2522731	hsa-miR-4691-5p	CLIP-seq
MIRT2522732	hsa-miR-4698	CLIP-seq
MIRT959860	hsa-miR-4699-3p	CLIP-seq
MIRT959862	hsa-miR-4731-3p	CLIP-seq
MIRT959863	hsa-miR-4742-3p	CLIP-seq
MIRT2522733	hsa-miR-4748	CLIP-seq
MIRT2522734	hsa-miR-4760-5p	CLIP-seq
MIRT2522735	hsa-miR-4764-3p	CLIP-seq
MIRT2522736	hsa-miR-4775	CLIP-seq
MIRT959864	hsa-miR-4801	CLIP-seq
MIRT2219457	hsa-miR-488	CLIP-seq
MIRT959913	hsa-miR-494	CLIP-seq
MIRT959865	hsa-miR-495	CLIP-seq
MIRT2522737	hsa-miR-507	CLIP-seq
MIRT959866	hsa-miR-513a-3p	CLIP-seq
MIRT2522738	hsa-miR-520d-5p	CLIP-seq
MIRT2522739	hsa-miR-524-5p	CLIP-seq
MIRT959916	hsa-miR-548a-5p	CLIP-seq
MIRT959917	hsa-miR-548ab	CLIP-seq
MIRT959918	hsa-miR-548ac	CLIP-seq
MIRT959919	hsa-miR-548ae	CLIP-seq
MIRT959920	hsa-miR-548aj	CLIP-seq
MIRT959921	hsa-miR-548ak	CLIP-seq
MIRT959922	hsa-miR-548am	CLIP-seq
MIRT959923	hsa-miR-548b-5p	CLIP-seq
MIRT959924	hsa-miR-548c-5p	CLIP-seq
MIRT959925	hsa-miR-548d-3p	CLIP-seq
MIRT959926	hsa-miR-548d-5p	CLIP-seq
MIRT959927	hsa-miR-548h	CLIP-seq
MIRT959928	hsa-miR-548i	CLIP-seq
MIRT959929	hsa-miR-548j	CLIP-seq
MIRT959930	hsa-miR-548n	CLIP-seq
MIRT959931	hsa-miR-548w	CLIP-seq
MIRT959932	hsa-miR-548x	CLIP-seq
MIRT959933	hsa-miR-548y	CLIP-seq
MIRT959934	hsa-miR-548z	CLIP-seq
MIRT2522740	hsa-miR-557	CLIP-seq
MIRT959936	hsa-miR-559	CLIP-seq
MIRT2522741	hsa-miR-577	CLIP-seq
MIRT959868	hsa-miR-579	CLIP-seq
MIRT959939	hsa-miR-582-5p	CLIP-seq
MIRT2522742	hsa-miR-590-3p	CLIP-seq
MIRT959869	hsa-miR-613	CLIP-seq
MIRT2522743	hsa-miR-618	CLIP-seq
MIRT2522724	hsa-miR-1238	CLIP-seq
MIRT2522727	hsa-miR-4311	CLIP-seq
MIRT959903	hsa-miR-4422	CLIP-seq
MIRT2522729	hsa-miR-4469	CLIP-seq
MIRT2522731	hsa-miR-4691-5p	CLIP-seq
MIRT2522732	hsa-miR-4698	CLIP-seq
MIRT2522734	hsa-miR-4760-5p	CLIP-seq
MIRT2522735	hsa-miR-4764-3p	CLIP-seq
MIRT2522736	hsa-miR-4775	CLIP-seq
MIRT959913	hsa-miR-494	CLIP-seq
MIRT959865	hsa-miR-495	CLIP-seq
MIRT2522741	hsa-miR-577	CLIP-seq
MIRT2522742	hsa-miR-590-3p	CLIP-seq
MIRT2522743	hsa-miR-618	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
RB1	Unknown	7702750

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	8756667
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	8756667
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0001817	Process	Regulation of cytokine production	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IDA	14970218
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	10207087, 10976766, 18692240, 19674970, 28514442, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IC	14970218
GO:0005634	Component	Nucleus	IDA	19674970
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0030154	Process	Cell differentiation	IBA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	19674970
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	NAS	1527846
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	8756667, 14970218, 19674970
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0050860	Process	Negative regulation of T cell receptor signaling pathway	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 189973
• HGNC: 3316
• e!Ensembl: ENSG00000120690

Protein

• UniProt ID: P32519
• Protein name: ETS-related transcription factor Elf-1 (E74-like factor 1)
• Protein function: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269|Pu
• PDB: 8BZM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12310	Elf-1_N	2 → 111	Transcription factor protein N terminal	Family
  PF00178	Ets	209 → 290	Ets-domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in hear
• Sequence:

  MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDM
  ITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRI
  NNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKT
  KPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKL
  VDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYIN
  DEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVE
  VAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRT
  IQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVL
  KENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPR
  SSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSN
  GFTSQVAMKQNELLEPNSF

• Sequence length: 619

Pathways

Reactome:

RUNX1 regulates transcription of genes involved in BCR signaling
RUNX1 regulates transcription of genes involved in interleukin signaling