RLN3 (relaxin 3)

Gene
Gene Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
117579
Gene name Gene Name - the full gene name approved by the HGNC.
Relaxin 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RLN3
Synonyms (NCBI Gene) Gene synonyms aliases
H3, RXN3, ZINS4, insl7
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.12
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is p
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0001664 Function G protein-coupled receptor binding IBA 21873635
GO:0005179 Function Hormone activity IEA
GO:0005515 Function Protein binding IPI 24802387
GO:0005576 Component Extracellular region TAS
GO:0007186 Process G protein-coupled receptor signaling pathway TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
606855 17135 ENSG00000171136
Protein
Gene Gene ontology Other IDs Protein Pathways
UniProt ID Q8WXF3
Protein name Relaxin-3 (Insulin-like peptide INSL7) (Insulin-like peptide 7) (Prorelaxin H3) [Cleaved into: Relaxin-3 B chain; Relaxin-3 A chain]
Protein function May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4.
PDB 2FHW , 2K1V
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00049 Insulin 32 → 142 Insulin/IGF/Relaxin family Domain
Sequence
Sequence length 142
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Protein Pathways
  KEGG   Reactome
  Neuroactive ligand-receptor interaction
Relaxin signaling pathway 		  G alpha (s) signalling events
G alpha (i) signalling events
Relaxin receptors
ADORA2B mediated anti-inflammatory cytokines production