FAAH2 (fatty acid amide hydrolase 2)

Gene
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
158584
Gene name Gene Name - the full gene name approved by the HGNC.
Fatty acid amide hydrolase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FAAH2
Synonyms (NCBI Gene) Gene synonyms aliases
AMDD
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp11.21
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three m
SNPs SNP information provided by dbSNP.
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
SNP ID Visualize variation Clinical significance Consequence
rs1555959573 CAAGTACAGGT>- Pathogenic Non coding transcript variant, coding sequence variant, splice donor variant
miRNA miRNA information provided by mirtarbase database.
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(19)
miRTarBase ID miRNA Experiments Reference
MIRT017603 hsa-miR-335-5p Microarray 18185580
MIRT2223216 hsa-miR-1231 CLIP-seq
MIRT2223217 hsa-miR-137 CLIP-seq
MIRT2223218 hsa-miR-25 CLIP-seq
MIRT2223219 hsa-miR-32 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(7)
GO ID Ontology Definition Evidence Reference
GO:0005811 Component Lipid droplet TAS
GO:0016021 Component Integral component of membrane IEA
GO:0016042 Process Lipid catabolic process IEA
GO:0017064 Function Fatty acid amide hydrolase activity TAS
GO:0019369 Process Arachidonic acid metabolic process TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
300654 26440 ENSG00000165591
Protein
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q6GMR7
Protein name Fatty-acid amide hydrolase 2 (EC 3.5.1.99) (Amidase domain-containing protein) (Anandamide amidohydrolase 2) (Oleamide hydrolase 2)
Protein function Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corres
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01425 Amidase 69 → 513 Amidase Family
Tissue specificity TISSUE SPECIFICITY: Expressed in kidney, liver, lung, prostate, heart and ovary. {ECO:0000269|PubMed:17015445, ECO:0000305|PubMed:19926788}.
Sequence
Sequence length 532
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Arachidonic acid metabolism
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Papillary renal carcinoma Papillary Renal Cell Carcinoma rs5030823, rs2137087134, rs121913668, rs121913669, rs121913670, rs121913671, rs121913673, rs121913243, rs786202724 25401301
Renal carcinoma Renal Cell Carcinoma, Conventional (Clear Cell) Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Collecting Duct Carcinoma of the Kidney rs121913668, rs121913670, rs121913243, rs786202724 25401301
Show/Hide Unknown Diseases (4)
Unknown
Disease term Disease name Evidence References Source
Chromophobe carcinoma Chromophobe Renal Cell Carcinoma 25401301 ClinVar
Neuroticism Neuroticism GWAS
Diabetes Diabetes GWAS
Hypogonadism Hypogonadism GWAS
Show/Hide Text Mining Associations (7)
Associations from Text Mining
Disease Name Relationship Type References
Ataxia Associate 25885783
Autistic Disorder Associate 25885783
Genetic Diseases Inborn Associate 25885783
Idiopathic Hypogonadotropic Hypogonadism Associate 26239645
Intellectual Disability Associate 20655035
Lysosomal acid lipase deficiency Associate 25885783
Mental Disorders Associate 25885783