EFNA5 (ephrin A5)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1946 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Ephrin A5 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EFNA5 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS |
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Chromosome
Chromosome number
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5 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P52803 | ||||||||||
| Protein name | Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) | ||||||||||
| Protein function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on ad | ||||||||||
| PDB | 2X11 , 3MX0 , 4BK5 , 4BKA , 4L0P , 4M4R | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 228 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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