DBN1 (drebrin 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1627 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Drebrin 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DBN1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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D0S117E |
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Chromosome
Chromosome number
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5 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q35.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q16643 | ||||||||||
| Protein name | Drebrin (Developmentally-regulated brain protein) | ||||||||||
| Protein function | Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMe | ||||||||||
| PDB | 5Y1Z , 5ZZ9 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in the brain, with expression in the molecular layer of the dentate gyrus, stratum pyramidale, and stratum radiatum of the hippocampus (at protein level) (PubMed:8838578). Also expressed in the terminal varicosities distribut | ||||||||||
| Sequence |
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| Sequence length | 649 | ||||||||||
| Interactions | View interactions | ||||||||||