OSBPL11 (oxysterol binding protein like 11)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 114885 |
| Gene name | Oxysterol binding protein like 11 |
| Gene symbol | OSBPL11 |
| Synonyms (NCBI Gene) |
ORP-11ORP11OSBP12TCCCIA00292
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| Chromosome | 3 |
| Chromosome location | 3q21.2 |
| Summary | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like stero |
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miRNA
miRNA information provided by mirtarbase database.
322
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9BXB4 | |||||||||||||||
| Protein name | Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11) | |||||||||||||||
| Protein function | Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193). Interacts with OSBPL9 | |||||||||||||||
| PDB | 2D9X | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956). Present | |||||||||||||||
| Sequence |
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| Sequence length | 747 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||