TRDMT1 (tRNA aspartic acid methyltransferase 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 1787 |
| Gene name | TRNA aspartic acid methyltransferase 1 |
| Gene symbol | TRDMT1 |
| Synonyms (NCBI Gene) |
DMNT2DNMT2MHSAIIPPUMETRNMT1
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| Chromosome | 10 |
| Chromosome location | 10p13 |
| Summary | This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in se |
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miRNA
miRNA information provided by mirtarbase database.
405
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O14717 | ||||||||||
| Protein name | tRNA (cytosine(38)-C(5))-methyltransferase (EC 2.1.1.204) (DNA (cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet) | ||||||||||
| Protein function | Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (PubMed:16424344). Has higher activity on tRNA(Asp) modified with queuosine at position 34 (PubMed:30093495). | ||||||||||
| PDB | 1G55 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes. | ||||||||||
| Sequence |
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| Sequence length | 391 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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