Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	128178
Gene name	EDAR associated via death domain
Gene symbol	EDARADD
Synonyms (NCBI Gene)	CRECTD11AECTD11BED3EDA3
Chromosome	1
Chromosome location	1q42.3-q43
Summary	This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found

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SNP ID	Visualize variation	Clinical significance	Consequence
rs74315309	G>A	Pathogenic	Missense variant, coding sequence variant
rs121908116	T>G	Pathogenic	Missense variant, coding sequence variant
rs397515575	AACGGT>-	Pathogenic	Coding sequence variant, inframe deletion
rs766500689	C>A,T	Pathogenic	Stop gained, synonymous variant, coding sequence variant
rs879255553	G>A	Pathogenic	Splice donor variant
rs879255629	G>A	Pathogenic	Missense variant, coding sequence variant
rs954823206	G>A	Likely-pathogenic	Coding sequence variant, stop gained
rs1553271837	A>G	Likely-pathogenic	Coding sequence variant, missense variant

529

Show/Hide all (529)

miRTarBase ID	miRNA	Experiments	Reference
MIRT043891	hsa-miR-378a-3p	CLASH	23622248
MIRT040816	hsa-miR-18a-3p	CLASH	23622248
MIRT638797	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT638796	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT638795	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT638794	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT638793	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT638792	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT638791	hsa-miR-3182	HITS-CLIP	23824327
MIRT638790	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT638789	hsa-miR-4284	HITS-CLIP	23824327
MIRT638788	hsa-miR-3686	HITS-CLIP	23824327
MIRT638787	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456954	hsa-miR-4437	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT456952	hsa-miR-4674	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	22012620
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	22012620
MIRT186098	hsa-miR-764	PAR-CLIP	22012620
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT456954	hsa-miR-4437	PAR-CLIP	23446348
MIRT456952	hsa-miR-4674	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	24398324
MIRT186099	hsa-miR-4436a	PAR-CLIP	24398324
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	24398324
MIRT186098	hsa-miR-764	PAR-CLIP	24398324
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT456954	hsa-miR-4437	PAR-CLIP	23592263
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	23592263
MIRT456952	hsa-miR-4674	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186097	hsa-miR-552-3p	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186098	hsa-miR-764	PAR-CLIP	26701625
MIRT186099	hsa-miR-4436a	PAR-CLIP	27292025
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	27292025
MIRT186097	hsa-miR-552-3p	PAR-CLIP	27292025
MIRT186098	hsa-miR-764	PAR-CLIP	27292025
MIRT638797	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT638796	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT638795	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT638794	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT638793	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT638792	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT638791	hsa-miR-3182	HITS-CLIP	23824327
MIRT638790	hsa-miR-103a-2-5p	HITS-CLIP	23824327
MIRT638789	hsa-miR-4284	HITS-CLIP	23824327
MIRT638788	hsa-miR-3686	HITS-CLIP	23824327
MIRT638787	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	20371350
MIRT186099	hsa-miR-4436a	PAR-CLIP	20371350
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	20371350
MIRT186098	hsa-miR-764	PAR-CLIP	20371350
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456954	hsa-miR-4437	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT456952	hsa-miR-4674	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	21572407
MIRT186099	hsa-miR-4436a	PAR-CLIP	21572407
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	21572407
MIRT186098	hsa-miR-764	PAR-CLIP	21572407
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	21572407
MIRT186097	hsa-miR-552-3p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	22012620
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	22012620
MIRT186098	hsa-miR-764	PAR-CLIP	22012620
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	22012620
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23446348
MIRT186099	hsa-miR-4436a	PAR-CLIP	23446348
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23446348
MIRT186098	hsa-miR-764	PAR-CLIP	23446348
MIRT456954	hsa-miR-4437	PAR-CLIP	23446348
MIRT456952	hsa-miR-4674	PAR-CLIP	23446348
MIRT186097	hsa-miR-552-3p	PAR-CLIP	24398324
MIRT186099	hsa-miR-4436a	PAR-CLIP	24398324
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	24398324
MIRT186098	hsa-miR-764	PAR-CLIP	24398324
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT186097	hsa-miR-552-3p	PAR-CLIP	23592263
MIRT186099	hsa-miR-4436a	PAR-CLIP	23592263
MIRT186100	hsa-miR-5000-3p	PAR-CLIP	23592263
MIRT186098	hsa-miR-764	PAR-CLIP	23592263
MIRT456954	hsa-miR-4437	PAR-CLIP	23592263
MIRT456953	hsa-miR-4639-5p	PAR-CLIP	23592263
MIRT456952	hsa-miR-4674	PAR-CLIP	23592263
MIRT952018	hsa-miR-1237	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT952020	hsa-miR-193a-3p	CLIP-seq
MIRT952021	hsa-miR-193b	CLIP-seq
MIRT952022	hsa-miR-2355-5p	CLIP-seq
MIRT952023	hsa-miR-28-5p	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT952025	hsa-miR-3139	CLIP-seq
MIRT952026	hsa-miR-3150b-3p	CLIP-seq
MIRT952027	hsa-miR-3185	CLIP-seq
MIRT952028	hsa-miR-3187-3p	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT952030	hsa-miR-323b-5p	CLIP-seq
MIRT952031	hsa-miR-3613-5p	CLIP-seq
MIRT952032	hsa-miR-3926	CLIP-seq
MIRT952033	hsa-miR-4267	CLIP-seq
MIRT952034	hsa-miR-4268	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT952036	hsa-miR-4330	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT952038	hsa-miR-4480	CLIP-seq
MIRT952039	hsa-miR-4487	CLIP-seq
MIRT952040	hsa-miR-4511	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT952043	hsa-miR-4689	CLIP-seq
MIRT952044	hsa-miR-4701-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT952046	hsa-miR-4727-5p	CLIP-seq
MIRT952047	hsa-miR-4728-3p	CLIP-seq
MIRT952048	hsa-miR-4757-5p	CLIP-seq
MIRT952049	hsa-miR-4769-3p	CLIP-seq
MIRT952050	hsa-miR-4784	CLIP-seq
MIRT952051	hsa-miR-4793-3p	CLIP-seq
MIRT952052	hsa-miR-4793-5p	CLIP-seq
MIRT952053	hsa-miR-518e	CLIP-seq
MIRT952054	hsa-miR-548s	CLIP-seq
MIRT952055	hsa-miR-588	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT952058	hsa-miR-708	CLIP-seq
MIRT952059	hsa-miR-769-5p	CLIP-seq
MIRT952060	hsa-miR-890	CLIP-seq
MIRT952061	hsa-miR-125a-5p	CLIP-seq
MIRT952062	hsa-miR-125b	CLIP-seq
MIRT952063	hsa-miR-127-5p	CLIP-seq
MIRT952064	hsa-miR-1276	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT952065	hsa-miR-135a	CLIP-seq
MIRT952066	hsa-miR-135b	CLIP-seq
MIRT952067	hsa-miR-184	CLIP-seq
MIRT952068	hsa-miR-1976	CLIP-seq
MIRT952069	hsa-miR-29a	CLIP-seq
MIRT952070	hsa-miR-29b	CLIP-seq
MIRT952071	hsa-miR-29c	CLIP-seq
MIRT952072	hsa-miR-3120-5p	CLIP-seq
MIRT952073	hsa-miR-3130-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT952075	hsa-miR-3192	CLIP-seq
MIRT952076	hsa-miR-323-5p	CLIP-seq
MIRT952077	hsa-miR-3619-3p	CLIP-seq
MIRT952078	hsa-miR-3622b-5p	CLIP-seq
MIRT952079	hsa-miR-3664-5p	CLIP-seq
MIRT952080	hsa-miR-3675-3p	CLIP-seq
MIRT952081	hsa-miR-3689a-3p	CLIP-seq
MIRT952082	hsa-miR-3689c	CLIP-seq
MIRT952083	hsa-miR-4292	CLIP-seq
MIRT952084	hsa-miR-4308	CLIP-seq
MIRT952085	hsa-miR-4319	CLIP-seq
MIRT952086	hsa-miR-4327	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT952087	hsa-miR-4475	CLIP-seq
MIRT952088	hsa-miR-4639-3p	CLIP-seq
MIRT952089	hsa-miR-4640-5p	CLIP-seq
MIRT952090	hsa-miR-4652-3p	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT952091	hsa-miR-4670-3p	CLIP-seq
MIRT952092	hsa-miR-4680-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT952093	hsa-miR-4720-5p	CLIP-seq
MIRT952094	hsa-miR-4726-5p	CLIP-seq
MIRT952095	hsa-miR-4728-5p	CLIP-seq
MIRT952096	hsa-miR-4732-3p	CLIP-seq
MIRT952097	hsa-miR-4751	CLIP-seq
MIRT952098	hsa-miR-4799-3p	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT952100	hsa-miR-490-5p	CLIP-seq
MIRT952101	hsa-miR-526b	CLIP-seq
MIRT952102	hsa-miR-580	CLIP-seq
MIRT952103	hsa-miR-591	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT952104	hsa-miR-661	CLIP-seq
MIRT952105	hsa-miR-670	CLIP-seq
MIRT952106	hsa-miR-876-3p	CLIP-seq
MIRT952061	hsa-miR-125a-5p	CLIP-seq
MIRT952062	hsa-miR-125b	CLIP-seq
MIRT952063	hsa-miR-127-5p	CLIP-seq
MIRT952064	hsa-miR-1276	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT952065	hsa-miR-135a	CLIP-seq
MIRT952066	hsa-miR-135b	CLIP-seq
MIRT1548131	hsa-miR-1827	CLIP-seq
MIRT952068	hsa-miR-1976	CLIP-seq
MIRT952022	hsa-miR-2355-5p	CLIP-seq
MIRT1548132	hsa-miR-2682	CLIP-seq
MIRT952069	hsa-miR-29a	CLIP-seq
MIRT952070	hsa-miR-29b	CLIP-seq
MIRT952071	hsa-miR-29c	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT952073	hsa-miR-3130-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT952075	hsa-miR-3192	CLIP-seq
MIRT1548133	hsa-miR-3612	CLIP-seq
MIRT952077	hsa-miR-3619-3p	CLIP-seq
MIRT952078	hsa-miR-3622b-5p	CLIP-seq
MIRT952081	hsa-miR-3689a-3p	CLIP-seq
MIRT952082	hsa-miR-3689c	CLIP-seq
MIRT1548134	hsa-miR-3945	CLIP-seq
MIRT1548135	hsa-miR-4253	CLIP-seq
MIRT1548136	hsa-miR-4273	CLIP-seq
MIRT1548137	hsa-miR-4289	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT952085	hsa-miR-4319	CLIP-seq
MIRT952086	hsa-miR-4327	CLIP-seq
MIRT1548138	hsa-miR-4328	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT1548139	hsa-miR-4459	CLIP-seq
MIRT1548140	hsa-miR-4468	CLIP-seq
MIRT952087	hsa-miR-4475	CLIP-seq
MIRT1548141	hsa-miR-449c	CLIP-seq
MIRT952089	hsa-miR-4640-5p	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT952091	hsa-miR-4670-3p	CLIP-seq
MIRT1548142	hsa-miR-4677-3p	CLIP-seq
MIRT1548143	hsa-miR-4677-5p	CLIP-seq
MIRT1548144	hsa-miR-4679	CLIP-seq
MIRT952092	hsa-miR-4680-5p	CLIP-seq
MIRT1548145	hsa-miR-4695-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT1548146	hsa-miR-4722-5p	CLIP-seq
MIRT952094	hsa-miR-4726-5p	CLIP-seq
MIRT952095	hsa-miR-4728-5p	CLIP-seq
MIRT952096	hsa-miR-4732-3p	CLIP-seq
MIRT952097	hsa-miR-4751	CLIP-seq
MIRT1548147	hsa-miR-4753-3p	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT1548148	hsa-miR-572	CLIP-seq
MIRT952103	hsa-miR-591	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT1548149	hsa-miR-650	CLIP-seq
MIRT952104	hsa-miR-661	CLIP-seq
MIRT952105	hsa-miR-670	CLIP-seq
MIRT952060	hsa-miR-890	CLIP-seq
MIRT1548150	hsa-miR-924	CLIP-seq
MIRT1548151	hsa-miR-942	CLIP-seq
MIRT952068	hsa-miR-1976	CLIP-seq
MIRT952023	hsa-miR-28-5p	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT952073	hsa-miR-3130-3p	CLIP-seq
MIRT952025	hsa-miR-3139	CLIP-seq
MIRT952026	hsa-miR-3150b-3p	CLIP-seq
MIRT1981942	hsa-miR-3158-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT1981943	hsa-miR-3180-5p	CLIP-seq
MIRT952027	hsa-miR-3185	CLIP-seq
MIRT952028	hsa-miR-3187-3p	CLIP-seq
MIRT952075	hsa-miR-3192	CLIP-seq
MIRT952030	hsa-miR-323b-5p	CLIP-seq
MIRT952031	hsa-miR-3613-5p	CLIP-seq
MIRT1981944	hsa-miR-3614-3p	CLIP-seq
MIRT952077	hsa-miR-3619-3p	CLIP-seq
MIRT952081	hsa-miR-3689a-3p	CLIP-seq
MIRT952082	hsa-miR-3689c	CLIP-seq
MIRT952032	hsa-miR-3926	CLIP-seq
MIRT1981945	hsa-miR-421	CLIP-seq
MIRT952033	hsa-miR-4267	CLIP-seq
MIRT952034	hsa-miR-4268	CLIP-seq
MIRT1548136	hsa-miR-4273	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT1548138	hsa-miR-4328	CLIP-seq
MIRT952036	hsa-miR-4330	CLIP-seq
MIRT952037	hsa-miR-4435	CLIP-seq
MIRT1981946	hsa-miR-4470	CLIP-seq
MIRT952039	hsa-miR-4487	CLIP-seq
MIRT952040	hsa-miR-4511	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT952091	hsa-miR-4670-3p	CLIP-seq
MIRT1548142	hsa-miR-4677-3p	CLIP-seq
MIRT1548143	hsa-miR-4677-5p	CLIP-seq
MIRT1548144	hsa-miR-4679	CLIP-seq
MIRT952092	hsa-miR-4680-5p	CLIP-seq
MIRT952043	hsa-miR-4689	CLIP-seq
MIRT952044	hsa-miR-4701-5p	CLIP-seq
MIRT1981947	hsa-miR-4722-3p	CLIP-seq
MIRT952095	hsa-miR-4728-5p	CLIP-seq
MIRT952097	hsa-miR-4751	CLIP-seq
MIRT1548147	hsa-miR-4753-3p	CLIP-seq
MIRT1981948	hsa-miR-4762-3p	CLIP-seq
MIRT1981949	hsa-miR-4763-5p	CLIP-seq
MIRT952050	hsa-miR-4784	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT952053	hsa-miR-518e	CLIP-seq
MIRT1981950	hsa-miR-520a-5p	CLIP-seq
MIRT1981951	hsa-miR-525-5p	CLIP-seq
MIRT952054	hsa-miR-548s	CLIP-seq
MIRT952055	hsa-miR-588	CLIP-seq
MIRT952103	hsa-miR-591	CLIP-seq
MIRT952058	hsa-miR-708	CLIP-seq
MIRT952060	hsa-miR-890	CLIP-seq
MIRT1548151	hsa-miR-942	CLIP-seq
MIRT952018	hsa-miR-1237	CLIP-seq
MIRT2216811	hsa-miR-1245b-5p	CLIP-seq
MIRT2216812	hsa-miR-125a-3p	CLIP-seq
MIRT2216813	hsa-miR-1260	CLIP-seq
MIRT2216814	hsa-miR-1260b	CLIP-seq
MIRT952019	hsa-miR-1285	CLIP-seq
MIRT2216815	hsa-miR-134	CLIP-seq
MIRT2216816	hsa-miR-185	CLIP-seq
MIRT2216817	hsa-miR-188-3p	CLIP-seq
MIRT952020	hsa-miR-193a-3p	CLIP-seq
MIRT952021	hsa-miR-193b	CLIP-seq
MIRT2216818	hsa-miR-214	CLIP-seq
MIRT952069	hsa-miR-29a	CLIP-seq
MIRT952070	hsa-miR-29b	CLIP-seq
MIRT952071	hsa-miR-29c	CLIP-seq
MIRT952024	hsa-miR-3074-5p	CLIP-seq
MIRT2216819	hsa-miR-3118	CLIP-seq
MIRT2216820	hsa-miR-3136-5p	CLIP-seq
MIRT2216821	hsa-miR-3142	CLIP-seq
MIRT2216822	hsa-miR-3156-3p	CLIP-seq
MIRT1981942	hsa-miR-3158-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT952029	hsa-miR-3187-5p	CLIP-seq
MIRT2216823	hsa-miR-3619-5p	CLIP-seq
MIRT2216824	hsa-miR-383	CLIP-seq
MIRT1981945	hsa-miR-421	CLIP-seq
MIRT2216825	hsa-miR-4291	CLIP-seq
MIRT952035	hsa-miR-4303	CLIP-seq
MIRT2216826	hsa-miR-4306	CLIP-seq
MIRT2216827	hsa-miR-4320	CLIP-seq
MIRT2216828	hsa-miR-4433	CLIP-seq
MIRT2216829	hsa-miR-4439	CLIP-seq
MIRT1548139	hsa-miR-4459	CLIP-seq
MIRT2216830	hsa-miR-4513	CLIP-seq
MIRT2216831	hsa-miR-4644	CLIP-seq
MIRT2216832	hsa-miR-4645-5p	CLIP-seq
MIRT952041	hsa-miR-4649-3p	CLIP-seq
MIRT2216833	hsa-miR-4650-5p	CLIP-seq
MIRT2216834	hsa-miR-4654	CLIP-seq
MIRT952042	hsa-miR-4660	CLIP-seq
MIRT2216835	hsa-miR-4673	CLIP-seq
MIRT2216836	hsa-miR-4676-5p	CLIP-seq
MIRT2216837	hsa-miR-4691-5p	CLIP-seq
MIRT952045	hsa-miR-4709-3p	CLIP-seq
MIRT2216838	hsa-miR-4709-5p	CLIP-seq
MIRT2216839	hsa-miR-4733-3p	CLIP-seq
MIRT1981949	hsa-miR-4763-5p	CLIP-seq
MIRT2216840	hsa-miR-4768-3p	CLIP-seq
MIRT2216841	hsa-miR-4769-5p	CLIP-seq
MIRT2216842	hsa-miR-4772-5p	CLIP-seq
MIRT952051	hsa-miR-4793-3p	CLIP-seq
MIRT952052	hsa-miR-4793-5p	CLIP-seq
MIRT2216843	hsa-miR-575	CLIP-seq
MIRT952056	hsa-miR-612	CLIP-seq
MIRT2216844	hsa-miR-619	CLIP-seq
MIRT952057	hsa-miR-646	CLIP-seq
MIRT2216845	hsa-miR-662	CLIP-seq
MIRT2216846	hsa-miR-761	CLIP-seq
MIRT952059	hsa-miR-769-5p	CLIP-seq
MIRT2216847	hsa-miR-922	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT952099	hsa-miR-487a	CLIP-seq
MIRT2216815	hsa-miR-134	CLIP-seq
MIRT2216819	hsa-miR-3118	CLIP-seq
MIRT2216820	hsa-miR-3136-5p	CLIP-seq
MIRT1981942	hsa-miR-3158-3p	CLIP-seq
MIRT952074	hsa-miR-3179	CLIP-seq
MIRT2216829	hsa-miR-4439	CLIP-seq
MIRT2216830	hsa-miR-4513	CLIP-seq
MIRT1981949	hsa-miR-4763-5p	CLIP-seq
MIRT2520853	hsa-miR-3155	CLIP-seq
MIRT2520854	hsa-miR-3155b	CLIP-seq
MIRT2520855	hsa-miR-4536	CLIP-seq
MIRT2520856	hsa-miR-484	CLIP-seq
MIRT1548148	hsa-miR-572	CLIP-seq
MIRT2520853	hsa-miR-3155	CLIP-seq
MIRT2520854	hsa-miR-3155b	CLIP-seq
MIRT2679747	hsa-miR-4323	CLIP-seq
MIRT2520855	hsa-miR-4536	CLIP-seq
MIRT2679748	hsa-miR-4726-3p	CLIP-seq
MIRT2216839	hsa-miR-4733-3p	CLIP-seq
MIRT2679749	hsa-miR-4758-3p	CLIP-seq
MIRT2520856	hsa-miR-484	CLIP-seq
MIRT1548148	hsa-miR-572	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 31515488
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0030154	Process	Cell differentiation	IEA

MIM	HGNC	e!Ensembl
606603	14341	ENSG00000186197

Q8WWZ3

Protein name

Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog)

Protein function

Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00531	Death	122 → 199	Death domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis.

Sequence

MGLRTTKQMGRGTKAPGHQEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTI
TLNCPRNSDMKNQGEENGFPDSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQD
LLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLM
ELCRLYHRADVEKVLRRWVDEEWPKRERGDPSRHF

Sequence length

215

Interactions

View interactions

	KEGG		Reactome
	NF-kappa B signaling pathway		TNFs bind their physiological receptors

227

Show/Hide Causal Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant	Likely pathogenic; Pathogenic	rs74315309, rs121908116	RCV001729334 RCV000055985
Ectodermal dysplasia 11A, hypohidrotic/hair/tooth type, autosomal dominant	Likely pathogenic; Pathogenic	rs2103042605, rs74315309, rs121908116, rs879255629, rs2526890961, rs954823206	RCV001807985 RCV004798715 RCV000004408 RCV003765486 RCV003794981 RCV000549383
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT	Likely pathogenic	rs879255629	RCV000239549
Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type, autosomal recessive	Likely pathogenic; Pathogenic	rs74315309, rs2526927321, rs879255629, rs879255553, rs766500689, rs2526890961, rs954823206, rs1657345576, rs200017138	RCV000004407 RCV003238157 RCV003765486 RCV000239464 RCV003338495 RCV003794981 RCV000549383 RCV001291625 RCV001291626
Tooth agenesis	Likely pathogenic	rs1030214435	RCV001269383

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Ectodermal dysplasia	Benign; Likely benign	rs114632254	RCV005400721
Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type, autosomal recessive	Likely benign; Uncertain significance	rs61740486, rs61740488, rs1309549108, rs988277282, rs111987152	RCV000276600 RCV000369022 RCV001098734 RCV001102495 RCV001098850
EDARADD-related disorder	Benign	rs139996586	RCV003953175
Familial cancer of breast	Conflicting classifications of pathogenicity	rs189781826	RCV005891667
Gastric cancer	Benign	rs634626	RCV005925222
Hypohidrotic ectodermal dysplasia	Uncertain significance; Benign; Likely benign; Conflicting classifications of pathogenicity	rs483352767, rs79233817, rs966365, rs184596437, rs114632254, rs604070, rs60808129, rs375789023, rs760609411, rs189781826, rs886046194, rs7513402, rs878897423, rs6428955, rs878900513 View all (46 more)	RCV001102402 RCV001100438 RCV001100439 RCV001100444 RCV001102398 RCV001102399 RCV001100440 RCV001102401 RCV001097001 RCV001097004 RCV001102496 RCV001097089 RCV001098844 RCV001098845 RCV001098847 RCV001100441 RCV001097002 RCV001098735 RCV001100548 RCV001097090 RCV001097091 RCV001097092 RCV001098848 RCV001100661 RCV001100664 RCV001102397 RCV001096998 RCV001096999 RCV001097000 RCV001098736 RCV001100553 RCV001100554 RCV001102501 RCV001097087 RCV001100663 RCV001102396 RCV001102403 RCV001097003 RCV001098737 RCV001100550 RCV001097088 RCV001098849 RCV001102400 RCV001096997 RCV001098738 RCV001098739 RCV001100549 RCV001100551 RCV001100552 RCV001100555 RCV001102494 RCV001102497 RCV001102498 RCV001102499 RCV001102500 RCV001097093 RCV001097094 RCV001098843 RCV001098846 RCV001100662 RCV001100442 RCV001100443
Hypohidrotic Ectodermal Dysplasia, Recessive	Benign; Likely benign; Conflicting classifications of pathogenicity; Uncertain significance	rs79233817, rs966365, rs184596437, rs604070, rs60808129, rs375789023, rs760609411, rs189781826, rs183153044, rs886046194, rs7513402, rs878897423, rs6428955, rs878900513, rs759461234 View all (29 more)	RCV000353307 RCV000262285 RCV000293938 RCV000288299 RCV000319731 RCV000345575 RCV000304003 RCV000356260 RCV000330735 RCV000340693 RCV000300675 RCV000370341 RCV000268785 RCV000307413 RCV000385891 RCV000361021 RCV000400334 RCV000263791 RCV000270882 RCV000348580 RCV000389958 RCV000313375 RCV000364479 RCV000320698 RCV000266882 RCV000371747 RCV000389636 RCV000291908 RCV000339894 RCV000398160 RCV000334007 RCV000384811 RCV000283309 RCV000379160 RCV000335136 RCV000377749 RCV000332712 RCV000398173 RCV000298052 RCV000381618 RCV000327972 RCV000286993 RCV000397258 RCV000272688 RCV000324071
Lung cancer	Benign; Conflicting classifications of pathogenicity	rs634626, rs189781826	RCV005925224 RCV005891668
Malignant tumor of esophagus	Conflicting classifications of pathogenicity	rs114783553	RCV005891669
Thymoma	Conflicting classifications of pathogenicity	rs114783553	RCV005891670
Uterine carcinosarcoma	Benign	rs634626	RCV005925223

Show/Hide Text Mining Associations (13)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Anodontia	Associate	22581971, 27665865
Carcinoma Non Small Cell Lung	Associate	26449251
Colorectal Neoplasms	Stimulate	37838280
Dental Caries	Associate	21940522, 39543892
Ectodermal Dysplasia	Associate	22581971, 30974434, 34573371, 37673591
Ectodermal Dysplasia 1 Anhidrotic	Associate	33205897
Ectodermal Dysplasia Hypohidrotic Autosomal Recessive	Associate	30974434
Genetic Diseases Inborn	Associate	37673591
Neoplasms	Associate	32188493
Neural crest tumor	Associate	31796081
Oropharyngeal Neoplasms	Associate	37175405
Prostatic Neoplasms	Associate	32188493
Triple Negative Breast Neoplasms	Associate	36335337

EDARADD (EDAR associated via death domain)