RAB31 (RAB31, member RAS oncogene family)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11031 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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RAB31, member RAS oncogene family |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RAB31 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Rab22B |
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Chromosome
Chromosome number
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18 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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18p11.22 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q13636 | ||||||||||
| Protein name | Ras-related protein Rab-31 (EC 3.6.5.2) (Ras-related protein Rab-22B) | ||||||||||
| Protein function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:11784320). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form | ||||||||||
| PDB | 2FG5 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas. {ECO:0000269|PubMed:11784320}. | ||||||||||
| Sequence |
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| Sequence length | 194 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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