Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1942
Gene name Gene Name - the full gene name approved by the HGNC.	Ephrin A1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	EFNA1
Synonyms (NCBI Gene) Gene synonyms aliases	B61, ECKLG, EFL1, EPLG1, GMAN, LERK-1, LERK1, TNFAIP4
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q22
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001058	hsa-miR-218-5p	qRT-PCR, Western blot	17998940
MIRT016724	hsa-miR-335-5p	Microarray	18185580
MIRT021322	hsa-miR-9-5p	Microarray	17612493
MIRT022145	hsa-miR-124-3p	Microarray	18668037
MIRT053497	hsa-miR-200c-3p	Luciferase reporter assay, qRT-PCR	23065816
MIRT477659	hsa-miR-548an	PAR-CLIP	23592263
MIRT477658	hsa-miR-6768-3p	PAR-CLIP	23592263
MIRT477657	hsa-miR-4484	PAR-CLIP	23592263
MIRT477656	hsa-miR-3714	PAR-CLIP	23592263
MIRT477655	hsa-miR-3169	PAR-CLIP	23592263
MIRT477654	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT477652	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT477653	hsa-miR-940	PAR-CLIP	23592263
MIRT477651	hsa-miR-4790-3p	PAR-CLIP	23592263
MIRT477650	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT477649	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT477648	hsa-miR-3153	PAR-CLIP	23592263
MIRT477647	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT477646	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT477645	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT477644	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT477643	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT477642	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT477640	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT477641	hsa-miR-619-3p	PAR-CLIP	23592263
MIRT477639	hsa-miR-7851-3p	PAR-CLIP	23592263
MIRT059816	hsa-miR-3123	PAR-CLIP	23592263
MIRT059819	hsa-miR-2392	PAR-CLIP	23592263
MIRT477638	hsa-miR-512-3p	PAR-CLIP	23592263
MIRT059824	hsa-miR-6871-5p	PAR-CLIP	23592263
MIRT477637	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT059814	hsa-miR-1283	PAR-CLIP	23592263
MIRT477636	hsa-miR-1913	PAR-CLIP	23592263
MIRT477635	hsa-miR-324-3p	PAR-CLIP	23592263
MIRT059821	hsa-miR-4794	PAR-CLIP	23592263
MIRT059815	hsa-miR-664a-5p	PAR-CLIP	23592263
MIRT477634	hsa-miR-4667-5p	PAR-CLIP	23592263
MIRT477633	hsa-miR-4700-5p	PAR-CLIP	23592263
MIRT477632	hsa-miR-8089	PAR-CLIP	23592263
MIRT477631	hsa-miR-637	PAR-CLIP	23592263
MIRT477630	hsa-miR-7155-5p	PAR-CLIP	23592263
MIRT477629	hsa-miR-5699-5p	PAR-CLIP	23592263
MIRT477628	hsa-miR-4758-3p	PAR-CLIP	23592263
MIRT477627	hsa-miR-3189-5p	PAR-CLIP	23592263
MIRT059809	hsa-miR-187-5p	PAR-CLIP	23592263
MIRT477626	hsa-miR-6882-3p	PAR-CLIP	23592263
MIRT059811	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT059817	hsa-miR-4306	PAR-CLIP	23592263
MIRT059820	hsa-miR-4644	PAR-CLIP	23592263
MIRT477625	hsa-miR-504-3p	PAR-CLIP	23592263
MIRT477624	hsa-miR-3175	PAR-CLIP	23592263
MIRT477623	hsa-miR-1343-5p	PAR-CLIP	23592263
MIRT477622	hsa-miR-939-5p	PAR-CLIP	23592263
MIRT477621	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT059812	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT059808	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT059823	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT477620	hsa-miR-3150a-3p	PAR-CLIP	23592263
MIRT477619	hsa-miR-6763-5p	PAR-CLIP	23592263
MIRT059814	hsa-miR-1283	PAR-CLIP	26701625
MIRT059814	hsa-miR-1283	PAR-CLIP	26701625
MIRT059814	hsa-miR-1283	PAR-CLIP	26701625
MIRT059811	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT059811	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT059811	hsa-miR-185-5p	PAR-CLIP	26701625
MIRT059809	hsa-miR-187-5p	PAR-CLIP	26701625
MIRT059809	hsa-miR-187-5p	PAR-CLIP	26701625
MIRT059809	hsa-miR-187-5p	PAR-CLIP	26701625
MIRT059819	hsa-miR-2392	PAR-CLIP	26701625
MIRT059819	hsa-miR-2392	PAR-CLIP	26701625
MIRT059819	hsa-miR-2392	PAR-CLIP	26701625
MIRT059812	hsa-miR-30c-1-3p	PAR-CLIP	26701625
MIRT059812	hsa-miR-30c-1-3p	PAR-CLIP	26701625
MIRT059812	hsa-miR-30c-1-3p	PAR-CLIP	26701625
MIRT059808	hsa-miR-30c-2-3p	PAR-CLIP	26701625
MIRT059808	hsa-miR-30c-2-3p	PAR-CLIP	26701625
MIRT059808	hsa-miR-30c-2-3p	PAR-CLIP	26701625
MIRT059816	hsa-miR-3123	PAR-CLIP	26701625
MIRT059816	hsa-miR-3123	PAR-CLIP	26701625
MIRT059816	hsa-miR-3123	PAR-CLIP	26701625
MIRT477627	hsa-miR-3189-5p	PAR-CLIP	26701625
MIRT477627	hsa-miR-3189-5p	PAR-CLIP	26701625
MIRT477627	hsa-miR-3189-5p	PAR-CLIP	26701625
MIRT059817	hsa-miR-4306	PAR-CLIP	26701625
MIRT059817	hsa-miR-4306	PAR-CLIP	26701625
MIRT059817	hsa-miR-4306	PAR-CLIP	26701625
MIRT059820	hsa-miR-4644	PAR-CLIP	26701625
MIRT059820	hsa-miR-4644	PAR-CLIP	26701625
MIRT059820	hsa-miR-4644	PAR-CLIP	26701625
MIRT477628	hsa-miR-4758-3p	PAR-CLIP	26701625
MIRT477628	hsa-miR-4758-3p	PAR-CLIP	26701625
MIRT477628	hsa-miR-4758-3p	PAR-CLIP	26701625
MIRT059821	hsa-miR-4794	PAR-CLIP	26701625
MIRT059821	hsa-miR-4794	PAR-CLIP	26701625
MIRT059821	hsa-miR-4794	PAR-CLIP	26701625
MIRT477629	hsa-miR-5699-5p	PAR-CLIP	26701625
MIRT477629	hsa-miR-5699-5p	PAR-CLIP	26701625
MIRT477629	hsa-miR-5699-5p	PAR-CLIP	26701625
MIRT477641	hsa-miR-619-3p	PAR-CLIP	26701625
MIRT477641	hsa-miR-619-3p	PAR-CLIP	26701625
MIRT477641	hsa-miR-619-3p	PAR-CLIP	26701625
MIRT059815	hsa-miR-664a-5p	PAR-CLIP	26701625
MIRT059815	hsa-miR-664a-5p	PAR-CLIP	26701625
MIRT059815	hsa-miR-664a-5p	PAR-CLIP	26701625
MIRT059823	hsa-miR-6788-5p	PAR-CLIP	26701625
MIRT059823	hsa-miR-6788-5p	PAR-CLIP	26701625
MIRT059823	hsa-miR-6788-5p	PAR-CLIP	26701625
MIRT477637	hsa-miR-6840-3p	PAR-CLIP	26701625
MIRT477637	hsa-miR-6840-3p	PAR-CLIP	26701625
MIRT477637	hsa-miR-6840-3p	PAR-CLIP	26701625
MIRT059824	hsa-miR-6871-5p	PAR-CLIP	26701625
MIRT059824	hsa-miR-6871-5p	PAR-CLIP	26701625
MIRT059824	hsa-miR-6871-5p	PAR-CLIP	26701625
MIRT477639	hsa-miR-7851-3p	PAR-CLIP	26701625
MIRT477639	hsa-miR-7851-3p	PAR-CLIP	26701625
MIRT477639	hsa-miR-7851-3p	PAR-CLIP	26701625
MIRT477659	hsa-miR-548an	PAR-CLIP	23592263
MIRT477658	hsa-miR-6768-3p	PAR-CLIP	23592263
MIRT477657	hsa-miR-4484	PAR-CLIP	23592263
MIRT477656	hsa-miR-3714	PAR-CLIP	23592263
MIRT477655	hsa-miR-3169	PAR-CLIP	23592263
MIRT477654	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT477652	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT477653	hsa-miR-940	PAR-CLIP	23592263
MIRT477651	hsa-miR-4790-3p	PAR-CLIP	23592263
MIRT477650	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT477649	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT477648	hsa-miR-3153	PAR-CLIP	23592263
MIRT477647	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT477646	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT477645	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT477644	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT477643	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT477642	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT477640	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT477641	hsa-miR-619-3p	PAR-CLIP	23592263
MIRT477639	hsa-miR-7851-3p	PAR-CLIP	23592263
MIRT059816	hsa-miR-3123	PAR-CLIP	23592263
MIRT059819	hsa-miR-2392	PAR-CLIP	23592263
MIRT477638	hsa-miR-512-3p	PAR-CLIP	23592263
MIRT059824	hsa-miR-6871-5p	PAR-CLIP	23592263
MIRT477637	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT059814	hsa-miR-1283	PAR-CLIP	23592263
MIRT477636	hsa-miR-1913	PAR-CLIP	23592263
MIRT477635	hsa-miR-324-3p	PAR-CLIP	23592263
MIRT059821	hsa-miR-4794	PAR-CLIP	23592263
MIRT059815	hsa-miR-664a-5p	PAR-CLIP	23592263
MIRT477634	hsa-miR-4667-5p	PAR-CLIP	23592263
MIRT477633	hsa-miR-4700-5p	PAR-CLIP	23592263
MIRT477632	hsa-miR-8089	PAR-CLIP	23592263
MIRT477631	hsa-miR-637	PAR-CLIP	23592263
MIRT477630	hsa-miR-7155-5p	PAR-CLIP	23592263
MIRT477629	hsa-miR-5699-5p	PAR-CLIP	23592263
MIRT477628	hsa-miR-4758-3p	PAR-CLIP	23592263
MIRT477627	hsa-miR-3189-5p	PAR-CLIP	23592263
MIRT059809	hsa-miR-187-5p	PAR-CLIP	23592263
MIRT477626	hsa-miR-6882-3p	PAR-CLIP	23592263
MIRT059811	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT059817	hsa-miR-4306	PAR-CLIP	23592263
MIRT059820	hsa-miR-4644	PAR-CLIP	23592263
MIRT477625	hsa-miR-504-3p	PAR-CLIP	23592263
MIRT477624	hsa-miR-3175	PAR-CLIP	23592263
MIRT477623	hsa-miR-1343-5p	PAR-CLIP	23592263
MIRT477622	hsa-miR-939-5p	PAR-CLIP	23592263
MIRT477621	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT059812	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT059808	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT059823	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT477620	hsa-miR-3150a-3p	PAR-CLIP	23592263
MIRT477619	hsa-miR-6763-5p	PAR-CLIP	23592263
MIRT953918	hsa-miR-1304	CLIP-seq
MIRT953919	hsa-miR-140-5p	CLIP-seq
MIRT953920	hsa-miR-185	CLIP-seq
MIRT953921	hsa-miR-1915	CLIP-seq
MIRT953922	hsa-miR-2052	CLIP-seq
MIRT953923	hsa-miR-21	CLIP-seq
MIRT953924	hsa-miR-2467-5p	CLIP-seq
MIRT953925	hsa-miR-2682	CLIP-seq
MIRT953926	hsa-miR-3120-3p	CLIP-seq
MIRT953927	hsa-miR-3188	CLIP-seq
MIRT953928	hsa-miR-326	CLIP-seq
MIRT953929	hsa-miR-330-5p	CLIP-seq
MIRT953930	hsa-miR-3975	CLIP-seq
MIRT953931	hsa-miR-4436a	CLIP-seq
MIRT953932	hsa-miR-449c	CLIP-seq
MIRT953933	hsa-miR-4633-5p	CLIP-seq
MIRT953934	hsa-miR-4643	CLIP-seq
MIRT953935	hsa-miR-466	CLIP-seq
MIRT953936	hsa-miR-4717-3p	CLIP-seq
MIRT953937	hsa-miR-4726-3p	CLIP-seq
MIRT953938	hsa-miR-4789-3p	CLIP-seq
MIRT953939	hsa-miR-485-5p	CLIP-seq
MIRT953940	hsa-miR-532-5p	CLIP-seq
MIRT953941	hsa-miR-541	CLIP-seq
MIRT953942	hsa-miR-590-5p	CLIP-seq
MIRT953943	hsa-miR-600	CLIP-seq
MIRT953944	hsa-miR-619	CLIP-seq
MIRT953945	hsa-miR-645	CLIP-seq
MIRT953946	hsa-miR-891b	CLIP-seq
MIRT953947	hsa-miR-938	CLIP-seq
MIRT953948	hsa-miR-939	CLIP-seq
MIRT953949	hsa-miR-1245b-3p	CLIP-seq
MIRT953950	hsa-miR-1271	CLIP-seq
MIRT953951	hsa-miR-1284	CLIP-seq
MIRT953952	hsa-miR-1291	CLIP-seq
MIRT953953	hsa-miR-200b	CLIP-seq
MIRT953954	hsa-miR-200c	CLIP-seq
MIRT953955	hsa-miR-2115	CLIP-seq
MIRT953925	hsa-miR-2682	CLIP-seq
MIRT953956	hsa-miR-296-5p	CLIP-seq
MIRT953926	hsa-miR-3120-3p	CLIP-seq
MIRT953957	hsa-miR-3156-3p	CLIP-seq
MIRT953958	hsa-miR-3173-5p	CLIP-seq
MIRT953959	hsa-miR-3192	CLIP-seq
MIRT953960	hsa-miR-3667-3p	CLIP-seq
MIRT953961	hsa-miR-3688-5p	CLIP-seq
MIRT953962	hsa-miR-370	CLIP-seq
MIRT953963	hsa-miR-374c	CLIP-seq
MIRT953964	hsa-miR-3943	CLIP-seq
MIRT953965	hsa-miR-3944-3p	CLIP-seq
MIRT953966	hsa-miR-4267	CLIP-seq
MIRT953967	hsa-miR-429	CLIP-seq
MIRT953968	hsa-miR-4301	CLIP-seq
MIRT953969	hsa-miR-431	CLIP-seq
MIRT953970	hsa-miR-4492	CLIP-seq
MIRT953971	hsa-miR-4498	CLIP-seq
MIRT953932	hsa-miR-449c	CLIP-seq
MIRT953972	hsa-miR-4511	CLIP-seq
MIRT953973	hsa-miR-451b	CLIP-seq
MIRT953974	hsa-miR-452	CLIP-seq
MIRT953975	hsa-miR-4660	CLIP-seq
MIRT953976	hsa-miR-4664-3p	CLIP-seq
MIRT953977	hsa-miR-4676-3p	CLIP-seq
MIRT953978	hsa-miR-4708-5p	CLIP-seq
MIRT953979	hsa-miR-4731-5p	CLIP-seq
MIRT953980	hsa-miR-4738-3p	CLIP-seq
MIRT953981	hsa-miR-4757-5p	CLIP-seq
MIRT953982	hsa-miR-4773	CLIP-seq
MIRT953983	hsa-miR-4789-5p	CLIP-seq
MIRT953984	hsa-miR-532-3p	CLIP-seq
MIRT953985	hsa-miR-548b-3p	CLIP-seq
MIRT953986	hsa-miR-548g	CLIP-seq
MIRT953987	hsa-miR-550a	CLIP-seq
MIRT953988	hsa-miR-570	CLIP-seq
MIRT953989	hsa-miR-578	CLIP-seq
MIRT953944	hsa-miR-619	CLIP-seq
MIRT953945	hsa-miR-645	CLIP-seq
MIRT953990	hsa-miR-655	CLIP-seq
MIRT953991	hsa-miR-671-3p	CLIP-seq
MIRT953992	hsa-miR-762	CLIP-seq
MIRT953993	hsa-miR-885-3p	CLIP-seq
MIRT953946	hsa-miR-891b	CLIP-seq
MIRT953947	hsa-miR-938	CLIP-seq
MIRT953994	hsa-miR-942	CLIP-seq
MIRT953995	hsa-miR-96	CLIP-seq
MIRT953951	hsa-miR-1284	CLIP-seq
MIRT1982463	hsa-miR-1285	CLIP-seq
MIRT953919	hsa-miR-140-5p	CLIP-seq
MIRT1982464	hsa-miR-145	CLIP-seq
MIRT953921	hsa-miR-1915	CLIP-seq
MIRT1982465	hsa-miR-205	CLIP-seq
MIRT953923	hsa-miR-21	CLIP-seq
MIRT1982466	hsa-miR-223	CLIP-seq
MIRT953926	hsa-miR-3120-3p	CLIP-seq
MIRT1982467	hsa-miR-3187-5p	CLIP-seq
MIRT953959	hsa-miR-3192	CLIP-seq
MIRT953928	hsa-miR-326	CLIP-seq
MIRT953929	hsa-miR-330-5p	CLIP-seq
MIRT953960	hsa-miR-3667-3p	CLIP-seq
MIRT1982468	hsa-miR-3674	CLIP-seq
MIRT953962	hsa-miR-370	CLIP-seq
MIRT1982469	hsa-miR-378g	CLIP-seq
MIRT1982470	hsa-miR-3925-3p	CLIP-seq
MIRT953964	hsa-miR-3943	CLIP-seq
MIRT1982471	hsa-miR-3945	CLIP-seq
MIRT1982472	hsa-miR-4253	CLIP-seq
MIRT1982473	hsa-miR-4277	CLIP-seq
MIRT1982474	hsa-miR-4283	CLIP-seq
MIRT953969	hsa-miR-431	CLIP-seq
MIRT953931	hsa-miR-4436a	CLIP-seq
MIRT1982475	hsa-miR-4446-3p	CLIP-seq
MIRT1982476	hsa-miR-4486	CLIP-seq
MIRT1982477	hsa-miR-4488	CLIP-seq
MIRT953970	hsa-miR-4492	CLIP-seq
MIRT953971	hsa-miR-4498	CLIP-seq
MIRT1982478	hsa-miR-4505	CLIP-seq
MIRT953933	hsa-miR-4633-5p	CLIP-seq
MIRT953976	hsa-miR-4664-3p	CLIP-seq
MIRT1982479	hsa-miR-4685-5p	CLIP-seq
MIRT1982480	hsa-miR-4697-5p	CLIP-seq
MIRT1982481	hsa-miR-4704-3p	CLIP-seq
MIRT953978	hsa-miR-4708-5p	CLIP-seq
MIRT953937	hsa-miR-4726-3p	CLIP-seq
MIRT953979	hsa-miR-4731-5p	CLIP-seq
MIRT953981	hsa-miR-4757-5p	CLIP-seq
MIRT1982482	hsa-miR-4766-5p	CLIP-seq
MIRT953983	hsa-miR-4789-5p	CLIP-seq
MIRT1982483	hsa-miR-4796-3p	CLIP-seq
MIRT1982484	hsa-miR-508-5p	CLIP-seq
MIRT953940	hsa-miR-532-5p	CLIP-seq
MIRT953941	hsa-miR-541	CLIP-seq
MIRT1982485	hsa-miR-548ae	CLIP-seq
MIRT1982486	hsa-miR-548aj	CLIP-seq
MIRT1982487	hsa-miR-548am	CLIP-seq
MIRT1982488	hsa-miR-548x	CLIP-seq
MIRT953942	hsa-miR-590-5p	CLIP-seq
MIRT1982489	hsa-miR-612	CLIP-seq
MIRT1982490	hsa-miR-663b	CLIP-seq
MIRT953991	hsa-miR-671-3p	CLIP-seq
MIRT1982491	hsa-miR-760	CLIP-seq
MIRT953992	hsa-miR-762	CLIP-seq
MIRT953946	hsa-miR-891b	CLIP-seq
MIRT953947	hsa-miR-938	CLIP-seq
MIRT953948	hsa-miR-939	CLIP-seq
MIRT953949	hsa-miR-1245b-3p	CLIP-seq
MIRT953951	hsa-miR-1284	CLIP-seq
MIRT1982463	hsa-miR-1285	CLIP-seq
MIRT953952	hsa-miR-1291	CLIP-seq
MIRT2217355	hsa-miR-183	CLIP-seq
MIRT2217356	hsa-miR-1976	CLIP-seq
MIRT1982465	hsa-miR-205	CLIP-seq
MIRT1982466	hsa-miR-223	CLIP-seq
MIRT953925	hsa-miR-2682	CLIP-seq
MIRT953956	hsa-miR-296-5p	CLIP-seq
MIRT953958	hsa-miR-3173-5p	CLIP-seq
MIRT1982467	hsa-miR-3187-5p	CLIP-seq
MIRT953959	hsa-miR-3192	CLIP-seq
MIRT953960	hsa-miR-3667-3p	CLIP-seq
MIRT953961	hsa-miR-3688-5p	CLIP-seq
MIRT2217357	hsa-miR-3690	CLIP-seq
MIRT1982469	hsa-miR-378g	CLIP-seq
MIRT2217358	hsa-miR-3934	CLIP-seq
MIRT953965	hsa-miR-3944-3p	CLIP-seq
MIRT1982471	hsa-miR-3945	CLIP-seq
MIRT1982472	hsa-miR-4253	CLIP-seq
MIRT2217359	hsa-miR-4254	CLIP-seq
MIRT1982473	hsa-miR-4277	CLIP-seq
MIRT953969	hsa-miR-431	CLIP-seq
MIRT1982476	hsa-miR-4486	CLIP-seq
MIRT953970	hsa-miR-4492	CLIP-seq
MIRT953971	hsa-miR-4498	CLIP-seq
MIRT953932	hsa-miR-449c	CLIP-seq
MIRT953934	hsa-miR-4643	CLIP-seq
MIRT953935	hsa-miR-466	CLIP-seq
MIRT953975	hsa-miR-4660	CLIP-seq
MIRT953976	hsa-miR-4664-3p	CLIP-seq
MIRT1982481	hsa-miR-4704-3p	CLIP-seq
MIRT953936	hsa-miR-4717-3p	CLIP-seq
MIRT953979	hsa-miR-4731-5p	CLIP-seq
MIRT2217360	hsa-miR-4753-5p	CLIP-seq
MIRT953981	hsa-miR-4757-5p	CLIP-seq
MIRT953938	hsa-miR-4789-3p	CLIP-seq
MIRT953983	hsa-miR-4789-5p	CLIP-seq
MIRT1982489	hsa-miR-612	CLIP-seq
MIRT2217361	hsa-miR-644	CLIP-seq
MIRT953945	hsa-miR-645	CLIP-seq
MIRT953991	hsa-miR-671-3p	CLIP-seq
MIRT1982491	hsa-miR-760	CLIP-seq
MIRT953992	hsa-miR-762	CLIP-seq
MIRT953993	hsa-miR-885-3p	CLIP-seq
MIRT953947	hsa-miR-938	CLIP-seq
MIRT953994	hsa-miR-942	CLIP-seq
MIRT953947	hsa-miR-938	CLIP-seq
MIRT953951	hsa-miR-1284	CLIP-seq
MIRT953926	hsa-miR-3120-3p	CLIP-seq
MIRT953983	hsa-miR-4789-5p	CLIP-seq
MIRT953946	hsa-miR-891b	CLIP-seq
MIRT2521268	hsa-miR-1204	CLIP-seq
MIRT2521269	hsa-miR-3127-3p	CLIP-seq
MIRT953966	hsa-miR-4267	CLIP-seq
MIRT1982490	hsa-miR-663b	CLIP-seq

Show/Hide all(40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	ISS
GO:0001525	Process	Angiogenesis	IEA
GO:0001934	Process	Positive regulation of protein phosphorylation	IGI	24217950
GO:0003180	Process	Aortic valve morphogenesis	ISS
GO:0003183	Process	Mitral valve morphogenesis	ISS
GO:0003199	Process	Endocardial cushion to mesenchymal transition involved in heart valve formation	ISS
GO:0005102	Function	Signaling receptor binding	TAS	8660976
GO:0005515	Function	Protein binding	IPI	19525919, 19573808, 20505120, 22244754
GO:0005576	Component	Extracellular region	IEA
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0005886	Component	Plasma membrane	NAS	24217950
GO:0005886	Component	Plasma membrane	TAS
GO:0007267	Process	Cell-cell signaling	TAS	8660976
GO:0007411	Process	Axon guidance	IBA	21873635
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	ISS
GO:0014028	Process	Notochord formation	IEA
GO:0016477	Process	Cell migration	IDA	10655584
GO:0033628	Process	Regulation of cell adhesion mediated by integrin	IDA	10655584
GO:0034446	Process	Substrate adhesion-dependent cell spreading	IDA	10655584
GO:0043409	Process	Negative regulation of MAPK cascade	IEA
GO:0043410	Process	Positive regulation of MAPK cascade	IEA
GO:0043535	Process	Regulation of blood vessel endothelial cell migration	IEA
GO:0045765	Process	Regulation of angiogenesis	IEA
GO:0046658	Component	Anchored component of plasma membrane	IBA	21873635
GO:0046875	Function	Ephrin receptor binding	IBA	21873635
GO:0046875	Function	Ephrin receptor binding	IPI	11519828, 15777695
GO:0048013	Process	Ephrin receptor signaling pathway	IBA	21873635
GO:0048013	Process	Ephrin receptor signaling pathway	IDA	10655584
GO:0048013	Process	Ephrin receptor signaling pathway	IGI	24217950
GO:0048013	Process	Ephrin receptor signaling pathway	TAS
GO:0050730	Process	Regulation of peptidyl-tyrosine phosphorylation	ISS
GO:0050731	Process	Positive regulation of peptidyl-tyrosine phosphorylation	IDA	10655584
GO:0050770	Process	Regulation of axonogenesis	IEA
GO:0050821	Process	Protein stabilization	IGI	24217950
GO:0061002	Process	Negative regulation of dendritic spine morphogenesis	ISS
GO:0061098	Process	Positive regulation of protein tyrosine kinase activity	IGI	24217950
GO:0070244	Process	Negative regulation of thymocyte apoptotic process	IEA
GO:1902004	Process	Positive regulation of amyloid-beta formation	IDA	24217950
GO:1902961	Process	Positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	IGI	24217950
GO:1903051	Process	Negative regulation of proteolysis involved in cellular protein catabolic process	IGI	24217950

MIM	HGNC	e!Ensembl
191164	3221	ENSG00000169242

Protein

UniProt ID

P20827

Protein name

Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]

Protein function

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on ad

PDB

3CZU , 3HEI , 3MBW

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00812	Ephrin	18 → 147	Ephrin	Domain

Tissue specificity

TISSUE SPECIFICITY: Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level). {ECO:0000269|PubMed:17332925}.

Sequence

MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVA
DAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEF
KEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIG
HSAAPRLFPLAWTVLLLPLLLLQTP

Sequence length

205

Interactions

View interactions

	KEGG		Reactome
	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway PI3K-Akt signaling pathway Axon guidance MicroRNAs in cancer		EPH-Ephrin signaling EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)	20154726
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	20154726
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465 View all (942 more)	20154726

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Prostate cancer	Prostate cancer	Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population.		GWAS, CBGDA

Show/Hide Text Mining Associations (54)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	22853000
Adenocarcinoma	Stimulate	34087884
Adenocarcinoma of Lung	Associate	22807579
Allergic Fungal Sinusitis	Associate	34975898
Breast Neoplasms	Inhibit	15649254
Breast Neoplasms	Associate	18794797, 21935409, 22261062, 26861043, 33977106
Carcinoma Hepatocellular	Associate	15888795
Carcinoma Non Small Cell Lung	Associate	22853000, 24293999
Carcinoma Renal Cell	Associate	25025847
Carcinoma Squamous Cell	Associate	17158642, 18566674, 24040255
Carcinoma Squamous Cell	Stimulate	34087884
Cerebral Infarction	Associate	31077198
Colitis Ulcerative	Associate	37055577
Colonic Neoplasms	Associate	21479221
Colorectal Neoplasms	Stimulate	24175772, 34700376
Colorectal Neoplasms	Associate	24175772, 36308379, 36401637, 40004552
Developmental Dysplasia of the Hip	Associate	33522290
Diabetic Retinopathy	Associate	32758187
Esophageal Neoplasms	Stimulate	34087884, 34399788
Esophageal Squamous Cell Carcinoma	Associate	16080548, 31485619
Esophageal Squamous Cell Carcinoma	Stimulate	37774793
Glioblastoma	Associate	16254188, 18794797, 22688511
Glioma	Associate	16254188, 34087884
Glioma	Inhibit	19573808
Head and Neck Neoplasms	Associate	24330498, 34344926
Hematologic Diseases	Associate	36901860
Hypoxia	Stimulate	24040255
Hypoxia Brain	Stimulate	24040255
Idiopathic Noncirrhotic Portal Hypertension	Stimulate	15888795
Leprosy	Associate	36142557
Leukemia	Associate	20061560
Lung Neoplasms	Associate	24293999
Lymphatic Metastasis	Associate	34399788
Lymphoma Non Hodgkin	Associate	34087884
Medulloblastoma	Associate	25258252
Melanoma	Associate	11891198
Mesothelioma Malignant	Associate	24293999
Multiple Sclerosis	Associate	15779235
Neoplasm Metastasis	Associate	15888795, 24215488, 36308379
Neoplasms	Associate	11891198, 14965363, 15649254, 16080548, 17041885, 18794797, 22688511, 23158542, 24040255, 24330498, 25025847, 28585531, 33977106, 34087884, 34399788
Neoplasms	Inhibit	22362770, 22824143, 23238013, 24293999
Neoplasms Squamous Cell	Associate	34642392
Osteoarthritis Hip	Associate	33522290
Osteosarcoma	Associate	12209731
Prostatic Neoplasms	Inhibit	19573808
Prostatic Neoplasms	Associate	22075945
Prostatitis	Associate	17449913
Pterygium	Associate	16446702
Rectal Diseases	Stimulate	23158542
Rectal Neoplasms	Associate	18959792, 40004552
Stomach Neoplasms	Associate	15649254
Stomach Neoplasms	Stimulate	37579183
Uterine Cervical Neoplasms	Associate	18566674
Vulvar Neoplasms	Associate	17158642

EFNA1 (ephrin A1)