Gene Gene information from NCBI Gene database.
Entrez ID 1240
Gene name Chemerin chemokine-like receptor 1
Gene symbol CMKLR1
Synonyms (NCBI Gene)
CHEMERINRChemR23DEZERV1RVER1
Chromosome 12
Chromosome location 12q23.3
miRNA miRNA information provided by mirtarbase database.
266
miRTarBase ID miRNA Experiments Reference
MIRT710975 hsa-miR-3127-3p HITS-CLIP 19536157
MIRT710974 hsa-miR-6756-3p HITS-CLIP 19536157
MIRT710973 hsa-miR-5088-3p HITS-CLIP 19536157
MIRT710972 hsa-miR-3183 HITS-CLIP 19536157
MIRT710971 hsa-miR-4723-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
43
GO ID Ontology Definition Evidence Reference
GO:0001501 Process Skeletal system development TAS 9144535
GO:0002430 Process Complement receptor mediated signaling pathway IBA
GO:0004875 Function Complement receptor activity IBA
GO:0004930 Function G protein-coupled receptor activity IBA
GO:0004930 Function G protein-coupled receptor activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
602351 2121 ENSG00000174600
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q99788
Protein name Chemerin-like receptor 1 (Chemokine-like receptor 1) (G-protein coupled receptor ChemR23) (G-protein coupled receptor DEZ)
Protein function Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses
PDB 7YKD , 8SG1 , 8ZJG , 9L3W
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 57 316 7 transmembrane receptor (rhodopsin family) Family
Tissue specificity TISSUE SPECIFICITY: Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array o
Sequence
Sequence length 373
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Class A/1 (Rhodopsin-like receptors)