Gene Gene information from NCBI Gene database.
Entrez ID 114884
Gene name Oxysterol binding protein like 10
Gene symbol OSBPL10
Synonyms (NCBI Gene)
ORP10OSBP9
Chromosome 3
Chromosome location 3p23-p22.3
Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like stero
miRNA miRNA information provided by mirtarbase database.
797
miRTarBase ID miRNA Experiments Reference
MIRT020572 hsa-miR-155-5p Proteomics 18668040
MIRT023671 hsa-miR-1-3p Proteomics 18668040
MIRT024715 hsa-miR-215-5p Microarray 19074876
MIRT026342 hsa-miR-192-5p Microarray 19074876
MIRT027577 hsa-miR-98-5p Microarray 19088304
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
GO ID Ontology Definition Evidence Reference
GO:0001786 Function Phosphatidylserine binding IDA 23934110
GO:0005319 Function Lipid transporter activity IEA
GO:0005515 Function Protein binding IPI 19615732, 22906437
GO:0005548 Function Phospholipid transporter activity TAS
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606738 16395 ENSG00000144645
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BXB5
Protein name Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10)
Protein function Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15409 PH_8 79 170 Pleckstrin homology domain Domain
PF01237 Oxysterol_BP 402 762 Oxysterol-binding protein Family
Sequence
MERAVQGTDGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGS
VAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRG
VLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACA
KYHMEMNSKS
APSSRSRSLTLLPHGTPNSASPCSQRHLSVGAPGVVTITHHKSPAAARRAKSQYSGQLHE
VREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNLLQQSV
HQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAILPNSAEDEQTS
QPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKVVLPT
FILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYN
PIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPIS
CFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSIL
TIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWN
GTLEFTYNNGETKVIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQ
KRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWK
AH
Sequence length 764
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Acyl chain remodelling of PS