Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	197358
Gene name	NLR family CARD domain containing 3
Gene symbol	NLRC3
Synonyms (NCBI Gene)	CLR16.2NOD3
Chromosome	16
Chromosome location	16p13.3
Summary	This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption o

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miRTarBase ID	miRNA	Experiments	Reference
MIRT701391	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT701390	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT701389	hsa-miR-4293	HITS-CLIP	23313552
MIRT701388	hsa-miR-3675-3p	HITS-CLIP	23313552
MIRT701387	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT661797	hsa-miR-3929	HITS-CLIP	23824327
MIRT661796	hsa-miR-4419b	HITS-CLIP	23824327
MIRT661795	hsa-miR-4478	HITS-CLIP	23824327
MIRT661794	hsa-miR-4717-3p	HITS-CLIP	23824327
MIRT661793	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT661792	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT661791	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT661790	hsa-miR-8089	HITS-CLIP	23824327
MIRT661789	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT661788	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT661787	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT661786	hsa-miR-3175	HITS-CLIP	23824327
MIRT661785	hsa-miR-1343-5p	HITS-CLIP	23824327
MIRT661784	hsa-miR-939-5p	HITS-CLIP	23824327
MIRT661783	hsa-miR-6825-5p	HITS-CLIP	23824327
MIRT661782	hsa-miR-3150a-3p	HITS-CLIP	23824327
MIRT661781	hsa-miR-6763-5p	HITS-CLIP	23824327
MIRT661780	hsa-miR-665	HITS-CLIP	23824327
MIRT701387	hsa-miR-4684-5p	PAR-CLIP	27292025
MIRT701390	hsa-miR-6771-3p	PAR-CLIP	27292025
MIRT701391	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT701390	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT701389	hsa-miR-4293	HITS-CLIP	23313552
MIRT701388	hsa-miR-3675-3p	HITS-CLIP	23313552
MIRT701387	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT661797	hsa-miR-3929	HITS-CLIP	23824327
MIRT661796	hsa-miR-4419b	HITS-CLIP	23824327
MIRT661795	hsa-miR-4478	HITS-CLIP	23824327
MIRT661794	hsa-miR-4717-3p	HITS-CLIP	23824327
MIRT661793	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT661792	hsa-miR-4667-5p	HITS-CLIP	23824327
MIRT661791	hsa-miR-4700-5p	HITS-CLIP	23824327
MIRT661790	hsa-miR-8089	HITS-CLIP	23824327
MIRT661789	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT661788	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT661787	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT661786	hsa-miR-3175	HITS-CLIP	23824327
MIRT661785	hsa-miR-1343-5p	HITS-CLIP	23824327
MIRT661784	hsa-miR-939-5p	HITS-CLIP	23824327
MIRT661783	hsa-miR-6825-5p	HITS-CLIP	23824327
MIRT661782	hsa-miR-3150a-3p	HITS-CLIP	23824327
MIRT661781	hsa-miR-6763-5p	HITS-CLIP	23824327
MIRT661780	hsa-miR-665	HITS-CLIP	23824327
MIRT1187145	hsa-miR-1227	CLIP-seq
MIRT1187146	hsa-miR-1228	CLIP-seq
MIRT1187147	hsa-miR-1273	CLIP-seq
MIRT1187148	hsa-miR-1273c	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT1187150	hsa-miR-186	CLIP-seq
MIRT1187151	hsa-miR-24	CLIP-seq
MIRT1187152	hsa-miR-3120-5p	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT1187154	hsa-miR-3133	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187156	hsa-miR-3180-5p	CLIP-seq
MIRT1187157	hsa-miR-3202	CLIP-seq
MIRT1187158	hsa-miR-323-5p	CLIP-seq
MIRT1187159	hsa-miR-335	CLIP-seq
MIRT1187160	hsa-miR-342-3p	CLIP-seq
MIRT1187161	hsa-miR-3613-3p	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT1187165	hsa-miR-371-5p	CLIP-seq
MIRT1187166	hsa-miR-371b-5p	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT1187168	hsa-miR-4252	CLIP-seq
MIRT1187169	hsa-miR-4284	CLIP-seq
MIRT1187170	hsa-miR-4300	CLIP-seq
MIRT1187171	hsa-miR-4424	CLIP-seq
MIRT1187172	hsa-miR-4433	CLIP-seq
MIRT1187173	hsa-miR-4455	CLIP-seq
MIRT1187174	hsa-miR-4459	CLIP-seq
MIRT1187175	hsa-miR-4466	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT1187177	hsa-miR-4486	CLIP-seq
MIRT1187178	hsa-miR-4509	CLIP-seq
MIRT1187179	hsa-miR-4533	CLIP-seq
MIRT1187180	hsa-miR-4633-3p	CLIP-seq
MIRT1187181	hsa-miR-4649-5p	CLIP-seq
MIRT1187182	hsa-miR-4653-3p	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT1187184	hsa-miR-4768-3p	CLIP-seq
MIRT1187185	hsa-miR-4778-5p	CLIP-seq
MIRT1187186	hsa-miR-4793-3p	CLIP-seq
MIRT1187187	hsa-miR-508-5p	CLIP-seq
MIRT1187188	hsa-miR-520a-5p	CLIP-seq
MIRT1187189	hsa-miR-525-5p	CLIP-seq
MIRT1187190	hsa-miR-548a-3p	CLIP-seq
MIRT1187191	hsa-miR-548e	CLIP-seq
MIRT1187192	hsa-miR-548f	CLIP-seq
MIRT1187193	hsa-miR-548m	CLIP-seq
MIRT1187194	hsa-miR-548u	CLIP-seq
MIRT1187195	hsa-miR-609	CLIP-seq
MIRT1187196	hsa-miR-610	CLIP-seq
MIRT1187197	hsa-miR-661	CLIP-seq
MIRT1187198	hsa-miR-675	CLIP-seq
MIRT1187199	hsa-miR-764	CLIP-seq
MIRT1187200	hsa-miR-766	CLIP-seq
MIRT1187201	hsa-miR-876-3p	CLIP-seq
MIRT1187202	hsa-miR-920	CLIP-seq
MIRT1187145	hsa-miR-1227	CLIP-seq
MIRT2054203	hsa-miR-1254	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT1187150	hsa-miR-186	CLIP-seq
MIRT2054204	hsa-miR-199a-5p	CLIP-seq
MIRT2054205	hsa-miR-199b-5p	CLIP-seq
MIRT2054206	hsa-miR-3116	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT1187154	hsa-miR-3133	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT2054207	hsa-miR-3619-3p	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT2054208	hsa-miR-3690	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT2054209	hsa-miR-3938	CLIP-seq
MIRT1187171	hsa-miR-4424	CLIP-seq
MIRT1187172	hsa-miR-4433	CLIP-seq
MIRT1187174	hsa-miR-4459	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT2054210	hsa-miR-4640-3p	CLIP-seq
MIRT1187182	hsa-miR-4653-3p	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT2054211	hsa-miR-4742-3p	CLIP-seq
MIRT1187184	hsa-miR-4768-3p	CLIP-seq
MIRT2054212	hsa-miR-4776-5p	CLIP-seq
MIRT1187187	hsa-miR-508-5p	CLIP-seq
MIRT2054213	hsa-miR-515-5p	CLIP-seq
MIRT2054214	hsa-miR-550a	CLIP-seq
MIRT2054215	hsa-miR-630	CLIP-seq
MIRT1187197	hsa-miR-661	CLIP-seq
MIRT2054216	hsa-miR-663b	CLIP-seq
MIRT1187145	hsa-miR-1227	CLIP-seq
MIRT1187146	hsa-miR-1228	CLIP-seq
MIRT2283365	hsa-miR-1253	CLIP-seq
MIRT1187147	hsa-miR-1273	CLIP-seq
MIRT1187148	hsa-miR-1273c	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT2283366	hsa-miR-139-5p	CLIP-seq
MIRT2283367	hsa-miR-1827	CLIP-seq
MIRT2283368	hsa-miR-1908	CLIP-seq
MIRT2283369	hsa-miR-1909	CLIP-seq
MIRT1187151	hsa-miR-24	CLIP-seq
MIRT2283370	hsa-miR-28-5p	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT2283371	hsa-miR-3139	CLIP-seq
MIRT2283372	hsa-miR-3160-3p	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187158	hsa-miR-323-5p	CLIP-seq
MIRT1187159	hsa-miR-335	CLIP-seq
MIRT1187160	hsa-miR-342-3p	CLIP-seq
MIRT2283373	hsa-miR-34b	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT2283374	hsa-miR-3656	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT1187168	hsa-miR-4252	CLIP-seq
MIRT2283375	hsa-miR-4270	CLIP-seq
MIRT1187169	hsa-miR-4284	CLIP-seq
MIRT1187170	hsa-miR-4300	CLIP-seq
MIRT1187171	hsa-miR-4424	CLIP-seq
MIRT1187172	hsa-miR-4433	CLIP-seq
MIRT2283376	hsa-miR-4441	CLIP-seq
MIRT1187173	hsa-miR-4455	CLIP-seq
MIRT1187174	hsa-miR-4459	CLIP-seq
MIRT1187175	hsa-miR-4466	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT1187177	hsa-miR-4486	CLIP-seq
MIRT2283377	hsa-miR-4487	CLIP-seq
MIRT1187181	hsa-miR-4649-5p	CLIP-seq
MIRT1187182	hsa-miR-4653-3p	CLIP-seq
MIRT2283378	hsa-miR-4659a-3p	CLIP-seq
MIRT2283379	hsa-miR-4659b-3p	CLIP-seq
MIRT2283380	hsa-miR-4712-5p	CLIP-seq
MIRT2283381	hsa-miR-4722-5p	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT1187184	hsa-miR-4768-3p	CLIP-seq
MIRT2283382	hsa-miR-4778-3p	CLIP-seq
MIRT1187185	hsa-miR-4778-5p	CLIP-seq
MIRT1187186	hsa-miR-4793-3p	CLIP-seq
MIRT1187187	hsa-miR-508-5p	CLIP-seq
MIRT2283383	hsa-miR-526b	CLIP-seq
MIRT2283384	hsa-miR-544b	CLIP-seq
MIRT1187194	hsa-miR-548u	CLIP-seq
MIRT2054214	hsa-miR-550a	CLIP-seq
MIRT2283385	hsa-miR-558	CLIP-seq
MIRT2283386	hsa-miR-580	CLIP-seq
MIRT2283387	hsa-miR-603	CLIP-seq
MIRT2283388	hsa-miR-606	CLIP-seq
MIRT1187195	hsa-miR-609	CLIP-seq
MIRT2283389	hsa-miR-658	CLIP-seq
MIRT1187197	hsa-miR-661	CLIP-seq
MIRT2283390	hsa-miR-663	CLIP-seq
MIRT1187198	hsa-miR-675	CLIP-seq
MIRT2283391	hsa-miR-708	CLIP-seq
MIRT1187200	hsa-miR-766	CLIP-seq
MIRT2283392	hsa-miR-770-5p	CLIP-seq
MIRT1187201	hsa-miR-876-3p	CLIP-seq
MIRT2283393	hsa-miR-890	CLIP-seq
MIRT1187202	hsa-miR-920	CLIP-seq
MIRT2283394	hsa-miR-940	CLIP-seq
MIRT2439011	hsa-miR-149	CLIP-seq
MIRT2439012	hsa-miR-3650	CLIP-seq
MIRT2439013	hsa-miR-4299	CLIP-seq
MIRT2439014	hsa-miR-4456	CLIP-seq
MIRT2439015	hsa-miR-548q	CLIP-seq
MIRT2054214	hsa-miR-550a	CLIP-seq
MIRT2439016	hsa-miR-760	CLIP-seq
MIRT2455247	hsa-miR-103a	CLIP-seq
MIRT2455248	hsa-miR-107	CLIP-seq
MIRT2455249	hsa-miR-1184	CLIP-seq
MIRT1187146	hsa-miR-1228	CLIP-seq
MIRT2455250	hsa-miR-1283	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT2283368	hsa-miR-1908	CLIP-seq
MIRT2455251	hsa-miR-1976	CLIP-seq
MIRT2283370	hsa-miR-28-5p	CLIP-seq
MIRT2455252	hsa-miR-298	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT2283371	hsa-miR-3139	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187158	hsa-miR-323-5p	CLIP-seq
MIRT1187161	hsa-miR-3613-3p	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT2455253	hsa-miR-3622b-5p	CLIP-seq
MIRT2283374	hsa-miR-3656	CLIP-seq
MIRT2455254	hsa-miR-3670	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT1187165	hsa-miR-371-5p	CLIP-seq
MIRT1187166	hsa-miR-371b-5p	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT2455255	hsa-miR-4253	CLIP-seq
MIRT1187172	hsa-miR-4433	CLIP-seq
MIRT1187173	hsa-miR-4455	CLIP-seq
MIRT1187174	hsa-miR-4459	CLIP-seq
MIRT1187175	hsa-miR-4466	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT1187182	hsa-miR-4653-3p	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT1187184	hsa-miR-4768-3p	CLIP-seq
MIRT2455256	hsa-miR-483-3p	CLIP-seq
MIRT2455257	hsa-miR-495	CLIP-seq
MIRT1187190	hsa-miR-548a-3p	CLIP-seq
MIRT1187191	hsa-miR-548e	CLIP-seq
MIRT1187192	hsa-miR-548f	CLIP-seq
MIRT1187195	hsa-miR-609	CLIP-seq
MIRT2283390	hsa-miR-663	CLIP-seq
MIRT1187198	hsa-miR-675	CLIP-seq
MIRT2283391	hsa-miR-708	CLIP-seq
MIRT1187201	hsa-miR-876-3p	CLIP-seq
MIRT2455258	hsa-miR-922	CLIP-seq
MIRT1187146	hsa-miR-1228	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT1187173	hsa-miR-4455	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT1187195	hsa-miR-609	CLIP-seq
MIRT1187146	hsa-miR-1228	CLIP-seq
MIRT1187147	hsa-miR-1273	CLIP-seq
MIRT1187148	hsa-miR-1273c	CLIP-seq
MIRT2455250	hsa-miR-1283	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT2439011	hsa-miR-149	CLIP-seq
MIRT1187150	hsa-miR-186	CLIP-seq
MIRT1187152	hsa-miR-3120-5p	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT1187154	hsa-miR-3133	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187158	hsa-miR-323-5p	CLIP-seq
MIRT1187159	hsa-miR-335	CLIP-seq
MIRT1187161	hsa-miR-3613-3p	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT2439012	hsa-miR-3650	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT1187165	hsa-miR-371-5p	CLIP-seq
MIRT1187166	hsa-miR-371b-5p	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT1187168	hsa-miR-4252	CLIP-seq
MIRT2439013	hsa-miR-4299	CLIP-seq
MIRT1187171	hsa-miR-4424	CLIP-seq
MIRT1187172	hsa-miR-4433	CLIP-seq
MIRT1187173	hsa-miR-4455	CLIP-seq
MIRT2439014	hsa-miR-4456	CLIP-seq
MIRT1187174	hsa-miR-4459	CLIP-seq
MIRT1187175	hsa-miR-4466	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT1187177	hsa-miR-4486	CLIP-seq
MIRT1187181	hsa-miR-4649-5p	CLIP-seq
MIRT1187182	hsa-miR-4653-3p	CLIP-seq
MIRT2283380	hsa-miR-4712-5p	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT1187184	hsa-miR-4768-3p	CLIP-seq
MIRT1187185	hsa-miR-4778-5p	CLIP-seq
MIRT1187186	hsa-miR-4793-3p	CLIP-seq
MIRT2455257	hsa-miR-495	CLIP-seq
MIRT1187187	hsa-miR-508-5p	CLIP-seq
MIRT1187190	hsa-miR-548a-3p	CLIP-seq
MIRT1187191	hsa-miR-548e	CLIP-seq
MIRT1187192	hsa-miR-548f	CLIP-seq
MIRT2439015	hsa-miR-548q	CLIP-seq
MIRT2054214	hsa-miR-550a	CLIP-seq
MIRT1187195	hsa-miR-609	CLIP-seq
MIRT1187197	hsa-miR-661	CLIP-seq
MIRT1187198	hsa-miR-675	CLIP-seq
MIRT2439016	hsa-miR-760	CLIP-seq
MIRT1187200	hsa-miR-766	CLIP-seq
MIRT2283392	hsa-miR-770-5p	CLIP-seq
MIRT1187201	hsa-miR-876-3p	CLIP-seq
MIRT1187146	hsa-miR-1228	CLIP-seq
MIRT1187147	hsa-miR-1273	CLIP-seq
MIRT1187148	hsa-miR-1273c	CLIP-seq
MIRT2455250	hsa-miR-1283	CLIP-seq
MIRT1187149	hsa-miR-1293	CLIP-seq
MIRT1187150	hsa-miR-186	CLIP-seq
MIRT1187152	hsa-miR-3120-5p	CLIP-seq
MIRT1187153	hsa-miR-3122	CLIP-seq
MIRT1187154	hsa-miR-3133	CLIP-seq
MIRT1187155	hsa-miR-3165	CLIP-seq
MIRT1187158	hsa-miR-323-5p	CLIP-seq
MIRT1187159	hsa-miR-335	CLIP-seq
MIRT1187161	hsa-miR-3613-3p	CLIP-seq
MIRT1187162	hsa-miR-3614-5p	CLIP-seq
MIRT1187163	hsa-miR-3689a-3p	CLIP-seq
MIRT1187164	hsa-miR-3689c	CLIP-seq
MIRT1187165	hsa-miR-371-5p	CLIP-seq
MIRT1187166	hsa-miR-371b-5p	CLIP-seq
MIRT1187167	hsa-miR-3913-5p	CLIP-seq
MIRT1187168	hsa-miR-4252	CLIP-seq
MIRT1187171	hsa-miR-4424	CLIP-seq
MIRT1187172	hsa-miR-4433	CLIP-seq
MIRT1187173	hsa-miR-4455	CLIP-seq
MIRT1187174	hsa-miR-4459	CLIP-seq
MIRT1187175	hsa-miR-4466	CLIP-seq
MIRT1187176	hsa-miR-4483	CLIP-seq
MIRT1187177	hsa-miR-4486	CLIP-seq
MIRT1187181	hsa-miR-4649-5p	CLIP-seq
MIRT1187182	hsa-miR-4653-3p	CLIP-seq
MIRT2283380	hsa-miR-4712-5p	CLIP-seq
MIRT1187183	hsa-miR-4728-5p	CLIP-seq
MIRT1187184	hsa-miR-4768-3p	CLIP-seq
MIRT1187185	hsa-miR-4778-5p	CLIP-seq
MIRT1187186	hsa-miR-4793-3p	CLIP-seq
MIRT2455257	hsa-miR-495	CLIP-seq
MIRT1187187	hsa-miR-508-5p	CLIP-seq
MIRT1187190	hsa-miR-548a-3p	CLIP-seq
MIRT1187191	hsa-miR-548e	CLIP-seq
MIRT1187192	hsa-miR-548f	CLIP-seq
MIRT2054214	hsa-miR-550a	CLIP-seq
MIRT1187195	hsa-miR-609	CLIP-seq
MIRT1187197	hsa-miR-661	CLIP-seq
MIRT1187198	hsa-miR-675	CLIP-seq
MIRT1187200	hsa-miR-766	CLIP-seq
MIRT2283392	hsa-miR-770-5p	CLIP-seq
MIRT1187201	hsa-miR-876-3p	CLIP-seq

Show/Hide all (37)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002683	Process	Negative regulation of immune system process	IEA
GO:0005515	Function	Protein binding	IPI	24560620, 25277106
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IDA	15705585, 24560620, 25277106
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0007249	Process	Canonical NF-kappaB signal transduction	IDA	15705585
GO:0007249	Process	Canonical NF-kappaB signal transduction	IEA
GO:0032088	Process	Negative regulation of NF-kappaB transcription factor activity	IDA	15705585
GO:0032687	Process	Negative regulation of interferon-alpha production	ISS
GO:0032688	Process	Negative regulation of interferon-beta production	ISS
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	22863753
GO:0032715	Process	Negative regulation of interleukin-6 production	IEA
GO:0032715	Process	Negative regulation of interleukin-6 production	IMP	22863753
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IDA	22863753
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IEA
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IMP	22863753
GO:0034451	Component	Centriolar satellite	IDA
GO:0036312	Function	Phosphatidylinositol 3-kinase regulatory subunit binding	ISS
GO:0042110	Process	T cell activation	IEP	15705585
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IBA
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IEA
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IMP	22863753
GO:0045088	Process	Regulation of innate immune response	IEA
GO:0045824	Process	Negative regulation of innate immune response	ISS
GO:0048147	Process	Negative regulation of fibroblast proliferation	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	24560620
GO:0050680	Process	Negative regulation of epithelial cell proliferation	ISS
GO:0050728	Process	Negative regulation of inflammatory response	IDA	25277106
GO:0050728	Process	Negative regulation of inflammatory response	IEA
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ISS
GO:0080090	Process	Regulation of primary metabolic process	IEA
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	ISS
GO:1900226	Process	Negative regulation of NLRP3 inflammasome complex assembly	IDA	25277106
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	IDA	25277106

MIM	HGNC	e!Ensembl
615648	29889	ENSG00000167984

Q7RTR2

Protein name

NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3)

Protein function

Negative regulator of the innate immune response (PubMed:15705585, PubMed:22863753, PubMed:25277106). Attenuates signaling pathways activated by Toll-like receptors (TLRs) and the DNA sensor STING/TMEM173 in response to pathogen-associated molec

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05729	NACHT	139 → 305	NACHT domain	Domain
PF17779	NOD2_WH	395 → 453	NOD2 winged helix domain	Domain
PF17776	NLRC4_HD2	455 → 582	NLRC4 helical domain HD2	Domain
PF13516	LRR_6	664 → 687	Leucine Rich repeat	Repeat
PF13516	LRR_6	692 → 715	Leucine Rich repeat	Repeat
PF13516	LRR_6	721 → 743	Leucine Rich repeat	Repeat
PF13516	LRR_6	776 → 799	Leucine Rich repeat	Repeat
PF13516	LRR_6	804 → 827	Leucine Rich repeat	Repeat
PF13516	LRR_6	832 → 855	Leucine Rich repeat	Repeat
PF13516	LRR_6	860 → 883	Leucine Rich repeat	Repeat
PF13516	LRR_6	888 → 911	Leucine Rich repeat	Repeat
PF13516	LRR_6	916 → 939	Leucine Rich repeat	Repeat
PF13516	LRR_6	972 → 995	Leucine Rich repeat	Repeat
PF13516	LRR_6	1000 → 1023	Leucine Rich repeat	Repeat
PF13516	LRR_6	1028 → 1051	Leucine Rich repeat	Repeat

Sequence

MRKQEVRTGREAGQGHGTGSPAEQVKALMDLLAGKGSQGSQAPQALDRTPDAPLGPCSND
SRIQRHRKALLSKVGGGPELGGPWHRLASLLLVEGLTDLQLREHDFTQVEATRGGGHPAR
TVALDRLFLPLSRVSVPPRVSITIGVAGMGKTTLVRHFVRLWAHGQVGKDFSLVLPLTFR
DLNTHEKLCADRLICSVFPHVGEPSLAVAVPARALLILDGLDECRTPLDFSNTVACTDPK
KEIPVDHLITNIIRGNLFPEVSIWITSRPSASGQIPGGLVDRMTEIRGFNEEEIKVCLEQ
MFPEDQALLGWMLSQVQADRALYLMCTVPAFCRLTGMALGHLWRSRTGPQDAELWPPRTL
CELYSWYFRMALSGEGQEKGKASPRIEQVAHGGRKMVGTLGRLAFHGLLKKKYVFYEQDM
KAFGVDLALLQGAPCSCFLQREETLASSVAYCFTHLSLQEFVAAAYYYGASRRAIFDLFT
ESGVSWPRLGFLTHFRSAAQRAMQAEDGRLDVFLRFLSGLLSPRVNALLAGSLLAQGEHQ
AYRTQVAELLQGCLRPDAAVCARAINVLHCLHELQHTELARSVEEAMESGALARLTGPAH
RAALAYLLQVSDACAQEANLSLSLSQGVLQSLLPQLLYCRKLRLDTNQFQDPVMELLGSV
LSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKI
NRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSL
KELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLS
LRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWN
FIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGA
SGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAI
CIATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNAPTCTVEM

Sequence length

1065

Interactions

View interactions

	Reactome
			IRF3-mediated induction of type I IFN

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Cervical cancer	Likely benign	rs146476058	RCV005929402
Gastric cancer	Likely benign	rs146476058	RCV005929403
Malignant tumor of urinary bladder	Likely benign	rs146476058	RCV005929401
Thyroid cancer, nonmedullary, 1	Likely benign	rs146476058	RCV005929404

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Inhibit	36808166
Alzheimer Disease	Associate	35173266
Carcinogenesis	Associate	36808166
Carcinoma Hepatocellular	Associate	32148377
Cartilage Diseases	Associate	37312878
Colorectal Neoplasms	Inhibit	26378020
Common Variable Immunodeficiency	Associate	32047491
Dementia	Associate	35173266
Granulomatosis with Polyangiitis	Associate	21412229
Inflammation	Associate	26378020, 35173266, 36808166, 37312878
Lupus Erythematosus Systemic	Associate	37312878
Neoplasms	Inhibit	26378020, 36808166
Neoplasms	Associate	32034058, 32047491
Nerve Degeneration	Associate	35173266
Stomach Neoplasms	Associate	32034058

NLRC3 (NLR family CARD domain containing 3)