EIF4B (eukaryotic translation initiation factor 4B)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1975 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Eukaryotic translation initiation factor 4B |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EIF4B |
Synonyms (NCBI Gene)
Gene synonyms aliases
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EIF-4B, PRO1843 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q13.13 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P23588 | ||||||||||
Protein name | Eukaryotic translation initiation factor 4B (eIF-4B) | ||||||||||
Protein function | Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity | ||||||||||
PDB | 1WI8 , 2J76 , 6FEC | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 611 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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