SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11198 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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SPT16 homolog, facilitates chromatin remodeling subunit |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SUPT16H |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CDC68, FACTP140, NEDDFAC, SPT16, SPT16/CDC68 |
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Chromosome
Chromosome number
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14 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q11.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may fa |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q9Y5B9 | |||||||||||||||||||||||||
| Protein name | FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) | |||||||||||||||||||||||||
| Protein function | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During tran | |||||||||||||||||||||||||
| PDB | 4Z2M , 4Z2N , 5E5B , 5UMT , 5UMU , 5XM2 , 6UPK , 6UPL , 8I17 , 8YJF , 8YJM , 9EH2 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10792464}. | |||||||||||||||||||||||||
| Sequence | ||||||||||||||||||||||||||
| Sequence length | 1047 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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