Gene Gene information from NCBI Gene database.
Entrez ID 11031
Gene name RAB31, member RAS oncogene family
Gene symbol RAB31
Synonyms (NCBI Gene)
Rab22B
Chromosome 18
Chromosome location 18p11.22
Summary Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009]
miRNA miRNA information provided by mirtarbase database.
633
miRTarBase ID miRNA Experiments Reference
MIRT021663 hsa-miR-140-3p Sequencing 20371350
MIRT022839 hsa-miR-124-3p Microarray 18668037
MIRT026067 hsa-miR-196a-5p Sequencing 20371350
MIRT720464 hsa-miR-1255b-2-3p HITS-CLIP 19536157
MIRT720463 hsa-miR-6834-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
46
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0001891 Component Phagocytic cup IEA
GO:0001891 Component Phagocytic cup ISS
GO:0003924 Function GTPase activity IBA
GO:0003924 Function GTPase activity IDA 11784320
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605694 9771 ENSG00000168461
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q13636
Protein name Ras-related protein Rab-31 (EC 3.6.5.2) (Ras-related protein Rab-22B)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:11784320). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form
PDB 2FG5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 7 168 Ras family Domain
Tissue specificity TISSUE SPECIFICITY: Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas. {ECO:0000269|PubMed:11784320}.
Sequence
Sequence length 194
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Endocytosis   Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs