RAET1L (retinoic acid early transcript 1L)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID 154064
Gene name Retinoic acid early transcript 1L
Gene symbol RAET1L
Synonyms (NCBI Gene)
RAET1HULBP6
Chromosome 6
Chromosome location 6q25.1
Summary RAET1L belongs to the RAET1 family of major histocompatibility complex (MHC) class I-related genes, which are located within a 180-kb cluster on chromosome 6q24.2-q25.3. The REAT1 genes encode glycoproteins that contain extracellular alpha-1 and alpha-2 d
miRNA miRNA information provided by mirtarbase database.
112
Gene miRNA Gene ontology Other IDs Protein Pathways
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miRTarBase ID miRNA Experiments Reference
MIRT492514 hsa-miR-29a-3p PAR-CLIP 23592263
MIRT492513 hsa-miR-29b-3p PAR-CLIP 23592263
MIRT492512 hsa-miR-29c-3p PAR-CLIP 23592263
MIRT492511 hsa-miR-6871-3p PAR-CLIP 23592263
MIRT492509 hsa-miR-6884-3p PAR-CLIP 23592263
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
Gene miRNA Gene ontology Other IDs Protein Pathways
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GO ID Ontology Definition Evidence Reference
GO:0001916 Process Positive regulation of T cell mediated cytotoxicity IBA
GO:0002376 Process Immune system process IEA
GO:0002476 Process Antigen processing and presentation of endogenous peptide antigen via MHC class Ib IBA
GO:0002486 Process Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IBA
GO:0005515 Function Protein binding IPI 19658097, 28559451, 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
611047 16798 ENSG00000155918
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5VY80
Protein name UL16-binding protein 6 (Retinoic acid early transcript 1L protein)
Protein function Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
PDB 4S0U , 8RWB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00129 MHC_I 29 → 205 Class I Histocompatibility antigen, domains alpha 1 and 2 Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed (PubMed:11827464). Expressed in trachea (PubMed:19658097). Constitutively expressed in peripheral blood mononuclear cells, including B-cells and natural killer cells, as well as CD4+ and CD8+ T-cells and monocytes. Ten
Sequence
Sequence length 246
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  KEGG  Reactome
  Natural killer cell mediated cytotoxicity   Post-translational modification: synthesis of GPI-anchored proteins