GTF2A1L (general transcription factor IIA subunit 1 like)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
11036
Gene name Gene Name - the full gene name approved by the HGNC.
General transcription factor IIA subunit 1 like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GTF2A1L
Synonyms (NCBI Gene) Gene synonyms aliases
ALF
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p16.3
Summary Summary of gene provided in NCBI Entrez Gene.
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(8)
miRTarBase ID miRNA Experiments Reference
MIRT1549413 hsa-miR-4719 CLIP-seq
MIRT1549414 hsa-miR-513b CLIP-seq
MIRT1549413 hsa-miR-4719 CLIP-seq
MIRT1549414 hsa-miR-513b CLIP-seq
MIRT1549413 hsa-miR-4719 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(9)
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0003713 Function Transcription coactivator activity TAS 10364255
GO:0005515 Function Protein binding IPI 25416956
GO:0005672 Component Transcription factor TFIIA complex IBA 21873635
GO:0005737 Component Cytoplasm IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
605358 30727 ENSG00000242441
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9UNN4
Protein name TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor)
Protein function May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03153 TFIIA 10 → 478 Transcription factor IIA, alpha/beta subunit Family
Tissue specificity TISSUE SPECIFICITY: Testis specific. Detected in adult testis mostly in round and elongating spermatids (at protein level). Detected in testis. {ECO:0000269|PubMed:10364255, ECO:0000269|PubMed:16525715}.
Sequence
Sequence length 478
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Basal transcription factors
Viral carcinogenesis 		 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (3)
Causal
Disease term Disease name dbSNP ID References
Leydig cell agenesis Leydig cell agenesis rs121912537, rs121912520, rs121912523, rs121912524, rs121912525, rs121912529, rs2104352652, rs71245621, rs121912536, rs121912538, rs121912539, rs144859947, rs773279269, rs1553387851, rs140568136
View all (1 more)
Pseudohermaphroditism Pseudohermaphroditism rs119481075, rs119481076, rs119481077, rs201115371, rs144809928, rs750481017, rs372027264, rs773720185, rs1554694264, rs1554694678, rs747724352, rs767765046, rs149607031, rs1554705693
Somatic leydig cell adenoma with male-limited precocious puberty Leydig Cell Adenoma, Somatic, with Male-Limited Precocious Puberty rs121912532
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Polycystic Ovary Syndrome Polycystic Ovary Syndrome GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Show/Hide Text Mining Associations (7)
Associations from Text Mining
Disease Name Relationship Type References
Azoospermia Associate 25374392
DNA Virus Infections Associate 23770943
Infertility Male Associate 23770943, 25374392
Macular Degeneration Associate 28775256
Oculocerebrorenal Syndrome Stimulate 23770943
Polycystic Ovary Syndrome Associate 22547425, 39273163
Polycystic Ovary Syndrome Stimulate 26305227