Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
146664
Gene name Gene Name - the full gene name approved by the HGNC.
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MGAT5B
Synonyms (NCBI Gene) Gene synonyms aliases
GnT-IX, GnT-VB
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q25.2
Summary Summary of gene provided in NCBI Entrez Gene.
The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT716472 hsa-miR-6849-3p HITS-CLIP 19536157
MIRT709057 hsa-miR-6887-3p HITS-CLIP 19536157
MIRT709054 hsa-miR-4749-3p HITS-CLIP 19536157
MIRT709053 hsa-miR-874-5p HITS-CLIP 19536157
MIRT716471 hsa-miR-6512-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005515 Function Protein binding IPI 23088713
GO:0005794 Component Golgi apparatus IBA 21873635
GO:0006487 Process Protein N-linked glycosylation IBA 21873635
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612441 24140 ENSG00000167889
Protein
UniProt ID Q3V5L5
Protein name Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.-) (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B) (GlcNAc-T Vb) (GNT-Vb) (hGnTVb) (Mannoside acetylglucosaminyltransferase 5B) (N-acetylglucosam
Protein function Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- an
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15024 Glyco_transf_18 184 777 Glycosyltransferase family 18 Family
Tissue specificity TISSUE SPECIFICITY: Predominantly expressed in brain. Expressed in all areas of the adult and fetal brain. Also expressed at much lower levels in testis, spleen and thymus. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14623122}.
Sequence
Sequence length 792
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  N-Glycan biosynthesis
Mannose type O-glycan biosynthesis
Metabolic pathways
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Pulmonary Emphysema Pulmonary Emphysema GWAS
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Transitional Cell Associate 31805718
Colorectal Neoplasms Associate 10673297
Genetic Diseases Inborn Associate 18838383
Glioma Associate 17255279
Neoplasms Associate 23107376
Peritoneal Fibrosis Associate 37335673
Prostatic Neoplasms Associate 35246070
Stomach Neoplasms Associate 23107376
Thecoma Associate 37335673
Uveal melanoma Associate 18385798