Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
154091
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 2 member 12
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC2A12
Synonyms (NCBI Gene) Gene synonyms aliases
GLUT12, GLUT8
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q23.2
Summary Summary of gene provided in NCBI Entrez Gene.
SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid re
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017063 hsa-miR-335-5p Microarray 18185580
MIRT518659 hsa-miR-5011-5p HITS-CLIP 21572407
MIRT518658 hsa-miR-501-3p HITS-CLIP 21572407
MIRT518657 hsa-miR-502-3p HITS-CLIP 21572407
MIRT518656 hsa-miR-767-5p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane TAS
GO:0008645 Process Hexose transmembrane transport TAS
GO:0012505 Component Endomembrane system IEA
GO:0016021 Component Integral component of membrane IEA
GO:0022857 Function Transmembrane transporter activity IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610372 18067 ENSG00000146411
Protein
UniProt ID Q8TD20
Protein name Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)
Protein function Insulin-independent facilitative glucose transporter.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00083 Sugar_tr 43 375 Sugar (and other) transporter Family
PF00083 Sugar_tr 441 564 Sugar (and other) transporter Family
Tissue specificity TISSUE SPECIFICITY: Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney. {ECO:0000269|PubMed:11832379}.
Sequence
Sequence length 617
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Cellular hexose transport
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 29212778
Unknown
Disease term Disease name Evidence References Source
Oligodendroglioma Oligodendroglioma GWAS
Prostate cancer Prostate cancer Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Diabetes Gestational Associate 34555239
Hyperglycemic Hyperosmolar Nonketotic Coma Associate 25776730
Neoplasms Associate 12673735, 21862591, 36594084
Neural Tube Defects Associate 25776730
Prostatic Neoplasms Associate 29431615
Prostatitis Associate 12673735
Squamous Cell Carcinoma of Head and Neck Associate 37542344
Stomach Neoplasms Associate 32799763
Stomach Neoplasms Stimulate 36594084