ELF1 (E74 like ETS transcription factor 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1997 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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E74 like ETS transcription factor 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ELF1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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EFTUD1, RIA1 |
Chromosome
Chromosome number
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13 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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13q14.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing resul |
miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | P32519 | |||||||||||||||
Protein name | ETS-related transcription factor Elf-1 (E74-like factor 1) | |||||||||||||||
Protein function | Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269|Pu | |||||||||||||||
PDB | 8BZM | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in hear | |||||||||||||||
Sequence |
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Sequence length | 619 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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