OSCP1 (organic solute carrier partner 1)

Gene

• Entrez ID: 127700
• Gene name: Organic solute carrier partner 1
• Gene symbol: OSCP1
• Synonyms (NCBI Gene): C1orf102, NOR1
• Chromosome: 1
• Chromosome location: 1p34.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT035529	hsa-miR-638	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23554459
MIRT035529	hsa-miR-638	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23554459
MIRT646709	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT646708	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT646707	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT646706	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT646705	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT646709	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT646708	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT646707	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT646706	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT646705	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT2287824	hsa-miR-338-3p	CLIP-seq
MIRT2287825	hsa-miR-4530	CLIP-seq
MIRT2585945	hsa-miR-103a	CLIP-seq
MIRT2585946	hsa-miR-107	CLIP-seq
MIRT2585947	hsa-miR-1285	CLIP-seq
MIRT2585948	hsa-miR-135a	CLIP-seq
MIRT2585949	hsa-miR-135b	CLIP-seq
MIRT2585950	hsa-miR-15a	CLIP-seq
MIRT2585951	hsa-miR-15b	CLIP-seq
MIRT2585952	hsa-miR-16	CLIP-seq
MIRT2585953	hsa-miR-1915	CLIP-seq
MIRT2585954	hsa-miR-195	CLIP-seq
MIRT2585955	hsa-miR-199a-3p	CLIP-seq
MIRT2585956	hsa-miR-199b-3p	CLIP-seq
MIRT2585957	hsa-miR-2355-5p	CLIP-seq
MIRT2585958	hsa-miR-3121-3p	CLIP-seq
MIRT2585959	hsa-miR-3129-5p	CLIP-seq
MIRT2585960	hsa-miR-3187-5p	CLIP-seq
MIRT2585961	hsa-miR-3675-5p	CLIP-seq
MIRT2585962	hsa-miR-377	CLIP-seq
MIRT2585963	hsa-miR-378g	CLIP-seq
MIRT2585964	hsa-miR-424	CLIP-seq
MIRT2585965	hsa-miR-4314	CLIP-seq
MIRT2585966	hsa-miR-4486	CLIP-seq
MIRT2585967	hsa-miR-4524	CLIP-seq
MIRT2585968	hsa-miR-4640-5p	CLIP-seq
MIRT2585969	hsa-miR-4726-5p	CLIP-seq
MIRT2585970	hsa-miR-4797-3p	CLIP-seq
MIRT2585971	hsa-miR-4803	CLIP-seq
MIRT2585972	hsa-miR-486-3p	CLIP-seq
MIRT2585973	hsa-miR-497	CLIP-seq
MIRT2585974	hsa-miR-503	CLIP-seq
MIRT2585975	hsa-miR-612	CLIP-seq
MIRT2585976	hsa-miR-646	CLIP-seq
MIRT2585977	hsa-miR-936	CLIP-seq
MIRT2585948	hsa-miR-135a	CLIP-seq
MIRT2585949	hsa-miR-135b	CLIP-seq
MIRT2585955	hsa-miR-199a-3p	CLIP-seq
MIRT2585956	hsa-miR-199b-3p	CLIP-seq
MIRT2585958	hsa-miR-3121-3p	CLIP-seq
MIRT2585959	hsa-miR-3129-5p	CLIP-seq
MIRT2585962	hsa-miR-377	CLIP-seq
MIRT2585970	hsa-miR-4797-3p	CLIP-seq
MIRT2585971	hsa-miR-4803	CLIP-seq
MIRT2585977	hsa-miR-936	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IDA	19727524
GO:0009925	Component	Basal plasma membrane	IDA	16006562
GO:0022857	Function	Transmembrane transporter activity	IMP	16006562
GO:1990961	Process	Xenobiotic detoxification by transmembrane export across the plasma membrane	IMP	16006562

Other IDs

• MIM: 608854
• HGNC: 29971
• e!Ensembl: ENSG00000116885

Protein

• UniProt ID: Q8WVF1
• Protein name: Protein OSCP1 (hOSCP1) (Organic solute transport protein 1) (Oxidored-nitro domain-containing protein 1)
• Protein function: May be involved in drug clearance in the placenta.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10188	Oscp1	17 → 199	Organic solute transport protein 1	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed predominantly in testis, also found in placenta and to a lesser extent in thymus and small intestine; abundantly expressed in tumor-derived cell lines (PubMed:16006562). Ubiquitously expressed (PubMed:12819961). {ECO:0000269|
• Sequence:

  MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARKDEWTEVDRKRVLNDIISTMFNRK
  FMEELFKPQELYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKD
  VLLVTFNHLDTIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLH
  IRVSMFLKDKVQNNNGRFVLPVSGPVPWGTEVPGLIRMFNNKGEEVKRIEFKHGGNYVPA
  PKEGSFELYGDRVLKLGTNMYSVNQPVETHVSGSSKNLASWTQESIAPNPLAKEELNFLA
  RLMGGMEIKKPSGPEPGFRLNLFTTDEEEEQAALTRPEELSYEVINIQATQDQQRSEELA
  RIMGEFEITEQPRLSTSKGDDLLAMMDEL

• Sequence length: 389

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	27846195

Unknown
Disease term	Disease name	Evidence	References	Source
Diabetic Retinopathy	Diabetic Retinopathy			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Hepatocellular	Associate	29135101, 36918874
Glioblastoma	Associate	37962027
Neoplasms	Inhibit	37962027