STK38 (serine/threonine kinase 38)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11329 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Serine/threonine kinase 38 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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STK38 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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NDR, NDR1 |
Chromosome
Chromosome number
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6 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.31 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cy |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q15208 | |||||||||||||||
Protein name | Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1) | |||||||||||||||
Protein function | Serine/threonine-protein kinase that acts as a negative regulator of MAP3K1/2 signaling (PubMed:12493777, PubMed:15197186, PubMed:17906693, PubMed:7761441). Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits | |||||||||||||||
PDB | 1PSB , 6BXI | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitously expressed with highest levels observed in peripheral blood leukocytes. {ECO:0000269|PubMed:15197186, ECO:0000269|PubMed:7761441}. | |||||||||||||||
Sequence |
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Sequence length | 465 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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