KCTD12 (potassium channel tetramerization domain containing 12)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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115207 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Potassium channel tetramerization domain containing 12 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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KCTD12 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C13orf2, PFET1, PFETIN |
Chromosome
Chromosome number
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13 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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13q22.3 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q96CX2 | ||||||||||
Protein name | BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain) | ||||||||||
Protein function | Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitizatio | ||||||||||
PDB | 6M8S , 6QZL | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung. {ECO:0000269|PubMed:15357420}. | ||||||||||
Sequence |
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Sequence length | 325 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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