Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
160897
Gene name Gene Name - the full gene name approved by the HGNC.
G protein-coupled receptor 180
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GPR180
Synonyms (NCBI Gene) Gene synonyms aliases
ITR
Chromosome Chromosome number
13
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
13q32.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein that is a member of the G protein-coupled receptor superfamily. This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling. [provided by RefSeq
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024681 hsa-miR-215-5p Microarray 19074876
MIRT026775 hsa-miR-192-5p Microarray 19074876
MIRT027173 hsa-miR-103a-3p Sequencing 20371350
MIRT031916 hsa-miR-16-5p Sequencing 20371350
MIRT668067 hsa-miR-627-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0007186 Process G protein-coupled receptor signaling pathway IEA
GO:0016021 Component Integral component of membrane IEA
GO:0019236 Process Response to pheromone IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607787 28899 ENSG00000152749
Protein
UniProt ID Q86V85
Protein name Integral membrane protein GPR180 (Intimal thickness-related receptor)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10192 GpcrRhopsn4 141 405 Rhodopsin-like GPCR transmembrane domain Family
Sequence
MGGLRLLAVALTCCWWPQGSQGKTLRGSFSSTAAQDAQGQRIGHFEFHGDHALLCVRINN
IAVAVGKEAKLYLFQAQEWLKLQQSSHGYSCSEKLSKAQLTMTMNQTEHNLTVSQIPSPQ
TWHVFYADKYTCQDDKENSQVEDIPFEMVLLNPDAEGNPFDHFSAGESGLHEFFFLLVLV
YFVIACIYAQSLWQAIKKGGPMHMILKVLTTALLLQAGSALANYIHFSSYSKDGIGVPFM
GSLAEFFDIASQIQMLYLLLSLCMGWTIVRMKKSQSRPLQWDSTPASTGIAVFIVMTQSV
LLLWEQFEDISHHSYHSHHNLAGILLIVLRICLALSLGCGLYQIITVERSTLKREFYITF
AKGCILWFLCHPVLACISVIFSDYQRDKVITIGVILCQSVSMVIL
YRLFLSHSLYWEVSS
LSSVTLPLTISSGHKSRPHF
Sequence length 440
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Associations from Text Mining
Disease Name Relationship Type References
Hepatoblastoma Associate 26991471
Hypertriglyceridemia Associate 31868224
Microcoria congenital Associate 32200002
Neoplasms Inhibit 26991471
Vascular Remodeling Associate 23940718