Gene Gene information from NCBI Gene database.
Entrez ID 114885
Gene name Oxysterol binding protein like 11
Gene symbol OSBPL11
Synonyms (NCBI Gene)
ORP-11ORP11OSBP12TCCCIA00292
Chromosome 3
Chromosome location 3q21.2
Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like stero
miRNA miRNA information provided by mirtarbase database.
322
miRTarBase ID miRNA Experiments Reference
MIRT019404 hsa-miR-148b-3p Microarray 17612493
MIRT025790 hsa-miR-7-5p Microarray 17612493
MIRT040400 hsa-miR-615-3p CLASH 23622248
MIRT025790 hsa-miR-7-5p Luciferase reporter assayWestern blottingqRT-PCR 35012554
MIRT1205988 hsa-miR-1185 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19615732, 20599956, 22906437, 35271311
GO:0005654 Component Nucleoplasm IDA
GO:0005768 Component Endosome IEA
GO:0005794 Component Golgi apparatus IBA
GO:0005794 Component Golgi apparatus IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606739 16397 ENSG00000144909
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BXB4
Protein name Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)
Protein function Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193). Interacts with OSBPL9
PDB 2D9X
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00169 PH 60 155 PH domain Domain
PF01237 Oxysterol_BP 372 738 Oxysterol-binding protein Family
Tissue specificity TISSUE SPECIFICITY: Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956). Present
Sequence
Sequence length 747
Interactions View interactions