Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	11216
Gene name Gene Name - the full gene name approved by the HGNC.	A-kinase anchoring protein 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	AKAP10
Synonyms (NCBI Gene) Gene synonyms aliases	AKAP-10, D-AKAP-2, D-AKAP2, PRKA10
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mito

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SNP ID	Visualize variation	Clinical significance	Consequence
rs203462	T>C	Risk-factor	Coding sequence variant, genic downstream transcript variant, missense variant, non coding transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT043412	hsa-miR-331-3p	CLASH	23622248
MIRT042793	hsa-miR-339-5p	CLASH	23622248
MIRT568562	hsa-miR-129-5p	PAR-CLIP	20371350
MIRT524946	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT524945	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT568561	hsa-miR-548aw	PAR-CLIP	20371350
MIRT568560	hsa-miR-518a-5p	PAR-CLIP	20371350
MIRT568559	hsa-miR-527	PAR-CLIP	20371350
MIRT568558	hsa-miR-450b-5p	PAR-CLIP	20371350
MIRT568557	hsa-miR-507	PAR-CLIP	20371350
MIRT568556	hsa-miR-557	PAR-CLIP	20371350
MIRT568555	hsa-miR-3680-3p	PAR-CLIP	20371350
MIRT559644	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT559643	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT559642	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT559641	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT559640	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT559639	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT559638	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT559636	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT559637	hsa-miR-3671	PAR-CLIP	21572407
MIRT559635	hsa-miR-3191-5p	PAR-CLIP	21572407
MIRT559634	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT559633	hsa-miR-6505-5p	PAR-CLIP	21572407
MIRT524946	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT524945	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT441244	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT441244	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT568562	hsa-miR-129-5p	PAR-CLIP	20371350
MIRT524946	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT524945	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT568561	hsa-miR-548aw	PAR-CLIP	20371350
MIRT568560	hsa-miR-518a-5p	PAR-CLIP	20371350
MIRT568559	hsa-miR-527	PAR-CLIP	20371350
MIRT568558	hsa-miR-450b-5p	PAR-CLIP	20371350
MIRT568557	hsa-miR-507	PAR-CLIP	20371350
MIRT568556	hsa-miR-557	PAR-CLIP	20371350
MIRT568555	hsa-miR-3680-3p	PAR-CLIP	20371350
MIRT559644	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT559643	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT559642	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT559641	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT559640	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT559639	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT559638	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT559636	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT559637	hsa-miR-3671	PAR-CLIP	21572407
MIRT559635	hsa-miR-3191-5p	PAR-CLIP	21572407
MIRT559634	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT559633	hsa-miR-6505-5p	PAR-CLIP	21572407
MIRT524946	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT524945	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT775198	hsa-miR-1208	CLIP-seq
MIRT775199	hsa-miR-1255a	CLIP-seq
MIRT775200	hsa-miR-1255b	CLIP-seq
MIRT775201	hsa-miR-1297	CLIP-seq
MIRT775202	hsa-miR-137	CLIP-seq
MIRT775203	hsa-miR-224	CLIP-seq
MIRT775204	hsa-miR-26a	CLIP-seq
MIRT775205	hsa-miR-26b	CLIP-seq
MIRT775206	hsa-miR-30a	CLIP-seq
MIRT775207	hsa-miR-30b	CLIP-seq
MIRT775208	hsa-miR-30c	CLIP-seq
MIRT775209	hsa-miR-30d	CLIP-seq
MIRT775210	hsa-miR-30e	CLIP-seq
MIRT775211	hsa-miR-3129-3p	CLIP-seq
MIRT775212	hsa-miR-3148	CLIP-seq
MIRT775213	hsa-miR-3149	CLIP-seq
MIRT775214	hsa-miR-3162-5p	CLIP-seq
MIRT775215	hsa-miR-3168	CLIP-seq
MIRT775216	hsa-miR-3173-3p	CLIP-seq
MIRT775217	hsa-miR-325	CLIP-seq
MIRT775218	hsa-miR-3607-5p	CLIP-seq
MIRT775219	hsa-miR-383	CLIP-seq
MIRT775220	hsa-miR-3920	CLIP-seq
MIRT775221	hsa-miR-3978	CLIP-seq
MIRT775222	hsa-miR-4275	CLIP-seq
MIRT775223	hsa-miR-4277	CLIP-seq
MIRT775224	hsa-miR-4420	CLIP-seq
MIRT775225	hsa-miR-4424	CLIP-seq
MIRT775226	hsa-miR-4465	CLIP-seq
MIRT775227	hsa-miR-4473	CLIP-seq
MIRT775228	hsa-miR-4495	CLIP-seq
MIRT775229	hsa-miR-4533	CLIP-seq
MIRT775230	hsa-miR-4633-5p	CLIP-seq
MIRT775231	hsa-miR-4659a-5p	CLIP-seq
MIRT775232	hsa-miR-4659b-5p	CLIP-seq
MIRT775233	hsa-miR-4711-5p	CLIP-seq
MIRT775234	hsa-miR-4728-3p	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT775236	hsa-miR-4775	CLIP-seq
MIRT775237	hsa-miR-4776-3p	CLIP-seq
MIRT775238	hsa-miR-512-3p	CLIP-seq
MIRT775239	hsa-miR-520f	CLIP-seq
MIRT775240	hsa-miR-532-5p	CLIP-seq
MIRT775241	hsa-miR-542-3p	CLIP-seq
MIRT775242	hsa-miR-552	CLIP-seq
MIRT775243	hsa-miR-574-5p	CLIP-seq
MIRT775244	hsa-miR-590-3p	CLIP-seq
MIRT775245	hsa-miR-628-3p	CLIP-seq
MIRT775246	hsa-miR-648	CLIP-seq
MIRT775247	hsa-miR-892a	CLIP-seq
MIRT775203	hsa-miR-224	CLIP-seq
MIRT775216	hsa-miR-3173-3p	CLIP-seq
MIRT775224	hsa-miR-4420	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT775203	hsa-miR-224	CLIP-seq
MIRT775216	hsa-miR-3173-3p	CLIP-seq
MIRT775224	hsa-miR-4420	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT775199	hsa-miR-1255a	CLIP-seq
MIRT775200	hsa-miR-1255b	CLIP-seq
MIRT775201	hsa-miR-1297	CLIP-seq
MIRT1928742	hsa-miR-217	CLIP-seq
MIRT775203	hsa-miR-224	CLIP-seq
MIRT775204	hsa-miR-26a	CLIP-seq
MIRT775205	hsa-miR-26b	CLIP-seq
MIRT1928743	hsa-miR-3159	CLIP-seq
MIRT775214	hsa-miR-3162-5p	CLIP-seq
MIRT1928744	hsa-miR-3165	CLIP-seq
MIRT775215	hsa-miR-3168	CLIP-seq
MIRT775216	hsa-miR-3173-3p	CLIP-seq
MIRT1928745	hsa-miR-3190	CLIP-seq
MIRT775220	hsa-miR-3920	CLIP-seq
MIRT775223	hsa-miR-4277	CLIP-seq
MIRT775224	hsa-miR-4420	CLIP-seq
MIRT775225	hsa-miR-4424	CLIP-seq
MIRT775226	hsa-miR-4465	CLIP-seq
MIRT1928746	hsa-miR-4686	CLIP-seq
MIRT775233	hsa-miR-4711-5p	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT775243	hsa-miR-574-5p	CLIP-seq
MIRT1928747	hsa-miR-584	CLIP-seq
MIRT775246	hsa-miR-648	CLIP-seq
MIRT775198	hsa-miR-1208	CLIP-seq
MIRT775199	hsa-miR-1255a	CLIP-seq
MIRT775200	hsa-miR-1255b	CLIP-seq
MIRT775202	hsa-miR-137	CLIP-seq
MIRT2169539	hsa-miR-208a	CLIP-seq
MIRT2169540	hsa-miR-208b	CLIP-seq
MIRT2169541	hsa-miR-2115	CLIP-seq
MIRT775203	hsa-miR-224	CLIP-seq
MIRT775214	hsa-miR-3162-5p	CLIP-seq
MIRT775216	hsa-miR-3173-3p	CLIP-seq
MIRT2169542	hsa-miR-3658	CLIP-seq
MIRT775220	hsa-miR-3920	CLIP-seq
MIRT775222	hsa-miR-4275	CLIP-seq
MIRT775224	hsa-miR-4420	CLIP-seq
MIRT775225	hsa-miR-4424	CLIP-seq
MIRT2169543	hsa-miR-4432	CLIP-seq
MIRT1928746	hsa-miR-4686	CLIP-seq
MIRT775233	hsa-miR-4711-5p	CLIP-seq
MIRT775234	hsa-miR-4728-3p	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT2169544	hsa-miR-499-5p	CLIP-seq
MIRT2169545	hsa-miR-516a-3p	CLIP-seq
MIRT775247	hsa-miR-892a	CLIP-seq
MIRT775203	hsa-miR-224	CLIP-seq
MIRT775216	hsa-miR-3173-3p	CLIP-seq
MIRT775220	hsa-miR-3920	CLIP-seq
MIRT775224	hsa-miR-4420	CLIP-seq
MIRT775234	hsa-miR-4728-3p	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT2472108	hsa-miR-10a	CLIP-seq
MIRT2472109	hsa-miR-10b	CLIP-seq
MIRT775198	hsa-miR-1208	CLIP-seq
MIRT2472110	hsa-miR-1228	CLIP-seq
MIRT2472111	hsa-miR-1229	CLIP-seq
MIRT2472112	hsa-miR-1237	CLIP-seq
MIRT2472113	hsa-miR-1254	CLIP-seq
MIRT775199	hsa-miR-1255a	CLIP-seq
MIRT775200	hsa-miR-1255b	CLIP-seq
MIRT2472114	hsa-miR-1266	CLIP-seq
MIRT2472115	hsa-miR-127-5p	CLIP-seq
MIRT2472116	hsa-miR-130a	CLIP-seq
MIRT2472117	hsa-miR-130b	CLIP-seq
MIRT2472118	hsa-miR-149	CLIP-seq
MIRT2472119	hsa-miR-155	CLIP-seq
MIRT2472120	hsa-miR-185	CLIP-seq
MIRT2472121	hsa-miR-1909	CLIP-seq
MIRT1928742	hsa-miR-217	CLIP-seq
MIRT2472122	hsa-miR-22	CLIP-seq
MIRT2472123	hsa-miR-223	CLIP-seq
MIRT2472124	hsa-miR-29a	CLIP-seq
MIRT2472125	hsa-miR-29b	CLIP-seq
MIRT2472126	hsa-miR-29c	CLIP-seq
MIRT2472127	hsa-miR-301a	CLIP-seq
MIRT2472128	hsa-miR-301b	CLIP-seq
MIRT2472129	hsa-miR-3116	CLIP-seq
MIRT2472130	hsa-miR-3123	CLIP-seq
MIRT2472131	hsa-miR-3151	CLIP-seq
MIRT775214	hsa-miR-3162-5p	CLIP-seq
MIRT2472132	hsa-miR-3175	CLIP-seq
MIRT2472133	hsa-miR-3182	CLIP-seq
MIRT2472134	hsa-miR-3202	CLIP-seq
MIRT2472135	hsa-miR-320a	CLIP-seq
MIRT2472136	hsa-miR-320b	CLIP-seq
MIRT2472137	hsa-miR-320c	CLIP-seq
MIRT2472138	hsa-miR-320d	CLIP-seq
MIRT2472139	hsa-miR-330-3p	CLIP-seq
MIRT775218	hsa-miR-3607-5p	CLIP-seq
MIRT2472140	hsa-miR-3615	CLIP-seq
MIRT2472141	hsa-miR-3620	CLIP-seq
MIRT2472142	hsa-miR-3622a-3p	CLIP-seq
MIRT2472143	hsa-miR-3622b-3p	CLIP-seq
MIRT2472144	hsa-miR-365	CLIP-seq
MIRT2472145	hsa-miR-3662	CLIP-seq
MIRT2472146	hsa-miR-3664-3p	CLIP-seq
MIRT2472147	hsa-miR-3666	CLIP-seq
MIRT2472148	hsa-miR-3667-3p	CLIP-seq
MIRT775220	hsa-miR-3920	CLIP-seq
MIRT2472149	hsa-miR-4252	CLIP-seq
MIRT775222	hsa-miR-4275	CLIP-seq
MIRT2472150	hsa-miR-4283	CLIP-seq
MIRT2472151	hsa-miR-4295	CLIP-seq
MIRT2472152	hsa-miR-4306	CLIP-seq
MIRT2472153	hsa-miR-4328	CLIP-seq
MIRT775225	hsa-miR-4424	CLIP-seq
MIRT2472154	hsa-miR-4429	CLIP-seq
MIRT2472155	hsa-miR-4433	CLIP-seq
MIRT2472156	hsa-miR-4459	CLIP-seq
MIRT2472157	hsa-miR-4489	CLIP-seq
MIRT2472158	hsa-miR-4518	CLIP-seq
MIRT2472159	hsa-miR-4524	CLIP-seq
MIRT775229	hsa-miR-4533	CLIP-seq
MIRT2472160	hsa-miR-454	CLIP-seq
MIRT775230	hsa-miR-4633-5p	CLIP-seq
MIRT2472161	hsa-miR-4644	CLIP-seq
MIRT2472162	hsa-miR-4652-3p	CLIP-seq
MIRT2472163	hsa-miR-4671-3p	CLIP-seq
MIRT2472164	hsa-miR-4690-5p	CLIP-seq
MIRT2472165	hsa-miR-4697-3p	CLIP-seq
MIRT775233	hsa-miR-4711-5p	CLIP-seq
MIRT775234	hsa-miR-4728-3p	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT2472166	hsa-miR-4764-3p	CLIP-seq
MIRT2472167	hsa-miR-4768-3p	CLIP-seq
MIRT2472168	hsa-miR-4790-3p	CLIP-seq
MIRT775240	hsa-miR-532-5p	CLIP-seq
MIRT775242	hsa-miR-552	CLIP-seq
MIRT2472169	hsa-miR-570	CLIP-seq
MIRT2472170	hsa-miR-572	CLIP-seq
MIRT775243	hsa-miR-574-5p	CLIP-seq
MIRT2472171	hsa-miR-618	CLIP-seq
MIRT2472172	hsa-miR-621	CLIP-seq
MIRT775246	hsa-miR-648	CLIP-seq
MIRT2472173	hsa-miR-661	CLIP-seq
MIRT2472174	hsa-miR-760	CLIP-seq
MIRT2472175	hsa-miR-765	CLIP-seq
MIRT2472176	hsa-miR-888	CLIP-seq
MIRT775247	hsa-miR-892a	CLIP-seq
MIRT2472108	hsa-miR-10a	CLIP-seq
MIRT2472109	hsa-miR-10b	CLIP-seq
MIRT775198	hsa-miR-1208	CLIP-seq
MIRT2472110	hsa-miR-1228	CLIP-seq
MIRT2472111	hsa-miR-1229	CLIP-seq
MIRT2472112	hsa-miR-1237	CLIP-seq
MIRT2472113	hsa-miR-1254	CLIP-seq
MIRT775199	hsa-miR-1255a	CLIP-seq
MIRT775200	hsa-miR-1255b	CLIP-seq
MIRT2472114	hsa-miR-1266	CLIP-seq
MIRT2472115	hsa-miR-127-5p	CLIP-seq
MIRT775201	hsa-miR-1297	CLIP-seq
MIRT2472116	hsa-miR-130a	CLIP-seq
MIRT2472117	hsa-miR-130b	CLIP-seq
MIRT2472118	hsa-miR-149	CLIP-seq
MIRT2472119	hsa-miR-155	CLIP-seq
MIRT2472120	hsa-miR-185	CLIP-seq
MIRT2472121	hsa-miR-1909	CLIP-seq
MIRT1928742	hsa-miR-217	CLIP-seq
MIRT2472122	hsa-miR-22	CLIP-seq
MIRT2472123	hsa-miR-223	CLIP-seq
MIRT775204	hsa-miR-26a	CLIP-seq
MIRT775205	hsa-miR-26b	CLIP-seq
MIRT2472124	hsa-miR-29a	CLIP-seq
MIRT2472125	hsa-miR-29b	CLIP-seq
MIRT2472126	hsa-miR-29c	CLIP-seq
MIRT2472127	hsa-miR-301a	CLIP-seq
MIRT2472128	hsa-miR-301b	CLIP-seq
MIRT2472129	hsa-miR-3116	CLIP-seq
MIRT2472130	hsa-miR-3123	CLIP-seq
MIRT775214	hsa-miR-3162-5p	CLIP-seq
MIRT2472132	hsa-miR-3175	CLIP-seq
MIRT2472133	hsa-miR-3182	CLIP-seq
MIRT2472135	hsa-miR-320a	CLIP-seq
MIRT2472136	hsa-miR-320b	CLIP-seq
MIRT2472137	hsa-miR-320c	CLIP-seq
MIRT2472138	hsa-miR-320d	CLIP-seq
MIRT2472139	hsa-miR-330-3p	CLIP-seq
MIRT775218	hsa-miR-3607-5p	CLIP-seq
MIRT2472140	hsa-miR-3615	CLIP-seq
MIRT2472141	hsa-miR-3620	CLIP-seq
MIRT2472144	hsa-miR-365	CLIP-seq
MIRT2472145	hsa-miR-3662	CLIP-seq
MIRT2472146	hsa-miR-3664-3p	CLIP-seq
MIRT2472147	hsa-miR-3666	CLIP-seq
MIRT2472148	hsa-miR-3667-3p	CLIP-seq
MIRT775220	hsa-miR-3920	CLIP-seq
MIRT2472149	hsa-miR-4252	CLIP-seq
MIRT775222	hsa-miR-4275	CLIP-seq
MIRT2472151	hsa-miR-4295	CLIP-seq
MIRT2472152	hsa-miR-4306	CLIP-seq
MIRT2472153	hsa-miR-4328	CLIP-seq
MIRT775225	hsa-miR-4424	CLIP-seq
MIRT2472154	hsa-miR-4429	CLIP-seq
MIRT2472155	hsa-miR-4433	CLIP-seq
MIRT2472156	hsa-miR-4459	CLIP-seq
MIRT775226	hsa-miR-4465	CLIP-seq
MIRT2472158	hsa-miR-4518	CLIP-seq
MIRT2472159	hsa-miR-4524	CLIP-seq
MIRT2472160	hsa-miR-454	CLIP-seq
MIRT775230	hsa-miR-4633-5p	CLIP-seq
MIRT2472161	hsa-miR-4644	CLIP-seq
MIRT2472162	hsa-miR-4652-3p	CLIP-seq
MIRT2472163	hsa-miR-4671-3p	CLIP-seq
MIRT2472164	hsa-miR-4690-5p	CLIP-seq
MIRT2472165	hsa-miR-4697-3p	CLIP-seq
MIRT775233	hsa-miR-4711-5p	CLIP-seq
MIRT775234	hsa-miR-4728-3p	CLIP-seq
MIRT775235	hsa-miR-4738-3p	CLIP-seq
MIRT2472166	hsa-miR-4764-3p	CLIP-seq
MIRT2472167	hsa-miR-4768-3p	CLIP-seq
MIRT2472168	hsa-miR-4790-3p	CLIP-seq
MIRT775240	hsa-miR-532-5p	CLIP-seq
MIRT775242	hsa-miR-552	CLIP-seq
MIRT2472170	hsa-miR-572	CLIP-seq
MIRT775243	hsa-miR-574-5p	CLIP-seq
MIRT2472171	hsa-miR-618	CLIP-seq
MIRT2472172	hsa-miR-621	CLIP-seq
MIRT775246	hsa-miR-648	CLIP-seq
MIRT2472173	hsa-miR-661	CLIP-seq
MIRT2472174	hsa-miR-760	CLIP-seq
MIRT2472175	hsa-miR-765	CLIP-seq
MIRT2472176	hsa-miR-888	CLIP-seq
MIRT775247	hsa-miR-892a	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	20159461
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0005886	Component	Plasma membrane	IDA
GO:0007165	Process	Signal transduction	TAS	9326583
GO:0007596	Process	Blood coagulation	TAS
GO:0008104	Process	Protein localization	IBA	21873635
GO:0032991	Component	Protein-containing complex	IDA	25097019
GO:0051018	Function	Protein kinase A binding	IPI	25097019

MIM	HGNC	e!Ensembl
604694	368	ENSG00000108599

Protein

UniProt ID

O43572

Protein name

A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)

Protein function

Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not

PDB

3IM4 , 3TMH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00615	RGS	261 → 368	Regulator of G protein signaling domain	Domain
PF00615	RGS	379 → 504	Regulator of G protein signaling domain	Domain

Sequence

MRGAGPSPRQSPRTLRPDPGPAMSFFRRKVKGKEQEKTSDVKSIKASISVHSPQKSTKNH
ALLEAAGPSHVAINAISANMDSFSSSRTATLKKQPSHMEAAHFGDLGRSCLDYQTQETKS
SLSKTLEQVLHDTIVLPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQS
SLAEPVSPSKKHETTASFLTDSLDKRLEDSGSAQLFMTHSEGIDLNNRTNSTQNHLLLSQ
ECDSAHSLRLEMARAGTHQVSMETQESSSTLTVASRNSPASPLKELSGKLMKSIEQDAVN
TFTKYISPDAAKPIPITEAMRNDIIARICGEDGQVDPNCFVLAQSIVFSAMEQEHFSEFL
RSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLA
AKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPNCFTTPL
RQAWTTMEKVFLPGFLSSNLYYKYLNDLIHSVRGDEFLGGNVSLTAPGSVGPPDESHPGS
SDSSASQSSVKKASIKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRE
SEPEPDVRKSKGSMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDIMQQAQYDQPLEKST
KL

Sequence length

662

Interactions

View interactions

	Reactome
			Factors involved in megakaryocyte development and platelet production

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Conduction disorder of the heart	Conduction disorder of the heart	rs1572627115

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.		GWAS, CBGDA

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinogenesis	Associate	23468363
Colorectal Neoplasms	Associate	23468363
Hypertension	Associate	22817328
Lymphatic Metastasis	Associate	23468363
Neoplasms	Associate	23468363, 32233832

AKAP10 (A-kinase anchoring protein 10)