Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	126133
Gene name Gene Name - the full gene name approved by the HGNC.	Aldehyde dehydrogenase 16 family member A1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ALDH16A1
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.33
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and z

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miRTarBase ID	miRNA	Experiments	Reference
MIRT045250	hsa-miR-186-5p	CLASH	23622248
MIRT035869	hsa-miR-1247-5p	CLASH	23622248
MIRT776895	hsa-miR-4269	CLIP-seq
MIRT776896	hsa-miR-4514	CLIP-seq
MIRT776897	hsa-miR-4692	CLIP-seq
MIRT776898	hsa-miR-4698	CLIP-seq
MIRT776899	hsa-miR-4742-5p	CLIP-seq
MIRT776900	hsa-miR-1185	CLIP-seq
MIRT776901	hsa-miR-1225-3p	CLIP-seq
MIRT776902	hsa-miR-1227	CLIP-seq
MIRT776903	hsa-miR-1233	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776905	hsa-miR-1827	CLIP-seq
MIRT776906	hsa-miR-188-5p	CLIP-seq
MIRT776907	hsa-miR-3605-5p	CLIP-seq
MIRT776908	hsa-miR-3679-5p	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776910	hsa-miR-4323	CLIP-seq
MIRT776911	hsa-miR-4661-3p	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776913	hsa-miR-4780	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776915	hsa-miR-623	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq
MIRT776902	hsa-miR-1227	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq
MIRT2170084	hsa-miR-323-5p	CLIP-seq
MIRT2170085	hsa-miR-3934	CLIP-seq
MIRT2170086	hsa-miR-485-5p	CLIP-seq
MIRT2170087	hsa-miR-654-3p	CLIP-seq
MIRT2170088	hsa-miR-876-3p	CLIP-seq
MIRT776902	hsa-miR-1227	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq
MIRT776902	hsa-miR-1227	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq
MIRT776904	hsa-miR-1262	CLIP-seq
MIRT776909	hsa-miR-4252	CLIP-seq
MIRT776912	hsa-miR-4701-3p	CLIP-seq
MIRT776914	hsa-miR-542-3p	CLIP-seq
MIRT776916	hsa-miR-661	CLIP-seq
MIRT776917	hsa-miR-766	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0016020	Component	Membrane	HDA	19946888
GO:0016620	Function	Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA

MIM	HGNC	e!Ensembl
613358	28114	ENSG00000161618

Protein

UniProt ID

Q8IZ83

Protein name

Aldehyde dehydrogenase family 16 member A1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00171	Aldedh	48 → 488	Aldehyde dehydrogenase family	Family
PF00171	Aldedh	539 → 774	Aldehyde dehydrogenase family	Family

Sequence

MAATRAGPRAREIFTSLEYGPVPESHACALAWLDTQDRCLGHYVNGKWLKPEHRNSVPCQ
DPITGENLASCLQAQAEDVAAAVEAARMAFKGWSAHPGVVRAQHLTRLAEVIQKHQRLLW
TLESLVTGRAVREVRDGDVQLAQQLLHYHAIQASTQEEALAGWEPMGVIGLILPPTFSFL
EMMWRICPALAVGCTVVALVPPASPAPLLLAQLAGELGPFPGILNVLSGPASLVPILASQ
PGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESLLLLTDTADVDSAVEGVVDAAWS
DRGPGGLRLLIQESVWDEAMRRLQERMGRLRSGRGLDGAVDMGARGAAACDLVQRFVREA
QSQGAQVFQAGDVPSERPFYPPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVAN
GTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDG
LYEYLRPSGTPARLSCLSKNLNYDTFGLAVPSTLPAGPEIGPSPAPPYGLFVGGRFQAPG
ARSSRPIRDSSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALE
RRKSTLASRLERQGAELKAAEAEVELSARRLRAWGARVQAQGHTLQVAGLRGPVLRLREP
LGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATVFPAGLAN
VVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRGCPRAWDQEAE
GAGPELGLRVARTKALWLPMGD

Sequence length

802

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Glioblastoma	Glioblastoma	CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587		GWAS, CBGDA

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Glioblastoma	Associate	35116021
Gout	Associate	28642574
Neoplasms	Associate	35116021

ALDH16A1 (aldehyde dehydrogenase 16 family member A1)