Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	11018
Gene name	Transmembrane p24 trafficking protein 1
Gene symbol	TMED1
Synonyms (NCBI Gene)	IL1RL1LGIl1rl1lTp24p24g1
Chromosome	19
Chromosome location	19p13.2
Summary	This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1

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miRTarBase ID	miRNA	Experiments	Reference
MIRT022713	hsa-miR-124-3p	Microarray	18668037
MIRT028588	hsa-miR-30a-5p	Proteomics	18668040
MIRT051161	hsa-miR-16-5p	CLASH	23622248
MIRT041623	hsa-miR-486-5p	CLASH	23622248
MIRT2128457	hsa-miR-1913	CLIP-seq
MIRT2128458	hsa-miR-1972	CLIP-seq
MIRT2128459	hsa-miR-3145-5p	CLIP-seq
MIRT2128460	hsa-miR-3184	CLIP-seq
MIRT2128461	hsa-miR-3188	CLIP-seq
MIRT2128462	hsa-miR-324-3p	CLIP-seq
MIRT2128463	hsa-miR-365	CLIP-seq
MIRT2128464	hsa-miR-3691-3p	CLIP-seq
MIRT2128465	hsa-miR-423-5p	CLIP-seq
MIRT2128466	hsa-miR-4257	CLIP-seq
MIRT2128467	hsa-miR-4707-3p	CLIP-seq
MIRT2128468	hsa-miR-4717-5p	CLIP-seq
MIRT2128469	hsa-miR-4728-5p	CLIP-seq
MIRT2128470	hsa-miR-670	CLIP-seq
MIRT2128471	hsa-miR-936	CLIP-seq
MIRT2350074	hsa-miR-1207-5p	CLIP-seq
MIRT2350075	hsa-miR-1271	CLIP-seq
MIRT2350076	hsa-miR-182	CLIP-seq
MIRT2350077	hsa-miR-2110	CLIP-seq
MIRT2350078	hsa-miR-3126-5p	CLIP-seq
MIRT2350079	hsa-miR-3150a-3p	CLIP-seq
MIRT2350080	hsa-miR-3175	CLIP-seq
MIRT2128464	hsa-miR-3691-3p	CLIP-seq
MIRT2128466	hsa-miR-4257	CLIP-seq
MIRT2350081	hsa-miR-4282	CLIP-seq
MIRT2350082	hsa-miR-4496	CLIP-seq
MIRT2128467	hsa-miR-4707-3p	CLIP-seq
MIRT2128469	hsa-miR-4728-5p	CLIP-seq
MIRT2350083	hsa-miR-4736	CLIP-seq
MIRT2350084	hsa-miR-4763-3p	CLIP-seq
MIRT2128470	hsa-miR-670	CLIP-seq
MIRT2350085	hsa-miR-939	CLIP-seq
MIRT2350086	hsa-miR-96	CLIP-seq
MIRT2128469	hsa-miR-4728-5p	CLIP-seq
MIRT2643577	hsa-miR-101	CLIP-seq
MIRT2350074	hsa-miR-1207-5p	CLIP-seq
MIRT2643578	hsa-miR-1224-5p	CLIP-seq
MIRT2643579	hsa-miR-124	CLIP-seq
MIRT2643580	hsa-miR-1250	CLIP-seq
MIRT2350075	hsa-miR-1271	CLIP-seq
MIRT2643581	hsa-miR-1283	CLIP-seq
MIRT2643582	hsa-miR-144	CLIP-seq
MIRT2350076	hsa-miR-182	CLIP-seq
MIRT2643583	hsa-miR-184	CLIP-seq
MIRT2128457	hsa-miR-1913	CLIP-seq
MIRT2350077	hsa-miR-2110	CLIP-seq
MIRT2643584	hsa-miR-2392	CLIP-seq
MIRT2643585	hsa-miR-2467-5p	CLIP-seq
MIRT2350078	hsa-miR-3126-5p	CLIP-seq
MIRT2350079	hsa-miR-3150a-3p	CLIP-seq
MIRT2350080	hsa-miR-3175	CLIP-seq
MIRT2643586	hsa-miR-3180-5p	CLIP-seq
MIRT2128460	hsa-miR-3184	CLIP-seq
MIRT2128461	hsa-miR-3188	CLIP-seq
MIRT2128462	hsa-miR-324-3p	CLIP-seq
MIRT2643587	hsa-miR-329	CLIP-seq
MIRT2643588	hsa-miR-3607-5p	CLIP-seq
MIRT2643589	hsa-miR-3620	CLIP-seq
MIRT2643590	hsa-miR-362-3p	CLIP-seq
MIRT2643591	hsa-miR-3689a-3p	CLIP-seq
MIRT2643592	hsa-miR-3689c	CLIP-seq
MIRT2128464	hsa-miR-3691-3p	CLIP-seq
MIRT2643593	hsa-miR-370	CLIP-seq
MIRT2643594	hsa-miR-3714	CLIP-seq
MIRT2643595	hsa-miR-371b-3p	CLIP-seq
MIRT2643596	hsa-miR-3910	CLIP-seq
MIRT2643597	hsa-miR-3944-5p	CLIP-seq
MIRT2128465	hsa-miR-423-5p	CLIP-seq
MIRT2643598	hsa-miR-4252	CLIP-seq
MIRT2128466	hsa-miR-4257	CLIP-seq
MIRT2350081	hsa-miR-4282	CLIP-seq
MIRT2643599	hsa-miR-4284	CLIP-seq
MIRT2350082	hsa-miR-4496	CLIP-seq
MIRT2643600	hsa-miR-4537	CLIP-seq
MIRT2643601	hsa-miR-4640-5p	CLIP-seq
MIRT2643602	hsa-miR-4667-3p	CLIP-seq
MIRT2643603	hsa-miR-4691-3p	CLIP-seq
MIRT2128467	hsa-miR-4707-3p	CLIP-seq
MIRT2643604	hsa-miR-4726-5p	CLIP-seq
MIRT2128469	hsa-miR-4728-5p	CLIP-seq
MIRT2350083	hsa-miR-4736	CLIP-seq
MIRT2643605	hsa-miR-4749-3p	CLIP-seq
MIRT2643606	hsa-miR-4751	CLIP-seq
MIRT2350084	hsa-miR-4763-3p	CLIP-seq
MIRT2643607	hsa-miR-501-3p	CLIP-seq
MIRT2643608	hsa-miR-502-3p	CLIP-seq
MIRT2643609	hsa-miR-506	CLIP-seq
MIRT2643610	hsa-miR-582-5p	CLIP-seq
MIRT2643611	hsa-miR-665	CLIP-seq
MIRT2128470	hsa-miR-670	CLIP-seq
MIRT2128471	hsa-miR-936	CLIP-seq
MIRT2350085	hsa-miR-939	CLIP-seq
MIRT2350086	hsa-miR-96	CLIP-seq
MIRT2643577	hsa-miR-101	CLIP-seq
MIRT2350074	hsa-miR-1207-5p	CLIP-seq
MIRT2643579	hsa-miR-124	CLIP-seq
MIRT2643580	hsa-miR-1250	CLIP-seq
MIRT2350075	hsa-miR-1271	CLIP-seq
MIRT2643581	hsa-miR-1283	CLIP-seq
MIRT2643582	hsa-miR-144	CLIP-seq
MIRT2350076	hsa-miR-182	CLIP-seq
MIRT2128457	hsa-miR-1913	CLIP-seq
MIRT2350077	hsa-miR-2110	CLIP-seq
MIRT2693272	hsa-miR-2355-3p	CLIP-seq
MIRT2643584	hsa-miR-2392	CLIP-seq
MIRT2643585	hsa-miR-2467-5p	CLIP-seq
MIRT2693273	hsa-miR-3121-5p	CLIP-seq
MIRT2350078	hsa-miR-3126-5p	CLIP-seq
MIRT2350079	hsa-miR-3150a-3p	CLIP-seq
MIRT2350080	hsa-miR-3175	CLIP-seq
MIRT2643586	hsa-miR-3180-5p	CLIP-seq
MIRT2128460	hsa-miR-3184	CLIP-seq
MIRT2128461	hsa-miR-3188	CLIP-seq
MIRT2128462	hsa-miR-324-3p	CLIP-seq
MIRT2643587	hsa-miR-329	CLIP-seq
MIRT2643588	hsa-miR-3607-5p	CLIP-seq
MIRT2643589	hsa-miR-3620	CLIP-seq
MIRT2643590	hsa-miR-362-3p	CLIP-seq
MIRT2643591	hsa-miR-3689a-3p	CLIP-seq
MIRT2643592	hsa-miR-3689c	CLIP-seq
MIRT2128464	hsa-miR-3691-3p	CLIP-seq
MIRT2643593	hsa-miR-370	CLIP-seq
MIRT2643594	hsa-miR-3714	CLIP-seq
MIRT2643595	hsa-miR-371b-3p	CLIP-seq
MIRT2643596	hsa-miR-3910	CLIP-seq
MIRT2643597	hsa-miR-3944-5p	CLIP-seq
MIRT2128465	hsa-miR-423-5p	CLIP-seq
MIRT2128466	hsa-miR-4257	CLIP-seq
MIRT2350081	hsa-miR-4282	CLIP-seq
MIRT2643599	hsa-miR-4284	CLIP-seq
MIRT2350082	hsa-miR-4496	CLIP-seq
MIRT2643600	hsa-miR-4537	CLIP-seq
MIRT2643601	hsa-miR-4640-5p	CLIP-seq
MIRT2693274	hsa-miR-4646-3p	CLIP-seq
MIRT2643602	hsa-miR-4667-3p	CLIP-seq
MIRT2128467	hsa-miR-4707-3p	CLIP-seq
MIRT2643604	hsa-miR-4726-5p	CLIP-seq
MIRT2128469	hsa-miR-4728-5p	CLIP-seq
MIRT2350083	hsa-miR-4736	CLIP-seq
MIRT2643605	hsa-miR-4749-3p	CLIP-seq
MIRT2350084	hsa-miR-4763-3p	CLIP-seq
MIRT2643607	hsa-miR-501-3p	CLIP-seq
MIRT2643608	hsa-miR-502-3p	CLIP-seq
MIRT2643609	hsa-miR-506	CLIP-seq
MIRT2643610	hsa-miR-582-5p	CLIP-seq
MIRT2643611	hsa-miR-665	CLIP-seq
MIRT2128470	hsa-miR-670	CLIP-seq
MIRT2128471	hsa-miR-936	CLIP-seq
MIRT2350085	hsa-miR-939	CLIP-seq
MIRT2350086	hsa-miR-96	CLIP-seq

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002376	Process	Immune system process	IEA
GO:0005102	Function	Signaling receptor binding	TAS	8621446
GO:0005515	Function	Protein binding	IPI	8621446
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA	12237308
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IBA
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IDA	12237308
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	12237308
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006886	Process	Intracellular protein transport	IBA
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0007030	Process	Golgi organization	IBA
GO:0007165	Process	Signal transduction	TAS	8621446
GO:0007267	Process	Cell-cell signaling	TAS	8621446
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0030134	Component	COPII-coated ER to Golgi transport vesicle	IBA
GO:0033116	Component	Endoplasmic reticulum-Golgi intermediate compartment membrane	IEA
GO:0045087	Process	Innate immune response	IEA

MIM	HGNC	e!Ensembl
605395	17291	ENSG00000099203

Q13445

Protein name

Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1)

Protein function

Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat fo

PDB

7RRM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01105	EMP24_GP25L	33 → 220	emp24/gp25L/p24 family/GOLD	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:8621446}.

Sequence

MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEY
QVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF
FELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEA
RDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT

Sequence length

227

Interactions

View interactions

TMED1 (transmembrane p24 trafficking protein 1)