DBN1 (drebrin 1)

Gene

• Entrez ID: 1627
• Gene name: Drebrin 1
• Gene symbol: DBN1
• Synonyms (NCBI Gene): D0S117E
• Chromosome: 5
• Chromosome location: 5q35.3
• Summary: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020934	hsa-miR-155-5p	Proteomics	18668040
MIRT024053	hsa-miR-1-3p	Proteomics	18668040
MIRT024053	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT046733	hsa-miR-222-3p	CLASH	23622248
MIRT045543	hsa-miR-149-5p	CLASH	23622248
MIRT045157	hsa-miR-186-5p	CLASH	23622248
MIRT040871	hsa-miR-18a-3p	CLASH	23622248
MIRT039919	hsa-miR-615-3p	CLASH	23622248
MIRT037119	hsa-miR-877-3p	CLASH	23622248
MIRT558490	hsa-miR-137	HITS-CLIP	21572407
MIRT558488	hsa-miR-4282	HITS-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	HITS-CLIP	21572407
MIRT558486	hsa-miR-4307	HITS-CLIP	21572407
MIRT558487	hsa-miR-4729	HITS-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	HITS-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	HITS-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	HITS-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	HITS-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	HITS-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	HITS-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	HITS-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	HITS-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	HITS-CLIP	21572407
MIRT558492	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT558491	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT558490	hsa-miR-137	PAR-CLIP	21572407
MIRT558488	hsa-miR-4282	PAR-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT558486	hsa-miR-4307	PAR-CLIP	21572407
MIRT558487	hsa-miR-4729	PAR-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	PAR-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	PAR-CLIP	21572407
MIRT558483	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT558482	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT558481	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT558480	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT558479	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	PAR-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	PAR-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	PAR-CLIP	21572407
MIRT558475	hsa-miR-548aw	PAR-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	PAR-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	PAR-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	PAR-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	PAR-CLIP	21572407
MIRT538201	hsa-miR-483-3p	PAR-CLIP	22012620
MIRT538200	hsa-miR-5195-5p	PAR-CLIP	22012620
MIRT538199	hsa-miR-5193	PAR-CLIP	22012620
MIRT538198	hsa-miR-660-3p	PAR-CLIP	22012620
MIRT538197	hsa-miR-1914-5p	PAR-CLIP	22012620
MIRT538196	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT538195	hsa-miR-4679	PAR-CLIP	22012620
MIRT538194	hsa-miR-548ao-5p	PAR-CLIP	22012620
MIRT538193	hsa-miR-548ax	PAR-CLIP	22012620
MIRT538192	hsa-miR-5585-5p	PAR-CLIP	22012620
MIRT538191	hsa-miR-4513	PAR-CLIP	22012620
MIRT538190	hsa-miR-6855-3p	PAR-CLIP	22012620
MIRT538189	hsa-miR-6857-3p	PAR-CLIP	22012620
MIRT538188	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT538187	hsa-miR-3136-5p	PAR-CLIP	22012620
MIRT538186	hsa-miR-4439	PAR-CLIP	22012620
MIRT538185	hsa-miR-943	PAR-CLIP	22012620
MIRT538184	hsa-miR-8070	PAR-CLIP	22012620
MIRT538183	hsa-miR-4675	PAR-CLIP	22012620
MIRT558490	hsa-miR-137	HITS-CLIP	21572407
MIRT558488	hsa-miR-4282	HITS-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	HITS-CLIP	21572407
MIRT558486	hsa-miR-4307	HITS-CLIP	21572407
MIRT558487	hsa-miR-4729	HITS-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	HITS-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	HITS-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	HITS-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	HITS-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	HITS-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	HITS-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	HITS-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	HITS-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	HITS-CLIP	21572407
MIRT558492	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT558491	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT558490	hsa-miR-137	PAR-CLIP	21572407
MIRT558488	hsa-miR-4282	PAR-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT558486	hsa-miR-4307	PAR-CLIP	21572407
MIRT558487	hsa-miR-4729	PAR-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	PAR-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	PAR-CLIP	21572407
MIRT558483	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT558482	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT558481	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT558480	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT558479	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	PAR-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	PAR-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	PAR-CLIP	21572407
MIRT558475	hsa-miR-548aw	PAR-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	PAR-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	PAR-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	PAR-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	PAR-CLIP	21572407
MIRT538201	hsa-miR-483-3p	PAR-CLIP	22012620
MIRT538200	hsa-miR-5195-5p	PAR-CLIP	22012620
MIRT538199	hsa-miR-5193	PAR-CLIP	22012620
MIRT538198	hsa-miR-660-3p	PAR-CLIP	22012620
MIRT538197	hsa-miR-1914-5p	PAR-CLIP	22012620
MIRT538196	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT538195	hsa-miR-4679	PAR-CLIP	22012620
MIRT538194	hsa-miR-548ao-5p	PAR-CLIP	22012620
MIRT538193	hsa-miR-548ax	PAR-CLIP	22012620
MIRT538192	hsa-miR-5585-5p	PAR-CLIP	22012620
MIRT538191	hsa-miR-4513	PAR-CLIP	22012620
MIRT538190	hsa-miR-6855-3p	PAR-CLIP	22012620
MIRT538189	hsa-miR-6857-3p	PAR-CLIP	22012620
MIRT538188	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT538187	hsa-miR-3136-5p	PAR-CLIP	22012620
MIRT538186	hsa-miR-4439	PAR-CLIP	22012620
MIRT538185	hsa-miR-943	PAR-CLIP	22012620
MIRT538184	hsa-miR-8070	PAR-CLIP	22012620
MIRT538183	hsa-miR-4675	PAR-CLIP	22012620
MIRT923758	hsa-miR-103b	CLIP-seq
MIRT923759	hsa-miR-1203	CLIP-seq
MIRT923760	hsa-miR-1207-3p	CLIP-seq
MIRT923761	hsa-miR-1224-3p	CLIP-seq
MIRT923762	hsa-miR-1260	CLIP-seq
MIRT923763	hsa-miR-1260b	CLIP-seq
MIRT923764	hsa-miR-1275	CLIP-seq
MIRT923765	hsa-miR-1280	CLIP-seq
MIRT923766	hsa-miR-1290	CLIP-seq
MIRT923767	hsa-miR-1291	CLIP-seq
MIRT923768	hsa-miR-129-3p	CLIP-seq
MIRT923769	hsa-miR-146b-3p	CLIP-seq
MIRT923770	hsa-miR-182	CLIP-seq
MIRT923771	hsa-miR-188-3p	CLIP-seq
MIRT923772	hsa-miR-1908	CLIP-seq
MIRT923773	hsa-miR-1915	CLIP-seq
MIRT923774	hsa-miR-1972	CLIP-seq
MIRT923775	hsa-miR-19a	CLIP-seq
MIRT923776	hsa-miR-19b	CLIP-seq
MIRT923777	hsa-miR-2110	CLIP-seq
MIRT923778	hsa-miR-2113	CLIP-seq
MIRT923779	hsa-miR-2355-5p	CLIP-seq
MIRT923780	hsa-miR-2861	CLIP-seq
MIRT923781	hsa-miR-296-5p	CLIP-seq
MIRT923782	hsa-miR-31	CLIP-seq
MIRT923783	hsa-miR-3121-5p	CLIP-seq
MIRT923784	hsa-miR-3123	CLIP-seq
MIRT923785	hsa-miR-3132	CLIP-seq
MIRT923786	hsa-miR-3141	CLIP-seq
MIRT923787	hsa-miR-3145-3p	CLIP-seq
MIRT923788	hsa-miR-3150a-3p	CLIP-seq
MIRT923789	hsa-miR-3154	CLIP-seq
MIRT923790	hsa-miR-3156-3p	CLIP-seq
MIRT923791	hsa-miR-3167	CLIP-seq
MIRT923792	hsa-miR-3173-3p	CLIP-seq
MIRT923793	hsa-miR-3175	CLIP-seq
MIRT923794	hsa-miR-3176	CLIP-seq
MIRT923795	hsa-miR-3177-3p	CLIP-seq
MIRT923796	hsa-miR-3184	CLIP-seq
MIRT923797	hsa-miR-3189-5p	CLIP-seq
MIRT923798	hsa-miR-3200-5p	CLIP-seq
MIRT923799	hsa-miR-320a	CLIP-seq
MIRT923800	hsa-miR-320b	CLIP-seq
MIRT923801	hsa-miR-320c	CLIP-seq
MIRT923802	hsa-miR-320d	CLIP-seq
MIRT923803	hsa-miR-331-3p	CLIP-seq
MIRT923804	hsa-miR-3607-3p	CLIP-seq
MIRT923805	hsa-miR-3609	CLIP-seq
MIRT923806	hsa-miR-3619-3p	CLIP-seq
MIRT923807	hsa-miR-3622a-5p	CLIP-seq
MIRT923808	hsa-miR-3651	CLIP-seq
MIRT923809	hsa-miR-3661	CLIP-seq
MIRT923810	hsa-miR-3663-3p	CLIP-seq
MIRT923811	hsa-miR-3665	CLIP-seq
MIRT923812	hsa-miR-3689a-5p	CLIP-seq
MIRT923813	hsa-miR-3689b	CLIP-seq
MIRT923814	hsa-miR-3689e	CLIP-seq
MIRT923815	hsa-miR-3689f	CLIP-seq
MIRT923816	hsa-miR-3690	CLIP-seq
MIRT923817	hsa-miR-3691-3p	CLIP-seq
MIRT923818	hsa-miR-378	CLIP-seq
MIRT923819	hsa-miR-378b	CLIP-seq
MIRT923820	hsa-miR-378c	CLIP-seq
MIRT923821	hsa-miR-378d	CLIP-seq
MIRT923822	hsa-miR-378e	CLIP-seq
MIRT923823	hsa-miR-378f	CLIP-seq
MIRT923824	hsa-miR-378h	CLIP-seq
MIRT923825	hsa-miR-378i	CLIP-seq
MIRT923826	hsa-miR-3918	CLIP-seq
MIRT923827	hsa-miR-3919	CLIP-seq
MIRT923828	hsa-miR-3922-3p	CLIP-seq
MIRT923829	hsa-miR-3929	CLIP-seq
MIRT923830	hsa-miR-3937	CLIP-seq
MIRT923831	hsa-miR-422a	CLIP-seq
MIRT923832	hsa-miR-423-5p	CLIP-seq
MIRT923833	hsa-miR-4259	CLIP-seq
MIRT923834	hsa-miR-4269	CLIP-seq
MIRT923835	hsa-miR-4270	CLIP-seq
MIRT923836	hsa-miR-4292	CLIP-seq
MIRT923837	hsa-miR-4308	CLIP-seq
MIRT923838	hsa-miR-4311	CLIP-seq
MIRT923839	hsa-miR-4316	CLIP-seq
MIRT923840	hsa-miR-4419b	CLIP-seq
MIRT923841	hsa-miR-4429	CLIP-seq
MIRT923842	hsa-miR-4435	CLIP-seq
MIRT923843	hsa-miR-4441	CLIP-seq
MIRT923844	hsa-miR-4446-5p	CLIP-seq
MIRT923845	hsa-miR-4447	CLIP-seq
MIRT923846	hsa-miR-4472	CLIP-seq
MIRT923847	hsa-miR-4477a	CLIP-seq
MIRT923848	hsa-miR-4478	CLIP-seq
MIRT923849	hsa-miR-4480	CLIP-seq
MIRT923850	hsa-miR-4481	CLIP-seq
MIRT923851	hsa-miR-4496	CLIP-seq
MIRT923852	hsa-miR-450b-5p	CLIP-seq
MIRT923853	hsa-miR-4520a-3p	CLIP-seq
MIRT923854	hsa-miR-4525	CLIP-seq
MIRT923855	hsa-miR-4638-3p	CLIP-seq
MIRT923856	hsa-miR-4640-5p	CLIP-seq
MIRT923857	hsa-miR-4650-5p	CLIP-seq
MIRT923858	hsa-miR-4651	CLIP-seq
MIRT923859	hsa-miR-4665-5p	CLIP-seq
MIRT923860	hsa-miR-4685-5p	CLIP-seq
MIRT923861	hsa-miR-4687-5p	CLIP-seq
MIRT923862	hsa-miR-4706	CLIP-seq
MIRT923863	hsa-miR-4710	CLIP-seq
MIRT923864	hsa-miR-4722-5p	CLIP-seq
MIRT923865	hsa-miR-4723-5p	CLIP-seq
MIRT923866	hsa-miR-4726-3p	CLIP-seq
MIRT923867	hsa-miR-4726-5p	CLIP-seq
MIRT923868	hsa-miR-4728-5p	CLIP-seq
MIRT923869	hsa-miR-4732-3p	CLIP-seq
MIRT923870	hsa-miR-4743	CLIP-seq
MIRT923871	hsa-miR-4745-5p	CLIP-seq
MIRT923872	hsa-miR-4747-5p	CLIP-seq
MIRT923873	hsa-miR-4749-5p	CLIP-seq
MIRT923874	hsa-miR-4755-3p	CLIP-seq
MIRT923875	hsa-miR-4759	CLIP-seq
MIRT923876	hsa-miR-4768-3p	CLIP-seq
MIRT923877	hsa-miR-4776-5p	CLIP-seq
MIRT923878	hsa-miR-4779	CLIP-seq
MIRT923879	hsa-miR-4786-3p	CLIP-seq
MIRT923880	hsa-miR-4803	CLIP-seq
MIRT923881	hsa-miR-483-5p	CLIP-seq
MIRT923882	hsa-miR-485-5p	CLIP-seq
MIRT923883	hsa-miR-494	CLIP-seq
MIRT923884	hsa-miR-517a	CLIP-seq
MIRT923885	hsa-miR-517b	CLIP-seq
MIRT923886	hsa-miR-517c	CLIP-seq
MIRT923887	hsa-miR-520d-5p	CLIP-seq
MIRT923888	hsa-miR-520g	CLIP-seq
MIRT923889	hsa-miR-520h	CLIP-seq
MIRT923890	hsa-miR-524-5p	CLIP-seq
MIRT923891	hsa-miR-541	CLIP-seq
MIRT923892	hsa-miR-548a-3p	CLIP-seq
MIRT923893	hsa-miR-548ah	CLIP-seq
MIRT923894	hsa-miR-548e	CLIP-seq
MIRT923895	hsa-miR-548f	CLIP-seq
MIRT923896	hsa-miR-548n	CLIP-seq
MIRT923897	hsa-miR-548t	CLIP-seq
MIRT923898	hsa-miR-558	CLIP-seq
MIRT923899	hsa-miR-564	CLIP-seq
MIRT923900	hsa-miR-571	CLIP-seq
MIRT923901	hsa-miR-608	CLIP-seq
MIRT923902	hsa-miR-615-5p	CLIP-seq
MIRT923903	hsa-miR-625	CLIP-seq
MIRT923904	hsa-miR-631	CLIP-seq
MIRT923905	hsa-miR-654-5p	CLIP-seq
MIRT923906	hsa-miR-657	CLIP-seq
MIRT923907	hsa-miR-663	CLIP-seq
MIRT923908	hsa-miR-876-5p	CLIP-seq
MIRT923909	hsa-miR-935	CLIP-seq
MIRT923910	hsa-miR-939	CLIP-seq
MIRT923794	hsa-miR-3176	CLIP-seq
MIRT923795	hsa-miR-3177-3p	CLIP-seq
MIRT923807	hsa-miR-3622a-5p	CLIP-seq
MIRT923811	hsa-miR-3665	CLIP-seq
MIRT923828	hsa-miR-3922-3p	CLIP-seq
MIRT923829	hsa-miR-3929	CLIP-seq
MIRT923834	hsa-miR-4269	CLIP-seq
MIRT923840	hsa-miR-4419b	CLIP-seq
MIRT923842	hsa-miR-4435	CLIP-seq
MIRT923848	hsa-miR-4478	CLIP-seq
MIRT923882	hsa-miR-485-5p	CLIP-seq
MIRT923891	hsa-miR-541	CLIP-seq
MIRT923899	hsa-miR-564	CLIP-seq
MIRT923905	hsa-miR-654-5p	CLIP-seq
MIRT923906	hsa-miR-657	CLIP-seq
MIRT923773	hsa-miR-1915	CLIP-seq
MIRT923835	hsa-miR-4270	CLIP-seq
MIRT923843	hsa-miR-4441	CLIP-seq
MIRT923866	hsa-miR-4726-3p	CLIP-seq
MIRT923902	hsa-miR-615-5p	CLIP-seq
MIRT923759	hsa-miR-1203	CLIP-seq
MIRT923767	hsa-miR-1291	CLIP-seq
MIRT923769	hsa-miR-146b-3p	CLIP-seq
MIRT923774	hsa-miR-1972	CLIP-seq
MIRT923779	hsa-miR-2355-5p	CLIP-seq
MIRT923785	hsa-miR-3132	CLIP-seq
MIRT923792	hsa-miR-3173-3p	CLIP-seq
MIRT923794	hsa-miR-3176	CLIP-seq
MIRT923795	hsa-miR-3177-3p	CLIP-seq
MIRT923806	hsa-miR-3619-3p	CLIP-seq
MIRT923807	hsa-miR-3622a-5p	CLIP-seq
MIRT923810	hsa-miR-3663-3p	CLIP-seq
MIRT923811	hsa-miR-3665	CLIP-seq
MIRT923817	hsa-miR-3691-3p	CLIP-seq
MIRT923818	hsa-miR-378	CLIP-seq
MIRT923819	hsa-miR-378b	CLIP-seq
MIRT923820	hsa-miR-378c	CLIP-seq
MIRT923821	hsa-miR-378d	CLIP-seq
MIRT923822	hsa-miR-378e	CLIP-seq
MIRT923823	hsa-miR-378f	CLIP-seq
MIRT923824	hsa-miR-378h	CLIP-seq
MIRT923825	hsa-miR-378i	CLIP-seq
MIRT923826	hsa-miR-3918	CLIP-seq
MIRT923828	hsa-miR-3922-3p	CLIP-seq
MIRT923829	hsa-miR-3929	CLIP-seq
MIRT923830	hsa-miR-3937	CLIP-seq
MIRT923831	hsa-miR-422a	CLIP-seq
MIRT923834	hsa-miR-4269	CLIP-seq
MIRT923835	hsa-miR-4270	CLIP-seq
MIRT923839	hsa-miR-4316	CLIP-seq
MIRT923840	hsa-miR-4419b	CLIP-seq
MIRT923842	hsa-miR-4435	CLIP-seq
MIRT923843	hsa-miR-4441	CLIP-seq
MIRT2209200	hsa-miR-4468	CLIP-seq
MIRT923848	hsa-miR-4478	CLIP-seq
MIRT923849	hsa-miR-4480	CLIP-seq
MIRT923850	hsa-miR-4481	CLIP-seq
MIRT923852	hsa-miR-450b-5p	CLIP-seq
MIRT923855	hsa-miR-4638-3p	CLIP-seq
MIRT923857	hsa-miR-4650-5p	CLIP-seq
MIRT2209201	hsa-miR-4663	CLIP-seq
MIRT923860	hsa-miR-4685-5p	CLIP-seq
MIRT923863	hsa-miR-4710	CLIP-seq
MIRT923868	hsa-miR-4728-5p	CLIP-seq
MIRT923870	hsa-miR-4743	CLIP-seq
MIRT923871	hsa-miR-4745-5p	CLIP-seq
MIRT923872	hsa-miR-4747-5p	CLIP-seq
MIRT923874	hsa-miR-4755-3p	CLIP-seq
MIRT923877	hsa-miR-4776-5p	CLIP-seq
MIRT923878	hsa-miR-4779	CLIP-seq
MIRT923882	hsa-miR-485-5p	CLIP-seq
MIRT923898	hsa-miR-558	CLIP-seq
MIRT923899	hsa-miR-564	CLIP-seq
MIRT923906	hsa-miR-657	CLIP-seq
MIRT2209202	hsa-miR-941	CLIP-seq
MIRT2386733	hsa-miR-1324	CLIP-seq
MIRT923783	hsa-miR-3121-5p	CLIP-seq
MIRT923856	hsa-miR-4640-5p	CLIP-seq
MIRT923867	hsa-miR-4726-5p	CLIP-seq
MIRT923760	hsa-miR-1207-3p	CLIP-seq
MIRT923780	hsa-miR-2861	CLIP-seq
MIRT923781	hsa-miR-296-5p	CLIP-seq
MIRT923796	hsa-miR-3184	CLIP-seq
MIRT923832	hsa-miR-423-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001701	Process	In utero embryonic development	IEA
GO:0003779	Function	Actin binding	IEA
GO:0003779	Function	Actin binding	NAS	12761245
GO:0003779	Function	Actin binding	TAS	8216329
GO:0005515	Function	Protein binding	IPI	12577067, 20215400, 21044950, 23750010, 23926103, 23940795, 25814554, 25839164, 28966017, 35916866
GO:0005522	Function	Profilin binding	ISS
GO:0005737	Component	Cytoplasm	IDA	8838578, 28966017
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	12009525
GO:0005856	Component	Cytoskeleton	IBA
GO:0005856	Component	Cytoskeleton	IDA	24327345
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005911	Component	Cell-cell junction	IEA
GO:0005921	Component	Gap junction	IEA
GO:0005938	Component	Cell cortex	IEA
GO:0007015	Process	Actin filament organization	IEA
GO:0007015	Process	Actin filament organization	ISS
GO:0007399	Process	Nervous system development	IEA
GO:0010643	Process	Cell communication by chemical coupling	IEA
GO:0010644	Process	Cell communication by electrical coupling	IEA
GO:0014069	Component	Postsynaptic density	IEA
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0015629	Component	Actin cytoskeleton	ISS
GO:0015629	Component	Actin cytoskeleton	TAS	8216329
GO:0016020	Component	Membrane	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0030425	Component	Dendrite	IDA	8838578
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	NAS	12009525
GO:0030426	Component	Growth cone	IEA
GO:0030426	Component	Growth cone	ISS
GO:0030863	Component	Cortical cytoskeleton	TAS	17251419
GO:0031915	Process	Positive regulation of synaptic plasticity	IEA
GO:0031915	Process	Positive regulation of synaptic plasticity	ISS
GO:0032507	Process	Maintenance of protein location in cell	IEA
GO:0042641	Component	Actomyosin	NAS	12761245
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0045211	Component	Postsynaptic membrane	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0048168	Process	Regulation of neuronal synaptic plasticity	NAS	12009525
GO:0048699	Process	Generation of neurons	IEA
GO:0050773	Process	Regulation of dendrite development	NAS	12009525
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	IEA
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	ISS
GO:0061351	Process	Neural precursor cell proliferation	IEA
GO:0070161	Component	Anchoring junction	IEA
GO:0071944	Component	Cell periphery	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099524	Component	Postsynaptic cytosol	IEA
GO:0140311	Function	Protein sequestering activity	IDA	28966017
GO:1902685	Process	Positive regulation of receptor localization to synapse	IEA
GO:1902685	Process	Positive regulation of receptor localization to synapse	ISS

Other IDs

• MIM: 126660
• HGNC: 2695
• e!Ensembl: ENSG00000113758

Protein

• UniProt ID: Q16643
• Protein name: Drebrin (Developmentally-regulated brain protein)
• Protein function: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMe
• PDB: 5Y1Z, 5ZZ9
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00241	Cofilin_ADF	13 → 132	Cofilin/tropomyosin-type actin-binding protein	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the brain, with expression in the molecular layer of the dentate gyrus, stratum pyramidale, and stratum radiatum of the hippocampus (at protein level) (PubMed:8838578). Also expressed in the terminal varicosities distribut
• Sequence:

  MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFEN
  QKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS
  VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQF
  WEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQ
  TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV
  ASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVT
  SSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAED
  LMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWP
  GNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPP
  ATFCDPEEVEGESLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQ
  SQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD

• Sequence length: 649