Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	112
Gene name	Adenylate cyclase 6
Gene symbol	ADCY6
Synonyms (NCBI Gene)	AC6LCCS8
Chromosome	12
Chromosome location	12q13.12
Summary	This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001991	hsa-miR-96-5p	Luciferase reporter assay	17597072
MIRT001992	hsa-miR-182-5p	Luciferase reporter assayqRT-PCR	20656788
MIRT016723	hsa-miR-335-5p	Microarray	18185580
MIRT022147	hsa-miR-124-3p	Microarray	18668037
MIRT001991	hsa-miR-96-5p	Sequencing	20371350
MIRT660903	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT660901	hsa-miR-3183	HITS-CLIP	23824327
MIRT660902	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT660900	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT660899	hsa-miR-4287	HITS-CLIP	23824327
MIRT660898	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT660897	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT660896	hsa-miR-5089-3p	HITS-CLIP	23824327
MIRT660895	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT660903	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT660901	hsa-miR-3183	HITS-CLIP	23824327
MIRT660902	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT660900	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT660899	hsa-miR-4287	HITS-CLIP	23824327
MIRT660898	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT660897	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT660896	hsa-miR-5089-3p	HITS-CLIP	23824327
MIRT660895	hsa-miR-6885-3p	HITS-CLIP	23824327
MIRT768036	hsa-miR-101	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT768040	hsa-miR-128	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT768042	hsa-miR-1285	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT768044	hsa-miR-1914	CLIP-seq
MIRT768045	hsa-miR-1915	CLIP-seq
MIRT768046	hsa-miR-19a	CLIP-seq
MIRT768047	hsa-miR-19b	CLIP-seq
MIRT768048	hsa-miR-27a	CLIP-seq
MIRT768049	hsa-miR-27b	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768051	hsa-miR-3156-3p	CLIP-seq
MIRT768052	hsa-miR-3162-3p	CLIP-seq
MIRT768053	hsa-miR-3187-5p	CLIP-seq
MIRT768054	hsa-miR-3202	CLIP-seq
MIRT768055	hsa-miR-345	CLIP-seq
MIRT768056	hsa-miR-3945	CLIP-seq
MIRT768057	hsa-miR-4253	CLIP-seq
MIRT768058	hsa-miR-4301	CLIP-seq
MIRT768059	hsa-miR-4316	CLIP-seq
MIRT768060	hsa-miR-4668-5p	CLIP-seq
MIRT768061	hsa-miR-4684-5p	CLIP-seq
MIRT768062	hsa-miR-4726-3p	CLIP-seq
MIRT768063	hsa-miR-4747-5p	CLIP-seq
MIRT768064	hsa-miR-486-3p	CLIP-seq
MIRT768065	hsa-miR-490-3p	CLIP-seq
MIRT768066	hsa-miR-5096	CLIP-seq
MIRT768067	hsa-miR-513a-5p	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT768069	hsa-miR-583	CLIP-seq
MIRT768070	hsa-miR-612	CLIP-seq
MIRT768071	hsa-miR-759	CLIP-seq
MIRT768036	hsa-miR-101	CLIP-seq
MIRT768072	hsa-miR-1197	CLIP-seq
MIRT768073	hsa-miR-1264	CLIP-seq
MIRT768040	hsa-miR-128	CLIP-seq
MIRT768042	hsa-miR-1285	CLIP-seq
MIRT768074	hsa-miR-140-5p	CLIP-seq
MIRT768075	hsa-miR-1909	CLIP-seq
MIRT768045	hsa-miR-1915	CLIP-seq
MIRT768076	hsa-miR-197	CLIP-seq
MIRT768077	hsa-miR-2110	CLIP-seq
MIRT768048	hsa-miR-27a	CLIP-seq
MIRT768049	hsa-miR-27b	CLIP-seq
MIRT768078	hsa-miR-3117-5p	CLIP-seq
MIRT768079	hsa-miR-3126-3p	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768080	hsa-miR-3153	CLIP-seq
MIRT768052	hsa-miR-3162-3p	CLIP-seq
MIRT768081	hsa-miR-3173-3p	CLIP-seq
MIRT768053	hsa-miR-3187-5p	CLIP-seq
MIRT768082	hsa-miR-3199	CLIP-seq
MIRT768054	hsa-miR-3202	CLIP-seq
MIRT768083	hsa-miR-323-3p	CLIP-seq
MIRT768084	hsa-miR-331-3p	CLIP-seq
MIRT768085	hsa-miR-361-3p	CLIP-seq
MIRT768086	hsa-miR-3679-3p	CLIP-seq
MIRT768087	hsa-miR-3921	CLIP-seq
MIRT768088	hsa-miR-3922-5p	CLIP-seq
MIRT768089	hsa-miR-3936	CLIP-seq
MIRT768090	hsa-miR-3938	CLIP-seq
MIRT768056	hsa-miR-3945	CLIP-seq
MIRT768091	hsa-miR-409-5p	CLIP-seq
MIRT768057	hsa-miR-4253	CLIP-seq
MIRT768092	hsa-miR-4271	CLIP-seq
MIRT768093	hsa-miR-4286	CLIP-seq
MIRT768094	hsa-miR-4303	CLIP-seq
MIRT768059	hsa-miR-4316	CLIP-seq
MIRT768095	hsa-miR-4436a	CLIP-seq
MIRT768096	hsa-miR-4438	CLIP-seq
MIRT768097	hsa-miR-4446-5p	CLIP-seq
MIRT768098	hsa-miR-4457	CLIP-seq
MIRT768099	hsa-miR-4475	CLIP-seq
MIRT768100	hsa-miR-4476	CLIP-seq
MIRT768101	hsa-miR-4496	CLIP-seq
MIRT768102	hsa-miR-4515	CLIP-seq
MIRT768103	hsa-miR-4653-5p	CLIP-seq
MIRT768104	hsa-miR-4667-3p	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT768061	hsa-miR-4684-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT768107	hsa-miR-4725-3p	CLIP-seq
MIRT768062	hsa-miR-4726-3p	CLIP-seq
MIRT768108	hsa-miR-4786-3p	CLIP-seq
MIRT768109	hsa-miR-4802-3p	CLIP-seq
MIRT768065	hsa-miR-490-3p	CLIP-seq
MIRT768110	hsa-miR-501-3p	CLIP-seq
MIRT768111	hsa-miR-502-3p	CLIP-seq
MIRT768066	hsa-miR-5096	CLIP-seq
MIRT768067	hsa-miR-513a-5p	CLIP-seq
MIRT768112	hsa-miR-513b	CLIP-seq
MIRT768113	hsa-miR-518d-5p	CLIP-seq
MIRT768114	hsa-miR-519b-5p	CLIP-seq
MIRT768115	hsa-miR-519c-5p	CLIP-seq
MIRT768116	hsa-miR-520c-5p	CLIP-seq
MIRT768117	hsa-miR-526a	CLIP-seq
MIRT768118	hsa-miR-570	CLIP-seq
MIRT768070	hsa-miR-612	CLIP-seq
MIRT768119	hsa-miR-637	CLIP-seq
MIRT768120	hsa-miR-671-5p	CLIP-seq
MIRT768121	hsa-miR-875-3p	CLIP-seq
MIRT1926531	hsa-miR-1205	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT1926532	hsa-miR-125a-3p	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT1926534	hsa-miR-136	CLIP-seq
MIRT1926535	hsa-miR-146b-3p	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT1926537	hsa-miR-204	CLIP-seq
MIRT1926538	hsa-miR-211	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT1926541	hsa-miR-3130-5p	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT1926543	hsa-miR-3154	CLIP-seq
MIRT1926544	hsa-miR-3173-5p	CLIP-seq
MIRT1926545	hsa-miR-3180-5p	CLIP-seq
MIRT1926546	hsa-miR-320e	CLIP-seq
MIRT768055	hsa-miR-345	CLIP-seq
MIRT1926547	hsa-miR-3616-3p	CLIP-seq
MIRT1926548	hsa-miR-3665	CLIP-seq
MIRT1926549	hsa-miR-3688-3p	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT1926552	hsa-miR-4257	CLIP-seq
MIRT1926553	hsa-miR-4261	CLIP-seq
MIRT1926554	hsa-miR-4267	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT1926558	hsa-miR-4436b-3p	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT1926561	hsa-miR-4482	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT1926565	hsa-miR-4689	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT1926569	hsa-miR-4721	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT768109	hsa-miR-4802-3p	CLIP-seq
MIRT1926571	hsa-miR-494	CLIP-seq
MIRT1926572	hsa-miR-515-5p	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT1926574	hsa-miR-543	CLIP-seq
MIRT1926575	hsa-miR-657	CLIP-seq
MIRT1926576	hsa-miR-874	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq
MIRT768036	hsa-miR-101	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT2167516	hsa-miR-1245	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT768040	hsa-miR-128	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT2167517	hsa-miR-1286	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT2167518	hsa-miR-135a	CLIP-seq
MIRT2167519	hsa-miR-135b	CLIP-seq
MIRT2167520	hsa-miR-185	CLIP-seq
MIRT2167521	hsa-miR-1913	CLIP-seq
MIRT768076	hsa-miR-197	CLIP-seq
MIRT1926537	hsa-miR-204	CLIP-seq
MIRT1926538	hsa-miR-211	CLIP-seq
MIRT768077	hsa-miR-2110	CLIP-seq
MIRT768048	hsa-miR-27a	CLIP-seq
MIRT768049	hsa-miR-27b	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT2167522	hsa-miR-3064-5p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT2167524	hsa-miR-3126-5p	CLIP-seq
MIRT2167525	hsa-miR-3127-3p	CLIP-seq
MIRT2167526	hsa-miR-3128	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT2167527	hsa-miR-3144-5p	CLIP-seq
MIRT2167528	hsa-miR-3150b-3p	CLIP-seq
MIRT768080	hsa-miR-3153	CLIP-seq
MIRT2167529	hsa-miR-3155	CLIP-seq
MIRT2167530	hsa-miR-3155b	CLIP-seq
MIRT2167531	hsa-miR-3160-3p	CLIP-seq
MIRT2167532	hsa-miR-3191	CLIP-seq
MIRT2167533	hsa-miR-3201	CLIP-seq
MIRT1926546	hsa-miR-320e	CLIP-seq
MIRT2167534	hsa-miR-324-3p	CLIP-seq
MIRT2167535	hsa-miR-342-5p	CLIP-seq
MIRT2167536	hsa-miR-3609	CLIP-seq
MIRT768085	hsa-miR-361-3p	CLIP-seq
MIRT1926547	hsa-miR-3616-3p	CLIP-seq
MIRT2167537	hsa-miR-3652	CLIP-seq
MIRT2167538	hsa-miR-371b-3p	CLIP-seq
MIRT2167539	hsa-miR-376c	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT768087	hsa-miR-3921	CLIP-seq
MIRT768057	hsa-miR-4253	CLIP-seq
MIRT2167540	hsa-miR-4254	CLIP-seq
MIRT1926552	hsa-miR-4257	CLIP-seq
MIRT2167541	hsa-miR-4266	CLIP-seq
MIRT1926554	hsa-miR-4267	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT768092	hsa-miR-4271	CLIP-seq
MIRT2167542	hsa-miR-4283	CLIP-seq
MIRT2167543	hsa-miR-4290	CLIP-seq
MIRT2167544	hsa-miR-4292	CLIP-seq
MIRT768094	hsa-miR-4303	CLIP-seq
MIRT2167545	hsa-miR-4306	CLIP-seq
MIRT2167546	hsa-miR-4308	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT768059	hsa-miR-4316	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT2167547	hsa-miR-4323	CLIP-seq
MIRT2167548	hsa-miR-4430	CLIP-seq
MIRT1926558	hsa-miR-4436b-3p	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT768098	hsa-miR-4457	CLIP-seq
MIRT2167549	hsa-miR-4489	CLIP-seq
MIRT2167550	hsa-miR-4505	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT2167551	hsa-miR-4643	CLIP-seq
MIRT2167552	hsa-miR-4644	CLIP-seq
MIRT2167553	hsa-miR-4651	CLIP-seq
MIRT2167554	hsa-miR-4652-5p	CLIP-seq
MIRT768103	hsa-miR-4653-5p	CLIP-seq
MIRT2167555	hsa-miR-4664-5p	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT1926565	hsa-miR-4689	CLIP-seq
MIRT2167556	hsa-miR-4695-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT2167557	hsa-miR-4722-5p	CLIP-seq
MIRT768107	hsa-miR-4725-3p	CLIP-seq
MIRT2167558	hsa-miR-4731-5p	CLIP-seq
MIRT2167559	hsa-miR-4779	CLIP-seq
MIRT2167560	hsa-miR-4784	CLIP-seq
MIRT2167561	hsa-miR-4791	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT768109	hsa-miR-4802-3p	CLIP-seq
MIRT2167562	hsa-miR-484	CLIP-seq
MIRT768065	hsa-miR-490-3p	CLIP-seq
MIRT768066	hsa-miR-5096	CLIP-seq
MIRT768067	hsa-miR-513a-5p	CLIP-seq
MIRT2167563	hsa-miR-520g	CLIP-seq
MIRT2167564	hsa-miR-520h	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT2167565	hsa-miR-548ah	CLIP-seq
MIRT2167566	hsa-miR-608	CLIP-seq
MIRT2167567	hsa-miR-670	CLIP-seq
MIRT2167568	hsa-miR-873	CLIP-seq
MIRT768098	hsa-miR-4457	CLIP-seq
MIRT2167557	hsa-miR-4722-5p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT2441918	hsa-miR-4725-5p	CLIP-seq
MIRT2441919	hsa-miR-504	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq
MIRT2443237	hsa-miR-1321	CLIP-seq
MIRT2443238	hsa-miR-4699-5p	CLIP-seq
MIRT2443239	hsa-miR-4739	CLIP-seq
MIRT2443240	hsa-miR-4756-5p	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT2470100	hsa-miR-1231	CLIP-seq
MIRT2470101	hsa-miR-1236	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT768073	hsa-miR-1264	CLIP-seq
MIRT2470102	hsa-miR-1270	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT2470103	hsa-miR-1299	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT2167518	hsa-miR-135a	CLIP-seq
MIRT2167519	hsa-miR-135b	CLIP-seq
MIRT2470104	hsa-miR-150	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT2167520	hsa-miR-185	CLIP-seq
MIRT2470105	hsa-miR-188-3p	CLIP-seq
MIRT2470106	hsa-miR-188-5p	CLIP-seq
MIRT2470107	hsa-miR-224	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT2470108	hsa-miR-3120-5p	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT2167526	hsa-miR-3128	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT2470109	hsa-miR-3144-3p	CLIP-seq
MIRT2167527	hsa-miR-3144-5p	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768051	hsa-miR-3156-3p	CLIP-seq
MIRT768052	hsa-miR-3162-3p	CLIP-seq
MIRT2470110	hsa-miR-3162-5p	CLIP-seq
MIRT2167532	hsa-miR-3191	CLIP-seq
MIRT2167533	hsa-miR-3201	CLIP-seq
MIRT768084	hsa-miR-331-3p	CLIP-seq
MIRT2470111	hsa-miR-337-3p	CLIP-seq
MIRT2470112	hsa-miR-3614-5p	CLIP-seq
MIRT2167537	hsa-miR-3652	CLIP-seq
MIRT2470113	hsa-miR-3661	CLIP-seq
MIRT2470114	hsa-miR-3667-3p	CLIP-seq
MIRT2470115	hsa-miR-3684	CLIP-seq
MIRT2167539	hsa-miR-376c	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT2470116	hsa-miR-3929	CLIP-seq
MIRT2470117	hsa-miR-3941	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT2167543	hsa-miR-4290	CLIP-seq
MIRT768058	hsa-miR-4301	CLIP-seq
MIRT2167545	hsa-miR-4306	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT2470118	hsa-miR-4419b	CLIP-seq
MIRT2167548	hsa-miR-4430	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT2470119	hsa-miR-4474-5p	CLIP-seq
MIRT2470120	hsa-miR-4478	CLIP-seq
MIRT2167550	hsa-miR-4505	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT2470121	hsa-miR-4531	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT2167551	hsa-miR-4643	CLIP-seq
MIRT2167552	hsa-miR-4644	CLIP-seq
MIRT2470122	hsa-miR-4652-3p	CLIP-seq
MIRT2167554	hsa-miR-4652-5p	CLIP-seq
MIRT2470123	hsa-miR-466	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT2470124	hsa-miR-4672	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT2443238	hsa-miR-4699-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT2470125	hsa-miR-4714-5p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT2441918	hsa-miR-4725-5p	CLIP-seq
MIRT2470126	hsa-miR-4731-3p	CLIP-seq
MIRT2167558	hsa-miR-4731-5p	CLIP-seq
MIRT2167561	hsa-miR-4791	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT2470127	hsa-miR-4801	CLIP-seq
MIRT768110	hsa-miR-501-3p	CLIP-seq
MIRT768111	hsa-miR-502-3p	CLIP-seq
MIRT2441919	hsa-miR-504	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT768118	hsa-miR-570	CLIP-seq
MIRT2470128	hsa-miR-602	CLIP-seq
MIRT2470129	hsa-miR-619	CLIP-seq
MIRT2470130	hsa-miR-620	CLIP-seq
MIRT2470131	hsa-miR-631	CLIP-seq
MIRT2470132	hsa-miR-7	CLIP-seq
MIRT768121	hsa-miR-875-3p	CLIP-seq
MIRT2470133	hsa-miR-935	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq
MIRT768037	hsa-miR-1224-3p	CLIP-seq
MIRT2470101	hsa-miR-1236	CLIP-seq
MIRT768038	hsa-miR-1260	CLIP-seq
MIRT768039	hsa-miR-1260b	CLIP-seq
MIRT1926533	hsa-miR-1271	CLIP-seq
MIRT768041	hsa-miR-1280	CLIP-seq
MIRT768043	hsa-miR-1324	CLIP-seq
MIRT2167518	hsa-miR-135a	CLIP-seq
MIRT2167519	hsa-miR-135b	CLIP-seq
MIRT1926536	hsa-miR-182	CLIP-seq
MIRT2470105	hsa-miR-188-3p	CLIP-seq
MIRT2470106	hsa-miR-188-5p	CLIP-seq
MIRT2674533	hsa-miR-214	CLIP-seq
MIRT1926539	hsa-miR-3064-3p	CLIP-seq
MIRT2167523	hsa-miR-31	CLIP-seq
MIRT2674534	hsa-miR-3120-3p	CLIP-seq
MIRT1926540	hsa-miR-3125	CLIP-seq
MIRT2167526	hsa-miR-3128	CLIP-seq
MIRT1926542	hsa-miR-3138	CLIP-seq
MIRT2167527	hsa-miR-3144-5p	CLIP-seq
MIRT768050	hsa-miR-3148	CLIP-seq
MIRT768051	hsa-miR-3156-3p	CLIP-seq
MIRT2674535	hsa-miR-3166	CLIP-seq
MIRT2167532	hsa-miR-3191	CLIP-seq
MIRT2167533	hsa-miR-3201	CLIP-seq
MIRT2470111	hsa-miR-337-3p	CLIP-seq
MIRT2674536	hsa-miR-3619-5p	CLIP-seq
MIRT2167537	hsa-miR-3652	CLIP-seq
MIRT2470113	hsa-miR-3661	CLIP-seq
MIRT2470114	hsa-miR-3667-3p	CLIP-seq
MIRT2470115	hsa-miR-3684	CLIP-seq
MIRT2167539	hsa-miR-376c	CLIP-seq
MIRT1926550	hsa-miR-3911	CLIP-seq
MIRT1926551	hsa-miR-3916	CLIP-seq
MIRT2470116	hsa-miR-3929	CLIP-seq
MIRT1926555	hsa-miR-4270	CLIP-seq
MIRT2167543	hsa-miR-4290	CLIP-seq
MIRT2674537	hsa-miR-4291	CLIP-seq
MIRT768058	hsa-miR-4301	CLIP-seq
MIRT1926556	hsa-miR-4313	CLIP-seq
MIRT1926557	hsa-miR-4318	CLIP-seq
MIRT2470118	hsa-miR-4419b	CLIP-seq
MIRT2167548	hsa-miR-4430	CLIP-seq
MIRT1926559	hsa-miR-4441	CLIP-seq
MIRT1926560	hsa-miR-4455	CLIP-seq
MIRT2470119	hsa-miR-4474-5p	CLIP-seq
MIRT2470120	hsa-miR-4478	CLIP-seq
MIRT2167550	hsa-miR-4505	CLIP-seq
MIRT2674538	hsa-miR-451b	CLIP-seq
MIRT1926562	hsa-miR-4520a-3p	CLIP-seq
MIRT1926563	hsa-miR-4536	CLIP-seq
MIRT2167551	hsa-miR-4643	CLIP-seq
MIRT2167554	hsa-miR-4652-5p	CLIP-seq
MIRT768105	hsa-miR-4667-5p	CLIP-seq
MIRT1926564	hsa-miR-4685-5p	CLIP-seq
MIRT768106	hsa-miR-4700-5p	CLIP-seq
MIRT1926566	hsa-miR-4708-5p	CLIP-seq
MIRT1926567	hsa-miR-4713-3p	CLIP-seq
MIRT2470125	hsa-miR-4714-5p	CLIP-seq
MIRT1926568	hsa-miR-4717-3p	CLIP-seq
MIRT2441918	hsa-miR-4725-5p	CLIP-seq
MIRT2167558	hsa-miR-4731-5p	CLIP-seq
MIRT2167561	hsa-miR-4791	CLIP-seq
MIRT1926570	hsa-miR-4800-5p	CLIP-seq
MIRT768110	hsa-miR-501-3p	CLIP-seq
MIRT768111	hsa-miR-502-3p	CLIP-seq
MIRT2441919	hsa-miR-504	CLIP-seq
MIRT768068	hsa-miR-532-3p	CLIP-seq
MIRT1926573	hsa-miR-542-5p	CLIP-seq
MIRT768118	hsa-miR-570	CLIP-seq
MIRT2470129	hsa-miR-619	CLIP-seq
MIRT2470131	hsa-miR-631	CLIP-seq
MIRT2674539	hsa-miR-761	CLIP-seq
MIRT768121	hsa-miR-875-3p	CLIP-seq
MIRT2674540	hsa-miR-922	CLIP-seq
MIRT1926577	hsa-miR-96	CLIP-seq

Show/Hide all (40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003091	Process	Renal water homeostasis	ISS
GO:0004016	Function	Adenylate cyclase activity	IBA
GO:0004016	Function	Adenylate cyclase activity	IDA	17916776, 18403039, 23842570
GO:0004016	Function	Adenylate cyclase activity	IEA
GO:0005080	Function	Protein kinase C binding	IDA	17081159
GO:0005515	Function	Protein binding	IPI	17081159
GO:0005524	Function	ATP binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0005929	Component	Cilium	IEA
GO:0006171	Process	CAMP biosynthetic process	IBA
GO:0006171	Process	CAMP biosynthetic process	IDA	17916776, 18403039
GO:0006171	Process	CAMP biosynthetic process	IEA
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	17110384, 17916776
GO:0007189	Process	Adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISS
GO:0007191	Process	Adenylate cyclase-activating dopamine receptor signaling pathway	IDA	18403039
GO:0007192	Process	Adenylate cyclase-activating serotonin receptor signaling pathway	IDA	17110384
GO:0007193	Process	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISS
GO:0007198	Process	Adenylate cyclase-inhibiting serotonin receptor signaling pathway	ISS
GO:0009190	Process	Cyclic nucleotide biosynthetic process	IEA
GO:0010977	Process	Negative regulation of neuron projection development	ISS
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016829	Function	Lyase activity	IEA
GO:0016849	Function	Phosphorus-oxygen lyase activity	IEA
GO:0019901	Function	Protein kinase binding	ISS
GO:0032420	Component	Stereocilium	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0035811	Process	Negative regulation of urine volume	ISS
GO:0042995	Component	Cell projection	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0071380	Process	Cellular response to prostaglandin E stimulus	IDA	18403039
GO:0071870	Process	Cellular response to catecholamine stimulus	IDA	18403039
GO:0097746	Process	Blood vessel diameter maintenance	IMP	17916776
GO:1904117	Process	Cellular response to vasopressin	ISS
GO:1904322	Process	Cellular response to forskolin	IDA	17916776

MIM	HGNC	e!Ensembl
600294	237	ENSG00000174233

O43306

Protein name

Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)

Protein function

Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17110384, PubMed:17916776). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth musc

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16214	AC_N	11 → 368	Adenylyl cyclase N-terminal extracellular and transmembrane region	Family
PF00211	Guanylate_cyc	370 → 553	Adenylate and Guanylate cyclase catalytic domain	Domain
PF06327	DUF1053	580 → 669	Domain of Unknown Function (DUF1053)	Family
PF00211	Guanylate_cyc	970 → 1164	Adenylate and Guanylate cyclase catalytic domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in peripheral blood mononuclear leukocytes (at protein level) (PubMed:17916776). Detected in thyroid (PubMed:10978539). {ECO:0000269|PubMed:10978539}.

Sequence

MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGP
PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGRSCWR
RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAY
VALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLW
CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN
VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT
KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC
LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV
HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA
YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR
QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKK
YSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSC
GSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRSCAARMLNLT
PADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLA
MIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV
ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF
LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS
EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN
FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG
YQLECRGVVKVKGKGEMTTYFLNGGPSS

Sequence length

1168

Interactions

View interactions

	KEGG		Reactome
	Purine metabolism Metabolic pathways Endocrine resistance Rap1 signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Chemokine signaling pathway Phospholipase D signaling pathway Hormone signaling Oocyte meiosis Longevity regulating pathway Longevity regulating pathway - multiple species Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Apelin signaling pathway Gap junction Platelet activation Circadian entrainment Thermogenesis Retrograde endocannabinoid signaling Glutamatergic synapse Cholinergic synapse GABAergic synapse Taste transduction Inflammatory mediator regulation of TRP channels Insulin secretion GnRH signaling pathway Ovarian steroidogenesis Progesterone-mediated oocyte maturation Estrogen signaling pathway Melanogenesis Thyroid hormone synthesis Oxytocin signaling pathway Regulation of lipolysis in adipocytes Renin secretion Aldosterone synthesis and secretion Relaxin signaling pathway Cortisol synthesis and secretion Parathyroid hormone synthesis, secretion and action Cushing syndrome Growth hormone synthesis, secretion and action Endocrine and other factor-regulated calcium reabsorption Vasopressin-regulated water reabsorption Salivary secretion Gastric acid secretion Pancreatic secretion Bile secretion Morphine addiction Human cytomegalovirus infection Human T-cell leukemia virus 1 infection Pathways in cancer Chemical carcinogenesis - receptor activation Dilated cardiomyopathy		Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Adrenaline,noradrenaline inhibits insulin secretion G alpha (s) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Lethal congenital contracture syndrome 8	Pathogenic	rs786204798, rs1941705738, rs1941551290	RCV000169693 RCV001290106 RCV001290107

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs78519542	RCV005924412
ADCY6-related disorder	Benign; Likely benign	rs3730308, rs3730064, rs3730068, rs374675749, rs1015828855, rs200640184, rs778527060, rs148650932, rs143958339, rs747782381, rs1242330299, rs938420123, rs541746900, rs3730071, rs77913913, rs547924399, rs755937305, rs201423806 View all (3 more)	RCV003975907 RCV003975948 RCV004757472 RCV003964674 RCV003893648 RCV003906788 RCV003964519 RCV003919400 RCV003931552 RCV003941520 RCV003958999 RCV003954576 RCV003964700 RCV003976575 RCV003928589 RCV003933107 RCV003953358 RCV003906091
Cholangiocarcinoma	Benign	rs3730070	RCV005916536
Familial cancer of breast	Benign; Likely benign	rs3730070, rs375113808	RCV005916533 RCV005902978
Lung cancer	Benign; Uncertain significance	rs78519542, rs369149680	RCV005924414 RCV005932211
Malignant lymphoma, large B-cell, diffuse	Benign	rs3730070	RCV005916534
Malignant tumor of urinary bladder	Benign; Uncertain significance	rs145846390, rs778436011	RCV005907511 RCV005912212
Melanoma	Likely benign	rs375113808	RCV005902979
Ovarian serous cystadenocarcinoma	Benign	rs78519542	RCV005924413
Uterine carcinosarcoma	Benign	rs3730070	RCV005916535
Uterine corpus endometrial carcinoma	Likely benign	rs375113808	RCV005902980

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Anemia Sickle Cell	Associate	18324973
Anxiety	Associate	28969474
Arrhythmias Cardiac	Associate	27437887
Arthrogryposis	Associate	33820833
Autistic Disorder	Associate	32108986
Bone Diseases Developmental	Associate	33820833
Inflammation	Associate	28880852
Leukemia Biphenotypic Acute	Associate	34257610
Metabolic Diseases	Associate	30926763
Polycystic Kidney Autosomal Dominant	Associate	22952279
Polycystic Ovary Syndrome	Associate	33622336

ADCY6 (adenylate cyclase 6)