NIPA1 (NIPA magnesium transporter 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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123606 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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NIPA magnesium transporter 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NIPA1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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FSP3, SLC57A1, SPG6 |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q11.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants enc |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q7RTP0 | ||||||||||
| Protein name | Magnesium transporter NIPA1 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 1) (Spastic paraplegia 6 protein) | ||||||||||
| Protein function | Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Zn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed with highest levels in neuronal tissues. {ECO:0000269|PubMed:14508710}. | ||||||||||
| Sequence | |||||||||||
| Sequence length | 329 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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