Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	114928
Gene name Gene Name - the full gene name approved by the HGNC.	G protein-coupled receptor associated sorting protein 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	GPRASP2
Synonyms (NCBI Gene) Gene synonyms aliases	DFNX7, GASP2
Disease Acronyms (UniProt) Disease acronyms from UniProt database	DFNX7
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xq22.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs). The encoded protein has been shown to be capable of interacting with several GPCRs, including the M1 muscarinic acetylcholine rece

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miRTarBase ID	miRNA	Experiments	Reference
MIRT037464	hsa-miR-744-5p	CLASH	23622248
MIRT1032146	hsa-miR-1271	CLIP-seq
MIRT1032147	hsa-miR-182	CLIP-seq
MIRT1032148	hsa-miR-3662	CLIP-seq
MIRT1032149	hsa-miR-4642	CLIP-seq
MIRT1032150	hsa-miR-4698	CLIP-seq
MIRT1032151	hsa-miR-579	CLIP-seq
MIRT1032152	hsa-miR-640	CLIP-seq
MIRT1032153	hsa-miR-96	CLIP-seq
MIRT1032154	hsa-miR-3065-5p	CLIP-seq
MIRT1032155	hsa-miR-3120-3p	CLIP-seq
MIRT1032156	hsa-miR-378	CLIP-seq
MIRT1032157	hsa-miR-378b	CLIP-seq
MIRT1032158	hsa-miR-378c	CLIP-seq
MIRT1032159	hsa-miR-378d	CLIP-seq
MIRT1032160	hsa-miR-378e	CLIP-seq
MIRT1032161	hsa-miR-378f	CLIP-seq
MIRT1032162	hsa-miR-378h	CLIP-seq
MIRT1032163	hsa-miR-378i	CLIP-seq
MIRT1032164	hsa-miR-422a	CLIP-seq
MIRT1032165	hsa-miR-451b	CLIP-seq
MIRT1032166	hsa-miR-4520a-3p	CLIP-seq
MIRT1032167	hsa-miR-4638-3p	CLIP-seq
MIRT1032168	hsa-miR-4696	CLIP-seq
MIRT2542532	hsa-miR-200b	CLIP-seq
MIRT2542533	hsa-miR-200c	CLIP-seq
MIRT1032155	hsa-miR-3120-3p	CLIP-seq
MIRT2542534	hsa-miR-374c	CLIP-seq
MIRT1032156	hsa-miR-378	CLIP-seq
MIRT1032157	hsa-miR-378b	CLIP-seq
MIRT1032158	hsa-miR-378c	CLIP-seq
MIRT1032159	hsa-miR-378d	CLIP-seq
MIRT1032160	hsa-miR-378e	CLIP-seq
MIRT1032161	hsa-miR-378f	CLIP-seq
MIRT1032162	hsa-miR-378h	CLIP-seq
MIRT1032163	hsa-miR-378i	CLIP-seq
MIRT1032164	hsa-miR-422a	CLIP-seq
MIRT2542535	hsa-miR-429	CLIP-seq
MIRT1032165	hsa-miR-451b	CLIP-seq
MIRT1032166	hsa-miR-4520a-3p	CLIP-seq
MIRT1032167	hsa-miR-4638-3p	CLIP-seq
MIRT1032168	hsa-miR-4696	CLIP-seq
MIRT2542536	hsa-miR-4724-5p	CLIP-seq
MIRT2542537	hsa-miR-570	CLIP-seq
MIRT2542538	hsa-miR-642b	CLIP-seq
MIRT2542539	hsa-miR-655	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0001540	Function	Amyloid-beta binding	IEA
GO:0001664	Function	G protein-coupled receptor binding	IDA	15086532
GO:0005515	Function	Protein binding	IPI	15383276, 21988832, 25416956, 25910212, 26871637, 28514442, 31515488, 32296183, 32814053
GO:0005634	Component	Nucleus	IDA
GO:0005737	Component	Cytoplasm	IDA
GO:0061484	Process	Hematopoietic stem cell homeostasis	IEA

MIM	HGNC	e!Ensembl
300969	25169	ENSG00000158301

Protein

UniProt ID

Q96D09

Protein name

G-protein coupled receptor-associated sorting protein 2 (GASP-2)

Protein function

May play a role in regulation of a variety of G-protein coupled receptors.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04826	Arm_2	584 → 837	Armadillo-like	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in the brain. {ECO:0000269|PubMed:15086532}.

Sequence

MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS

Sequence length

838

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Deafness	DEAFNESS, X-LINKED 7	rs267607135, rs387906219, rs387906220, rs387906221, rs387906222, rs606231120, rs267606855, rs121918370, rs137853185, rs137853186, rs137853187, rs137853188, rs587776522, rs587776523, rs200781822 View all (1019 more)	28096187
External auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome, x-linked	X-linked external auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome	rs1569491884

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Ptosis	Blepharoptosis, Ptosis	ClinVar
External Auditory Canal Atresia-Dilated Internal Auditory Canal-Facial Dysmorphism Syndrome, X-Linked	X-linked external auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome	GenCC

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Hearing Loss	Associate	28096187

GPRASP2 (G protein-coupled receptor associated sorting protein 2)