Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	144165
Gene name Gene Name - the full gene name approved by the HGNC.	Prickle planar cell polarity protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PRICKLE1
Synonyms (NCBI Gene) Gene synonyms aliases	EPM1B, RILP
Disease Acronyms (UniProt) Disease acronyms from UniProt database	EPM1B
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q12
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/

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SNP ID	Visualize variation	Clinical significance	Consequence
rs79087668	C>T	Benign, benign-likely-benign, pathogenic	Coding sequence variant, missense variant
rs113994140	C>T	Pathogenic, likely-pathogenic	Coding sequence variant, missense variant
rs116197349	G>A,C	Conflicting-interpretations-of-pathogenicity, benign, uncertain-significance	Coding sequence variant, synonymous variant, missense variant
rs138452760	G>A	Pathogenic, uncertain-significance	Coding sequence variant, missense variant
rs141743294	C>T	Conflicting-interpretations-of-pathogenicity, benign, likely-benign	Synonymous variant, coding sequence variant
rs145493619	G>A,C	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs146650383	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Synonymous variant, coding sequence variant
rs149496604	T>C	Benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs150545495	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, coding sequence variant
rs281865563	C>T	Uncertain-significance, pathogenic	Missense variant, coding sequence variant
rs281865564	A>G	Pathogenic	Missense variant, coding sequence variant
rs781255236	C>A,T	Pathogenic, uncertain-significance	Missense variant, coding sequence variant

Show/Hide all(508)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024610	hsa-miR-215-5p	Microarray	19074876
MIRT026529	hsa-miR-192-5p	Microarray	19074876
MIRT050925	hsa-miR-17-5p	CLASH	23622248
MIRT680736	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT680735	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT680734	hsa-miR-4257	HITS-CLIP	23706177
MIRT680733	hsa-miR-1247-3p	HITS-CLIP	23706177
MIRT680732	hsa-miR-5186	HITS-CLIP	23706177
MIRT680731	hsa-miR-1827	HITS-CLIP	23706177
MIRT680730	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT680729	hsa-miR-6086	HITS-CLIP	23706177
MIRT680728	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT680727	hsa-miR-6499-3p	HITS-CLIP	23706177
MIRT680726	hsa-miR-3612	HITS-CLIP	23706177
MIRT680725	hsa-miR-650	HITS-CLIP	23706177
MIRT680724	hsa-miR-203b-3p	HITS-CLIP	23706177
MIRT272927	hsa-miR-455-3p	HITS-CLIP	23706177
MIRT680723	hsa-miR-6516-5p	HITS-CLIP	23706177
MIRT654806	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT654805	hsa-miR-551b-5p	HITS-CLIP	23824327
MIRT654804	hsa-miR-4704-3p	HITS-CLIP	23824327
MIRT654803	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT654802	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT654801	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT630302	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT630301	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT630300	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT654800	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT630299	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630298	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630297	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630296	hsa-miR-4284	HITS-CLIP	23824327
MIRT630295	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT654799	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT654798	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT654797	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT654796	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT654795	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT654794	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT654793	hsa-miR-4325	HITS-CLIP	23824327
MIRT630294	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT654792	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT654791	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT654790	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT654789	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT654788	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT654787	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT654786	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT654785	hsa-miR-3689c	HITS-CLIP	23824327
MIRT654784	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT654783	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT654782	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT654781	hsa-miR-3122	HITS-CLIP	23824327
MIRT654780	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT654779	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT654778	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT654777	hsa-miR-665	HITS-CLIP	23824327
MIRT630303	hsa-miR-5693	HITS-CLIP	23824327
MIRT630302	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT630301	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT630300	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT630299	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630298	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630297	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630296	hsa-miR-4284	HITS-CLIP	23824327
MIRT630295	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630294	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT272942	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT566292	hsa-miR-6771-3p	PAR-CLIP	20371350
MIRT566291	hsa-miR-6732-3p	PAR-CLIP	20371350
MIRT566290	hsa-miR-4732-3p	PAR-CLIP	20371350
MIRT566289	hsa-miR-6831-3p	PAR-CLIP	20371350
MIRT485233	hsa-miR-488-5p	PAR-CLIP	23592263
MIRT485232	hsa-miR-6780b-3p	PAR-CLIP	23592263
MIRT485231	hsa-miR-581	PAR-CLIP	23592263
MIRT485230	hsa-miR-92b-5p	PAR-CLIP	23592263
MIRT485229	hsa-miR-4648	PAR-CLIP	23592263
MIRT485228	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT485227	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT485226	hsa-miR-4654	PAR-CLIP	23592263
MIRT485225	hsa-miR-4769-5p	PAR-CLIP	23592263
MIRT485224	hsa-miR-3911	PAR-CLIP	23592263
MIRT485223	hsa-miR-644a	PAR-CLIP	23592263
MIRT485221	hsa-miR-6818-5p	PAR-CLIP	23592263
MIRT485222	hsa-miR-147a	PAR-CLIP	23592263
MIRT485220	hsa-miR-2355-5p	PAR-CLIP	23592263
MIRT680736	hsa-miR-1910-3p	HITS-CLIP	23706177
MIRT680735	hsa-miR-6511a-5p	HITS-CLIP	23706177
MIRT680734	hsa-miR-4257	HITS-CLIP	23706177
MIRT680733	hsa-miR-1247-3p	HITS-CLIP	23706177
MIRT680732	hsa-miR-5186	HITS-CLIP	23706177
MIRT680731	hsa-miR-1827	HITS-CLIP	23706177
MIRT680730	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT680729	hsa-miR-6086	HITS-CLIP	23706177
MIRT680728	hsa-miR-2467-3p	HITS-CLIP	23706177
MIRT680727	hsa-miR-6499-3p	HITS-CLIP	23706177
MIRT680726	hsa-miR-3612	HITS-CLIP	23706177
MIRT680725	hsa-miR-650	HITS-CLIP	23706177
MIRT680724	hsa-miR-203b-3p	HITS-CLIP	23706177
MIRT272927	hsa-miR-455-3p	HITS-CLIP	23706177
MIRT680723	hsa-miR-6516-5p	HITS-CLIP	23706177
MIRT654806	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT654805	hsa-miR-551b-5p	HITS-CLIP	23824327
MIRT654804	hsa-miR-4704-3p	HITS-CLIP	23824327
MIRT654803	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT654802	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT654801	hsa-miR-4799-5p	HITS-CLIP	23824327
MIRT630302	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT630301	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT630300	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT654800	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT630299	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630298	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630297	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630296	hsa-miR-4284	HITS-CLIP	23824327
MIRT630295	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT654799	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT654798	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT654797	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT654796	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT654795	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT654794	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT654793	hsa-miR-4325	HITS-CLIP	23824327
MIRT630294	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT654792	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT654791	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT654790	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT654789	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT654788	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT654787	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT654786	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT654785	hsa-miR-3689c	HITS-CLIP	23824327
MIRT654784	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT654783	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT654782	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT654781	hsa-miR-3122	HITS-CLIP	23824327
MIRT654780	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT654779	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT654778	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT654777	hsa-miR-665	HITS-CLIP	23824327
MIRT630303	hsa-miR-5693	HITS-CLIP	23824327
MIRT630302	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT630301	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT630300	hsa-miR-331-3p	HITS-CLIP	23824327
MIRT630299	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630298	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630297	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630296	hsa-miR-4284	HITS-CLIP	23824327
MIRT630295	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630294	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT272942	hsa-miR-340-5p	PAR-CLIP	20371350
MIRT566292	hsa-miR-6771-3p	PAR-CLIP	20371350
MIRT566291	hsa-miR-6732-3p	PAR-CLIP	20371350
MIRT566290	hsa-miR-4732-3p	PAR-CLIP	20371350
MIRT566289	hsa-miR-6831-3p	PAR-CLIP	20371350
MIRT485233	hsa-miR-488-5p	PAR-CLIP	23592263
MIRT485232	hsa-miR-6780b-3p	PAR-CLIP	23592263
MIRT485231	hsa-miR-581	PAR-CLIP	23592263
MIRT485230	hsa-miR-92b-5p	PAR-CLIP	23592263
MIRT485229	hsa-miR-4648	PAR-CLIP	23592263
MIRT485228	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT485227	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT485226	hsa-miR-4654	PAR-CLIP	23592263
MIRT485225	hsa-miR-4769-5p	PAR-CLIP	23592263
MIRT485224	hsa-miR-3911	PAR-CLIP	23592263
MIRT485223	hsa-miR-644a	PAR-CLIP	23592263
MIRT485221	hsa-miR-6818-5p	PAR-CLIP	23592263
MIRT485222	hsa-miR-147a	PAR-CLIP	23592263
MIRT485220	hsa-miR-2355-5p	PAR-CLIP	23592263
MIRT1261369	hsa-miR-1207-5p	CLIP-seq
MIRT1261370	hsa-miR-1224-5p	CLIP-seq
MIRT1261371	hsa-miR-1909	CLIP-seq
MIRT1261372	hsa-miR-204	CLIP-seq
MIRT1261373	hsa-miR-211	CLIP-seq
MIRT1261374	hsa-miR-3148	CLIP-seq
MIRT1261375	hsa-miR-3169	CLIP-seq
MIRT1261376	hsa-miR-3915	CLIP-seq
MIRT1261377	hsa-miR-3938	CLIP-seq
MIRT1261378	hsa-miR-4514	CLIP-seq
MIRT1261379	hsa-miR-4515	CLIP-seq
MIRT1261380	hsa-miR-4668-5p	CLIP-seq
MIRT1261381	hsa-miR-4689	CLIP-seq
MIRT1261382	hsa-miR-4692	CLIP-seq
MIRT1261383	hsa-miR-4716-3p	CLIP-seq
MIRT1261384	hsa-miR-4751	CLIP-seq
MIRT1261385	hsa-miR-4755-5p	CLIP-seq
MIRT1261386	hsa-miR-4763-3p	CLIP-seq
MIRT1261387	hsa-miR-4780	CLIP-seq
MIRT1261388	hsa-miR-548aa	CLIP-seq
MIRT1261389	hsa-miR-548ac	CLIP-seq
MIRT1261390	hsa-miR-548d-3p	CLIP-seq
MIRT1261391	hsa-miR-548z	CLIP-seq
MIRT1261392	hsa-miR-623	CLIP-seq
MIRT1261393	hsa-miR-625	CLIP-seq
MIRT1261394	hsa-miR-875-3p	CLIP-seq
MIRT1261395	hsa-miR-940	CLIP-seq
MIRT1261396	hsa-miR-101	CLIP-seq
MIRT1261397	hsa-miR-144	CLIP-seq
MIRT1261398	hsa-miR-323-3p	CLIP-seq
MIRT1261399	hsa-miR-3545-3p	CLIP-seq
MIRT1261400	hsa-miR-3652	CLIP-seq
MIRT1261401	hsa-miR-4430	CLIP-seq
MIRT1261402	hsa-miR-4473	CLIP-seq
MIRT1261403	hsa-miR-4505	CLIP-seq
MIRT1261404	hsa-miR-4539	CLIP-seq
MIRT1261405	hsa-miR-4704-5p	CLIP-seq
MIRT1261406	hsa-miR-4803	CLIP-seq
MIRT1261407	hsa-miR-512-3p	CLIP-seq
MIRT1261408	hsa-miR-520d-5p	CLIP-seq
MIRT1261409	hsa-miR-520f	CLIP-seq
MIRT1261410	hsa-miR-524-5p	CLIP-seq
MIRT1261411	hsa-miR-767-5p	CLIP-seq
MIRT1552560	hsa-miR-4310	CLIP-seq
MIRT2076900	hsa-miR-4477a	CLIP-seq
MIRT2076901	hsa-miR-595	CLIP-seq
MIRT2303551	hsa-miR-4328	CLIP-seq
MIRT1261396	hsa-miR-101	CLIP-seq
MIRT1261397	hsa-miR-144	CLIP-seq
MIRT2432258	hsa-miR-147	CLIP-seq
MIRT1261398	hsa-miR-323-3p	CLIP-seq
MIRT1261399	hsa-miR-3545-3p	CLIP-seq
MIRT1261404	hsa-miR-4539	CLIP-seq
MIRT2432259	hsa-miR-4685-5p	CLIP-seq
MIRT2432260	hsa-miR-4729	CLIP-seq
MIRT2432261	hsa-miR-4789-5p	CLIP-seq
MIRT2432262	hsa-miR-507	CLIP-seq
MIRT2432263	hsa-miR-557	CLIP-seq
MIRT2432264	hsa-miR-582-5p	CLIP-seq
MIRT2432265	hsa-miR-644	CLIP-seq
MIRT2432266	hsa-miR-889	CLIP-seq
MIRT1261396	hsa-miR-101	CLIP-seq
MIRT2600143	hsa-miR-103b	CLIP-seq
MIRT2600144	hsa-miR-105	CLIP-seq
MIRT1261370	hsa-miR-1224-5p	CLIP-seq
MIRT2600145	hsa-miR-1228	CLIP-seq
MIRT2600146	hsa-miR-124	CLIP-seq
MIRT2600147	hsa-miR-1270	CLIP-seq
MIRT2600148	hsa-miR-1273e	CLIP-seq
MIRT2600149	hsa-miR-1279	CLIP-seq
MIRT2600150	hsa-miR-128	CLIP-seq
MIRT2600151	hsa-miR-1305	CLIP-seq
MIRT2600152	hsa-miR-136	CLIP-seq
MIRT1261397	hsa-miR-144	CLIP-seq
MIRT2432258	hsa-miR-147	CLIP-seq
MIRT2600153	hsa-miR-183	CLIP-seq
MIRT1261372	hsa-miR-204	CLIP-seq
MIRT2600154	hsa-miR-2053	CLIP-seq
MIRT1261373	hsa-miR-211	CLIP-seq
MIRT2600155	hsa-miR-302f	CLIP-seq
MIRT2600156	hsa-miR-3064-3p	CLIP-seq
MIRT2600157	hsa-miR-3065-5p	CLIP-seq
MIRT2600158	hsa-miR-30a	CLIP-seq
MIRT2600159	hsa-miR-30b	CLIP-seq
MIRT2600160	hsa-miR-30c	CLIP-seq
MIRT2600161	hsa-miR-30d	CLIP-seq
MIRT2600162	hsa-miR-30e	CLIP-seq
MIRT2600163	hsa-miR-3117-5p	CLIP-seq
MIRT2600164	hsa-miR-3124-3p	CLIP-seq
MIRT2600165	hsa-miR-3130-5p	CLIP-seq
MIRT2600166	hsa-miR-3135b	CLIP-seq
MIRT1261374	hsa-miR-3148	CLIP-seq
MIRT2600167	hsa-miR-3152-3p	CLIP-seq
MIRT1261375	hsa-miR-3169	CLIP-seq
MIRT2600168	hsa-miR-3176	CLIP-seq
MIRT2600169	hsa-miR-3200-3p	CLIP-seq
MIRT2600170	hsa-miR-320e	CLIP-seq
MIRT2600171	hsa-miR-330-3p	CLIP-seq
MIRT2600172	hsa-miR-338-5p	CLIP-seq
MIRT2600173	hsa-miR-34c-3p	CLIP-seq
MIRT2600174	hsa-miR-3607-3p	CLIP-seq
MIRT2600175	hsa-miR-3613-3p	CLIP-seq
MIRT2600176	hsa-miR-3622a-5p	CLIP-seq
MIRT2600177	hsa-miR-3647-3p	CLIP-seq
MIRT2600178	hsa-miR-3651	CLIP-seq
MIRT1261400	hsa-miR-3652	CLIP-seq
MIRT2600179	hsa-miR-3662	CLIP-seq
MIRT2600180	hsa-miR-3667-5p	CLIP-seq
MIRT2600181	hsa-miR-3671	CLIP-seq
MIRT2600182	hsa-miR-3685	CLIP-seq
MIRT2600183	hsa-miR-376c	CLIP-seq
MIRT2600184	hsa-miR-384	CLIP-seq
MIRT1261376	hsa-miR-3915	CLIP-seq
MIRT2600185	hsa-miR-3922-3p	CLIP-seq
MIRT2600186	hsa-miR-3926	CLIP-seq
MIRT1261377	hsa-miR-3938	CLIP-seq
MIRT2600187	hsa-miR-3942-3p	CLIP-seq
MIRT2600188	hsa-miR-3943	CLIP-seq
MIRT2600189	hsa-miR-3978	CLIP-seq
MIRT1552560	hsa-miR-4310	CLIP-seq
MIRT2600190	hsa-miR-4323	CLIP-seq
MIRT2303551	hsa-miR-4328	CLIP-seq
MIRT2600191	hsa-miR-4426	CLIP-seq
MIRT1261401	hsa-miR-4430	CLIP-seq
MIRT2600192	hsa-miR-4434	CLIP-seq
MIRT2600193	hsa-miR-4452	CLIP-seq
MIRT1261402	hsa-miR-4473	CLIP-seq
MIRT2600194	hsa-miR-4482	CLIP-seq
MIRT2600195	hsa-miR-4484	CLIP-seq
MIRT2600196	hsa-miR-4496	CLIP-seq
MIRT1261403	hsa-miR-4505	CLIP-seq
MIRT1261379	hsa-miR-4515	CLIP-seq
MIRT2600197	hsa-miR-4516	CLIP-seq
MIRT2600198	hsa-miR-4531	CLIP-seq
MIRT2600199	hsa-miR-4537	CLIP-seq
MIRT2600200	hsa-miR-4647	CLIP-seq
MIRT2600201	hsa-miR-4653-3p	CLIP-seq
MIRT2600202	hsa-miR-4662b	CLIP-seq
MIRT2600203	hsa-miR-4666-3p	CLIP-seq
MIRT2600204	hsa-miR-4666-5p	CLIP-seq
MIRT2432259	hsa-miR-4685-5p	CLIP-seq
MIRT2600205	hsa-miR-4686	CLIP-seq
MIRT1261381	hsa-miR-4689	CLIP-seq
MIRT2600206	hsa-miR-4698	CLIP-seq
MIRT1261405	hsa-miR-4704-5p	CLIP-seq
MIRT2432260	hsa-miR-4729	CLIP-seq
MIRT2600207	hsa-miR-4735-5p	CLIP-seq
MIRT1261384	hsa-miR-4751	CLIP-seq
MIRT2600208	hsa-miR-4753-5p	CLIP-seq
MIRT1261385	hsa-miR-4755-5p	CLIP-seq
MIRT2600209	hsa-miR-4757-5p	CLIP-seq
MIRT2600210	hsa-miR-4758-3p	CLIP-seq
MIRT1261387	hsa-miR-4780	CLIP-seq
MIRT2432261	hsa-miR-4789-5p	CLIP-seq
MIRT2600211	hsa-miR-4797-5p	CLIP-seq
MIRT2600212	hsa-miR-4802-3p	CLIP-seq
MIRT1261406	hsa-miR-4803	CLIP-seq
MIRT2600213	hsa-miR-494	CLIP-seq
MIRT2600214	hsa-miR-502-5p	CLIP-seq
MIRT2600215	hsa-miR-506	CLIP-seq
MIRT2600216	hsa-miR-5096	CLIP-seq
MIRT1261407	hsa-miR-512-3p	CLIP-seq
MIRT2600217	hsa-miR-513b	CLIP-seq
MIRT2600218	hsa-miR-515-5p	CLIP-seq
MIRT1261408	hsa-miR-520d-5p	CLIP-seq
MIRT1261409	hsa-miR-520f	CLIP-seq
MIRT1261410	hsa-miR-524-5p	CLIP-seq
MIRT2600219	hsa-miR-539	CLIP-seq
MIRT1261388	hsa-miR-548aa	CLIP-seq
MIRT2600220	hsa-miR-548an	CLIP-seq
MIRT2600221	hsa-miR-548c-3p	CLIP-seq
MIRT2600222	hsa-miR-548s	CLIP-seq
MIRT2600223	hsa-miR-569	CLIP-seq
MIRT2432264	hsa-miR-582-5p	CLIP-seq
MIRT2600224	hsa-miR-583	CLIP-seq
MIRT2600225	hsa-miR-587	CLIP-seq
MIRT2600226	hsa-miR-600	CLIP-seq
MIRT2600227	hsa-miR-607	CLIP-seq
MIRT2600228	hsa-miR-616	CLIP-seq
MIRT2600229	hsa-miR-619	CLIP-seq
MIRT2600230	hsa-miR-620	CLIP-seq
MIRT1261392	hsa-miR-623	CLIP-seq
MIRT2600231	hsa-miR-628-5p	CLIP-seq
MIRT2432265	hsa-miR-644	CLIP-seq
MIRT2600232	hsa-miR-646	CLIP-seq
MIRT2600233	hsa-miR-659	CLIP-seq
MIRT2600234	hsa-miR-767-3p	CLIP-seq
MIRT1261411	hsa-miR-767-5p	CLIP-seq
MIRT2600235	hsa-miR-802	CLIP-seq
MIRT1261394	hsa-miR-875-3p	CLIP-seq
MIRT2600236	hsa-miR-888	CLIP-seq
MIRT2432266	hsa-miR-889	CLIP-seq
MIRT1261396	hsa-miR-101	CLIP-seq
MIRT2600143	hsa-miR-103b	CLIP-seq
MIRT2600144	hsa-miR-105	CLIP-seq
MIRT1261369	hsa-miR-1207-5p	CLIP-seq
MIRT1261370	hsa-miR-1224-5p	CLIP-seq
MIRT2600145	hsa-miR-1228	CLIP-seq
MIRT2600146	hsa-miR-124	CLIP-seq
MIRT2688564	hsa-miR-1252	CLIP-seq
MIRT2600147	hsa-miR-1270	CLIP-seq
MIRT2600148	hsa-miR-1273e	CLIP-seq
MIRT2600149	hsa-miR-1279	CLIP-seq
MIRT2600150	hsa-miR-128	CLIP-seq
MIRT2688565	hsa-miR-1296	CLIP-seq
MIRT2600151	hsa-miR-1305	CLIP-seq
MIRT2600152	hsa-miR-136	CLIP-seq
MIRT2688566	hsa-miR-141	CLIP-seq
MIRT1261397	hsa-miR-144	CLIP-seq
MIRT2432258	hsa-miR-147	CLIP-seq
MIRT2600153	hsa-miR-183	CLIP-seq
MIRT1261371	hsa-miR-1909	CLIP-seq
MIRT2688567	hsa-miR-200a	CLIP-seq
MIRT1261372	hsa-miR-204	CLIP-seq
MIRT2600154	hsa-miR-2053	CLIP-seq
MIRT1261373	hsa-miR-211	CLIP-seq
MIRT2600155	hsa-miR-302f	CLIP-seq
MIRT2600156	hsa-miR-3064-3p	CLIP-seq
MIRT2600157	hsa-miR-3065-5p	CLIP-seq
MIRT2600158	hsa-miR-30a	CLIP-seq
MIRT2600159	hsa-miR-30b	CLIP-seq
MIRT2600160	hsa-miR-30c	CLIP-seq
MIRT2600161	hsa-miR-30d	CLIP-seq
MIRT2600162	hsa-miR-30e	CLIP-seq
MIRT2600163	hsa-miR-3117-5p	CLIP-seq
MIRT2600164	hsa-miR-3124-3p	CLIP-seq
MIRT2600165	hsa-miR-3130-5p	CLIP-seq
MIRT2600166	hsa-miR-3135b	CLIP-seq
MIRT1261374	hsa-miR-3148	CLIP-seq
MIRT2600167	hsa-miR-3152-3p	CLIP-seq
MIRT1261375	hsa-miR-3169	CLIP-seq
MIRT2600168	hsa-miR-3176	CLIP-seq
MIRT2600169	hsa-miR-3200-3p	CLIP-seq
MIRT2600170	hsa-miR-320e	CLIP-seq
MIRT2600171	hsa-miR-330-3p	CLIP-seq
MIRT2600172	hsa-miR-338-5p	CLIP-seq
MIRT2600174	hsa-miR-3607-3p	CLIP-seq
MIRT2600175	hsa-miR-3613-3p	CLIP-seq
MIRT2600176	hsa-miR-3622a-5p	CLIP-seq
MIRT2600177	hsa-miR-3647-3p	CLIP-seq
MIRT2600178	hsa-miR-3651	CLIP-seq
MIRT1261400	hsa-miR-3652	CLIP-seq
MIRT2600179	hsa-miR-3662	CLIP-seq
MIRT2600180	hsa-miR-3667-5p	CLIP-seq
MIRT2600181	hsa-miR-3671	CLIP-seq
MIRT2600182	hsa-miR-3685	CLIP-seq
MIRT2688568	hsa-miR-3686	CLIP-seq
MIRT2600183	hsa-miR-376c	CLIP-seq
MIRT2600184	hsa-miR-384	CLIP-seq
MIRT1261376	hsa-miR-3915	CLIP-seq
MIRT2600185	hsa-miR-3922-3p	CLIP-seq
MIRT2600186	hsa-miR-3926	CLIP-seq
MIRT1261377	hsa-miR-3938	CLIP-seq
MIRT2600187	hsa-miR-3942-3p	CLIP-seq
MIRT2600188	hsa-miR-3943	CLIP-seq
MIRT2600189	hsa-miR-3978	CLIP-seq
MIRT1552560	hsa-miR-4310	CLIP-seq
MIRT2600190	hsa-miR-4323	CLIP-seq
MIRT2303551	hsa-miR-4328	CLIP-seq
MIRT2600191	hsa-miR-4426	CLIP-seq
MIRT1261401	hsa-miR-4430	CLIP-seq
MIRT2600192	hsa-miR-4434	CLIP-seq
MIRT2600193	hsa-miR-4452	CLIP-seq
MIRT2688569	hsa-miR-4460	CLIP-seq
MIRT1261402	hsa-miR-4473	CLIP-seq
MIRT2600194	hsa-miR-4482	CLIP-seq
MIRT2600195	hsa-miR-4484	CLIP-seq
MIRT2600196	hsa-miR-4496	CLIP-seq
MIRT1261403	hsa-miR-4505	CLIP-seq
MIRT2688570	hsa-miR-4512	CLIP-seq
MIRT1261378	hsa-miR-4514	CLIP-seq
MIRT1261379	hsa-miR-4515	CLIP-seq
MIRT2600197	hsa-miR-4516	CLIP-seq
MIRT2600198	hsa-miR-4531	CLIP-seq
MIRT2688571	hsa-miR-4533	CLIP-seq
MIRT2600199	hsa-miR-4537	CLIP-seq
MIRT2600200	hsa-miR-4647	CLIP-seq
MIRT2600201	hsa-miR-4653-3p	CLIP-seq
MIRT2600202	hsa-miR-4662b	CLIP-seq
MIRT2600203	hsa-miR-4666-3p	CLIP-seq
MIRT2600204	hsa-miR-4666-5p	CLIP-seq
MIRT2432259	hsa-miR-4685-5p	CLIP-seq
MIRT2600205	hsa-miR-4686	CLIP-seq
MIRT1261381	hsa-miR-4689	CLIP-seq
MIRT1261382	hsa-miR-4692	CLIP-seq
MIRT2600206	hsa-miR-4698	CLIP-seq
MIRT1261405	hsa-miR-4704-5p	CLIP-seq
MIRT2688572	hsa-miR-4727-3p	CLIP-seq
MIRT2432260	hsa-miR-4729	CLIP-seq
MIRT2600207	hsa-miR-4735-5p	CLIP-seq
MIRT2688573	hsa-miR-4747-5p	CLIP-seq
MIRT1261384	hsa-miR-4751	CLIP-seq
MIRT2600208	hsa-miR-4753-5p	CLIP-seq
MIRT1261385	hsa-miR-4755-5p	CLIP-seq
MIRT2600209	hsa-miR-4757-5p	CLIP-seq
MIRT2600210	hsa-miR-4758-3p	CLIP-seq
MIRT1261386	hsa-miR-4763-3p	CLIP-seq
MIRT1261387	hsa-miR-4780	CLIP-seq
MIRT2432261	hsa-miR-4789-5p	CLIP-seq
MIRT2600211	hsa-miR-4797-5p	CLIP-seq
MIRT2600212	hsa-miR-4802-3p	CLIP-seq
MIRT1261406	hsa-miR-4803	CLIP-seq
MIRT2600213	hsa-miR-494	CLIP-seq
MIRT2600214	hsa-miR-502-5p	CLIP-seq
MIRT2600215	hsa-miR-506	CLIP-seq
MIRT2600216	hsa-miR-5096	CLIP-seq
MIRT1261407	hsa-miR-512-3p	CLIP-seq
MIRT2600217	hsa-miR-513b	CLIP-seq
MIRT2600218	hsa-miR-515-5p	CLIP-seq
MIRT1261408	hsa-miR-520d-5p	CLIP-seq
MIRT1261409	hsa-miR-520f	CLIP-seq
MIRT1261410	hsa-miR-524-5p	CLIP-seq
MIRT2600219	hsa-miR-539	CLIP-seq
MIRT2688574	hsa-miR-542-3p	CLIP-seq
MIRT1261388	hsa-miR-548aa	CLIP-seq
MIRT2600220	hsa-miR-548an	CLIP-seq
MIRT2600221	hsa-miR-548c-3p	CLIP-seq
MIRT2600222	hsa-miR-548s	CLIP-seq
MIRT2600223	hsa-miR-569	CLIP-seq
MIRT2432264	hsa-miR-582-5p	CLIP-seq
MIRT2600224	hsa-miR-583	CLIP-seq
MIRT2600226	hsa-miR-600	CLIP-seq
MIRT2600227	hsa-miR-607	CLIP-seq
MIRT2600228	hsa-miR-616	CLIP-seq
MIRT2600229	hsa-miR-619	CLIP-seq
MIRT2600230	hsa-miR-620	CLIP-seq
MIRT1261392	hsa-miR-623	CLIP-seq
MIRT2600231	hsa-miR-628-5p	CLIP-seq
MIRT2688575	hsa-miR-633	CLIP-seq
MIRT2432265	hsa-miR-644	CLIP-seq
MIRT2600232	hsa-miR-646	CLIP-seq
MIRT2600233	hsa-miR-659	CLIP-seq
MIRT2600234	hsa-miR-767-3p	CLIP-seq
MIRT1261411	hsa-miR-767-5p	CLIP-seq
MIRT2600235	hsa-miR-802	CLIP-seq
MIRT1261394	hsa-miR-875-3p	CLIP-seq
MIRT2600236	hsa-miR-888	CLIP-seq
MIRT2432266	hsa-miR-889	CLIP-seq
MIRT1261395	hsa-miR-940	CLIP-seq

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001843	Process	Neural tube closure	IMP	21901791
GO:0005515	Function	Protein binding	IPI	14645515, 16417580, 16442230, 17030191, 18922795, 18976727, 25416956, 25910212, 32296183
GO:0005634	Component	Nucleus	IDA	14645515, 16417580, 18922795
GO:0005829	Component	Cytosol	IDA	14645515, 18922795
GO:0005829	Component	Cytosol	TAS
GO:0006606	Process	Protein import into nucleus	IDA	21199191
GO:0006606	Process	Protein import into nucleus	IMP	14645515, 16417580
GO:0008270	Function	Zinc ion binding	IEA
GO:0031398	Process	Positive regulation of protein ubiquitination	IDA	17030191
GO:0031965	Component	Nuclear membrane	IDA	14645515, 16417580
GO:0032436	Process	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IDA	17030191
GO:0035904	Process	Aorta development	IEA
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IDA	17030191
GO:0060071	Process	Wnt signaling pathway, planar cell polarity pathway	NAS	24431302
GO:0060976	Process	Coronary vasculature development	IEA
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IDA	17030191
GO:2000691	Process	Negative regulation of cardiac muscle cell myoblast differentiation	IDA	21199191

MIM	HGNC	e!Ensembl
608500	17019	ENSG00000139174

Protein

UniProt ID

Q96MT3

Protein name

Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1)

Protein function

Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalat

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06297	PET	31 → 115	PET Domain	Domain
PF00412	LIM	126 → 186	LIM domain	Domain
PF00412	LIM	191 → 247	LIM domain	Domain
PF00412	LIM	251 → 309	LIM domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia). {ECO:0000269|PubMed:12525887, ECO:00002

Sequence

MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS

Sequence length

831

Interactions

View interactions

	KEGG		Reactome
	Wnt signaling pathway		Asymmetric localization of PCP proteins

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315 View all (1024 more)
Proteasome-associated autoinflammatory syndrome	Prickle1-Related Progressive Myoclonus Epilepsy with Ataxia	rs387906680, rs146254972, rs1555257073, rs1554239543, rs1553209362, rs1553209373, rs1555257075, rs1555257076, rs748082671	21276947, 18976727
Myoclonic epilepsy	Unverricht-Lundborg disease, Unverricht-Lundborg Syndrome	rs267607103, rs267607104, rs147484110, rs74315442, rs74315443, rs121909346, rs121918622, rs121918623, rs121917954, rs121917955, rs1574272192, rs121918624, rs121918625, rs121918628, rs121918629 View all (378 more)	18976727

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Source
Unknown
Epilepsy	epilepsy, progressive myoclonic, 1B, progressive myoclonus epilepsy, epilepsy	GenCC
Myoclonic Epilepsy	Unverricht-Lundborg syndrome	GenCC
Multiple Sclerosis	Multiple Sclerosis	GWAS

Show/Hide Text Mining Associations (22)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenoma	Associate	27245242
Agenesis of Corpus Callosum	Associate	26727662
Ataxia	Associate	18976727
Autism Spectrum Disorder	Associate	29790814
Breast Neoplasms	Associate	26939613, 27184734
Colonic Neoplasms	Associate	27245242
Colorectal Neoplasms	Associate	27245242
Developmental Disabilities	Associate	29790814
Diabetes Mellitus Type 2	Associate	19252133
Epilepsies Myoclonic	Associate	26727662, 29790814
Epilepsy	Associate	18976727, 26727662, 29790814
Fetal akinesia syndrome X linked	Associate	31680123
Hunt's syndrome	Associate	18976727
Leukemia Myeloid Acute	Associate	34001134
Myoclonic Epilepsies Progressive	Associate	18976727, 31035234
Neoplasm Metastasis	Associate	27184734
Neoplasms	Associate	26939613, 27184734, 34001134
Nervous System Diseases	Associate	31035234
Neurologic Manifestations	Associate	26727662, 29790814
Polymicrogyria	Associate	26727662
Rectal Neoplasms	Associate	34642262
Stomach Neoplasms	Associate	30702489, 39259065

PRICKLE1 (prickle planar cell polarity protein 1)