Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	11170
Gene name	Family with sequence similarity 107 member A
Gene symbol	FAM107A
Synonyms (NCBI Gene)	DRR1TU3A
Chromosome	3
Chromosome location	3p14.3-p14.2

216

Show/Hide all (216)

miRTarBase ID	miRNA	Experiments	Reference
MIRT710276	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT710275	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT710274	hsa-miR-6752-3p	HITS-CLIP	19536157
MIRT710273	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT710272	hsa-miR-1913	HITS-CLIP	19536157
MIRT710271	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT710270	hsa-miR-18a-3p	HITS-CLIP	19536157
MIRT710269	hsa-miR-7976	HITS-CLIP	19536157
MIRT710268	hsa-miR-3173-5p	HITS-CLIP	19536157
MIRT710267	hsa-miR-6799-3p	HITS-CLIP	19536157
MIRT710266	hsa-miR-146b-3p	HITS-CLIP	19536157
MIRT710265	hsa-miR-938	HITS-CLIP	19536157
MIRT710264	hsa-miR-6886-3p	HITS-CLIP	19536157
MIRT710263	hsa-miR-346	HITS-CLIP	19536157
MIRT710262	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT710261	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT710260	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT710259	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT710258	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT710276	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT710275	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT710274	hsa-miR-6752-3p	HITS-CLIP	19536157
MIRT710273	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT710272	hsa-miR-1913	HITS-CLIP	19536157
MIRT710271	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT710270	hsa-miR-18a-3p	HITS-CLIP	19536157
MIRT710269	hsa-miR-7976	HITS-CLIP	19536157
MIRT710268	hsa-miR-3173-5p	HITS-CLIP	19536157
MIRT710267	hsa-miR-6799-3p	HITS-CLIP	19536157
MIRT710266	hsa-miR-146b-3p	HITS-CLIP	19536157
MIRT710265	hsa-miR-938	HITS-CLIP	19536157
MIRT710264	hsa-miR-6886-3p	HITS-CLIP	19536157
MIRT710263	hsa-miR-346	HITS-CLIP	19536157
MIRT710262	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT710261	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT710260	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT710259	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT710258	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT710276	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT710275	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT710274	hsa-miR-6752-3p	HITS-CLIP	19536157
MIRT710273	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT710272	hsa-miR-1913	HITS-CLIP	19536157
MIRT710271	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT710270	hsa-miR-18a-3p	HITS-CLIP	19536157
MIRT710269	hsa-miR-7976	HITS-CLIP	19536157
MIRT710268	hsa-miR-3173-5p	HITS-CLIP	19536157
MIRT710267	hsa-miR-6799-3p	HITS-CLIP	19536157
MIRT710266	hsa-miR-146b-3p	HITS-CLIP	19536157
MIRT710265	hsa-miR-938	HITS-CLIP	19536157
MIRT710264	hsa-miR-6886-3p	HITS-CLIP	19536157
MIRT710263	hsa-miR-346	HITS-CLIP	19536157
MIRT710262	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT710261	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT710260	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT710259	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT710258	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT626002	hsa-miR-4282	HITS-CLIP	23824327
MIRT663270	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616583	hsa-miR-634	HITS-CLIP	23824327
MIRT616581	hsa-miR-1226-3p	HITS-CLIP	23824327
MIRT616580	hsa-miR-4530	HITS-CLIP	23824327
MIRT616579	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT626002	hsa-miR-4282	HITS-CLIP	23824327
MIRT616583	hsa-miR-634	HITS-CLIP	23824327
MIRT616582	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT616581	hsa-miR-1226-3p	HITS-CLIP	23824327
MIRT616580	hsa-miR-4530	HITS-CLIP	23824327
MIRT616579	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT663270	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT663270	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT663270	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT663270	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT626002	hsa-miR-4282	HITS-CLIP	27418678
MIRT626002	hsa-miR-4282	HITS-CLIP	27418678
MIRT626002	hsa-miR-4282	HITS-CLIP	27418678
MIRT710276	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT710275	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT710274	hsa-miR-6752-3p	HITS-CLIP	19536157
MIRT710273	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT710272	hsa-miR-1913	HITS-CLIP	19536157
MIRT710271	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT710270	hsa-miR-18a-3p	HITS-CLIP	19536157
MIRT710269	hsa-miR-7976	HITS-CLIP	19536157
MIRT710268	hsa-miR-3173-5p	HITS-CLIP	19536157
MIRT710267	hsa-miR-6799-3p	HITS-CLIP	19536157
MIRT710266	hsa-miR-146b-3p	HITS-CLIP	19536157
MIRT710265	hsa-miR-938	HITS-CLIP	19536157
MIRT710264	hsa-miR-6886-3p	HITS-CLIP	19536157
MIRT710263	hsa-miR-346	HITS-CLIP	19536157
MIRT710262	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT710261	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT710260	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT710259	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT710258	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT710276	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT710275	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT710274	hsa-miR-6752-3p	HITS-CLIP	19536157
MIRT710273	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT710272	hsa-miR-1913	HITS-CLIP	19536157
MIRT710271	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT710270	hsa-miR-18a-3p	HITS-CLIP	19536157
MIRT710269	hsa-miR-7976	HITS-CLIP	19536157
MIRT710268	hsa-miR-3173-5p	HITS-CLIP	19536157
MIRT710267	hsa-miR-6799-3p	HITS-CLIP	19536157
MIRT710266	hsa-miR-146b-3p	HITS-CLIP	19536157
MIRT710265	hsa-miR-938	HITS-CLIP	19536157
MIRT710264	hsa-miR-6886-3p	HITS-CLIP	19536157
MIRT710263	hsa-miR-346	HITS-CLIP	19536157
MIRT710262	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT710261	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT710260	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT710259	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT710258	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT710276	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT710275	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT710274	hsa-miR-6752-3p	HITS-CLIP	19536157
MIRT710273	hsa-miR-3667-3p	HITS-CLIP	19536157
MIRT710272	hsa-miR-1913	HITS-CLIP	19536157
MIRT710271	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT710270	hsa-miR-18a-3p	HITS-CLIP	19536157
MIRT710269	hsa-miR-7976	HITS-CLIP	19536157
MIRT710268	hsa-miR-3173-5p	HITS-CLIP	19536157
MIRT710267	hsa-miR-6799-3p	HITS-CLIP	19536157
MIRT710266	hsa-miR-146b-3p	HITS-CLIP	19536157
MIRT710265	hsa-miR-938	HITS-CLIP	19536157
MIRT710264	hsa-miR-6886-3p	HITS-CLIP	19536157
MIRT710263	hsa-miR-346	HITS-CLIP	19536157
MIRT710262	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT710261	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT710260	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT710259	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT710258	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT626002	hsa-miR-4282	HITS-CLIP	23824327
MIRT663270	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616583	hsa-miR-634	HITS-CLIP	23824327
MIRT616581	hsa-miR-1226-3p	HITS-CLIP	23824327
MIRT616580	hsa-miR-4530	HITS-CLIP	23824327
MIRT616579	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT626002	hsa-miR-4282	HITS-CLIP	23824327
MIRT616583	hsa-miR-634	HITS-CLIP	23824327
MIRT616582	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT616581	hsa-miR-1226-3p	HITS-CLIP	23824327
MIRT616580	hsa-miR-4530	HITS-CLIP	23824327
MIRT616579	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT976692	hsa-miR-1262	CLIP-seq
MIRT976693	hsa-miR-1827	CLIP-seq
MIRT976694	hsa-miR-3127-5p	CLIP-seq
MIRT976695	hsa-miR-3167	CLIP-seq
MIRT976696	hsa-miR-4420	CLIP-seq
MIRT976697	hsa-miR-4452	CLIP-seq
MIRT976698	hsa-miR-4476	CLIP-seq
MIRT976699	hsa-miR-4506	CLIP-seq
MIRT976700	hsa-miR-4650-5p	CLIP-seq
MIRT976701	hsa-miR-4653-3p	CLIP-seq
MIRT976702	hsa-miR-4668-5p	CLIP-seq
MIRT976703	hsa-miR-4701-3p	CLIP-seq
MIRT976704	hsa-miR-4715-5p	CLIP-seq
MIRT976705	hsa-miR-4786-3p	CLIP-seq
MIRT976706	hsa-miR-571	CLIP-seq
MIRT976707	hsa-miR-629	CLIP-seq
MIRT976708	hsa-miR-651	CLIP-seq
MIRT976709	hsa-miR-671-5p	CLIP-seq
MIRT976710	hsa-miR-876-5p	CLIP-seq
MIRT976711	hsa-miR-1252	CLIP-seq
MIRT976692	hsa-miR-1262	CLIP-seq
MIRT976712	hsa-miR-3202	CLIP-seq
MIRT976696	hsa-miR-4420	CLIP-seq
MIRT976697	hsa-miR-4452	CLIP-seq
MIRT976699	hsa-miR-4506	CLIP-seq
MIRT976713	hsa-miR-4533	CLIP-seq
MIRT976701	hsa-miR-4653-3p	CLIP-seq
MIRT976703	hsa-miR-4701-3p	CLIP-seq
MIRT976706	hsa-miR-571	CLIP-seq
MIRT976714	hsa-miR-636	CLIP-seq
MIRT1548475	hsa-miR-432	CLIP-seq
MIRT1921778	hsa-miR-1226	CLIP-seq
MIRT1921779	hsa-miR-1228	CLIP-seq
MIRT1921778	hsa-miR-1226	CLIP-seq
MIRT1921779	hsa-miR-1228	CLIP-seq
MIRT1989451	hsa-miR-1236	CLIP-seq
MIRT1989452	hsa-miR-23a	CLIP-seq
MIRT1989453	hsa-miR-23b	CLIP-seq
MIRT1989454	hsa-miR-23c	CLIP-seq
MIRT1989455	hsa-miR-326	CLIP-seq
MIRT1989456	hsa-miR-330-5p	CLIP-seq
MIRT1989457	hsa-miR-342-5p	CLIP-seq
MIRT1989458	hsa-miR-412	CLIP-seq
MIRT1989459	hsa-miR-4539	CLIP-seq
MIRT1989460	hsa-miR-4651	CLIP-seq
MIRT1989461	hsa-miR-4664-5p	CLIP-seq
MIRT1989462	hsa-miR-4667-5p	CLIP-seq
MIRT1989463	hsa-miR-4700-5p	CLIP-seq
MIRT1989464	hsa-miR-4717-3p	CLIP-seq
MIRT1989465	hsa-miR-4753-3p	CLIP-seq
MIRT1989466	hsa-miR-608	CLIP-seq
MIRT1989467	hsa-miR-617	CLIP-seq
MIRT1989468	hsa-miR-637	CLIP-seq
MIRT1989469	hsa-miR-642b	CLIP-seq
MIRT1989470	hsa-miR-654-3p	CLIP-seq
MIRT1989471	hsa-miR-942	CLIP-seq
MIRT976692	hsa-miR-1262	CLIP-seq
MIRT2223796	hsa-miR-2964a-3p	CLIP-seq
MIRT976696	hsa-miR-4420	CLIP-seq
MIRT976697	hsa-miR-4452	CLIP-seq
MIRT976699	hsa-miR-4506	CLIP-seq
MIRT976701	hsa-miR-4653-3p	CLIP-seq
MIRT976703	hsa-miR-4701-3p	CLIP-seq
MIRT976706	hsa-miR-571	CLIP-seq
MIRT2387668	hsa-miR-3074-3p	CLIP-seq
MIRT2387669	hsa-miR-4690-3p	CLIP-seq
MIRT2680466	hsa-miR-329	CLIP-seq
MIRT2680467	hsa-miR-362-3p	CLIP-seq
MIRT2680468	hsa-miR-3941	CLIP-seq
MIRT2680469	hsa-miR-4789-5p	CLIP-seq
MIRT2680470	hsa-miR-603	CLIP-seq

Show/Hide all (43)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001558	Process	Regulation of cell growth	IDA	10564580
GO:0001725	Component	Stress fiber	IBA
GO:0001725	Component	Stress fiber	IDA	20543869
GO:0001725	Component	Stress fiber	IEA
GO:0003779	Function	Actin binding	IEA
GO:0005515	Function	Protein binding	IPI	20543869, 25416956, 28604741, 32296183
GO:0005634	Component	Nucleus	IDA	10564580, 20543869, 28604741
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	28604741
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005925	Component	Focal adhesion	IDA	20543869
GO:0005925	Component	Focal adhesion	IEA
GO:0015629	Component	Actin cytoskeleton	IDA	28604741
GO:0015629	Component	Actin cytoskeleton	ISS
GO:0016020	Component	Membrane	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0030041	Process	Actin filament polymerization	IBA
GO:0030041	Process	Actin filament polymerization	ISS
GO:0030335	Process	Positive regulation of cell migration	IMP	20543869
GO:0031398	Process	Positive regulation of protein ubiquitination	IMP	28604741
GO:0031647	Process	Regulation of protein stability	IMP	28604741
GO:0031669	Process	Cellular response to nutrient levels	ISS
GO:0032587	Component	Ruffle membrane	IDA	20543869
GO:0032587	Component	Ruffle membrane	IEA
GO:0032956	Process	Regulation of actin cytoskeleton organization	IBA
GO:0032956	Process	Regulation of actin cytoskeleton organization	IMP	20543869
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IBA
GO:0043005	Component	Neuron projection	ISS
GO:0045202	Component	Synapse	IBA
GO:0045202	Component	Synapse	IEA
GO:0045202	Component	Synapse	ISS
GO:0050890	Process	Cognition	ISS
GO:0051017	Process	Actin filament bundle assembly	IBA
GO:0051017	Process	Actin filament bundle assembly	ISS
GO:0051895	Process	Negative regulation of focal adhesion assembly	IMP	20543869
GO:0070161	Component	Anchoring junction	IEA
GO:0070507	Process	Regulation of microtubule cytoskeleton organization	IMP	20543869
GO:0071385	Process	Cellular response to glucocorticoid stimulus	ISS
GO:1900272	Process	Negative regulation of long-term synaptic potentiation	ISS
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IMP	28604741

MIM	HGNC	e!Ensembl
608295	30827	ENSG00000168309

O95990

Protein name

Actin-associated protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A)

Protein function

Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06625	DUF1151	23 → 133	Protein of unknown function (DUF1151)	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed (PubMed:10564580). Expressed in neurons (PubMed:20543869). Expressed in malignant glial tumors (PubMed:20543869). Expression is reduced or absent in a number of cancer cell lines (PubMed:10564580). {ECO:0000269|PubMed:

Sequence

MYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRELLMNHRRGLG
VDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDH
APEFIKVRENLRRIATLTSEEREL

Sequence length

144

Interactions

View interactions

FAM107A (family with sequence similarity 107 member A)