SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 11198 |
| Gene name | SPT16 homolog, facilitates chromatin remodeling subunit |
| Gene symbol | SUPT16H |
| Synonyms (NCBI Gene) |
CDC68FACTP140NEDDFACSPT16SPT16/CDC68
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| Chromosome | 14 |
| Chromosome location | 14q11.2 |
| Summary | Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may fa |
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miRNA
miRNA information provided by mirtarbase database.
635
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y5B9 | |||||||||||||||||||||||||
| Protein name | FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) | |||||||||||||||||||||||||
| Protein function | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During tran | |||||||||||||||||||||||||
| PDB | 4Z2M , 4Z2N , 5E5B , 5UMT , 5UMU , 5XM2 , 6UPK , 6UPL , 8I17 , 8YJF , 8YJM , 9EH2 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10792464}. | |||||||||||||||||||||||||
| Sequence | ||||||||||||||||||||||||||
| Sequence length | 1047 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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