PAPOLA (poly(A) polymerase alpha)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10914 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Poly(A) polymerase alpha |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PAPOLA |
Synonyms (NCBI Gene)
Gene synonyms aliases
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PAP, PAP-alpha |
Chromosome
Chromosome number
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14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q32.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3`-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have b |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | P51003 | ||||||||||||||||||||
Protein name | Poly(A) polymerase alpha (PAP-alpha) (EC 2.7.7.19) (Polynucleotide adenylyltransferase alpha) | ||||||||||||||||||||
Protein function | Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor | ||||||||||||||||||||
PDB | 8R8R | ||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 745 | ||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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