SEC63 (SEC63 protein translocation regulator)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11231 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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SEC63 protein translocation regulator |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SEC63 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DNAJC23, ERdj2, PCLD2, PRO2507, SEC63L |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q21 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q9UGP8 | ||||||||||||||||||||
| Protein name | Translocation protein SEC63 homolog (DnaJ homolog subfamily C member 23) | ||||||||||||||||||||
| Protein function | Mediates cotranslational and post-translational transport of certain precursor polypeptides across endoplasmic reticulum (ER) (PubMed:22375059, PubMed:29719251). Proposed to play an auxiliary role in recognition of precursors with short and apol | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed, with high levels in the liver. {ECO:0000269|PubMed:15133510}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 760 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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