Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	152404
Gene name	Immunoglobulin superfamily member 11
Gene symbol	IGSF11
Synonyms (NCBI Gene)	BT-IgSFBTIGSFCT119CXADRL1Igsf13VSIG3
Chromosome	3
Chromosome location	3q13.32
Summary	IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM

Show/Hide all (79)

miRTarBase ID	miRNA	Experiments	Reference
MIRT617993	hsa-miR-3163	HITS-CLIP	19536157
MIRT617992	hsa-miR-340-5p	HITS-CLIP	19536157
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	19536157
MIRT617993	hsa-miR-3163	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617993	hsa-miR-3163	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617993	hsa-miR-3163	HITS-CLIP	19536157
MIRT617992	hsa-miR-340-5p	HITS-CLIP	19536157
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	19536157
MIRT617993	hsa-miR-3163	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT617993	hsa-miR-3163	HITS-CLIP	23824327
MIRT617992	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT617991	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT617990	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT755582	hsa-miR-125a-5p	Western blottingqRT-PCRImmunoprecipitaion (IP)CLIP-seqChIP-seqFlow cytometryRNA pull down assay	37370798
MIRT755582	hsa-miR-125a-5p	CLIP-seq
MIRT1062472	hsa-miR-125b	CLIP-seq
MIRT1062473	hsa-miR-1913	CLIP-seq
MIRT1062474	hsa-miR-2110	CLIP-seq
MIRT1062475	hsa-miR-324-3p	CLIP-seq
MIRT1062476	hsa-miR-346	CLIP-seq
MIRT1062477	hsa-miR-4271	CLIP-seq
MIRT1062478	hsa-miR-4290	CLIP-seq
MIRT1062479	hsa-miR-4319	CLIP-seq
MIRT1062480	hsa-miR-4725-3p	CLIP-seq
MIRT1062481	hsa-miR-4732-3p	CLIP-seq
MIRT1062482	hsa-miR-491-5p	CLIP-seq
MIRT1062483	hsa-miR-541	CLIP-seq
MIRT1062484	hsa-miR-654-5p	CLIP-seq
MIRT1062485	hsa-miR-670	CLIP-seq
MIRT1062486	hsa-miR-9	CLIP-seq
MIRT1062487	hsa-miR-103a	CLIP-seq
MIRT1062488	hsa-miR-106a	CLIP-seq
MIRT1062489	hsa-miR-106b	CLIP-seq
MIRT1062490	hsa-miR-107	CLIP-seq
MIRT1062491	hsa-miR-1301	CLIP-seq
MIRT1062492	hsa-miR-142-5p	CLIP-seq
MIRT1062493	hsa-miR-17	CLIP-seq
MIRT1062494	hsa-miR-20a	CLIP-seq
MIRT1062495	hsa-miR-20b	CLIP-seq
MIRT1062496	hsa-miR-3609	CLIP-seq
MIRT1062497	hsa-miR-376c	CLIP-seq
MIRT1062498	hsa-miR-423-3p	CLIP-seq
MIRT1062499	hsa-miR-4714-3p	CLIP-seq
MIRT1062500	hsa-miR-4796-3p	CLIP-seq
MIRT1062501	hsa-miR-5047	CLIP-seq
MIRT1062502	hsa-miR-519d	CLIP-seq
MIRT1062503	hsa-miR-548ah	CLIP-seq
MIRT1062504	hsa-miR-646	CLIP-seq
MIRT1062505	hsa-miR-93	CLIP-seq
MIRT2014761	hsa-miR-4495	CLIP-seq
MIRT2247047	hsa-miR-1298	CLIP-seq
MIRT2247048	hsa-miR-23a	CLIP-seq
MIRT2247049	hsa-miR-23b	CLIP-seq
MIRT2247050	hsa-miR-23c	CLIP-seq
MIRT2247051	hsa-miR-548u	CLIP-seq
MIRT2247052	hsa-miR-664	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	26595655, 32296183
GO:0005886	Component	Plasma membrane	IEA
GO:0005911	Component	Cell-cell junction	IBA
GO:0005911	Component	Cell-cell junction	IDA	26595655
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IMP	15795899
GO:0016020	Component	Membrane	IEA
GO:0035255	Function	Ionotropic glutamate receptor binding	IPI	26595655
GO:0045202	Component	Synapse	IEA
GO:0048167	Process	Regulation of synaptic plasticity	IEA
GO:0098742	Process	Cell-cell adhesion via plasma-membrane adhesion molecules	IBA
GO:0099537	Process	Trans-synaptic signaling	IEA
GO:1900273	Process	Positive regulation of long-term synaptic potentiation	IEA
GO:1905606	Process	Regulation of presynapse assembly	IEA

MIM	HGNC	e!Ensembl
608351	16669	ENSG00000144847

Q5DX21

Protein name

Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (V-set and immunoglobulin domain-containing protein 3)

Protein function

Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07686	V-set	27 → 141	Immunoglobulin V-set domain	Domain
PF13927	Ig_3	145 → 219		Domain

Tissue specificity

TISSUE SPECIFICITY: Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle. {ECO:0000269|PubMed:16108831}.

Sequence

MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWM
VTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQC
LVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEK
LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNI
GLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFH
TEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYAN
GTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVM
VPAQSRAGSLV

Sequence length

431

Interactions

View interactions

	KEGG
	Cell adhesion molecules

IGSF11 (immunoglobulin superfamily member 11)