ZNF385B (zinc finger protein 385B)

Gene

• Entrez ID: 151126
• Gene name: Zinc finger protein 385B
• Gene symbol: ZNF385B
• Synonyms (NCBI Gene): ZNF533
• Chromosome: 2
• Chromosome location: 2q31.2-q31.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024722	hsa-miR-215-5p	Microarray	19074876
MIRT026853	hsa-miR-192-5p	Microarray	19074876
MIRT1523592	hsa-miR-1278	CLIP-seq
MIRT1523593	hsa-miR-3120-3p	CLIP-seq
MIRT1523594	hsa-miR-325	CLIP-seq
MIRT1523595	hsa-miR-4672	CLIP-seq
MIRT1523596	hsa-miR-628-3p	CLIP-seq
MIRT1523597	hsa-miR-1283	CLIP-seq
MIRT1523598	hsa-miR-3678-3p	CLIP-seq
MIRT1523599	hsa-miR-3915	CLIP-seq
MIRT1523600	hsa-miR-3928	CLIP-seq
MIRT1523601	hsa-miR-5095	CLIP-seq
MIRT1523602	hsa-miR-552	CLIP-seq
MIRT2397532	hsa-miR-1275	CLIP-seq
MIRT2397533	hsa-miR-4525	CLIP-seq
MIRT2397534	hsa-miR-4665-5p	CLIP-seq
MIRT2397535	hsa-miR-4723-5p	CLIP-seq
MIRT2397536	hsa-miR-625	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002039	Function	P53 binding	IPI	22945289
GO:0003676	Function	Nucleic acid binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	22945289
GO:0005634	Component	Nucleus	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0072332	Process	Intrinsic apoptotic signaling pathway by p53 class mediator	IDA	22945289

Other IDs

• MIM: 612344
• HGNC: 26332
• e!Ensembl: ENSG00000144331

Protein

• UniProt ID: Q569K4
• Protein name: Zinc finger protein 385B (Zinc finger protein 533)
• Protein function: May play a role in p53/TP53-mediated apoptosis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12874	zf-met	34 → 58		Domain
  PF12874	zf-met	157 → 181		Domain
  PF12874	zf-met	285 → 309		Domain
  PF12874	zf-met	348 → 372		Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in germinal center of lymph node (at protein level). Expressed in spleen, lymph node and tonsil. {ECO:0000269|PubMed:22945289}.
• Sequence:

  MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRK
  RVKQLSDGQPPPPAQASPSSNSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDS
  SSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSK
  HAKKVKALDATKNKPKMVPSKDSAKANPSCSITPITGNNSDKSEDKGKLKASSSSQPSSS
  ESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKAKKLLYCSLCKVAVNSLSQL
  EAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSE
  IQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSP
  LAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY

• Sequence length: 471