KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10945 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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KDEL endoplasmic reticulum protein retention receptor 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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KDELR1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ERD2, ERD2.1, HDEL, PM23 |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19q13.33 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-ter |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P24390 | ||||||||||
Protein name | ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) (Putative MAPK-activating protein PM23) | ||||||||||
Protein function | Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. {ECO:0000269|PubMed:11703931, ECO:0000269|PubMed:14 | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 212 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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