Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
113220
Gene name Gene Name - the full gene name approved by the HGNC.
Kinesin family member 12
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
KIF12
Synonyms (NCBI Gene) Gene synonyms aliases
PFIC8
Disease Acronyms (UniProt) Disease acronyms from UniProt database
PFIC8
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q32
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A simil
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT1093208 hsa-miR-377 CLIP-seq
MIRT1093209 hsa-miR-4649-3p CLIP-seq
MIRT1093210 hsa-miR-622 CLIP-seq
MIRT2024975 hsa-miR-15a CLIP-seq
MIRT2024976 hsa-miR-15b CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0003777 Function Microtubule motor activity IBA 21873635
GO:0005524 Function ATP binding IEA
GO:0005737 Component Cytoplasm IEA
GO:0005871 Component Kinesin complex IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
611278 21495 ENSG00000136883
Protein
UniProt ID Q96FN5
Protein name Kinesin-like protein KIF12
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00225 Kinesin 31 360 Kinesin motor domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in fetal liver, adult brain and pancreatic islet as well as in kidney tumors, uterus cancer and pancreatic cancer. {ECO:0000269|PubMed:15643526}.
Sequence
MEERGSPDGDLARSLEQGPEGPETPIQVVLRVRPMSAAELRRGQQSVLHCSGTRTLQGGP
EVAFRFGAVLDAARTQEDVFRACGVRRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQ
GEGVPVPPSLAGIMQRTFAWLLDRVQHLGAPVTLRASYLEIYNEQVRDLLSLGSPRPLPV
RWNKTRGFYVEQLRVVEFGSLEALMELLQTGLSRRRNSAHTLNQASSRSHALLTLYISRQ
TAQQMPSVDPGEPPVGGKLCFVDLAGSEKVAATGSRGELMLEANSINRSLLALGHCISLL
LDPQRKQSHIPFRDSKLTKLLADSLGGRGVTLMVACVSPSAQCLPETLSTLRYASRAQRV

TTRPQAPKSPVAKQPQRLETEMLQLQEENRRLQFQLDQMDCKASGLSGARVAWAQRNLYG
MLQEFMLENERLRKEKSQLQNSRDLAQNEQRILAQQVHALERRLLSACYHHQQGPGLTPP
CPCLMAPAPPCHALPPLYSCPCCHICPLCRVPLAHWACLPGEHHLPQVLDPEASGGRPPS
ARPPPWAPPCSPGSAKCPRERSHSDWTQTRVLAEMLTEEEVVPSAPPLPVRPPKTSPGLR
GGAGVPNLAQRLEALRDQIGSSLRRGRSQPPCSEGARSPGQVLPPH
Sequence length 646
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Motor proteins   COPI-dependent Golgi-to-ER retrograde traffic
Kinesins
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Coronary heart disease Coronary heart disease 23364394 ClinVar
Cholestasis cholestasis, progressive familial intrahepatic, 8 GenCC
Associations from Text Mining
Disease Name Relationship Type References
Bile Duct Diseases Associate 30250217
Breast Neoplasms Associate 21479552
Cakut Associate 36830709
Cholangitis Sclerosing Associate 30250217
Cholestasis Associate 34555379
Liver Diseases Associate 30250217, 34555379