SLC22A9 (solute carrier family 22 member 9)

Gene

• Entrez ID: 114571
• Gene name: Solute carrier family 22 member 9
• Gene symbol: SLC22A9
• Synonyms (NCBI Gene): HOAT4, OAT4, OAT7, UST3H, ust3
• Chromosome: 11
• Chromosome location: 11q12.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT622258	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT622257	hsa-miR-4277	HITS-CLIP	23824327
MIRT622256	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT622255	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT622254	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT622253	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT622252	hsa-miR-6882-3p	HITS-CLIP	23824327
MIRT622251	hsa-miR-145-5p	HITS-CLIP	23824327
MIRT622250	hsa-miR-5195-3p	HITS-CLIP	23824327
MIRT622249	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT622248	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT622258	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT622257	hsa-miR-4277	HITS-CLIP	23824327
MIRT622256	hsa-miR-3925-3p	HITS-CLIP	23824327
MIRT622255	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT622254	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT622253	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT622252	hsa-miR-6882-3p	HITS-CLIP	23824327
MIRT622251	hsa-miR-145-5p	HITS-CLIP	23824327
MIRT622250	hsa-miR-5195-3p	HITS-CLIP	23824327
MIRT622249	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT622248	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT2104950	hsa-miR-1	CLIP-seq
MIRT2104951	hsa-miR-1226	CLIP-seq
MIRT2104952	hsa-miR-1297	CLIP-seq
MIRT2104953	hsa-miR-1343	CLIP-seq
MIRT2104954	hsa-miR-150	CLIP-seq
MIRT2104955	hsa-miR-18a	CLIP-seq
MIRT2104956	hsa-miR-18b	CLIP-seq
MIRT2104957	hsa-miR-1913	CLIP-seq
MIRT2104958	hsa-miR-1976	CLIP-seq
MIRT2104959	hsa-miR-206	CLIP-seq
MIRT2104960	hsa-miR-26a	CLIP-seq
MIRT2104961	hsa-miR-26b	CLIP-seq
MIRT2104962	hsa-miR-3136-3p	CLIP-seq
MIRT2104963	hsa-miR-324-3p	CLIP-seq
MIRT2104964	hsa-miR-3652	CLIP-seq
MIRT2104965	hsa-miR-3673	CLIP-seq
MIRT2104966	hsa-miR-3677-5p	CLIP-seq
MIRT2104967	hsa-miR-3692	CLIP-seq
MIRT2104968	hsa-miR-4279	CLIP-seq
MIRT2104969	hsa-miR-4430	CLIP-seq
MIRT2104970	hsa-miR-4438	CLIP-seq
MIRT2104971	hsa-miR-4465	CLIP-seq
MIRT2104972	hsa-miR-4707-3p	CLIP-seq
MIRT2104973	hsa-miR-4722-3p	CLIP-seq
MIRT2104974	hsa-miR-4731-5p	CLIP-seq
MIRT2104975	hsa-miR-4733-3p	CLIP-seq
MIRT2104976	hsa-miR-4735-3p	CLIP-seq
MIRT2104977	hsa-miR-4761-5p	CLIP-seq
MIRT2104978	hsa-miR-5095	CLIP-seq
MIRT2104979	hsa-miR-562	CLIP-seq
MIRT2104980	hsa-miR-613	CLIP-seq
MIRT2104981	hsa-miR-663b	CLIP-seq
MIRT2104950	hsa-miR-1	CLIP-seq
MIRT2104951	hsa-miR-1226	CLIP-seq
MIRT2104954	hsa-miR-150	CLIP-seq
MIRT2104955	hsa-miR-18a	CLIP-seq
MIRT2104956	hsa-miR-18b	CLIP-seq
MIRT2104957	hsa-miR-1913	CLIP-seq
MIRT2104958	hsa-miR-1976	CLIP-seq
MIRT2104959	hsa-miR-206	CLIP-seq
MIRT2104962	hsa-miR-3136-3p	CLIP-seq
MIRT2104963	hsa-miR-324-3p	CLIP-seq
MIRT2104964	hsa-miR-3652	CLIP-seq
MIRT2104965	hsa-miR-3673	CLIP-seq
MIRT2104966	hsa-miR-3677-5p	CLIP-seq
MIRT2104967	hsa-miR-3692	CLIP-seq
MIRT2104968	hsa-miR-4279	CLIP-seq
MIRT2104969	hsa-miR-4430	CLIP-seq
MIRT2104970	hsa-miR-4438	CLIP-seq
MIRT2104972	hsa-miR-4707-3p	CLIP-seq
MIRT2104973	hsa-miR-4722-3p	CLIP-seq
MIRT2104974	hsa-miR-4731-5p	CLIP-seq
MIRT2104975	hsa-miR-4733-3p	CLIP-seq
MIRT2104976	hsa-miR-4735-3p	CLIP-seq
MIRT2104977	hsa-miR-4761-5p	CLIP-seq
MIRT2104978	hsa-miR-5095	CLIP-seq
MIRT2104980	hsa-miR-613	CLIP-seq
MIRT2104981	hsa-miR-663b	CLIP-seq
MIRT2104950	hsa-miR-1	CLIP-seq
MIRT2104951	hsa-miR-1226	CLIP-seq
MIRT2104959	hsa-miR-206	CLIP-seq
MIRT2104962	hsa-miR-3136-3p	CLIP-seq
MIRT2104964	hsa-miR-3652	CLIP-seq
MIRT2104965	hsa-miR-3673	CLIP-seq
MIRT2104966	hsa-miR-3677-5p	CLIP-seq
MIRT2104969	hsa-miR-4430	CLIP-seq
MIRT2104975	hsa-miR-4733-3p	CLIP-seq
MIRT2104980	hsa-miR-613	CLIP-seq
MIRT2104981	hsa-miR-663b	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
HNF1A	Activation	20829431

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IEA
GO:0006869	Process	Lipid transport	IEA
GO:0008514	Function	Organic anion transmembrane transporter activity	IDA	17393504
GO:0009914	Process	Hormone transport	IDA	17393504
GO:0015347	Function	Sodium-independent organic anion transmembrane transporter activity	IDA	17393504
GO:0015636	Function	Short-chain fatty acid transmembrane transporter activity	IDA	17393504
GO:0015711	Process	Organic anion transport	IBA
GO:0015913	Process	Short-chain fatty acid transmembrane transport	IDA	17393504
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IDA	17393504
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IEA
GO:0043252	Process	Sodium-independent organic anion transport	IDA	17393504
GO:0055085	Process	Transmembrane transport	IEA

Other IDs

• MIM: 607579
• HGNC: 16261
• e!Ensembl: ENSG00000149742

Protein

• UniProt ID: Q8IVM8
• Protein name: Organic anion transporter 7 (OAT7) (Organic anion/short-chain fatty acid exchanger) (Solute carrier family 22 member 9)
• Protein function: Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS) (PubMed:17393504, PubMed:26239079, Pub
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07690	MFS_1	116 → 485	Major Facilitator Superfamily	Family

• Tissue specificity: TISSUE SPECIFICITY: Specifically expressed in liver (also at protein level). {ECO:0000269|PubMed:11327718, ECO:0000269|PubMed:17393504, ECO:0000269|PubMed:26239079}.
• Sequence:

  MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVS
  DNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGW
  VYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCY
  LQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCP
  SGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELR
  KAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFA
  NFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAIC
  LLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIA
  GALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKDPRE
  PKQEDPRVEVTQF

• Sequence length: 553