PAQR4 (progestin and adipoQ receptor family member 4)

Gene

• Entrez ID: 124222
• Gene name: Progestin and adipoQ receptor family member 4
• Gene symbol: PAQR4
• Synonyms (NCBI Gene): -
• Chromosome: 16
• Chromosome location: 16p13.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT029666	hsa-miR-26b-5p	Microarray	19088304
MIRT048738	hsa-miR-96-5p	CLASH	23622248
MIRT1213368	hsa-miR-1207-5p	CLIP-seq
MIRT1213369	hsa-miR-122	CLIP-seq
MIRT738866	hsa-miR-1225-5p	CLIP-seq
MIRT1213370	hsa-miR-1234	CLIP-seq
MIRT1213371	hsa-miR-1286	CLIP-seq
MIRT1213372	hsa-miR-1910	CLIP-seq
MIRT1213373	hsa-miR-1976	CLIP-seq
MIRT1213374	hsa-miR-2467-3p	CLIP-seq
MIRT1213375	hsa-miR-3141	CLIP-seq
MIRT1213376	hsa-miR-3160-3p	CLIP-seq
MIRT1213377	hsa-miR-3166	CLIP-seq
MIRT1213378	hsa-miR-3190	CLIP-seq
MIRT1213379	hsa-miR-3194-5p	CLIP-seq
MIRT1213380	hsa-miR-3198	CLIP-seq
MIRT1213381	hsa-miR-3545-3p	CLIP-seq
MIRT1213382	hsa-miR-3678-3p	CLIP-seq
MIRT1213383	hsa-miR-370	CLIP-seq
MIRT738868	hsa-miR-4269	CLIP-seq
MIRT1213384	hsa-miR-4309	CLIP-seq
MIRT1213385	hsa-miR-432	CLIP-seq
MIRT1213386	hsa-miR-4329	CLIP-seq
MIRT1213387	hsa-miR-4330	CLIP-seq
MIRT1213388	hsa-miR-4419a	CLIP-seq
MIRT1213389	hsa-miR-4487	CLIP-seq
MIRT1213390	hsa-miR-4510	CLIP-seq
MIRT1213391	hsa-miR-451b	CLIP-seq
MIRT1213392	hsa-miR-455-3p	CLIP-seq
MIRT1213393	hsa-miR-4663	CLIP-seq
MIRT1213394	hsa-miR-4680-5p	CLIP-seq
MIRT1213395	hsa-miR-4685-5p	CLIP-seq
MIRT1213396	hsa-miR-4736	CLIP-seq
MIRT1213397	hsa-miR-4763-3p	CLIP-seq
MIRT1213398	hsa-miR-4771	CLIP-seq
MIRT738867	hsa-miR-4783-3p	CLIP-seq
MIRT1213399	hsa-miR-556-5p	CLIP-seq
MIRT1213400	hsa-miR-558	CLIP-seq
MIRT738865	hsa-miR-619	CLIP-seq
MIRT1213401	hsa-miR-671-5p	CLIP-seq
MIRT1213402	hsa-miR-7	CLIP-seq
MIRT738866	hsa-miR-1225-5p	CLIP-seq
MIRT738868	hsa-miR-4269	CLIP-seq
MIRT738867	hsa-miR-4783-3p	CLIP-seq
MIRT738865	hsa-miR-619	CLIP-seq
MIRT2061339	hsa-miR-1184	CLIP-seq
MIRT2061340	hsa-miR-1200	CLIP-seq
MIRT2061341	hsa-miR-1207-3p	CLIP-seq
MIRT1213368	hsa-miR-1207-5p	CLIP-seq
MIRT2061342	hsa-miR-1225-3p	CLIP-seq
MIRT2061343	hsa-miR-1233	CLIP-seq
MIRT2061344	hsa-miR-1252	CLIP-seq
MIRT2061345	hsa-miR-125a-5p	CLIP-seq
MIRT2061346	hsa-miR-125b	CLIP-seq
MIRT2061347	hsa-miR-1270	CLIP-seq
MIRT2061348	hsa-miR-1285	CLIP-seq
MIRT2061349	hsa-miR-1293	CLIP-seq
MIRT2061350	hsa-miR-129-3p	CLIP-seq
MIRT2061351	hsa-miR-133a	CLIP-seq
MIRT2061352	hsa-miR-133b	CLIP-seq
MIRT2061353	hsa-miR-183	CLIP-seq
MIRT1213372	hsa-miR-1910	CLIP-seq
MIRT2061354	hsa-miR-1915	CLIP-seq
MIRT1213373	hsa-miR-1976	CLIP-seq
MIRT2061355	hsa-miR-223	CLIP-seq
MIRT1213374	hsa-miR-2467-3p	CLIP-seq
MIRT2061356	hsa-miR-2467-5p	CLIP-seq
MIRT2061357	hsa-miR-28-5p	CLIP-seq
MIRT2061358	hsa-miR-2964a-5p	CLIP-seq
MIRT2061359	hsa-miR-3074-5p	CLIP-seq
MIRT2061360	hsa-miR-3139	CLIP-seq
MIRT1213375	hsa-miR-3141	CLIP-seq
MIRT1213376	hsa-miR-3160-3p	CLIP-seq
MIRT1213377	hsa-miR-3166	CLIP-seq
MIRT2061361	hsa-miR-3173-5p	CLIP-seq
MIRT2061362	hsa-miR-3177-3p	CLIP-seq
MIRT2061363	hsa-miR-3187-5p	CLIP-seq
MIRT2061364	hsa-miR-3188	CLIP-seq
MIRT1213378	hsa-miR-3190	CLIP-seq
MIRT2061365	hsa-miR-3192	CLIP-seq
MIRT1213379	hsa-miR-3194-5p	CLIP-seq
MIRT2061366	hsa-miR-3200-5p	CLIP-seq
MIRT2061367	hsa-miR-3202	CLIP-seq
MIRT2061368	hsa-miR-326	CLIP-seq
MIRT2061369	hsa-miR-330-5p	CLIP-seq
MIRT2061370	hsa-miR-339-3p	CLIP-seq
MIRT2061371	hsa-miR-339-5p	CLIP-seq
MIRT2061372	hsa-miR-3616-3p	CLIP-seq
MIRT2061373	hsa-miR-3622a-5p	CLIP-seq
MIRT2061374	hsa-miR-3659	CLIP-seq
MIRT2061375	hsa-miR-3670	CLIP-seq
MIRT1213382	hsa-miR-3678-3p	CLIP-seq
MIRT2061376	hsa-miR-3689a-3p	CLIP-seq
MIRT2061377	hsa-miR-3689c	CLIP-seq
MIRT1213383	hsa-miR-370	CLIP-seq
MIRT2061378	hsa-miR-3714	CLIP-seq
MIRT2061379	hsa-miR-378g	CLIP-seq
MIRT2061380	hsa-miR-3928	CLIP-seq
MIRT2061381	hsa-miR-3929	CLIP-seq
MIRT2061382	hsa-miR-3975	CLIP-seq
MIRT738868	hsa-miR-4269	CLIP-seq
MIRT2061383	hsa-miR-4313	CLIP-seq
MIRT2061384	hsa-miR-4319	CLIP-seq
MIRT1213385	hsa-miR-432	CLIP-seq
MIRT2061385	hsa-miR-4324	CLIP-seq
MIRT2061386	hsa-miR-4328	CLIP-seq
MIRT1213386	hsa-miR-4329	CLIP-seq
MIRT1213388	hsa-miR-4419a	CLIP-seq
MIRT2061387	hsa-miR-4419b	CLIP-seq
MIRT2061388	hsa-miR-4426	CLIP-seq
MIRT2061389	hsa-miR-4435	CLIP-seq
MIRT2061390	hsa-miR-4436b-3p	CLIP-seq
MIRT2061391	hsa-miR-4443	CLIP-seq
MIRT2061392	hsa-miR-4446-3p	CLIP-seq
MIRT2061393	hsa-miR-4453	CLIP-seq
MIRT2061394	hsa-miR-4456	CLIP-seq
MIRT2061395	hsa-miR-4474-3p	CLIP-seq
MIRT2061396	hsa-miR-4478	CLIP-seq
MIRT2061397	hsa-miR-4483	CLIP-seq
MIRT2061398	hsa-miR-4486	CLIP-seq
MIRT1213389	hsa-miR-4487	CLIP-seq
MIRT2061399	hsa-miR-4492	CLIP-seq
MIRT2061400	hsa-miR-4493	CLIP-seq
MIRT2061401	hsa-miR-4498	CLIP-seq
MIRT1213390	hsa-miR-4510	CLIP-seq
MIRT2061402	hsa-miR-4533	CLIP-seq
MIRT2061403	hsa-miR-4534	CLIP-seq
MIRT2061404	hsa-miR-4538	CLIP-seq
MIRT1213392	hsa-miR-455-3p	CLIP-seq
MIRT2061405	hsa-miR-4647	CLIP-seq
MIRT2061406	hsa-miR-4649-3p	CLIP-seq
MIRT2061407	hsa-miR-4658	CLIP-seq
MIRT2061408	hsa-miR-4662b	CLIP-seq
MIRT1213393	hsa-miR-4663	CLIP-seq
MIRT2061409	hsa-miR-4668-5p	CLIP-seq
MIRT2061410	hsa-miR-4683	CLIP-seq
MIRT1213395	hsa-miR-4685-5p	CLIP-seq
MIRT2061411	hsa-miR-4697-3p	CLIP-seq
MIRT2061412	hsa-miR-4721	CLIP-seq
MIRT2061413	hsa-miR-4726-3p	CLIP-seq
MIRT2061414	hsa-miR-4728-5p	CLIP-seq
MIRT2061415	hsa-miR-4731-5p	CLIP-seq
MIRT2061416	hsa-miR-4747-5p	CLIP-seq
MIRT2061417	hsa-miR-4761-5p	CLIP-seq
MIRT1213397	hsa-miR-4763-3p	CLIP-seq
MIRT1213398	hsa-miR-4771	CLIP-seq
MIRT2061418	hsa-miR-4772-5p	CLIP-seq
MIRT2061419	hsa-miR-4774-5p	CLIP-seq
MIRT2061420	hsa-miR-483-5p	CLIP-seq
MIRT2061421	hsa-miR-485-5p	CLIP-seq
MIRT2061422	hsa-miR-541	CLIP-seq
MIRT2061423	hsa-miR-544b	CLIP-seq
MIRT2061424	hsa-miR-548an	CLIP-seq
MIRT2061425	hsa-miR-550a	CLIP-seq
MIRT1213399	hsa-miR-556-5p	CLIP-seq
MIRT1213400	hsa-miR-558	CLIP-seq
MIRT2061426	hsa-miR-564	CLIP-seq
MIRT2061427	hsa-miR-574-5p	CLIP-seq
MIRT2061428	hsa-miR-592	CLIP-seq
MIRT2061429	hsa-miR-593	CLIP-seq
MIRT2061430	hsa-miR-597	CLIP-seq
MIRT2061431	hsa-miR-604	CLIP-seq
MIRT2061432	hsa-miR-612	CLIP-seq
MIRT2061433	hsa-miR-614	CLIP-seq
MIRT2061434	hsa-miR-615-5p	CLIP-seq
MIRT2061435	hsa-miR-620	CLIP-seq
MIRT2061436	hsa-miR-642b	CLIP-seq
MIRT2061437	hsa-miR-646	CLIP-seq
MIRT2061438	hsa-miR-647	CLIP-seq
MIRT2061439	hsa-miR-654-5p	CLIP-seq
MIRT2061440	hsa-miR-663b	CLIP-seq
MIRT2061441	hsa-miR-668	CLIP-seq
MIRT1213401	hsa-miR-671-5p	CLIP-seq
MIRT1213402	hsa-miR-7	CLIP-seq
MIRT2061442	hsa-miR-708	CLIP-seq
MIRT2061443	hsa-miR-762	CLIP-seq
MIRT2061444	hsa-miR-873	CLIP-seq
MIRT2061445	hsa-miR-940	CLIP-seq
MIRT2061347	hsa-miR-1270	CLIP-seq
MIRT2061348	hsa-miR-1285	CLIP-seq
MIRT2061349	hsa-miR-1293	CLIP-seq
MIRT1213373	hsa-miR-1976	CLIP-seq
MIRT2289883	hsa-miR-302a	CLIP-seq
MIRT2289884	hsa-miR-302b	CLIP-seq
MIRT2289885	hsa-miR-302c	CLIP-seq
MIRT2289886	hsa-miR-302d	CLIP-seq
MIRT2289887	hsa-miR-302e	CLIP-seq
MIRT2289888	hsa-miR-3160-5p	CLIP-seq
MIRT2061363	hsa-miR-3187-5p	CLIP-seq
MIRT2061365	hsa-miR-3192	CLIP-seq
MIRT2061367	hsa-miR-3202	CLIP-seq
MIRT2061368	hsa-miR-326	CLIP-seq
MIRT2061369	hsa-miR-330-5p	CLIP-seq
MIRT2061370	hsa-miR-339-3p	CLIP-seq
MIRT2061376	hsa-miR-3689a-3p	CLIP-seq
MIRT2061377	hsa-miR-3689c	CLIP-seq
MIRT2289889	hsa-miR-3691-3p	CLIP-seq
MIRT1213383	hsa-miR-370	CLIP-seq
MIRT2289890	hsa-miR-372	CLIP-seq
MIRT2289891	hsa-miR-373	CLIP-seq
MIRT2061379	hsa-miR-378g	CLIP-seq
MIRT2289892	hsa-miR-4267	CLIP-seq
MIRT1213385	hsa-miR-432	CLIP-seq
MIRT1213386	hsa-miR-4329	CLIP-seq
MIRT2061392	hsa-miR-4446-3p	CLIP-seq
MIRT2061395	hsa-miR-4474-3p	CLIP-seq
MIRT2061397	hsa-miR-4483	CLIP-seq
MIRT2061398	hsa-miR-4486	CLIP-seq
MIRT1213389	hsa-miR-4487	CLIP-seq
MIRT2061399	hsa-miR-4492	CLIP-seq
MIRT2061400	hsa-miR-4493	CLIP-seq
MIRT2061401	hsa-miR-4498	CLIP-seq
MIRT2061402	hsa-miR-4533	CLIP-seq
MIRT1213393	hsa-miR-4663	CLIP-seq
MIRT2061410	hsa-miR-4683	CLIP-seq
MIRT2061412	hsa-miR-4721	CLIP-seq
MIRT2061414	hsa-miR-4728-5p	CLIP-seq
MIRT2061415	hsa-miR-4731-5p	CLIP-seq
MIRT2061418	hsa-miR-4772-5p	CLIP-seq
MIRT2061419	hsa-miR-4774-5p	CLIP-seq
MIRT2289893	hsa-miR-512-3p	CLIP-seq
MIRT2289894	hsa-miR-520a-3p	CLIP-seq
MIRT2289895	hsa-miR-520b	CLIP-seq
MIRT2289896	hsa-miR-520c-3p	CLIP-seq
MIRT2289897	hsa-miR-520d-3p	CLIP-seq
MIRT2289898	hsa-miR-520e	CLIP-seq
MIRT2061431	hsa-miR-604	CLIP-seq
MIRT2061432	hsa-miR-612	CLIP-seq
MIRT2061435	hsa-miR-620	CLIP-seq
MIRT2061436	hsa-miR-642b	CLIP-seq
MIRT2061438	hsa-miR-647	CLIP-seq
MIRT2061443	hsa-miR-762	CLIP-seq
MIRT1213373	hsa-miR-1976	CLIP-seq
MIRT2061370	hsa-miR-339-3p	CLIP-seq
MIRT1213383	hsa-miR-370	CLIP-seq
MIRT2392119	hsa-miR-4265	CLIP-seq
MIRT2392120	hsa-miR-4296	CLIP-seq
MIRT2392121	hsa-miR-4322	CLIP-seq
MIRT1213386	hsa-miR-4329	CLIP-seq
MIRT2392122	hsa-miR-4417	CLIP-seq
MIRT1213393	hsa-miR-4663	CLIP-seq
MIRT2061421	hsa-miR-485-5p	CLIP-seq
MIRT1213379	hsa-miR-3194-5p	CLIP-seq
MIRT1213401	hsa-miR-671-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	32291319
GO:0000139	Component	Golgi membrane	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0016020	Component	Membrane	IEA
GO:0050821	Process	Protein stabilization	IDA	38961186
GO:0050821	Process	Protein stabilization	IEA
GO:0060090	Function	Molecular adaptor activity	IDA	38961186
GO:0060090	Function	Molecular adaptor activity	IEA
GO:2000303	Process	Regulation of ceramide biosynthetic process	IDA	32291319, 38961186
GO:2000303	Process	Regulation of ceramide biosynthetic process	IEA

Other IDs

• MIM: 614578
• HGNC: 26386
• e!Ensembl: ENSG00000162073

Protein

• UniProt ID: Q8N4S7
• Protein name: Progestin and adipoQ receptor family member 4 (Progestin and adipoQ receptor family member IV)
• Protein function: Plays a role in maintaining adipose tissue function through the regulation of ceramide levels (PubMed:32291319, PubMed:38961186). Mediates the stability of ceramide synthetases, CERS2 and CERS5, and their activities (Probable). {ECO:0000269|PubM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03006	HlyIII	43 → 254	Haemolysin-III related	Family

• Tissue specificity: TISSUE SPECIFICITY: Relatively widely expressed in a range of tissues. Expressed in subcutaneous white adipose tissue (PubMed:38961186). {ECO:0000269|PubMed:16044242, ECO:0000269|PubMed:38961186}.
• Sequence:

  MAFLAGPRLLDWASSPPHLQFNKFVLTGYRPASSGSGCLRSLFYLHNELGNIYTHGLALL
  GFLVLVPMTMPWGQLGKDGWLGGTHCVACLAPPAGSVLYHLFMCHQGGSAVYARLLALDM
  CGVCLVNTLGALPIIHCTLACRPWLRPAALVGYTVLSGVAGWRALTAPSTSARLRAFGWQ
  AAARLLVFGARGVGLGSGAPGSLPCYLRMDALALLGGLVNVARLPERWGPGRFDYWGNSH
  QIMHLLSVGSILQLHAGVVPDLLWAAHHACPRD

• Sequence length: 273

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Gastric cancer	Uncertain significance	rs376908274	RCV005932581

Associations from Text Mining
Disease Name	Relationship Type	References
Breast Neoplasms	Stimulate	36573110
Carcinogenesis	Associate	36481756
Carcinoma Hepatocellular	Stimulate	35240821
Carcinoma Renal Cell	Associate	36481756
Neoplasms	Associate	30322804, 36573110
Neoplasms	Stimulate	36481756
Stomach Neoplasms	Associate	30322804
Urinary Bladder Neoplasms	Stimulate	36481756