Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	124460
Gene name Gene Name - the full gene name approved by the HGNC.	Sorting nexin 20
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SNX20
Synonyms (NCBI Gene) Gene synonyms aliases	SLIC1
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16q12.1
Summary Summary of gene provided in NCBI Entrez Gene.	SNX20 interacts with the cytoplasmic domain of PSGL1 (SELPLG; MIM 600738) and cycles PSGL1 into endosomes.[supplied by OMIM, Feb 2010]

Show/Hide all(100)

miRTarBase ID	miRNA	Experiments	Reference
MIRT718849	hsa-miR-4639-3p	HITS-CLIP	19536157
MIRT718848	hsa-miR-1207-3p	HITS-CLIP	19536157
MIRT718847	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT718846	hsa-miR-4254	HITS-CLIP	19536157
MIRT718845	hsa-miR-6787-3p	HITS-CLIP	19536157
MIRT718844	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT718843	hsa-miR-1254	HITS-CLIP	19536157
MIRT718842	hsa-miR-3116	HITS-CLIP	19536157
MIRT718841	hsa-miR-661	HITS-CLIP	19536157
MIRT718840	hsa-miR-505-5p	HITS-CLIP	19536157
MIRT718839	hsa-miR-1271-3p	HITS-CLIP	19536157
MIRT718838	hsa-miR-550a-3-5p	HITS-CLIP	19536157
MIRT718837	hsa-miR-550a-5p	HITS-CLIP	19536157
MIRT718836	hsa-miR-216a-5p	HITS-CLIP	19536157
MIRT718849	hsa-miR-4639-3p	HITS-CLIP	19536157
MIRT718848	hsa-miR-1207-3p	HITS-CLIP	19536157
MIRT718847	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT718846	hsa-miR-4254	HITS-CLIP	19536157
MIRT718845	hsa-miR-6787-3p	HITS-CLIP	19536157
MIRT718844	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT718843	hsa-miR-1254	HITS-CLIP	19536157
MIRT718842	hsa-miR-3116	HITS-CLIP	19536157
MIRT718841	hsa-miR-661	HITS-CLIP	19536157
MIRT718840	hsa-miR-505-5p	HITS-CLIP	19536157
MIRT718839	hsa-miR-1271-3p	HITS-CLIP	19536157
MIRT718838	hsa-miR-550a-3-5p	HITS-CLIP	19536157
MIRT718837	hsa-miR-550a-5p	HITS-CLIP	19536157
MIRT718836	hsa-miR-216a-5p	HITS-CLIP	19536157
MIRT1377276	hsa-miR-185	CLIP-seq
MIRT1377277	hsa-miR-4306	CLIP-seq
MIRT1377278	hsa-miR-4644	CLIP-seq
MIRT1377279	hsa-miR-4796-3p	CLIP-seq
MIRT1377280	hsa-miR-1293	CLIP-seq
MIRT1377281	hsa-miR-3144-5p	CLIP-seq
MIRT1377282	hsa-miR-3151	CLIP-seq
MIRT1377283	hsa-miR-3168	CLIP-seq
MIRT1377284	hsa-miR-3191	CLIP-seq
MIRT1377285	hsa-miR-342-5p	CLIP-seq
MIRT1377286	hsa-miR-3675-5p	CLIP-seq
MIRT1377287	hsa-miR-4265	CLIP-seq
MIRT1377288	hsa-miR-4267	CLIP-seq
MIRT1377289	hsa-miR-4289	CLIP-seq
MIRT1377290	hsa-miR-4293	CLIP-seq
MIRT1377291	hsa-miR-4296	CLIP-seq
MIRT1377292	hsa-miR-4322	CLIP-seq
MIRT1377293	hsa-miR-4447	CLIP-seq
MIRT1377294	hsa-miR-4472	CLIP-seq
MIRT1377295	hsa-miR-4483	CLIP-seq
MIRT1377296	hsa-miR-4651	CLIP-seq
MIRT1377297	hsa-miR-4652-5p	CLIP-seq
MIRT1377298	hsa-miR-4664-5p	CLIP-seq
MIRT1377299	hsa-miR-4691-3p	CLIP-seq
MIRT1377300	hsa-miR-4786-3p	CLIP-seq
MIRT1377301	hsa-miR-4797-5p	CLIP-seq
MIRT1377302	hsa-miR-491-5p	CLIP-seq
MIRT1377303	hsa-miR-608	CLIP-seq
MIRT1377304	hsa-miR-876-3p	CLIP-seq
MIRT1377305	hsa-miR-1273e	CLIP-seq
MIRT1377306	hsa-miR-1285	CLIP-seq
MIRT1377307	hsa-miR-1303	CLIP-seq
MIRT1377308	hsa-miR-3187-5p	CLIP-seq
MIRT1377309	hsa-miR-323-5p	CLIP-seq
MIRT1377310	hsa-miR-3650	CLIP-seq
MIRT1377311	hsa-miR-3689a-3p	CLIP-seq
MIRT1377312	hsa-miR-3689c	CLIP-seq
MIRT1377313	hsa-miR-3929	CLIP-seq
MIRT1377314	hsa-miR-4419b	CLIP-seq
MIRT1377315	hsa-miR-4478	CLIP-seq
MIRT1377316	hsa-miR-4677-3p	CLIP-seq
MIRT1377317	hsa-miR-4728-5p	CLIP-seq
MIRT1377318	hsa-miR-4786-5p	CLIP-seq
MIRT1377319	hsa-miR-485-5p	CLIP-seq
MIRT1377320	hsa-miR-612	CLIP-seq
MIRT1377304	hsa-miR-876-3p	CLIP-seq
MIRT1377321	hsa-miR-890	CLIP-seq
MIRT1377305	hsa-miR-1273e	CLIP-seq
MIRT1377311	hsa-miR-3689a-3p	CLIP-seq
MIRT1377312	hsa-miR-3689c	CLIP-seq
MIRT1377313	hsa-miR-3929	CLIP-seq
MIRT1377314	hsa-miR-4419b	CLIP-seq
MIRT1377315	hsa-miR-4478	CLIP-seq
MIRT1377317	hsa-miR-4728-5p	CLIP-seq
MIRT1377319	hsa-miR-485-5p	CLIP-seq
MIRT1377321	hsa-miR-890	CLIP-seq
MIRT2629540	hsa-miR-1262	CLIP-seq
MIRT2629541	hsa-miR-4252	CLIP-seq
MIRT2629542	hsa-miR-4325	CLIP-seq
MIRT2629543	hsa-miR-451b	CLIP-seq
MIRT2629544	hsa-miR-4696	CLIP-seq
MIRT2629545	hsa-miR-4701-3p	CLIP-seq
MIRT2629546	hsa-miR-4793-3p	CLIP-seq
MIRT2629547	hsa-miR-542-3p	CLIP-seq
MIRT2629548	hsa-miR-622	CLIP-seq
MIRT2629540	hsa-miR-1262	CLIP-seq
MIRT2629541	hsa-miR-4252	CLIP-seq
MIRT2629542	hsa-miR-4325	CLIP-seq
MIRT2629545	hsa-miR-4701-3p	CLIP-seq
MIRT2629546	hsa-miR-4793-3p	CLIP-seq
MIRT2629547	hsa-miR-542-3p	CLIP-seq
MIRT2629548	hsa-miR-622	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 18196517, 25416956, 31515488, 32296183, 32814053
GO:0005546	Function	Phosphatidylinositol-4,5-bisphosphate binding	ISS
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0031901	Component	Early endosome membrane	IBA
GO:0031901	Component	Early endosome membrane	IEA
GO:0031901	Component	Early endosome membrane	ISS
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	ISS
GO:0035091	Function	Phosphatidylinositol binding	IEA
GO:1901981	Function	Phosphatidylinositol phosphate binding	IBA

MIM	HGNC	e!Ensembl
613281	30390	ENSG00000167208

Protein

UniProt ID

Q7Z614

Protein name

Sorting nexin-20 (Selectin ligand-interactor cytoplasmic 1) (SLIC-1)

Protein function

May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00787	PX	103 → 187	PX domain	Domain

Sequence

MASPEHPGSPGCMGPITQCTARTQQEAPATGPDLPHPGPDGHLDTHSGLSSNSSMTTREL
QQYWQNQKCRWKHVKLLFEIASARIEERKVSKFVVYQIIVIQTGSFDNNKAVLERRYSDF
AKLQKALLKTFREEIEDVEFPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREF
LDFLTRPELREAFGCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAVPALCAVLLCHRDL
DRPAEAFAAGERALQRLQAREGHRYYAPLLDAMVRLAYALGKDFVTLQERLEESQLRRPT
PRGITLKELTVREYLH

Sequence length

316

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Crohn Disease	Crohn's disease, Crohn's disease or Leprosy (opposite effect)	N/A	N/A	GWAS
Inflammatory Bowel Disease	Inflammatory bowel disease, Inflammatory bowel disease (MTAG)	N/A	N/A	GWAS
Leprosy	Leprosy	N/A	N/A	GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Glioma	Associate	35771139
Inflammation	Associate	35771139
Neoplasms	Associate	34743576
Uveal melanoma	Associate	34743576

SNX20 (sorting nexin 20)