Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	1948
Gene name	Ephrin B2
Gene symbol	EFNB2
Synonyms (NCBI Gene)	EPLG5HTKLHtk-LLERK5ephrin-B2
Chromosome	13
Chromosome location	13q33.3
Summary	This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006337	hsa-miR-20b-5p	Luciferase reporter assay	22438230
MIRT006337	hsa-miR-20b-5p	Luciferase reporter assay	22438230
MIRT006337	hsa-miR-20b-5p	Luciferase reporter assay	22438230
MIRT007101	hsa-miR-204-5p	Luciferase reporter assayqRT-PCRWestern blot	23204229
MIRT007101	hsa-miR-204-5p	Luciferase reporter assayqRT-PCRWestern blot	23204229
MIRT020031	hsa-miR-375	Microarray	20215506
MIRT024211	hsa-miR-218-5p	Sequencing	20371350
MIRT024662	hsa-miR-215-5p	Microarray	19074876
MIRT026948	hsa-miR-192-5p	Microarray	19074876
MIRT027181	hsa-miR-103a-3p	Sequencing	20371350
MIRT027920	hsa-miR-96-5p	Sequencing	20371350
MIRT032048	hsa-miR-16-5p	Proteomics	18668040
MIRT043356	hsa-miR-331-3p	CLASH	23622248
MIRT438381	hsa-miR-582-5p	Luciferase reporter assayWestern blotqRT-PCR	25176332
MIRT438381	hsa-miR-582-5p	Luciferase reporter assayWestern blotqRT-PCR	25176332
MIRT438381	hsa-miR-582-5p	Luciferase reporter assayWestern blotqRT-PCR	25176332
MIRT438381	hsa-miR-582-5p	Luciferase reporter assayWestern blotqRT-PCR	25176332
MIRT537820	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT537819	hsa-miR-503-5p	PAR-CLIP	20371350
MIRT537818	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT537817	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT537816	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT032048	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT537815	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT537814	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT537813	hsa-miR-3662	PAR-CLIP	20371350
MIRT572103	hsa-miR-8066	PAR-CLIP	20371350
MIRT537812	hsa-miR-646	PAR-CLIP	20371350
MIRT537811	hsa-miR-3163	PAR-CLIP	20371350
MIRT537809	hsa-miR-924	PAR-CLIP	20371350
MIRT537808	hsa-miR-8077	PAR-CLIP	20371350
MIRT537807	hsa-miR-3689a-5p	PAR-CLIP	20371350
MIRT537806	hsa-miR-3689b-5p	PAR-CLIP	20371350
MIRT537805	hsa-miR-3689e	PAR-CLIP	20371350
MIRT537804	hsa-miR-3689f	PAR-CLIP	20371350
MIRT537803	hsa-miR-4524a-5p	PAR-CLIP	20371350
MIRT537802	hsa-miR-4524b-5p	PAR-CLIP	20371350
MIRT537800	hsa-miR-627-5p	PAR-CLIP	20371350
MIRT537798	hsa-miR-3161	PAR-CLIP	20371350
MIRT537820	hsa-miR-6838-5p	PAR-CLIP	22012620
MIRT537819	hsa-miR-503-5p	PAR-CLIP	22012620
MIRT537818	hsa-miR-497-5p	PAR-CLIP	22012620
MIRT537817	hsa-miR-424-5p	PAR-CLIP	22012620
MIRT537816	hsa-miR-195-5p	PAR-CLIP	22012620
MIRT032048	hsa-miR-16-5p	PAR-CLIP	22012620
MIRT537815	hsa-miR-15a-5p	PAR-CLIP	22012620
MIRT537814	hsa-miR-15b-5p	PAR-CLIP	22012620
MIRT537813	hsa-miR-3662	PAR-CLIP	22012620
MIRT537812	hsa-miR-646	PAR-CLIP	22012620
MIRT537811	hsa-miR-3163	PAR-CLIP	22012620
MIRT537810	hsa-miR-339-5p	PAR-CLIP	22012620
MIRT537809	hsa-miR-924	PAR-CLIP	22012620
MIRT537808	hsa-miR-8077	PAR-CLIP	22012620
MIRT537807	hsa-miR-3689a-5p	PAR-CLIP	22012620
MIRT537806	hsa-miR-3689b-5p	PAR-CLIP	22012620
MIRT537805	hsa-miR-3689e	PAR-CLIP	22012620
MIRT537804	hsa-miR-3689f	PAR-CLIP	22012620
MIRT537803	hsa-miR-4524a-5p	PAR-CLIP	22012620
MIRT537802	hsa-miR-4524b-5p	PAR-CLIP	22012620
MIRT537801	hsa-miR-670-5p	PAR-CLIP	22012620
MIRT537800	hsa-miR-627-5p	PAR-CLIP	22012620
MIRT537798	hsa-miR-3161	PAR-CLIP	22012620
MIRT537799	hsa-miR-4755-5p	PAR-CLIP	22012620
MIRT537797	hsa-miR-5006-3p	PAR-CLIP	22012620
MIRT537796	hsa-miR-4446-5p	PAR-CLIP	22012620
MIRT537820	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT537819	hsa-miR-503-5p	PAR-CLIP	20371350
MIRT537818	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT537817	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT537816	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT032048	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT537815	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT537814	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT537813	hsa-miR-3662	PAR-CLIP	20371350
MIRT572103	hsa-miR-8066	PAR-CLIP	20371350
MIRT537812	hsa-miR-646	PAR-CLIP	20371350
MIRT537811	hsa-miR-3163	PAR-CLIP	20371350
MIRT537809	hsa-miR-924	PAR-CLIP	20371350
MIRT537808	hsa-miR-8077	PAR-CLIP	20371350
MIRT537807	hsa-miR-3689a-5p	PAR-CLIP	20371350
MIRT537806	hsa-miR-3689b-5p	PAR-CLIP	20371350
MIRT537805	hsa-miR-3689e	PAR-CLIP	20371350
MIRT537804	hsa-miR-3689f	PAR-CLIP	20371350
MIRT537803	hsa-miR-4524a-5p	PAR-CLIP	20371350
MIRT537802	hsa-miR-4524b-5p	PAR-CLIP	20371350
MIRT537800	hsa-miR-627-5p	PAR-CLIP	20371350
MIRT537798	hsa-miR-3161	PAR-CLIP	20371350
MIRT537820	hsa-miR-6838-5p	PAR-CLIP	22012620
MIRT537819	hsa-miR-503-5p	PAR-CLIP	22012620
MIRT537818	hsa-miR-497-5p	PAR-CLIP	22012620
MIRT537817	hsa-miR-424-5p	PAR-CLIP	22012620
MIRT537816	hsa-miR-195-5p	PAR-CLIP	22012620
MIRT032048	hsa-miR-16-5p	PAR-CLIP	22012620
MIRT537815	hsa-miR-15a-5p	PAR-CLIP	22012620
MIRT537814	hsa-miR-15b-5p	PAR-CLIP	22012620
MIRT537813	hsa-miR-3662	PAR-CLIP	22012620
MIRT537812	hsa-miR-646	PAR-CLIP	22012620
MIRT537811	hsa-miR-3163	PAR-CLIP	22012620
MIRT537810	hsa-miR-339-5p	PAR-CLIP	22012620
MIRT537809	hsa-miR-924	PAR-CLIP	22012620
MIRT537808	hsa-miR-8077	PAR-CLIP	22012620
MIRT537807	hsa-miR-3689a-5p	PAR-CLIP	22012620
MIRT537806	hsa-miR-3689b-5p	PAR-CLIP	22012620
MIRT537805	hsa-miR-3689e	PAR-CLIP	22012620
MIRT537804	hsa-miR-3689f	PAR-CLIP	22012620
MIRT537803	hsa-miR-4524a-5p	PAR-CLIP	22012620
MIRT537802	hsa-miR-4524b-5p	PAR-CLIP	22012620
MIRT537801	hsa-miR-670-5p	PAR-CLIP	22012620
MIRT537800	hsa-miR-627-5p	PAR-CLIP	22012620
MIRT537798	hsa-miR-3161	PAR-CLIP	22012620
MIRT537799	hsa-miR-4755-5p	PAR-CLIP	22012620
MIRT537797	hsa-miR-5006-3p	PAR-CLIP	22012620
MIRT537796	hsa-miR-4446-5p	PAR-CLIP	22012620
MIRT954232	hsa-miR-1	CLIP-seq
MIRT954233	hsa-miR-101	CLIP-seq
MIRT954234	hsa-miR-128	CLIP-seq
MIRT954235	hsa-miR-134	CLIP-seq
MIRT954236	hsa-miR-144	CLIP-seq
MIRT954237	hsa-miR-1470	CLIP-seq
MIRT954238	hsa-miR-206	CLIP-seq
MIRT954239	hsa-miR-27a	CLIP-seq
MIRT954240	hsa-miR-27b	CLIP-seq
MIRT954241	hsa-miR-3074-5p	CLIP-seq
MIRT954242	hsa-miR-3118	CLIP-seq
MIRT954243	hsa-miR-3119	CLIP-seq
MIRT954244	hsa-miR-3164	CLIP-seq
MIRT954245	hsa-miR-3190	CLIP-seq
MIRT954246	hsa-miR-3673	CLIP-seq
MIRT954247	hsa-miR-3920	CLIP-seq
MIRT954248	hsa-miR-4326	CLIP-seq
MIRT954249	hsa-miR-4491	CLIP-seq
MIRT954250	hsa-miR-4501	CLIP-seq
MIRT954251	hsa-miR-4657	CLIP-seq
MIRT954252	hsa-miR-4659a-3p	CLIP-seq
MIRT954253	hsa-miR-4659b-3p	CLIP-seq
MIRT954254	hsa-miR-4667-3p	CLIP-seq
MIRT954255	hsa-miR-494	CLIP-seq
MIRT954256	hsa-miR-5096	CLIP-seq
MIRT954257	hsa-miR-513a-5p	CLIP-seq
MIRT954258	hsa-miR-562	CLIP-seq
MIRT954259	hsa-miR-576-3p	CLIP-seq
MIRT954260	hsa-miR-613	CLIP-seq
MIRT954261	hsa-miR-617	CLIP-seq
MIRT954262	hsa-miR-642a	CLIP-seq
MIRT1982570	hsa-miR-153	CLIP-seq
MIRT1982571	hsa-miR-3120-3p	CLIP-seq
MIRT1982572	hsa-miR-3127-3p	CLIP-seq
MIRT1982573	hsa-miR-3652	CLIP-seq
MIRT1982574	hsa-miR-3679-3p	CLIP-seq
MIRT1982575	hsa-miR-3942-3p	CLIP-seq
MIRT1982576	hsa-miR-409-5p	CLIP-seq
MIRT1982577	hsa-miR-412	CLIP-seq
MIRT1982578	hsa-miR-4318	CLIP-seq
MIRT1982579	hsa-miR-4430	CLIP-seq
MIRT1982580	hsa-miR-4474-3p	CLIP-seq
MIRT1982581	hsa-miR-448	CLIP-seq
MIRT1982582	hsa-miR-4505	CLIP-seq
MIRT1982583	hsa-miR-450b-5p	CLIP-seq
MIRT1982584	hsa-miR-4693-5p	CLIP-seq
MIRT1982585	hsa-miR-4699-3p	CLIP-seq
MIRT1982586	hsa-miR-4796-5p	CLIP-seq
MIRT1982587	hsa-miR-507	CLIP-seq
MIRT1982588	hsa-miR-518a-5p	CLIP-seq
MIRT1982589	hsa-miR-527	CLIP-seq
MIRT1982590	hsa-miR-557	CLIP-seq
MIRT1982591	hsa-miR-892a	CLIP-seq
MIRT954233	hsa-miR-101	CLIP-seq
MIRT2217437	hsa-miR-1202	CLIP-seq
MIRT2217438	hsa-miR-122	CLIP-seq
MIRT2217439	hsa-miR-1250	CLIP-seq
MIRT2217440	hsa-miR-1273f	CLIP-seq
MIRT2217441	hsa-miR-1321	CLIP-seq
MIRT2217442	hsa-miR-143	CLIP-seq
MIRT954236	hsa-miR-144	CLIP-seq
MIRT2217443	hsa-miR-15a	CLIP-seq
MIRT2217444	hsa-miR-15b	CLIP-seq
MIRT2217445	hsa-miR-16	CLIP-seq
MIRT2217446	hsa-miR-193a-3p	CLIP-seq
MIRT2217447	hsa-miR-193b	CLIP-seq
MIRT2217448	hsa-miR-195	CLIP-seq
MIRT2217449	hsa-miR-197	CLIP-seq
MIRT2217450	hsa-miR-19a	CLIP-seq
MIRT2217451	hsa-miR-19b	CLIP-seq
MIRT2217452	hsa-miR-200b	CLIP-seq
MIRT2217453	hsa-miR-200c	CLIP-seq
MIRT2217454	hsa-miR-218	CLIP-seq
MIRT2217455	hsa-miR-3065-3p	CLIP-seq
MIRT2217456	hsa-miR-3117-5p	CLIP-seq
MIRT1982571	hsa-miR-3120-3p	CLIP-seq
MIRT2217457	hsa-miR-3130-3p	CLIP-seq
MIRT2217458	hsa-miR-3135b	CLIP-seq
MIRT2217459	hsa-miR-3137	CLIP-seq
MIRT2217460	hsa-miR-3152-3p	CLIP-seq
MIRT2217461	hsa-miR-3194-5p	CLIP-seq
MIRT2217462	hsa-miR-346	CLIP-seq
MIRT1982573	hsa-miR-3652	CLIP-seq
MIRT2217463	hsa-miR-3657	CLIP-seq
MIRT2217464	hsa-miR-3682-5p	CLIP-seq
MIRT2217465	hsa-miR-3687	CLIP-seq
MIRT2217466	hsa-miR-369-3p	CLIP-seq
MIRT2217467	hsa-miR-384	CLIP-seq
MIRT2217468	hsa-miR-3922-5p	CLIP-seq
MIRT2217469	hsa-miR-3972	CLIP-seq
MIRT1982577	hsa-miR-412	CLIP-seq
MIRT2217470	hsa-miR-424	CLIP-seq
MIRT2217471	hsa-miR-4269	CLIP-seq
MIRT2217472	hsa-miR-429	CLIP-seq
MIRT2217473	hsa-miR-4297	CLIP-seq
MIRT1982578	hsa-miR-4318	CLIP-seq
MIRT2217474	hsa-miR-4420	CLIP-seq
MIRT2217475	hsa-miR-4423-5p	CLIP-seq
MIRT1982579	hsa-miR-4430	CLIP-seq
MIRT2217476	hsa-miR-4442	CLIP-seq
MIRT2217477	hsa-miR-4477b	CLIP-seq
MIRT954249	hsa-miR-4491	CLIP-seq
MIRT2217478	hsa-miR-4514	CLIP-seq
MIRT2217479	hsa-miR-4520a-3p	CLIP-seq
MIRT2217480	hsa-miR-4520b-3p	CLIP-seq
MIRT2217481	hsa-miR-4527	CLIP-seq
MIRT2217482	hsa-miR-455-5p	CLIP-seq
MIRT954251	hsa-miR-4657	CLIP-seq
MIRT2217483	hsa-miR-4692	CLIP-seq
MIRT1982584	hsa-miR-4693-5p	CLIP-seq
MIRT2217484	hsa-miR-4695-3p	CLIP-seq
MIRT1982585	hsa-miR-4699-3p	CLIP-seq
MIRT2217485	hsa-miR-4708-5p	CLIP-seq
MIRT2217486	hsa-miR-4728-5p	CLIP-seq
MIRT2217487	hsa-miR-4739	CLIP-seq
MIRT2217488	hsa-miR-4742-5p	CLIP-seq
MIRT2217489	hsa-miR-4756-5p	CLIP-seq
MIRT2217490	hsa-miR-4765	CLIP-seq
MIRT2217491	hsa-miR-4770	CLIP-seq
MIRT2217492	hsa-miR-4779	CLIP-seq
MIRT2217493	hsa-miR-4783-3p	CLIP-seq
MIRT2217494	hsa-miR-4793-3p	CLIP-seq
MIRT954255	hsa-miR-494	CLIP-seq
MIRT2217495	hsa-miR-497	CLIP-seq
MIRT2217496	hsa-miR-510	CLIP-seq
MIRT2217497	hsa-miR-515-3p	CLIP-seq
MIRT1982588	hsa-miR-518a-5p	CLIP-seq
MIRT2217498	hsa-miR-519e	CLIP-seq
MIRT2217499	hsa-miR-520d-5p	CLIP-seq
MIRT2217500	hsa-miR-520g	CLIP-seq
MIRT2217501	hsa-miR-520h	CLIP-seq
MIRT2217502	hsa-miR-524-5p	CLIP-seq
MIRT1982589	hsa-miR-527	CLIP-seq
MIRT2217503	hsa-miR-532-5p	CLIP-seq
MIRT2217504	hsa-miR-544	CLIP-seq
MIRT2217505	hsa-miR-545	CLIP-seq
MIRT2217506	hsa-miR-548p	CLIP-seq
MIRT954259	hsa-miR-576-3p	CLIP-seq
MIRT2217507	hsa-miR-578	CLIP-seq
MIRT2217508	hsa-miR-636	CLIP-seq
MIRT954262	hsa-miR-642a	CLIP-seq
MIRT2217509	hsa-miR-765	CLIP-seq
MIRT1982591	hsa-miR-892a	CLIP-seq
MIRT954233	hsa-miR-101	CLIP-seq
MIRT2521469	hsa-miR-1184	CLIP-seq
MIRT2217437	hsa-miR-1202	CLIP-seq
MIRT2521470	hsa-miR-1228	CLIP-seq
MIRT2521471	hsa-miR-127-5p	CLIP-seq
MIRT954236	hsa-miR-144	CLIP-seq
MIRT2521472	hsa-miR-151-3p	CLIP-seq
MIRT2217450	hsa-miR-19a	CLIP-seq
MIRT2217451	hsa-miR-19b	CLIP-seq
MIRT2521473	hsa-miR-300	CLIP-seq
MIRT2217455	hsa-miR-3065-3p	CLIP-seq
MIRT2217456	hsa-miR-3117-5p	CLIP-seq
MIRT2521474	hsa-miR-3121-3p	CLIP-seq
MIRT2521475	hsa-miR-3125	CLIP-seq
MIRT2217458	hsa-miR-3135b	CLIP-seq
MIRT2217459	hsa-miR-3137	CLIP-seq
MIRT2521476	hsa-miR-3173-3p	CLIP-seq
MIRT2521477	hsa-miR-3180-5p	CLIP-seq
MIRT2217461	hsa-miR-3194-5p	CLIP-seq
MIRT2521478	hsa-miR-329	CLIP-seq
MIRT2521479	hsa-miR-3619-3p	CLIP-seq
MIRT2521480	hsa-miR-362-3p	CLIP-seq
MIRT1982573	hsa-miR-3652	CLIP-seq
MIRT2521481	hsa-miR-3663-3p	CLIP-seq
MIRT2217465	hsa-miR-3687	CLIP-seq
MIRT2521482	hsa-miR-377	CLIP-seq
MIRT2521483	hsa-miR-381	CLIP-seq
MIRT2521484	hsa-miR-3910	CLIP-seq
MIRT2521485	hsa-miR-3916	CLIP-seq
MIRT2521486	hsa-miR-3940-3p	CLIP-seq
MIRT2521487	hsa-miR-3941	CLIP-seq
MIRT1982575	hsa-miR-3942-3p	CLIP-seq
MIRT2217469	hsa-miR-3972	CLIP-seq
MIRT2521488	hsa-miR-4271	CLIP-seq
MIRT2217475	hsa-miR-4423-5p	CLIP-seq
MIRT1982579	hsa-miR-4430	CLIP-seq
MIRT2217476	hsa-miR-4442	CLIP-seq
MIRT2521489	hsa-miR-4504	CLIP-seq
MIRT2217480	hsa-miR-4520b-3p	CLIP-seq
MIRT2521490	hsa-miR-4529-3p	CLIP-seq
MIRT2521491	hsa-miR-4533	CLIP-seq
MIRT2521492	hsa-miR-4535	CLIP-seq
MIRT2521493	hsa-miR-4645-3p	CLIP-seq
MIRT2521494	hsa-miR-4652-3p	CLIP-seq
MIRT2521495	hsa-miR-4652-5p	CLIP-seq
MIRT2521496	hsa-miR-4666-3p	CLIP-seq
MIRT2521497	hsa-miR-4677-3p	CLIP-seq
MIRT2521498	hsa-miR-4679	CLIP-seq
MIRT2521499	hsa-miR-4708-3p	CLIP-seq
MIRT2521500	hsa-miR-4725-3p	CLIP-seq
MIRT2521501	hsa-miR-4725-5p	CLIP-seq
MIRT2217486	hsa-miR-4728-5p	CLIP-seq
MIRT2521502	hsa-miR-4747-5p	CLIP-seq
MIRT2521503	hsa-miR-4759	CLIP-seq
MIRT2521504	hsa-miR-4776-5p	CLIP-seq
MIRT2217492	hsa-miR-4779	CLIP-seq
MIRT2521505	hsa-miR-4789-3p	CLIP-seq
MIRT2521506	hsa-miR-4789-5p	CLIP-seq
MIRT2521507	hsa-miR-485-3p	CLIP-seq
MIRT2521508	hsa-miR-487a	CLIP-seq
MIRT954255	hsa-miR-494	CLIP-seq
MIRT2521509	hsa-miR-504	CLIP-seq
MIRT1982587	hsa-miR-507	CLIP-seq
MIRT2521510	hsa-miR-508-5p	CLIP-seq
MIRT1982588	hsa-miR-518a-5p	CLIP-seq
MIRT2521511	hsa-miR-518d-5p	CLIP-seq
MIRT2521512	hsa-miR-519b-5p	CLIP-seq
MIRT2521513	hsa-miR-519c-5p	CLIP-seq
MIRT2521514	hsa-miR-520c-5p	CLIP-seq
MIRT2217500	hsa-miR-520g	CLIP-seq
MIRT2217501	hsa-miR-520h	CLIP-seq
MIRT2521515	hsa-miR-521	CLIP-seq
MIRT2521516	hsa-miR-526a	CLIP-seq
MIRT1982589	hsa-miR-527	CLIP-seq
MIRT2521517	hsa-miR-542-3p	CLIP-seq
MIRT1982590	hsa-miR-557	CLIP-seq
MIRT2521518	hsa-miR-603	CLIP-seq
MIRT2521519	hsa-miR-618	CLIP-seq
MIRT2521520	hsa-miR-642b	CLIP-seq
MIRT2217509	hsa-miR-765	CLIP-seq
MIRT2521521	hsa-miR-873	CLIP-seq
MIRT2521522	hsa-miR-877	CLIP-seq
MIRT2217450	hsa-miR-19a	CLIP-seq
MIRT2217451	hsa-miR-19b	CLIP-seq
MIRT2521493	hsa-miR-4645-3p	CLIP-seq
MIRT2521503	hsa-miR-4759	CLIP-seq
MIRT954255	hsa-miR-494	CLIP-seq
MIRT2521511	hsa-miR-518d-5p	CLIP-seq
MIRT2521512	hsa-miR-519b-5p	CLIP-seq
MIRT2521513	hsa-miR-519c-5p	CLIP-seq
MIRT2521514	hsa-miR-520c-5p	CLIP-seq
MIRT2521516	hsa-miR-526a	CLIP-seq
MIRT2521519	hsa-miR-618	CLIP-seq

Show/Hide all (59)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IDA	12734395
GO:0001525	Process	Angiogenesis	IDA	12734395, 22555806
GO:0001525	Process	Angiogenesis	IEA
GO:0001525	Process	Angiogenesis	IMP	28687708, 30578106
GO:0001618	Function	Virus receptor activity	IEA
GO:0001945	Process	Lymph vessel development	IEA
GO:0002042	Process	Cell migration involved in sprouting angiogenesis	IDA	12734395
GO:0005102	Function	Signaling receptor binding	IEA
GO:0005515	Function	Protein binding	IPI	12606549, 15764601, 18488039, 19836338, 26481148, 28514442, 28904190, 32296183, 33961781, 35384245
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	28931592
GO:0005886	Component	Plasma membrane	IDA	17251577
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005912	Component	Adherens junction	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007155	Process	Cell adhesion	IDA	12734395
GO:0007399	Process	Nervous system development	IEA
GO:0007411	Process	Axon guidance	IBA
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	26268439
GO:0009653	Process	Anatomical structure morphogenesis	TAS	9630219
GO:0009887	Process	Animal organ morphogenesis	IEA
GO:0010839	Process	Negative regulation of keratinocyte proliferation	IEA
GO:0010977	Process	Negative regulation of neuron projection development	IDA	10066262
GO:0016020	Component	Membrane	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0030297	Function	Transmembrane receptor protein tyrosine kinase activator activity	IDA	12734395, 16867992, 22555806
GO:0030425	Component	Dendrite	IEA
GO:0031295	Process	T cell costimulation	IEA
GO:0034332	Process	Adherens junction organization	IEA
GO:0042734	Component	Presynaptic membrane	IBA
GO:0042734	Component	Presynaptic membrane	IEA
GO:0043616	Process	Keratinocyte proliferation	IEA
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0046875	Function	Ephrin receptor binding	IBA
GO:0046875	Function	Ephrin receptor binding	IEA
GO:0048013	Process	Ephrin receptor signaling pathway	IBA
GO:0048013	Process	Ephrin receptor signaling pathway	IDA	12734395
GO:0048013	Process	Ephrin receptor signaling pathway	IEA
GO:0048013	Process	Ephrin receptor signaling pathway	IMP	22555806
GO:0048018	Function	Receptor ligand activity	IDA	12734395, 16867992, 22555806
GO:0048514	Process	Blood vessel morphogenesis	IBA
GO:0048514	Process	Blood vessel morphogenesis	IEA
GO:0048514	Process	Blood vessel morphogenesis	IEA
GO:0048845	Process	Venous blood vessel morphogenesis	IEA
GO:0050920	Process	Regulation of chemotaxis	IDA	12734395
GO:0070161	Component	Anchoring junction	IEA
GO:0071222	Process	Cellular response to lipopolysaccharide	IEA
GO:0072178	Process	Nephric duct morphogenesis	IEA
GO:0098685	Component	Schaffer collateral - CA1 synapse	IEA
GO:0098839	Component	Postsynaptic density membrane	IEA
GO:0098978	Component	Glutamatergic synapse	IBA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099054	Process	Presynapse assembly	IEA
GO:0099072	Process	Regulation of postsynaptic membrane neurotransmitter receptor levels	IEA
GO:0099149	Process	Regulation of postsynaptic neurotransmitter receptor internalization	IEA
GO:1903849	Process	Positive regulation of aorta morphogenesis	IEA
GO:2000727	Process	Positive regulation of cardiac muscle cell differentiation	IEA
GO:2000727	Process	Positive regulation of cardiac muscle cell differentiation	ISS	17336907

MIM	HGNC	e!Ensembl
600527	3227	ENSG00000125266

P52799

Protein name

Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L)

Protein function

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing o

PDB

2HLE , 2I85 , 2VSK , 2VSM , 2WO2 , 3GXU , 4UF7 , 6P7Y , 6PDL

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00812	Ephrin	29 → 164	Ephrin	Domain

Tissue specificity

TISSUE SPECIFICITY: Lung and kidney.

Sequence

MAVRRDSVWKYCWGVLMVLCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDI
ICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPN
LWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPT
RRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFAGIASGCIIFIV
IIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNNGSEPSDIIIPLRTADSVF
CPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV

Sequence length

333

Interactions

View interactions

	KEGG		Reactome
	Axon guidance		EPH-Ephrin signaling EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
EFNB2-related disorder	Likely benign	rs144052492, rs958782701, rs141519659, rs553183986	RCV003964641 RCV003981685 RCV003967287 RCV003954343

Show/Hide Text Mining Associations (49)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
13q deletion syndrome	Associate	28393221
Adenocarcinoma	Associate	32362422
Adenocarcinoma of Lung	Associate	30106131, 33021972, 39273449
Asthma	Associate	28599074
Atherosclerosis	Associate	21672356
Bone Diseases	Associate	19664212
Breast Neoplasms	Associate	23981902, 31638179
Calcinosis Cutis	Associate	32362422
Capillary Malformation Arteriovenous Malformation	Associate	32286515
Carcinogenesis	Associate	24771266
Carcinoma Hepatocellular	Associate	25645722
Carcinoma Pancreatic Ductal	Associate	26345967, 32036221
Carcinoma Renal Cell	Associate	33761933
Cardiovascular Diseases	Associate	28393221, 30423812
Cholangiocarcinoma	Associate	25012246
Colonic Neoplasms	Associate	11920461
Colorectal Neoplasms	Associate	32036221, 32751332
Crohn Disease	Associate	15996027
Endometrial Neoplasms	Associate	17108150
Epilepsy	Associate	40045230
Esophageal Squamous Cell Carcinoma	Inhibit	24771266
Glioblastoma	Associate	19728339
Glioma	Associate	19728339
Heart Defects Congenital	Associate	28393221
Heart Septal Defects Ventricular	Associate	30423812
HIV Infections	Inhibit	23314923
Inflammatory Bowel Diseases	Stimulate	15996027
Intracranial Arteriovenous Malformations	Associate	24517927, 32286515
Kidney Failure Chronic	Associate	18580054
Medulloblastoma	Associate	25258252
Neoplasm Metastasis	Associate	25012246, 31638179
Neoplasms	Associate	17108150, 17380111, 18231102, 24517927, 25645722, 26044849, 33648511, 36402751
Neoplasms	Stimulate	20233847, 32036221, 39273449
Neuroblastoma	Associate	21109931
Osteoarthritis	Associate	39213112
Osteoporosis	Associate	39213112
Osteosarcoma	Associate	12209731
Ovarian Neoplasms	Associate	18231102
Pancreatic Neoplasms	Associate	26345967, 33648511
Prostatic Neoplasms	Associate	28035996
Sarcoma Kaposi	Associate	15471957
Squamous Cell Carcinoma of Head and Neck	Associate	32036221, 36438491
Stomach Neoplasms	Associate	12136247
Thyroid Cancer Papillary	Associate	27986811
Urinary Bladder Neoplasms	Associate	28320388
Urogenital Abnormalities	Associate	28393221
Varicose Veins	Associate	26808710
Venous Thromboembolism	Associate	28910333
Vitreoretinopathy Proliferative	Associate	19696168

EFNB2 (ephrin B2)