Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
124222
Gene name Gene Name - the full gene name approved by the HGNC.
Progestin and adipoQ receptor family member 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PAQR4
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p13.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT029666 hsa-miR-26b-5p Microarray 19088304
MIRT048738 hsa-miR-96-5p CLASH 23622248
MIRT1213368 hsa-miR-1207-5p CLIP-seq
MIRT1213369 hsa-miR-122 CLIP-seq
MIRT738866 hsa-miR-1225-5p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0016021 Component Integral component of membrane IEA
GO:0038023 Function Signaling receptor activity IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614578 26386 ENSG00000162073
Protein
UniProt ID Q8N4S7
Protein name Progestin and adipoQ receptor family member 4 (Progestin and adipoQ receptor family member IV)
Protein function Plays a role in maintaining adipose tissue function through the regulation of ceramide levels (PubMed:32291319, PubMed:38961186). Mediates the stability of ceramide synthetases, CERS2 and CERS5, and their activities (Probable). {ECO:0000269|PubM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03006 HlyIII 43 254 Haemolysin-III related Family
Tissue specificity TISSUE SPECIFICITY: Relatively widely expressed in a range of tissues. Expressed in subcutaneous white adipose tissue (PubMed:38961186). {ECO:0000269|PubMed:16044242, ECO:0000269|PubMed:38961186}.
Sequence
Sequence length 273
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 27415467
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Stimulate 36573110
Carcinogenesis Associate 36481756
Carcinoma Hepatocellular Stimulate 35240821
Carcinoma Renal Cell Associate 36481756
Neoplasms Associate 30322804, 36573110
Neoplasms Stimulate 36481756
Stomach Neoplasms Associate 30322804
Urinary Bladder Neoplasms Stimulate 36481756