DSC3 (desmocollin 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 1825 |
| Gene name | Desmocollin 3 |
| Gene symbol | DSC3 |
| Synonyms (NCBI Gene) |
CDHF3DSCDSC1DSC2DSC4HT-CP
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| Chromosome | 18 |
| Chromosome location | 18q12.1 |
| Summary | The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
257
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q14574 | |||||||||||||||||||||||||||||||||||
| Protein name | Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP) | |||||||||||||||||||||||||||||||||||
| Protein function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and t | |||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed throughout the basal and spinous layer of the epidermis with weak expression in the granular layer (at protein level) (PubMed:19717567, PubMed:7665906). Also expressed in the buccal mucosa, esophagus and cervix (at protein le | |||||||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 896 | |||||||||||||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
20
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